Displaying drugs 6376 - 6400 of 8039 in total
Phosphorus P-32
Phosphorus P-32 is a radioactive isotope of phosphorus with beta particle-emitting radiocytotoxic activity. Emitted by phosphorus P32, beta particles directly damage cellular DNA and, by ionizing intracellular water to produce several types of cytotoxic free radicals and superoxides, indirectly damage intracellular biological macromolecules, resulting in tumor cell death.
Experimental
Matched Description: … Phosphorus P-32 is a radioactive isotope of phosphorus with beta particle-emitting radiocytotoxic activity ... particles directly damage cellular DNA and, by ionizing intracellular water to produce several types of …
Avasopasem manganese
Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide dismutase (SOD) being investigated for the reduction of radiation-induced severe oral mucositis.[L27246, L27256] This drug has potential application for radiation-induced esophagitis and oral mucositis, in addition to being currently tested against COVID-19.
Investigational
Matched Description: … Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide ... dismutase (SOD) being investigated for the reduction of radiation-induced severe oral mucositis. …
ZYCOV-D
The ZYCOV-D vaccine candidate was developed by Cadila Healthcare Ltd. based in India . The vaccine was developed using a DNA vaccine platform with a non-replicating and non-integrating plasmid carrying the gene of interest . Once the plasmid DNA is introduced into host cells and the viral protein is translated,...
Investigational
Matched Description: … As of August, 2020 the candidate is in Phase II clinical trials[A219758]. ... using a DNA vaccine platform with a non-replicating and non-integrating plasmid carrying the gene of ... is translated, it elicits a strong immune response, stimulating the humoral and cellular components of …
Xylazine
Xylazine is a clonidine analog used as a non-opioid tranquilizer in veterinary medicine and as an emetic, especially in cats.[A9095,L42675,A251420] It acts as an agonist at α2 adrenoceptors; however, its affinity is lower than the one reported for other α2 adrenergic receptor agonists such as detomidine and medetomidine. Xylazine is...
Vet approved
Matched Description: … [A9096] The use of xylazine can lead to hypotension and bradycardia[A9092,A9093], and when combined with ... [L42680] The intentional and unintentional use of xylazine is a cause for concern due to its side effects ... adulterant and combined with opioids and recreational drugs; however, it has no antidote, and the use of …
VPM1002
The bacille Calmette-Guérin (BCG) vaccine protects against severe extrapulmonary forms of tuberculosis (TB) but does not adequately protect against pulmonary TB -- the most prevalent form of TB. This recombinant BCG, VPM1002, has been created in response and investigated for preventing pulmonary TB in newborns and TB recurrence in adults...
Investigational
Matched Description: … (TB) but does not adequately protect against pulmonary TB -- the most prevalent form of TB. ... The bacille Calmette-Guérin (BCG) vaccine protects against severe extrapulmonary forms of tuberculosis ... BCG Prague as it has a better safety profile than some other BCG versions due to the lack of the RD2 …
Acepromazine
Acepromazine is one of the phenothiazine derivative psychotropic drugs, used little in humans, however frequently in animals as a sedative and antiemetic.
Experimental
Vet approved
Matched Description: … Acepromazine is one of the phenothiazine derivative psychotropic drugs, used little in humans, however …
Phenacetin
Phenacetin was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy (damage to or disease of the kidney).
Withdrawn
Matched Description: … withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy (damage to or disease of …
MAHDL01
MAHDL01 is a pharmaceutical combination of whole plants, which is used to increase the HDL/LDL ratio that improves overall cardiovascular health.
Investigational
Matched Description: … MAHDL01 is a pharmaceutical combination of whole plants, which is used to increase the HDL/LDL ratio …
Dactolisib
Dactolisib has been used in trials studying the treatment of Cancer, Solid Tumor, Renal Cancer, Breast Cancer, and Cowden Syndrome, among others.
Investigational
Matched Description: … Dactolisib has been used in trials studying the treatment of Cancer, Solid Tumor, Renal Cancer, Breast …
Adavosertib
MK-1775 has been used in trials studying the treatment of LYMPHOMA, Neoplasms, Ovarian Cancer, Tongue Carcinoma, and Adult Glioblastoma, among others.
Investigational
Matched Description: … MK-1775 has been used in trials studying the treatment of LYMPHOMA, Neoplasms, Ovarian Cancer, Tongue …
Uprosertib
Uprosertib has been used in trials studying the treatment of Cancer, Melanoma, Solid Tumours, Cervical Cancer, and HER2/Neu Negative, among others.
Investigational
Matched Description: … Uprosertib has been used in trials studying the treatment of Cancer, Melanoma, Solid Tumours, Cervical …
Thymosin beta-4
Thymosin Beta 4 has been investigated for the treatment of STEMI, Dry Eye, Diabetes, Pressure Ulcers, and Dry Eye Syndrome, among others.
Investigational
Matched Description: … Thymosin Beta 4 has been investigated for the treatment of STEMI, Dry Eye, Diabetes, Pressure Ulcers, …
Simtuzumab
Simtuzumab has been used in trials studying the treatment and basic science of Myelofibrosis, Pancreatic Cancer, Colorectal Cancer, and Idiopathic Pulmonary Fibrosis.
Investigational
Matched Description: … Simtuzumab has been used in trials studying the treatment and basic science of Myelofibrosis, Pancreatic …
LY-3023414
LY3023414 has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, BREAST CANCER, and Advanced Cancer, among others.
Investigational
Matched Description: … LY3023414 has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, BREAST …
TAK-733
TAK-733 has been used in trials studying the treatment of Advanced Metastatic Melanoma, Advanced Nonhematologic Malignancies, and Advanced Non-hematologic Malignancies.
Investigational
Matched Description: … TAK-733 has been used in trials studying the treatment of Advanced Metastatic Melanoma, Advanced Nonhematologic …
Merestinib
Merestinib has been used in trials studying the treatment of Cancer, Solid Tumor, Advanced cancer, ColoRectal Cancer, and Metastatic Cancer, among others.
Investigational
Matched Description: … Merestinib has been used in trials studying the treatment of Cancer, Solid Tumor, Advanced cancer, ColoRectal …
Samarium
Samarium has been used in trials studying the treatment and prevention of Pain, Cancer, Metastasis, Prostate Cancer, and Metastatic Osteosarcoma, among others.
Investigational
Matched Description: … Samarium has been used in trials studying the treatment and prevention of Pain, Cancer, Metastasis, Prostate …
Gemigliptin
Gemigliptin is under investigation in Type 2 Diabetes Mellitus. Gemigliptin has been investigated for the treatment of Cancer and Cisplatin Adverse Reaction.
Investigational
Matched Description: … Gemigliptin has been investigated for the treatment of Cancer and Cisplatin Adverse Reaction. …
Fasiglifam
Fasiglifam has been used in trials studying the treatment of Chronic Kidney Disease, Type 2 Diabetes Mellitus, and Diabetes Mellitus, Type 2.
Investigational
Matched Description: … Fasiglifam has been used in trials studying the treatment of Chronic Kidney Disease, Type 2 Diabetes …
Alagebrium
Alagebrium has been investigated for the treatment and prevention of Aging, Heart Failure, Physical Activity, Diabetic Nephropathy, and Cardiovascular Disease, among others.
Investigational
Matched Description: … Alagebrium has been investigated for the treatment and prevention of Aging, Heart Failure, Physical Activity …
Naptumomab estafenatox
Naptumomab Estafenatox has been used in trials studying the treatment of Pancreatic Cancer, Renal Cell Carcinoma, and Non-Small-Cell Lung Carcinoma.
Investigational
Matched Description: … Naptumomab Estafenatox has been used in trials studying the treatment of Pancreatic Cancer, Renal Cell …
Melarsoprol
Melarsoprol is under investigation in clinical trial NCT00330148 (Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis).
Investigational
Matched Description: … Melarsoprol is under investigation in clinical trial NCT00330148 (Randomized Clinical Trial of Three …
Ombrabulin
Ombrabulin has been used in trials studying the treatment of Sarcoma, Neoplasms, Solid Tumor, Neoplasms, Malignant, and Advanced Solid Tumors, among others.
Investigational
Matched Description: … Ombrabulin has been used in trials studying the treatment of Sarcoma, Neoplasms, Solid Tumor, Neoplasms …
Samarium Sm-153
Samarium 153 has been used in trials studying the supportive care of Pain, Lung Cancer, Breast Cancer, Prostate Cancer, and Metastatic Cancer.
Investigational
Matched Description: … Samarium 153 has been used in trials studying the supportive care of Pain, Lung Cancer, Breast Cancer …
Prifinium
Prifinium is an antimuscarinic agent with antispasmodic and antiemetic properties. It may be useful for the treatment of irritable bowel syndrome .
Experimental
Matched Description: … It may be useful for the treatment of irritable bowel syndrome [A175027]. …
Displaying drugs 6376 - 6400 of 8039 in total