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Displaying drugs 601 - 625 of 4239 in total
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Description: … has since become available as a generic and as a brand name product. ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and ... [A178651] And although these kinds of effects are currently included in the official prescribing information …
Matched Mixtures name: … LEVMONT 2.5/4 MG CIGNEME TABLET, 90 ADET ... LEVMONT 2.5/4 MG TOZ İÇEREN SAŞE, 90 ADET ... AIRCOMB 2,5 MG/4 MG GRANÜL İÇEREN SAŞE, 30 ADET …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Inducers ... Cytochrome P-450 CYP2A6 Substrates ... Cytochrome P-450 CYP2C8 Inhibitors …
Matched Products: … M-KAST 4 (Montelukast Chewable Tablets 4mg) ... TELKAST 4 (Montelukast Chewable Tablets 4mg) ... Montemac 4 (Montelukast Chewable Tablets 4mg) …
Silodosin is a selective antagonist of alpha(α)-1 adrenergic receptors that binds to the α1A subtype with the highest affinity. α1-adrenergic receptors regulate smooth muscle tone in the bladder neck, prostate, and prostatic urethra: the α1A subtype accounts for approximately 75% of α1-adrenoceptors in the prostate. Silodosin was first approved by...
Approved
Matched Description: … in Europe and Canada. ... highest affinity. α1-adrenergic receptors regulate smooth muscle tone in the bladder neck, prostate, and ... Silodosin is available as oral capsules with common trade names Rapaflo and Urorec. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Matched Products: … ซิโดรี 4 ... UROREC 4MG ... URIEF TABLETS 4 MG …
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Approved
Vet approved
Matched Synonyms: … 6-chloro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
Matched Iupac: … 6-chloro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Salts cas: … 7085-44-1 …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... chlorothiazide and potassium …
Stapokibart is under investigation in clinical trial NCT06424470 (Study on the Treatment of Prurigo Nodularis With Stapokibart Injection).
Investigational
Matched Synonyms: … Immunoglobulin G4 [227-proline], anti-(human interleukin 4 receptor subunit α) (human-Mus musculus monoclonal ... CM310 γ4-chain), disulfide with human-Mus musculus monoclonal CM310 κ-chain, dimer …
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Synonyms: … (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol ... 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol …
Matched Iupac: … 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol …
Matched Description: … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic ... It is also found in plants and is used pharmacologically as a sympathomimetic. ... Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Alpha-and Beta-adrenergic Agonists ... Epinephrine and similars …
Matched Products: … NOREPINEFRINA 4 MG/4ML ... Levophed Injection 4mg/4ml Vial ... ADRENOR 4 MG/4 ML IV İNFÜZYONLUK ÇÖZELTİ …
Approved
Investigational
Nutraceutical
Matched Synonyms: … Hypoxis hemerocallidea root extract …
Matched Categories: … Herbs and Natural Products ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C19 Inducers ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP3A4 Inducers …
Dalosirvat is under investigation in clinical trial NCT03742518 (A Study Evaluating the Efficacy and Safety of SM04554 Topical Solution in Male Subjects With Androgenetic Alopecia).
Investigational
Matched Synonyms: … 1-(2,3-dihydro-benzo(1,4)dioxin-6-yl)-4-phenyl-butane-1,4-dione ... 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-phenyl-butane-1,4-dione ... 1,4-butanedione, 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-phenyl- …
Matched Description: … Dalosirvat is under investigation in clinical trial NCT03742518 (A Study Evaluating the Efficacy and
Lenomorelin has been investigated for the treatment and basic science of Cancer, Alcoholism, Metabolism, Hypopituitarism, and Frailty Syndrome, among others.
Investigational
Matched Synonyms: … Ghrelin human ... Human ghrelin ... Ghrelin (human) …
Matched Description: … , Hypopituitarism, and Frailty Syndrome, among others. ... Lenomorelin has been investigated for the treatment and basic science of Cancer, Alcoholism, Metabolism …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist.[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by...
Approved
Investigational
Matched Synonyms: … 2(3H)-FURANONE, 3-ETHYLDIHYDRO-4-((1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-, (3S-CIS)- …
Matched Iupac: … (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one …
Matched Description: … intraocular pressure and glaucoma. ... [A262036] Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated …
Matched Mixtures name: … Timpilo 4 ... E-pilo-4 Oph Soln ... E-pilo 4 Ophthalmic Solution …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2A6 Inhibitors ... Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP2A6 Substrates …
Matched Products: … -carpine 4% ... Ocusert Pilo 40 ... Pilopine Hs 4% …
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... be used to treat mild to moderate essential hypertension, mild to moderate congestive heart failure, and ... to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and
Matched Salts cas: … 612548-45-5 …
Matched Mixtures name: … PERINDOPRIL DURA+4MG/1.25 ... PERINDOPRIL IND RAT 4/1.25 ... PERINDOPRIL IND RAT 4/1.25 …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... perindopril and diuretics ... perindopril and bisoprolol ... perindopril and amlodipine …
Matched Products: … HITEN 4 TABLETS 4 MG ... HITEN 4 (Perindopril tert-Butylamine Tablets 4 mg) ... COVERSYL 4 MG …
Zoledronic acid, or CGP 42'446, is a third generation, nitrogen containing bisphosphonate similar to ibandronic acid, minodronic acid, and risedronic acid. Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone.[L13712,L13715,L13721] Zoledronic acid...
Approved
Matched Description: … third generation, nitrogen containing bisphosphonate similar to [ibandronic acid], [minodronic acid], and ... [A203111] Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia ... of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone. …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... zoledronic acid, calcium and colecalciferol, sequential …
Matched Products: … ASZORA 4MG/5ML ... ZOMETA 4MG/5ML ... ZOMEKAL 4MG/5 ML …
Finotonlimab is under investigation in clinical trial NCT04560894 (SCT-I10A Plus SCT510 Versus Sorafenib as First-line Therapy for Advanced Hepatocellular Carcinoma).
Investigational
Matched Synonyms: … sct-i10a .gamma.4-chain), disulfide with human-mus musculus monoclonal sct-i10a .kappa. ... Immunoglobulin g4 (226-proline), anti-(human programmed cell death 1) (human-mus musculus monoclonal …
Investigational
Matched Synonyms: … .gamma.4-chain), disulfide with human monoclonal bi754091 .kappa. ... Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human monoclonal bi754091 …
Investigational
Matched Synonyms: … .gamma.4-chain), disulfide with human monoclonal ab122 .lambda. ... Immunoglobulin g4(231-proline), anti-(human programmed cell death protein 1) (human monoclonal ab122 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Testosterone undecanoate is the ester prodrug of testosterone and has a mid-chain fatty acid at the carbon 17β position. It was developed via fatty acid esterification of testosterone in order to achieve orally administer testosterone. There are oral and intramuscular formulations available for testosterone undecanoate: both formulations are indicated for...
Approved
Investigational
Matched Iupac: … (1S,3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta …
Matched Description: … Testosterone undecanoate is the ester prodrug of [testosterone] and has a mid-chain fatty acid at the ... of testosterone deficiency, such as decreased libido, erectile dysfunction, and loss of muscle and bone ... [A246594] There are oral and intramuscular formulations available for testosterone undecanoate: both …
Matched Categories: … Testosterone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP2B6 Substrates …
Matched Products: … Andriol Testocaps 40 mg - Kapseln ... UROMAX® 1000MG/4 ML SOLUCIÓNINYECTABLE ... Nebido 1000 mg/4 ml Injektionslösung …
Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses. Baricitinib was...
Approved
Investigational
Matched Iupac: … 2-[1-(ethanesulfonyl)-3-(4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazol-1-yl)azetidin-3-yl]acetonitrile …
Matched Description: … By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune ... European Commission (EC) in February 2017 for the treatment of rheumatoid arthritis in adults [A248395] and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … โอลูเมียนท์ (4 มก.) ... UNAMİTY 4 MG FİLM KAPLI TABLET, 7 ADET ... OLUMIANT FILM-COATED TABLET 4MG
Factor XIII (human) is a heat-treated, lyophilized concentrate of coagulation factor XIII, an endogenous enzyme responsible for the crosslinking of fibrin and an essential component of the coagulation cascade [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key...
Approved
Investigational
Matched Synonyms: … Factor XIII, human ... Human coagulation factor XIII ... Factor XIII concentrate (human) …
Matched Name: … Factor XIII (human) …
Matched Description: … Other drug products with similar structure and function to Factor XIII (human) include [DB09310], which ... Factor XIII is long (5-11 days), prophylactic therapy with the replacement of FXIII can be given every 4- ... and Drug Administration for routine prophylactic treatment and peri-operative management of surgical …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Synonyms: … HUMAN INTERFERON BETA ... Interferon beta (human) …
Matched Name: … Human interferon beta …
Matched Description: … (MS), and was initially approved by the FDA in 1992. ... [L12081] Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and ... Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Investigational
Matched Synonyms: … Recombinant human galactocerebrosidase …
Matched Name: … Recombinant human galactocerebrosidase …
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Approved
Matched Synonyms: … Antithrombin III (human) ... Antithrombin III human ... Antithrombin III,human
Matched Name: … Antithrombin III human
Matched Description: … A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Synonyms: … 6β,7β;15β,16β-Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone …
Matched Iupac: … (1R,2R,4R,10R,11S,14S,15S,16S,18S,19S)-10,14-dimethylspiro[hexacyclo[9.8.0.0^{2,4}.0^{5,10}.0^{14,19} …
Matched Description: … [L7973] Most recently, it was approved by both Health Canada and the FDA in combination with [Estetrol ... ,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to control acne and ... during the postpartum period, and this should be considered when assessing potential risks of hormonal …
Matched Mixtures name: … Drosfemine 0,02 mg/3 mg 24+4 Filmtabletten ... DROSPERA 3 MG/0.02 MG FILM KAPLI TABLET,24+4 ADET ... YAZZ 3 MG/0.02 MG FILM KAPLI TABLET, 3×(24+4) TABLET, 28 ADET …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... Genito Urinary System and Sex Hormones ... drospirenone and estetrol ... drospirenone and estrogen ... drospirenone and ethinylestradiol …
Matched Products: … Lyzbet 4 mg Filmtabletten ... SLINDA FILM-COATED TABLETS 4MG ... GYNETS® 4 MG TABLETAS RECUBIERTAS …
Experimental
Matched Name: … 1,2,5-THIADIAZOLIDIN-3-ONE-1,1-DIOXIDE
Protein S human is a vitamin K-dependent plasma glycoprotein which has antcoagulant properties . It serves as a negative feedback mechanism in the coagulation cascade.
Approved
Matched Synonyms: … Protein S (human) …
Matched Name: … Protein S human
Matched Description: … Protein S human is a vitamin K-dependent plasma glycoprotein which has antcoagulant properties [A19561 …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... Octaplex Powder and Solvent for Solution for Infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … Amylin human ... Human amylin ... Islet amyloid polypeptide (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Rumex crispus top allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Rumex crispus flower/leaf/stem extract …
Displaying drugs 601 - 625 of 4239 in total