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Displaying drugs 576 - 600 of 15155 in total

Nabumetone

Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Description: … Nabumetone was developed by Smithkline Beecham under the trade name Relafen and first received FDA approval ... [label,A178903] The molecule itself is a pro-drug with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …

Holcus lanatus pollen

Holcus lanatus pollen is the pollen of the Holcus lanatus plant. Holcus lanatus pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Mixture of Standardized and Non-Standardized Coastal Grasses ... Mixture of Twenty-Two Standardized and Non-Standardized Grasses …

Cyd dengue virus serotype 1 live (attenuated) antigen

Approved
Matched Mixtures name: … DENGVAXIA MD, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION ... DENGVAXIA, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION …

Cyd dengue virus serotype 2 live (attenuated) antigen

Approved
Matched Mixtures name: … DENGVAXIA MD, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION ... DENGVAXIA, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION …

Etonogestrel

Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.
Approved
Investigational
Matched Description: … [A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA …
Matched Mixtures name: … Etonogestrel and Ethinyl Estradiol ... Etonogestrel and Ethinyl Estradiol Vaginal ... Etonogestrel and Ethinyl Estradiol Vaginal Ring …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Combination Contraceptives (with Estrogen and derivatives) …

Glimepiride

First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive...
Approved
Matched Description: … long-term microvascular and macrovascular complications that lead to co-morbidities and mortalities. ... worldwide; it is characterized by insulin resistance in accordance with progressive β cell failure and ... present,[A177715] as they work by stimulating the release of insulin from the pancreatic beta cells and …
Matched Mixtures name: … Pioglitazone and Glimepiride ... Pioglitazone and Glimepiride ... Pioglitazone hydrochloride and glimepiride …
Matched Categories: … Alimentary Tract and Metabolism ... glimepiride and pioglitazone ... glimepiride and rosiglitazone …

Oxeladin

Withdrawn from the Canadian, US, and UK markets in 1976 due to carcinogenicity.
Approved
Withdrawn
Matched Description: … Withdrawn from the Canadian, US, and UK markets in 1976 due to carcinogenicity. …
Matched Categories: … Cough and Cold Preparations …

Dihydrotachysterol

A vitamin D that can be regarded as a reduction product of vitamin D2.
Approved
Matched Categories: … Diet, Food, and Nutrition ... Vitamin D and Analogues ... Alimentary Tract and Metabolism …

Pentoxyverine

Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant , and local anesthetic properties. It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists . Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The...
Approved
Investigational
Withdrawn
Matched Description: … Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. ... It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and ... carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant [A32717], and …
Matched Categories: … Cough and Cold Preparations …

Fusafungine

Fusafungine is an antibiotic from Fusarium lateririum, and is used for the treatment of respiratory infections.
Approved
Withdrawn
Matched Description: … Fusafungine is an antibiotic from Fusarium lateririum, and is used for the treatment of respiratory infections …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Ombitasvir

Ombitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Description: … FDA- and Health Canada-approved product Technivie. ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... Ombitasvir is an inhibitor of NS5A, a protein essential for viral replication and virion assembly [FDA …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ombitasvir, paritaprevir and ritonavir ... dasabuvir, ombitasvir, paritaprevir and ritonavir …

Papain

Papain, also known as papaya proteinase I, is a cysteine protease (EC 3.4.22.2) enzyme that is found in species of papaya, Carica papaya and Vasconcellea cundinamarcensis. The enzyme is found to be localized in the skin of papaya, and is collected from slashed unripe papayas as a crude latex. Papain...
Approved
Matched Description: … has also shown to have anthelmintic and tooth-whitening properties. ... Papain is used in food, pharmaceutical, textile, and cosmetic industries. ... I, is a cysteine protease (EC 3.4.22.2) enzyme that is found in species of papaya, _Carica papaya_ and …
Matched Mixtures name: … Bromelain and Papain Tab ... NATURE'S BOUNTY NATUREL B-COMPLEX AND B-12 TABLET, 90 ADET …
Matched Categories: … Enzymes and Coenzymes …

Lypressin

Approved
Matched Iupac: … -carbonyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-N-[(C-hydroxycarbonimidoyl)methyl]hexanimidic acid …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Vasopressin and Analogues ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Strontium ranelate

Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee. This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and,...
Approved
Withdrawn
Matched Description: … Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. ... intrinsic bone tissue quality and microarchitecture in osteoporosis by way of a number of cellular and ... presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and …
Matched Categories: … strontium ranelate and colecalciferol ... Drugs Affecting Bone Structure and Mineralization …

Lutropin alfa

Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units. Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for use in...
Approved
Matched Description: … Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for ... biological activity of endogenous LH; an acute rise of LH, or LH surge, in females triggers ovulation and …
Matched Mixtures name: … Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu …
Matched Categories: … Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …

Zinc sulfate, unspecified form

Zinc sulfate is a common zinc supplement in parenteral nutrition.[A216916,L12888]
Approved
Experimental
Matched Mixtures name: … Up and Up Ultra Itchy Relief ... Seasonal itchy and Red eye relief ... Soundbody Seasonal itchy and Red eye relief …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Ivosidenib

Ivosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. IDH1 is an enzyme that is often mutated and overexpressed in some cancers, leading to aberrant cell growth and proliferation. Ivosidenib inhibits mutated IDH1, blocking the enzymatic activity and further differentiation of cancer cells. Ivosidenib was granted accelerated approval by the FDA...
Approved
Investigational
Matched Description: … and proliferation. ... IDH1 is an enzyme that is often mutated and overexpressed in some cancers, leading to aberrant cell growth ... [A248750] Ivosidenib inhibits mutated IDH1, blocking the enzymatic activity and further differentiation …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Turpentine

Turpentine, also known as spirit of turpentine, oil of turpentine, and wood turpentine, is a liquid extracted from live trees, mainly pine, through distillation of resin. It is used as a solvent and base material in organic synthesis reactions. Turpentine is composed of terpenes, mainly the monoterpenes alpha-pinene and beta-pinene...
Approved
Experimental
Matched Description: … amounts of carene, camphene, dipentene, and terpinolene. ... It is used as a solvent and base material in organic synthesis reactions. ... Turpentine, also known as spirit of turpentine, oil of turpentine, and wood turpentine, is a liquid extracted …
Matched Mixtures name: … Jack and Jill Rub ... Half and Half Balm …

Sotrovimab

Sotrovimab (VIR-7831), also known as GSK4182136, is a monoclonal antibody that can neutralize the SARS-CoV-2 virus. Sotrovimab was initially been granted emergency use authorization (EUA) to treat mild-to-moderate COVID-19 on May 26, 2021, based on interim results from a clinical trial, where sotrovimab was found to reduce the risk of...
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …

Elbasvir

Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in...
Approved
Matched Description: … with or without [ribavirin] depending on the presence of resistance-associated amino acid substitutions ... [A19593] Substitutions at amino acid positions 28, 30, 31, or 93 are known to confer resistance to elbasvir ... for genotype 1 and 97% and 100% for genotype 4 after 12 weeks of treatment. …
Matched Categories: … elbasvir and grazoprevir …

Dermatophagoides farinae

Dermatophagoides farinae extracts are sterile solutions used for intradermal testing or subcutaneous immunotherapy. This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Approved
Matched Mixtures name: … Standardized Mite Mix Dermatophagoides farinae and Dermatophagoides pteronyssinus ... Standardized Mite Mix Dermatophagoides farinae and Dermatophagoides pteronyssinus ... Standardized Mite Mix, Dermatophagoides pteronyssinus and Dermatophagoides farinae, 10000 AU per mL …

Insulin glulisine

Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … B3 is replaced by lysine and the lysine at position B29 is replaced by glutamic acid. ... This recombinant hormone differs from native human insulin in that the amino acid asparagine at position ... and proteolysis among many other functions. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Aripiprazole lauroxil

Aripiprazole lauroxil is a long-acting injectable atypical antipsychotic drug used in the treatment of schizophrenia in adult patients. It is a prodrug of aripiprazole, which acts as a partial agonist at the D2 and 5-HT1A receptors, and as an antagonist at the 5-HT2A receptors . Affecting about 1% of the...
Approved
Investigational
Matched Description: … It is a prodrug of [aripiprazole], which acts as a partial agonist at the D2 and 5-HT1A receptors, and ... catanoia, and negative symptoms that include social withdrawal, anhedonia, and flattening of emotional ... patients are faced with social stigma and discriminations. …
Matched Categories: … Aripiprazole and prodrugs …

Certolizumab pegol

Certolizumab pegol is a pegylated monoclonal antibody against the tumor necrosis factor-alpha (TNF-alpha). It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacing the Fc antibody region. The absence of the Fc region was ideated...
Approved
Matched Description: … [A176606] It was developed and manufactured by UCB Pharma, first FDA approved in 2008[L45018] and updated ... [A176606] Certolizumab does not require glycosylation for active function and hence, its production ... The absence of the Fc region was ideated to prevent complement fixation and antibody-mediated cytotoxicity …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Ibrutinib

Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in...
Approved
Matched Description: … It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies ... [A32299] Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in November 2013 ... [L45894] Ibrutinib was approved by the EMA in October 2014 [L45884] and by Health Canada in November …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Displaying drugs 576 - 600 of 15155 in total