Displaying drugs 601 - 625 of 935 in total
7-(alpha-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one
Experimental
Matched Synonyms: … 7-(alpha-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one ... 4-Methylumbelliferyl α-D-glucoside …
Matched Name: … 7-(alpha-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one …
Matched Name: … 7-(alpha-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one …
2-aminoisobutyric acid
Experimental
Matched Synonyms: … alpha-Methylalanine ... alpha-Aminoisobutyric acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Lofexidine
Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved for the treatment of opioid withdrawal in the United Kingdom in 1992. It was first studied for use as an antihypertensive in 1980, but its researched was stopped as it was found less effective for the treatment...
Approved
Investigational
Matched Synonyms: … 2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazoline …
Matched Description: … [T209] Lofexidine was developed by US Woldmeds LLC and it was approved by the FDA on May 16, 2018. ... Lofexidine was then repurposed for the treatment of opioid withdrawal, as it was seen to be more economical and ... Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved …
Matched Categories: … Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Matched Description: … [T209] Lofexidine was developed by US Woldmeds LLC and it was approved by the FDA on May 16, 2018. ... Lofexidine was then repurposed for the treatment of opioid withdrawal, as it was seen to be more economical and ... Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved …
Matched Categories: … Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Heptyl glucoside
Experimental
Matched Synonyms: … Heptyl glucoside ... 1-Heptyl beta-D-glucoside ... n-Heptyl beta-D-glucoside …
Matched Name: … Heptyl glucoside …
Matched Name: … Heptyl glucoside …
Diethylpropion
A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Approved
Illicit
Matched Synonyms: … alpha-Benzoyltriethylamine ... alpha-Diethylaminopropiophenone …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Categories: … Alimentary Tract and Metabolism …
Idursulfase
Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various...
Approved
Matched Synonyms: … Alpha-L-iduronate sulfate sulfatase …
Matched Description: … -sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and ... heparan sulfate in the lysosomes of various cell types. ... Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme …
Matched Description: … -sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and ... heparan sulfate in the lysosomes of various cell types. ... Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme …
(2R,3R,4R,5R)-3,4-Dihydroxy-N,N'-bis[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-2,5-bis(2-phenylethyl)hexanediamide
Experimental
Matched Synonyms: … Diol-Based HIV-1 protease inhibitor 4 …
Nomegestrol acetate
Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
Approved
Investigational
Matched Synonyms: … 17-alpha-Acetoxy-6-methyl-19-nor-4,6-pregnadiene-3,20-dione ... 17-alpha-Hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione acetate …
Matched Description: … acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) …
Matched Description: … acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) …
LSTA1
Investigational
Matched Synonyms: … L-cysteine, l-cysteinyl-l-arginylglycyl-l-.alpha.-aspartyl-l-lysylglycyl-l-prolyl-l-.alpha. …
Interferon alfa-n1
Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated. This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon genes.
Approved
Investigational
Matched Synonyms: … Interferon alpha-n1 (INS) …
Matched Description: … from individual alpha interferon genes. ... Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least ... This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … from individual alpha interferon genes. ... Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least ... This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Etryptamine
In the 1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was developed in the United States by the Upjohn chemical company for use as an antidepressant. αET was an FDA approved antidepressant under the name Monase. However, in 1962, after the discovery of an unacceptable incidence of agranulocytosis,...
Illicit
Investigational
Withdrawn
Matched Synonyms: … alpha-ethyltryptamine …
Matched Description: … αET is a stimulant and hallucinogen, but it is less stimulating and hallucinogenic than alpha-methyltryptamine ... In the 1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was ... the discovery of an unacceptable incidence of agranulocytosis, the development of Monase was halted and …
Matched Salts name: … Alpha-ethyltryptamine acetate …
Matched Description: … αET is a stimulant and hallucinogen, but it is less stimulating and hallucinogenic than alpha-methyltryptamine ... In the 1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was ... the discovery of an unacceptable incidence of agranulocytosis, the development of Monase was halted and …
Matched Salts name: … Alpha-ethyltryptamine acetate …
N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine
Experimental
Matched Synonyms: … Glycyl-L-alpha-amino-epsilon-pimelyl-D-alanyl-D-alanine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
6-o-Capryloylsucrose
Experimental
Matched Synonyms: … alpha-D-Glucopyranoside, 6-O-(1-oxooctyl)-beta-D-fructofuranosyl …
Chymotrypsin
Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides. It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. Like most proteolytic enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in presence...
Approved
Vet approved
Matched Synonyms: … alpha-Chymotrypsin …
Matched Description: … It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. ... Chymotrypsin is the most abundant pancreatic proteases that represent up to 10-20% of the total protein ... Chymotrypsin contains both the catalytic triad and oxyanion hole, and the tertiary structure of chymotrypsin …
Matched Categories: … Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Serine Proteases …
Matched Description: … It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. ... Chymotrypsin is the most abundant pancreatic proteases that represent up to 10-20% of the total protein ... Chymotrypsin contains both the catalytic triad and oxyanion hole, and the tertiary structure of chymotrypsin …
Matched Categories: … Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Serine Proteases …
PIK3CA
PIK3CA is under investigation in clinical trial NCT02957266 (Cervical Cancer Radiotherapy by Use of VMAT, Individualized Polyradiosensitization and Interstitial Brachytherapy).
Investigational
Matched Synonyms: … Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform …
Matched Description: … trial NCT02957266 (Cervical Cancer Radiotherapy by Use of VMAT, Individualized Polyradiosensitization and …
Matched Description: … trial NCT02957266 (Cervical Cancer Radiotherapy by Use of VMAT, Individualized Polyradiosensitization and …
Prolease-r-hFSH
Prolease-r-hFSH is a recombinant human follicle stimulating hormone (r-hFSH) with Alkermes' ProLease injectable sustained release drug delivery technology. It provides patients with long term therapeutic benefit from a single administration rather than multiple injections.
Investigational
Matched Name: … Prolease-r-hFSH …
Matched Description: … Prolease-r-hFSH is a recombinant human follicle stimulating hormone (r-hFSH) with Alkermes' ProLease …
Matched Description: … Prolease-r-hFSH is a recombinant human follicle stimulating hormone (r-hFSH) with Alkermes' ProLease …
Trans-O-Hydroxy-Alpha-Methyl Cinnamate
Experimental
Matched Name: … Trans-O-Hydroxy-Alpha-Methyl Cinnamate …
Thymalfasin
Thymalfasin is a chemically synthesized version of thymosin alpha 1 that is identical to human thymosin alpha 1. Thymosin alpha 1 is an acetylated polypeptide. Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. It is also used to boost the...
Investigational
Matched Synonyms: … Thymosin alpha1 (human) …
Matched Description: … Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. ... alpha 1. ... Thymosin alpha 1 is an acetylated polypeptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. ... alpha 1. ... Thymosin alpha 1 is an acetylated polypeptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Ulinastatin
Ulinastatin has been investigated for the prevention of Cardiovascular Disease and Adverse Reaction to Drug.
Investigational
Matched Synonyms: … Recombinant Truncated SPINT2 Protease Inhibitor …
Matched Description: … Ulinastatin has been investigated for the prevention of Cardiovascular Disease and Adverse Reaction to …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Protease Inhibitors ... Proteinase Inhibitors ... Serine Protease Inhibitors …
Matched Description: … Ulinastatin has been investigated for the prevention of Cardiovascular Disease and Adverse Reaction to …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Protease Inhibitors ... Proteinase Inhibitors ... Serine Protease Inhibitors …
Travoprost
Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective FP prostanoid receptor agonist. It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity at the prostanoid receptor, reporting a higher...
Approved
Matched Synonyms: … (1R-(1.ALPHA. ... ISOPROPYL (Z)-7-((1R,2R,3R,5S)-3,5-DIHYDROXY-2-((1E,3R)-3-HYDROXY-4-((.ALPHA.,.ALPHA.,.ALPHA. ... (Z),2.BETA.(1E,3R*),3.ALPHA.,5.ALPHA.))-7-(3,5-DIHYDROXY-2-(3-HYDROXY-4-(3-(TRIFLUOROMETHYL)PHENOXY)- …
Matched Description: … Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective ... It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. ... [L49434] Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Description: … Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective ... It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. ... [L49434] Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Acazicolcept
Investigational
Matched Synonyms: … cell costimulator ligand variant immunoglobulin domain designed to inhibit simultaneously the CD28 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ciprofloxacin
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493]
The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Description: … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration …
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Fluocinolone Acetonide …
Matched Salts name: … Ciprofloxacin lactate …
Matched Categories: … ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... ciprofloxacin and metronidazole ... Drug-Related Side Effects and Adverse Reactions ... Ophthalmological and Otological Preparations …
Matched Products: … Ciprofloxacin and Dextrose ... CILOXAN STERILE OPHTHALMIC AND OTIC SOLUTION 0.3% ... CIPROFLOXACIN LACTATE …
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Fluocinolone Acetonide …
Matched Salts name: … Ciprofloxacin lactate …
Matched Categories: … ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... ciprofloxacin and metronidazole ... Drug-Related Side Effects and Adverse Reactions ... Ophthalmological and Otological Preparations …
Matched Products: … Ciprofloxacin and Dextrose ... CILOXAN STERILE OPHTHALMIC AND OTIC SOLUTION 0.3% ... CIPROFLOXACIN LACTATE …
Velmanase alfa
Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme alpha-mannosidase, which is an enzyme responsible for breaking down complex...
Approved
Investigational
Matched Synonyms: … Recombinant Human Alpha Mannosidase …
Matched Description: … sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and ... deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. …
Matched Categories: … Recombinant Human Lysosomal alpha-Mannosidase ... Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and ... deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. …
Matched Categories: … Recombinant Human Lysosomal alpha-Mannosidase ... Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Displaying drugs 601 - 625 of 935 in total