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Displaying drugs 576 - 600 of 765 in total
RU84687 is a subnanomolar and Src SH2 selective binder.
Experimental
Matched Synonyms: … N-acetyl-N-[1-(1,1'-biphenyl-4-ylmethyl)-2-oxoazepan-3-yl]-3-formyl-O-phosphonotyrosinamide …
Matched Description: … RU84687 is a subnanomolar and Src SH2 selective binder. …
Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain, or first line as a topical treatment of corticosteroid responsive dermatoses. Triamcinolone is more...
Approved
Vet approved
Matched Iupac: … hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Matched Description: … Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and ... or first line as a topical treatment of corticosteroid responsive dermatoses. ... [L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] …
Matched Mixtures name: … Kenacomb Ont ... Viaderm Kc Ont ... Point Of Care Kit KM …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... triamcinolone and antiseptics ... triamcinolone and antibiotics ... triamcinolone and antiinfectives …
Matched Products: … Up and Up Nasal Allergy ... Foster and Thrive 24 Hour Nasal Allergy ... Kenalog Ont 0.1% …
Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Description: … [L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today. ... [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two ... due to a significant number of reports concerning chemical and thermal burns associated with the use …
Matched Mixtures name: … Burn O Sol Spray ... ChloraPrep One-Step ... ChloraPrep One-Step …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Alimentary Tract and Metabolism ... Biguanides and Amidines ... Antiseptics and Disinfectants ... Mouthwashes and Gargles …
Matched Products: … Foster and Thrive ... 3M AVAGARD 9232 ANTISEPTIC HAND AND BODY WASH CLORHEXIDINE GLUCONATE 2% W/W SOLUTION BOTTE . ... PLAK OUT
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Synonyms: … O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->4)-O-(6-AMINO-6-DEOXY-.ALPHA. ... D-STREPTAMINE, O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->6)-O-(6-AMINO-6-DEOXY-.ALPHA. …
Matched Iupac: … amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy ... }-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide …
Matched Description: … of breath and the coughing up of blood. ... M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil. ... Symptoms of this disease include a persistent cough, fatigue, weight loss, night sweats, and shortness …
Matched Categories: … cefepime and amikacin …
Ubidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. The ubidecarenone is...
Approved
Investigational
Nutraceutical
Matched Description: … From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number ... of isoprenyl subunits in its tail. ... [A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative …
Matched Mixtures name: … Formula O.C. ... Vitamin E and Coq10 ... Co-q10 and Vitamin E …
Matched Categories: … Enzymes and Coenzymes ... Diet, Food, and Nutrition …
Matched Products: … Coenzyme Q10 With Hawthorn Extract and Citrus Bioflavonoids …
Fludiazepam is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a scheduled drug in the U.S., but is approved for use in Japan.
Experimental
Illicit
Matched Synonyms: … 7-chloro-5-(o-Fluorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one
Matched Iupac: … 7-chloro-5-(2-fluorophenyl)-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
Matched Description: … It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
Experimental
Matched Synonyms: … O-((Aminoiminomethyl)amino)-L-homoserine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … 1-(3-O-sulfo-beta-D-galactosyl)-N-[(15Z)-tetracos-15-enoyl]sphingosine …
Matched Iupac: … ,3R,4S,5S,6R)-3,5-dihydroxy-2-{[(2S,3R,4E)-3-hydroxy-2-[(15Z)-tetracos-15-enamido]octadec-4-en-1-yl]oxy
Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow...
Approved
Vet approved
Matched Description: … Oxygen is an element displayed by the symbol O, and atomic number 8. ... Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing ... any disease that impairs the body's ability to take up and use gaseous oxygen. …
Matched Mixtures name: … Carbon Dioxide and Oxygen Mixture, Compressed, Oxidizing, N.O.S. ... Co-NE-O2-N2 Mixture ... Co-HE-O2-N2 Mixture …
Matched Products: … OSSIGENO FARMA GAS MEDICAL AND TECHNICAL GASES ... Ez-OX ... EZ-Ox
Experimental
Matched Synonyms: … (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-2-O-{2-[(piperidin-3- ... ylmethyl)amino]ethyl}-β-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-α-D-glucopyranoside …
Matched Name: … (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-2-O-{2-[(piperidin ... -3-ylmethyl)amino]ethyl}-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside …
Matched Iupac: … }-5-(hydroxymethyl)-3-(2-{[(piperidin-3-yl)methyl]amino}ethoxy)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy ... )-4,6-diamino-2-{[(2S,3R,4R,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy
Approved
Experimental
Matched Synonyms: … Ethyl o-hydroxybenzoate …
Investigational
Matched Synonyms: … -neuraminic acid, n-acetyl-2-o-(7,26-dioxo-10,13,16,19,22-pentaoxa-6,25-diazapentaconta-35,37-diyn-1- …
Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. It is a beta-2-adrenergic receptor agonist. Bitolterol was withdrawn from the market by Elan Pharmaceuticals in 2001.
Withdrawn
Matched Synonyms: … 4-(2-(tert-butylamino)-1-hydroxyethyl)-o-phenylene di-p-toluate ... 4-[2-(tert-butylamino)-1-hydroxyethyl]-o-phenylene di-p-toluate …
Matched Description: … Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. …
Gemcitabine elaidate has been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and Metastatic Pancreatic Adenocarcinoma.
Investigational
Matched Synonyms: … 5'-O-(trans-9"-octadecenoyl)-1-beta-D-2'deoxy-2',2'-difluorocytidine ... 5'-O-(TRANS-9''-OCTADECENOYL)-1-.BETA.-D-2'DEOXY-2',2'-DIFLUOROCYTIDINE …
Matched Iupac: … [(2R,3R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4,4-difluoro-3-hydroxyoxolan-2-yl]methyl (9E) …
Matched Description: … Lung Cancer, and Metastatic Pancreatic Adenocarcinoma. ... Gemcitabine elaidate has been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect. However, this leads to poorer water solubility, which was compensated by the addition of the chloride...
Approved
Investigational
Matched Synonyms: … L-OHP ... (SP-4-2-(1R-TRANS))-(1,2-CYCLOHEXANEDIAMINE-N,N')(ETHANEDIOATO(2-)-O,O')PLATINUM …
Matched Description: … [A797] Oxaliplatin was approved by the FDA on January 9, 2004 and is currently marketed by Sanofi-Aventis ... refractory to an initial fluorouracil and leucovorin combination. ... Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … AL OXA ® SOLUCION CONCENTRADA PARA INFUSION ... O-PLAT 50 MG POLVO LIOFILIZADO PARA INYECC ION ... O-PLAT 100 MG POLVO LIOFILIZADO PARA INYECCION …
Novobiocin is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189) Novobiocin sodium, a salt form of novobiocin, was initially approved in September 1964...
Approved
Investigational
Vet approved
Withdrawn
Matched Synonyms: … N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-β-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-chromen …
Matched Iupac: … -2H-chromen-7-yl}oxy)-3-methoxy-2,2-dimethyloxan-4-yl carbamate ... (3R,4S,5R,6R)-5-hydroxy-6-({4-hydroxy-3-[4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamido]-8-methyl-2-oxo
Matched Description: … novobiocin, was initially approved in September 1964 and was indicated for the treatment of serious ... Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. ... In 2009, the FDA determined novobiocin sodium was withdrawn from sale for reasons of safety or effectiveness …
A nucleoside triphosphate analogue that is ATP in which one of the oxygens attached to 3-phosphate group is replaced by sulfur.
Experimental
Matched Synonyms: … Adenosine 5-O-(3-thiotriphophate) ... Adenosine 5'-O-(3-thiotriphosphate) …
Matched Iupac: … ](hydroxy)phosphoryl}oxy)phosphonothioic acid ... ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy
Matched Description: … A nucleoside triphosphate analogue that is ATP in which one of the oxygens attached to 3-phosphate group …
Matched Categories: … Indicators and Reagents ... Nucleic Acids, Nucleotides, and Nucleosides ... Compounds used in a research, industrial, or household setting …
Esculin is found in barley. Vitamin C2 is generally considered a bioflavanoid, related to vitamin P esculin is a glucoside that naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and in daphnin (the dark green resin of Daphne mezereum). Esculin belongs to the family of Glycosyl...
Approved
Matched Synonyms: … Esculetin 6-O-glucoside ... 6,7-Dihydroxycoumarin-6-O-glucoside ... 6-(beta-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one
Matched Iupac: … 7-hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2H-chromen-2-one
Matched Description: … naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and ... , or Se- glycosidic bond. ... Esculin belongs to the family of Glycosyl Compounds. …
Matched Mixtures name: … Proctosone Ont
Omfiloctocog alfa is under investigation in clinical trial NCT03947567 (Safety and Efficacy of Long-term Treatment With SCT800 in Previously Treated Hemophilia a Patients.).
Investigational
Matched Synonyms: … DOMAINS A1-A1-A2-A2 (1-740), THE B-DOMAIN N-AND C-TERMINAL FRAGMENTS (741-745) ... PROCOAGULANT COMPONENT) WITH DELETED B-DOMAIN (746-1639)-SEQUENCE: SINGLE-CHAIN RECOMBINANT FVIII COMPOSED OF
Matched Description: … Omfiloctocog alfa is under investigation in clinical trial NCT03947567 (Safety and Efficacy of Long-term …
Mitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and their production of hormones. It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma and is used off-label for the...
Approved
Matched Synonyms: … o,p'-DDD …
Matched Description: … metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and their ... It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma[A263010] and is ... used off-label for the management of Cushing's syndrome. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
NA-831 (Traneurocin), is under investigation in two clinical trials: NCT03538522 (completed, for mild cognitive impairment and Alzheimer’s disease) and NCT04452565 (unknown status, combination therapy with Atazanavir and Dexamethasone for COVID-19).
Experimental
Matched Synonyms: … Cyclo(pro-O-gly) …
Matched Description: … Alzheimer’s disease) and NCT04452565 (unknown status, combination therapy with Atazanavir and Dexamethasone ... is under investigation in two clinical trials: NCT03538522 (completed, for mild cognitive impairment and
Matched Categories: … Amino Acids, Peptides, and Proteins …
WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). It was granted FDA orphan designation for the treatment of glioblastoma multiforme.
Investigational
Matched Synonyms: … 3,6-di-O-acetyl-2-deoxy-D-glucopyranose ... an acetic acid diester of 2-deoxy-D-glucose …
Matched Description: … WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). ... It was granted FDA orphan designation for the treatment of glioblastoma multiforme.[L47361] …
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Approved
Experimental
Investigational
Matched Synonyms: … 5-O-phosphono-α-D-ribofuranosyl diphosphate …
Matched Name: … 5-O-phosphono-alpha-D-ribofuranosyl diphosphate …
Matched Iupac: … [({[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic …
Matched Description: … The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides …
Experimental
Matched Name: … 4-O-methyl-beta-D-glucuronic acid …
Experimental
Matched Name: … 2,3-Di-O-Sulfo-Alpha-D-Glucopyranose …
Displaying drugs 576 - 600 of 765 in total