Displaying drugs 601 - 625 of 15249 in total
Busulfan
Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought...
Approved
Investigational
Matched Iupac: … 4-(methanesulfonyloxy)butyl methanesulfonate …
Matched Description: … It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), ... Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow ... It is not a structural analog of the nitrogen mustards. …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), ... Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow ... It is not a structural analog of the nitrogen mustards. …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Turoctocog alfa pegol
Turoctocog alfa pegol is a pegylated version of turoctocog alfa. Novo Nordisk's brand name Esperoct (turoctocog alfa pegol, N8-GP) was approved by the US FDA on February 19, 2019.
Fundamentally, the N8-GP moiety is identical to turoctocog alfa, a recombinant human clotting factor VIII (rFVIII) with a truncated B-domain made...
Approved
Matched Description: … It was developed by Novo Nordisk and approved by the US FDA on October 16, 2013 [L1104]. ... 40-kDa polyethylene glycol (PEG) group to a specific _O_-glycan in the truncated B-domain of the general ... Novo Nordisk's brand name Esperoct (turoctocog alfa pegol, N8-GP) was approved by the US FDA on February …
Cinnamyl alcohol
Cinnamyl alcohol is a naturally occurring compound that is found within cinnamon. Due to the low levels found in cinnamon, cinnamyl alcohol is usually supplied as DB14184 within commercial products.
Cinnamyl alcohol has been shown to be a skin sensitizer, with a NOEL (No Effect Level) of ~4% . Sensitivity...
Approved
Experimental
Matched Description: … Cinnamyl alcohol has been shown to be a skin sensitizer, with a NOEL (No Effect Level) of ~4% [A34266 ... Due to the low levels found in cinnamon, cinnamyl alcohol is usually supplied as [DB14184] within commercial ... Cinnamyl alcohol is a naturally occurring compound that is found within cinnamon. …
Omega-3-carboxylic acids
The omega-3 carboxylic acid (OM3-CA) is a new formulation of omega-3 fatty acids that present an enhanced bioavailability in the treatment of dyslipidemia. The increased bioavailability is explained because OM3-CA is found in a form of polyunsaturated free fatty acids as opposed to other products whose form is as ethyl...
Approved
Investigational
Matched Description: … acid as the most abundant species found in a proportion of 55% and 20% respectively. ... The increased bioavailability is explained because OM3-CA is found in a form of polyunsaturated free ... [A25808] It was developed by AstraZeneca Pharmaceuticals and firstly approved by the FDA on May 05, 2014 …
Bordetella pertussis toxoid antigen (formaldehyde inactivated)
Bordetella pertussis toxoid antigen (formaldehyde inactivated) is a vaccine.
Approved
Matched Description: … Bordetella pertussis toxoid antigen (formaldehyde inactivated) is a vaccine. …
Matched Mixtures name: … -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE ... Repevax Injektionssuspension in einer Fertigspritze …
Matched Mixtures name: … -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE ... Repevax Injektionssuspension in einer Fertigspritze …
Magnesium hydroxide
Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form.
Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially...
Approved
Investigational
Matched Description: … Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable ... It can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers). ... magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially as a …
Matched Mixtures name: … Neo Tigol Tab ... One-A-day Advance Men's ... Maalox oral suspension in sachet …
Matched Mixtures name: … Neo Tigol Tab ... One-A-day Advance Men's ... Maalox oral suspension in sachet …
Propiomazine
Propiomazine, an atypical antipsychotic agent, is used to treat both negative and positive symptoms of schizophrenia, acute mania with bipolar disorder, agitation, and psychotic symptoms in dementia. Future uses may include the treatment of obsessive-compulsive disorder and severe behavioral disorders in autism. Structurally and pharmacologically similar to clozapine, propiomazine binds...
Approved
Matched Description: … positive symptoms of schizophrenia, acute mania with bipolar disorder, agitation, and psychotic symptoms in ... Future uses may include the treatment of obsessive-compulsive disorder and severe behavioral disorders in …
Influenza B virus B/Massachusetts/2/2012 BX-51B hemagglutinin antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the ... A seasonally-specific component of the influenza vaccine. …
Matched Mixtures name: … FluVaccinol Subunit Tetra Injektionssuspension in einer Fertigspritze …
Matched Mixtures name: … FluVaccinol Subunit Tetra Injektionssuspension in einer Fertigspritze …
Fenoprofen
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Approved
Pentoxyverine
Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant , and local anesthetic properties. It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists . Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors.
The...
Approved
Investigational
Withdrawn
Matched Description: … It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and ... Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic …
Matched Mixtures name: … Pancold A …
Matched Mixtures name: … Pancold A …
Sevelamer
Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Description: … Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal ... It is marketed by Genzyme under the trade name Renagel. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Ethanolamine oleate
Ethanolamine oleate is a mild sclerosing agent. It is composed of ethanolamine, a basic substance, which when combined with oleic acid forms a clear, straw to pale yellow colored, deliquescent oleate.
Approved
Matched Description: … It is composed of ethanolamine, a basic substance, which when combined with oleic acid forms a clear, ... Ethanolamine oleate is a mild sclerosing agent. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Danaparoid
Danaparoid is a low-molecular-weight heparinoid with an average molecular weight of 5500 Daltons consisting of a mixture of glycosaminoglycans . The active constituents are heparan, dermatan and DB09301 , and they are isolated from the porcine intestinal mucosa [FDA Label]. Danaparoid possesses a potent antithrombic activity that works by inhibiting...
Approved
Withdrawn
Matched Description: … on August 14, 2002, due to a shortage in drug substance by the manufacturer. ... Danaparoid possesses a potent antithrombic activity that works by inhibiting activated factor X (Factor ... of a mixture of glycosaminoglycans [A32565]. …
Ethambutol
Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA...
Approved
Matched Description: … [L31743] Ethambutol was first described in the literature in 1961. ... Ethambutol is a bacteriostatic agent indicated alongside medications such as [isoniazid], [rifampin], ... [A229048] It was developed out of a need for therapies active against isoniazid resistant strains of …
Matched Mixtures name: … ริมสตาร์ 4 - FDC ... AkuriT-4 TABLET …
Matched Mixtures name: … ริมสตาร์ 4 - FDC ... AkuriT-4 TABLET …
Citalopram
Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Iupac: … 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile …
Matched Description: … [A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 ... It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing ... [A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation …
Matched Categories: … Monoamine Oxidase A Substrates …
Matched Description: … [A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 ... It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing ... [A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation …
Matched Categories: … Monoamine Oxidase A Substrates …
Disopyramide
A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
Approved
Matched Iupac: … 4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide …
Matched Description: … membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar ... A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac …
Matched Description: … membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar ... A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac …
Verapamil
Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Description: … Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, ... arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced into therapy in ... [A188514] It is a member of the non-dihydropyridine class of calcium channel blockers, which includes …
Matched Salts cas: … 152-11-4 …
Matched Mixtures name: … TARKA® SR240/4 TABLETAS. ... VERACOMB MR 240/4 MG KAPSÜL, 28 ADET ... TARKA FORTE 240/4 FILM TABLET, 28 ADET …
Matched Salts cas: … 152-11-4 …
Matched Mixtures name: … TARKA® SR240/4 TABLETAS. ... VERACOMB MR 240/4 MG KAPSÜL, 28 ADET ... TARKA FORTE 240/4 FILM TABLET, 28 ADET …
Influenza B virus B/Brisbane/46/2015 hemagglutinin antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the ... A seasonally-specific component of the influenza vaccine. …
Loxoprofen
Loxoprofen is a propionic acid derivative non-steroidal anti-inflammatory drug. It is marketed under the trade name Loxonin in Brazil, Mexico and Japan by Sankyo, as Loxomac in India, and as Oxeno in Argentina. A transdermal preparation was approved for use in Japan in January 2006.
Approved
Matched Iupac: … 2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid …
Matched Description: … It is marketed under the trade name Loxonin in Brazil, Mexico and Japan by Sankyo, as Loxomac in India ... A transdermal preparation was approved for use in Japan in January 2006. ... Loxoprofen is a propionic acid derivative non-steroidal anti-inflammatory drug. …
Matched Description: … It is marketed under the trade name Loxonin in Brazil, Mexico and Japan by Sankyo, as Loxomac in India ... A transdermal preparation was approved for use in Japan in January 2006. ... Loxoprofen is a propionic acid derivative non-steroidal anti-inflammatory drug. …
Ramelteon
Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.
Approved
Investigational
Matched Description: … Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors ... in the suprachiasmatic nucleus (SCN). …
Influenza B virus B/Phuket/3073/2013 BVR-1B antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the ... A seasonally-specific component of the influenza vaccine. …
Matched Mixtures name: … Afluria Tetra Injektionssuspension in einer Fertigspritze …
Matched Mixtures name: … Afluria Tetra Injektionssuspension in einer Fertigspritze …
Ecamsule
Ecamsule is an organic compound which is added to many sunscreens to filter out UVA rays. It is a benzylidene camphor derivative, many of which are known for their excellent photostability. Ecamsule has been approved for use in the U.S. since 2006, but only at a specific concentration and only...
Approved
Matched Iupac: … {3-[(4-{[7,7-dimethyl-3-oxo-4-(sulfomethyl)bicyclo[2.2.1]heptan-2-ylidene]methyl}phenyl)methylidene]- …
Matched Description: … in a few products manufactured by L'Oreal. ... Ecamsule has been approved for use in the U.S. since 2006, but only at a specific concentration and only ... The company got approval for those products through a new drug application process. …
Matched Mixtures name: … Anthelios XL Melt-IN Cream …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … in a few products manufactured by L'Oreal. ... Ecamsule has been approved for use in the U.S. since 2006, but only at a specific concentration and only ... The company got approval for those products through a new drug application process. …
Matched Mixtures name: … Anthelios XL Melt-IN Cream …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Phenyl salicylate
Phenyl salicylate is a 2-hydroxybenzoic acid phenyl ester. It is utilized in some manufacturing processes of polymers, lacquers, adhesives, waxes, as well as polishes. It is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing salicylate (found in DB00945 ). Phenyl salicylate may...
Approved
Matched Description: … It is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing ... Phenyl salicylate is used as a food additive in the USA [L2479]. ... aromatic units linked by an ester bond (depside), or a compound containing the depsidone structure ( …
Matched Mixtures name: … ยาเม็ดตกเบ็ด 4. …
Matched Mixtures name: … ยาเม็ดตกเบ็ด 4. …
Cinoxate
Approved
Matched Iupac: … 2-ethoxyethyl (2E)-3-(4-methoxyphenyl)prop-2-enoate …
Matched Mixtures name: … Le Stick A Levres Onybel …
Matched Mixtures name: … Le Stick A Levres Onybel …
Perflutren
Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the...
Approved
Matched Description: … Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated ... level of contrast visible in the resulting ultrasound image. ... The difference in density between the gas-filled bubbles and the blood around them creates an increased …
Matched Mixtures name: … Optison Perflutren Protein-Type A Microspheres …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Mixtures name: … Optison Perflutren Protein-Type A Microspheres …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 601 - 625 of 15249 in total