Displaying drugs 601 - 625 of 723 in total
Rifampin
Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial that was first discovered in 1965 and clinically used in 1968. Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymerase (RNAP).
Approved
Matched Description: … in 1965 [A263753] and clinically used in 1968. ... [A263768] Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent ... Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered …
Matched Categories: … dapsone and rifampicin ... rifampicin and isoniazid ... dapsone, rifampicin and clofazimine ... rifampicin, ethambutol and isoniazid ... rifampicin, pyrazinamide and isoniazid …
Matched Products: … RICIN ... RICIN (300 MG) …
Matched Categories: … dapsone and rifampicin ... rifampicin and isoniazid ... dapsone, rifampicin and clofazimine ... rifampicin, ethambutol and isoniazid ... rifampicin, pyrazinamide and isoniazid …
Matched Products: … RICIN ... RICIN (300 MG) …
Lactulose
Lactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic encephalopathy (PSE).[FDA Label,L6199,L6202] Despite being first synthesized in 1929 , investigations regarding its possible use as a laxative for...
Approved
Matched Description: … possible use as a laxative for the treatment of chronic constipation did not occur until the 1960s and ... [L6202]
Nevertheless, although lactulose received formal FDA approval in 1977 and has since become ... List of Essential Medicines as one of the most effective and safe medicines employed in a health system …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Lactulose Hexal Konzentrat - orale Lösung ... Laevolac Lactulose Konzentrat orale Lösung ... Lactulose Genericon Konzentrat orale Lösung …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Lactulose Hexal Konzentrat - orale Lösung ... Laevolac Lactulose Konzentrat orale Lösung ... Lactulose Genericon Konzentrat orale Lösung …
4-Bromo-2,5-dimethoxyamphetamine
Experimental
Illicit
Matched Name: … 4-Bromo-2,5-dimethoxyamphetamine …
Matched Iupac: … 1-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine …
Matched Iupac: … 1-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine …
Bedaquiline
Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP...
Approved
Matched Synonyms: … 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-ol …
Matched Iupac: … (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol …
Matched Description: … The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated ... the current standard of TB treatment of anti-TB drugs for 2 months, including 2 key drugs [isoniazid] and ... [rifampin], is highly effective, the emergence of multidrug-resistant TB (MDR-TB) to [isoniazid] and …
Matched Iupac: … (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol …
Matched Description: … The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated ... the current standard of TB treatment of anti-TB drugs for 2 months, including 2 key drugs [isoniazid] and ... [rifampin], is highly effective, the emergence of multidrug-resistant TB (MDR-TB) to [isoniazid] and …
NS-3728
NS3728 is an orally active chloride channel blocker for the treatment of cancer.
Investigational
Matched Synonyms: … N-[4-bromo-2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-N'-[3,5-bis(trifluoromethyl)phenyl]urea …
Matched Iupac: … 1-[3,5-bis(trifluoromethyl)phenyl]-3-[5-bromo-2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]urea …
Matched Iupac: … 1-[3,5-bis(trifluoromethyl)phenyl]-3-[5-bromo-2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]urea …
Reynoutria multiflora root
Reynoutria multiflora root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Black-haired Mr Wu …
Beremagene geperpavec
Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB). DEB is caused by mutations in the COL7A1 gene that...
Approved
Matched Synonyms: … Dna (recombinant herpes simplex virus type 1 strain kos plasmid vector kb103 human collagen col7a1-specifying …
Matched Categories: … Cellular and Gene Therapy ... Preparations for Treatment of Wounds and Ulcers …
Matched Categories: … Cellular and Gene Therapy ... Preparations for Treatment of Wounds and Ulcers …
SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351-B.1.1.7 strains)
Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer. It is intended to elicit protection against Omicron XBB.1.5, one of the dominant circulating SARS-CoV-2 subvariants in 2023. It is produced using recombinant DNA technology in CHO cell lines and...
Approved
Matched Synonyms: … virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer – B.1.351-B.1.1.7 strains …
Matched Name: … virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351-B.1.1.7 strains …
Matched Description: … [A262551] It is produced using recombinant DNA technology in CHO cell lines and is marketed by Hipra …
Matched Name: … virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351-B.1.1.7 strains …
Matched Description: … [A262551] It is produced using recombinant DNA technology in CHO cell lines and is marketed by Hipra …
Japanese encephalitis virus strain sa 14-14-2 antigen (formaldehyde inactivated)
Approved
Matched Synonyms: … Japanese encephalitis virus strain SA 14-14-2 antigen (formaldehyde inactivated) …
Matched Name: … Japanese encephalitis virus strain sa 14-14-2 antigen (formaldehyde inactivated) …
Matched Name: … Japanese encephalitis virus strain sa 14-14-2 antigen (formaldehyde inactivated) …
Bretylium
Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation. The primary mode of action for bretylium is thought to be inhibition of voltage-gated K(+) channels. Recent evidence...
Approved
Matched Synonyms: … 2-bromo-N-ethyl-N,N-dimethylbenzenemethanaminium …
Matched Description: … tachycardia and ventricular fibrillation. ... Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is ... used in emergency medicine, cardiology, and other specialties for the acute management of ventricular …
Matched Mixtures name: … Bretylium Tosylate 0.4% and Dextrose 5% Inj ... Bretylium Tosylate 0.2% and Dextrose 5% Inj …
Matched Description: … tachycardia and ventricular fibrillation. ... Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is ... used in emergency medicine, cardiology, and other specialties for the acute management of ventricular …
Matched Mixtures name: … Bretylium Tosylate 0.4% and Dextrose 5% Inj ... Bretylium Tosylate 0.2% and Dextrose 5% Inj …
4-Bromo-2,5-dimethoxyphenethylamine
Experimental
Illicit
Matched Name: … 4-Bromo-2,5-dimethoxyphenethylamine …
Matched Iupac: … 2-(4-bromo-2,5-dimethoxyphenyl)ethan-1-amine …
Matched Iupac: … 2-(4-bromo-2,5-dimethoxyphenyl)ethan-1-amine …
3-Bromo-7-Nitroindazole
Experimental
Matched Name: … 3-Bromo-7-Nitroindazole …
Matched Iupac: … 3-bromo-7-nitro-1H-indazole …
Matched Iupac: … 3-bromo-7-nitro-1H-indazole …
Bergamot oil
Bergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Bergamot Orange Oil …
Phenytoin
Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants.[A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications such as...
Approved
Vet approved
Matched Description: … Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one ... has also been investigated for several other indications such as bipolar disorder, retina protection, and ... [A189219,A35884] Both parenteral and oral formulations of phenytoin are available on the market. …
Matched Categories: … Phenytoin and Prodrugs ... Metabolic Side Effects of Drugs and Substances ... Cytochrome P-450 CYP2B6 Inducers (strong) ... Cytochrome P-450 CYP2C8 Inducers (strong) ... Cytochrome P-450 CYP3A Inducers (strong) …
Matched Products: … BLASK® SOLUCION INYECTABLE …
Matched Categories: … Phenytoin and Prodrugs ... Metabolic Side Effects of Drugs and Substances ... Cytochrome P-450 CYP2B6 Inducers (strong) ... Cytochrome P-450 CYP2C8 Inducers (strong) ... Cytochrome P-450 CYP3A Inducers (strong) …
Matched Products: … BLASK® SOLUCION INYECTABLE …
Rifaximin
Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, meaning that the drug will not pass the gastrointestinal wall into the circulation as is common for other types of orally administered antibiotics. It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction in risk of...
Approved
Investigational
Matched Description: … It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction ... encephalopathy recurrence; as well as diarrhea-predominant irritable bowel syndrome (IBS-D) in adult women and …
Matched Categories: … Alimentary Tract and Metabolism ... Cytochrome P-450 CYP3A Inducers (strong) ... Cytochrome P-450 CYP2C19 Inducers (strong) ... Cytochrome P-450 CYP3A4 Inducers (strong) …
Matched Products: … Colidimin 200 mg/10 ml - Granulat für orale Suspension …
Matched Categories: … Alimentary Tract and Metabolism ... Cytochrome P-450 CYP3A Inducers (strong) ... Cytochrome P-450 CYP2C19 Inducers (strong) ... Cytochrome P-450 CYP3A4 Inducers (strong) …
Matched Products: … Colidimin 200 mg/10 ml - Granulat für orale Suspension …
Bromfenac
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid …
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
Matched Mixtures name: … Pred-Brom ... Pred-Brom ... Pred-Gati-Brom …
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
Matched Mixtures name: … Pred-Brom ... Pred-Brom ... Pred-Gati-Brom …
Piracetam
Piracetam is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative of the neurotransmitter γ-aminobutyric acid (GABA). However its mechanism of action differ from that of endogenous GABA. Piracetam has neuroprotective and...
Approved
Investigational
Matched Description: … Piracetam has neuroprotective and anticonvulsant properties and is reported to improve neural plasticity ... It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative ... Its efficacy is documented in cognitive disorders and dementia, vertigo, cortical myoclonus, dyslexia …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … RACETAM CAPSULE 400 mg (Orange/white) …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … RACETAM CAPSULE 400 mg (Orange/white) …
Morphine
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength...
Approved
Investigational
Matched Description: … [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk ... strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine], and …
Matched Categories: … morphine and antispasmodics …
Matched Products: … Vendal 5 mg/ml - orale Lösung ... Oramorph 10 mg - orale Lösung in Einzeldosisbehältern ... Oramorph 30 mg - orale Lösung in Einzeldosisbehältern …
Matched Categories: … morphine and antispasmodics …
Matched Products: … Vendal 5 mg/ml - orale Lösung ... Oramorph 10 mg - orale Lösung in Einzeldosisbehältern ... Oramorph 30 mg - orale Lösung in Einzeldosisbehältern …
6-bromoindirubin-3'-oxime
Experimental
Matched Synonyms: … (2Z,3E)-6'-bromo-2,3'-biindole-2',3(1H,1'H)-dione 3-oxime …
Matched Iupac: … (Z,3E)-6'-bromo-3-(hydroxyimino)-1',2'-dihydro-1H,3H-[2,3'-biindolyliden]-2'-one …
Matched Iupac: … (Z,3E)-6'-bromo-3-(hydroxyimino)-1',2'-dihydro-1H,3H-[2,3'-biindolyliden]-2'-one …
Codeine
The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease...
Approved
Illicit
Matched Description: … The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for ... Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease ... agent, and is also recommended in certain diseases with incessant coughing. …
Matched Mixtures name: … Acetaminophen and Codeine Phosphate ... Butalbital, Aspirin, Caffeine and Codeine Phosphate ... Acetaminophen and Codeine Phosphate …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... codeine and ibuprofen ... codeine and paracetamol ... codeine and acetylsalicylic acid …
Matched Products: … Linctus Codeine Blanc …
Matched Mixtures name: … Acetaminophen and Codeine Phosphate ... Butalbital, Aspirin, Caffeine and Codeine Phosphate ... Acetaminophen and Codeine Phosphate …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... codeine and ibuprofen ... codeine and paracetamol ... codeine and acetylsalicylic acid …
Matched Products: … Linctus Codeine Blanc …
Ebola Zaire vaccine (live, attenuated)
Ebola virus vaccine is a vaccine used to prevent Ebola virus disease caused by Zaire ebolavirus in adults, prevent outbreaks, and reduce the extent of the virus spreading in case of outbreaks. Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a rare but severe and often deadly disease....
Approved
Matched Synonyms: … (G) replaced with the Zaire Ebola Virus (ZEBOV) Kikwit 1995 strain surface glycoprotein (GP) ... Recombinant Vesicular Stomatitis Virus (rVSV) strain Indiana with a deletion of the VSV envelope glycoprotein …
Matched Description: … Ervebo consists of an envelope glycoprotein of the Zaire ebolavirus (Kikwit 1995 strain) fused into a ... and external bleeding. ... These may be accompanied by hypotension and respiratory, kidney and liver failure, as well as internal …
Matched Description: … Ervebo consists of an envelope glycoprotein of the Zaire ebolavirus (Kikwit 1995 strain) fused into a ... and external bleeding. ... These may be accompanied by hypotension and respiratory, kidney and liver failure, as well as internal …
Bromodiphenhydramine
Bromodiphenhydramine is an ethanolamine antihistamine with antimicrobial property. Bromodiphenhydramine is used in the control of cutaneous allergies. Ethanolamine antihistamines produce marked sedation in most patients.
Approved
Matched Synonyms: … 2-(p-bromo-α-phenylbenzyloxy)-N,N-dimethylethylamine …
Matched Mixtures name: … Diphenhydramine HCI and Zinc Acetate …
Matched Mixtures name: … Diphenhydramine HCI and Zinc Acetate …
Rineterkib
Rineterkib is an inhibitor of extracellular signal-regulated kinase (ERK) being investigated in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy of Novel Ruxolitinib Combinations in Myelofibrosis Patients).
Investigational
Matched Synonyms: … 4-(3-amino-6-((1s,3s,4s)-3-fluoro-4-hydroxycyclohexyl)-2-pyrazinyl)-n-((1s)-1-(3-bromo-5-fluorophenyl ... Benzamide, 4-(3-amino-6-((1s,3s,4s)-3-fluoro-4-hydroxycyclohexyl)-2-pyrazinyl)-n-((1s)-1-(3-bromo-5-fluorophenyl …
Matched Iupac: … 4-{3-amino-6-[(1S,3S,4S)-3-fluoro-4-hydroxycyclohexyl]pyrazin-2-yl}-N-[(1S)-1-(3-bromo-5-fluorophenyl …
Matched Description: … investigated in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and …
Matched Iupac: … 4-{3-amino-6-[(1S,3S,4S)-3-fluoro-4-hydroxycyclohexyl]pyrazin-2-yl}-N-[(1S)-1-(3-bromo-5-fluorophenyl …
Matched Description: … investigated in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and …
Iodine
Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Approved
Investigational
Matched Description: … Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may ... Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer. …
Matched Mixtures name: … Lugols Strong Iodine ... Humco Strong Iodine ... Strong Iodine Solution …
Matched Categories: … Antiseptics and Disinfectants ... Diet, Food, and Nutrition ... Herbs and Natural Products …
Matched Products: … Iodo Blanco (Iodine Tincture Decolorized) First Aid Antiseptic …
Matched Mixtures name: … Lugols Strong Iodine ... Humco Strong Iodine ... Strong Iodine Solution …
Matched Categories: … Antiseptics and Disinfectants ... Diet, Food, and Nutrition ... Herbs and Natural Products …
Matched Products: … Iodo Blanco (Iodine Tincture Decolorized) First Aid Antiseptic …
Displaying drugs 601 - 625 of 723 in total