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Displaying drugs 626 - 650 of 2920 in total
Experimental
Matched Synonyms: … Isopentenyl adenine ... N6-(3-methylbut-2-enyl)adenine ... N6-(delta2-Isopentenyl)-adenine
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Approved
Investigational
Vet approved
Matched Description: … combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and
Matched Salts name: … Sulfadiazine sodium
Matched Categories: … sulfadiazine and tetroxoprim ... Sulfonamides and trimethoprim ... sulfadiazine and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Sulfadiazine Sodium
Toremifene is a selective estrogen receptor modulator (SERM) and a nonsteroidal antiestrogen used to treat estrogen receptor positive breast cancer. Like tamoxifen, toremifene is part of the first-generation triphenylethylene derivative chemical class of SERMs. Toremifene possesses tissue-specific actions: it has estrogenic (agonist) activity on the cardiovascular system and on bone...
Approved
Investigational
Matched Description: … Toremifene is a selective estrogen receptor modulator (SERM) and a nonsteroidal antiestrogen used to ... possesses tissue-specific actions: it has estrogenic (agonist) activity on the cardiovascular system and ... on bone tissue and it has weak estrogenic effects on uterine tissue, however, it also has antiestrogenic …
Matched Salts name: … Toremifene citrate
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Toremifene Citrate
Experimental
Matched Synonyms: … β-glycerophosphoric acid ... beta-Glycerophosphoric acid ... 1,3-Hydroxy-2-propyl dihydrogen phosphate
Matched Name: … Glycerol 2-phosphate
Matched Iupac: … [(1,3-dihydroxypropan-2-yl)oxy]phosphonic acid
Matched Categories: … Sugar Phosphates
Experimental
Matched Synonyms: … D-Fructose 6-phosphoric acid ... D-Fructose 6-phosphate ... keto-D-fructose 6-phosphate
Matched Name: … Fructose-6-phosphate
Matched Iupac: … {[(2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl]oxy}phosphonic acid
Matched Categories: … Sugar Phosphates
An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Approved
Matched Synonyms: … Carboxyphosphonic acid ... Phosphonoformic acid ... Phosphonomethanoic acid
Matched Iupac: … phosphonoformic acid
Matched Description: … Foscarnet also shows activity against human herpes viruses and HIV. …
Matched Salts name: … Foscarnet sodium
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Phosphonic Acid Derivatives ... Nucleic Acid Synthesis Inhibitors …
Matched Products: … Foscarnet Sodium
Aluminum chloride is a chemical compound with the chemical formula AlCl3. When contaminated with iron chloride, it often displays a yellow color compared to the white pure compound. It is used in various chemical applications as a Lewis base, with anhydrous aluminium trichloride being the most commonly used Lewis acid....
Approved
Investigational
Matched Synonyms: … Aluminium chloride
Matched Name: … Aluminum chloride
Matched Description: … the most commonly used Lewis acid. ... It is used in various chemical applications as a Lewis base, with anhydrous aluminium trichloride being ... Aluminum chloride is a chemical compound with the chemical formula AlCl3. …
Matched Salts name: … Aluminium chloride hexahydrate …
Matched Categories: … Astringents and Deodorants ... Chlorides ... Chlorine Compounds ... aluminium chloride
An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
Approved
Investigational
Vet approved
Matched Description: … An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations …
Matched Salts name: … Diethylcarbamazine citrate
Matched Categories: … Piperazine and Derivatives ... Antiparasitic Products, Insecticides and Repellents ... Acids, Acyclic ... Carboxylic Acids
Matched Products: … DIETHYLCARBAMAZINE CITRATE
Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It...
Approved
Matched Iupac: … (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
Matched Description: … levels and prevent cardiovascular disease. ... Fluvastatin is a racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. ... Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol …
Matched Salts name: … Fluvastatin sodium
Matched Categories: … Fatty Acids ... Heptanoic Acids
Matched Products: … Fluvastatin Sodium ... Fluvastatin Sodium ER …
Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched Description: … treat malaria until the development of newer antimalarials such as [pyrimethamine], [artemisinin], and ... of a number of other conditions including HIV, systemic lupus erythematosus, and rheumatoid arthritis ... [A191787] Chloroquine and its derivative [hydroxychloroquine] have since been repurposed for the treatment …
Matched Salts name: … Chloroquine phosphate
Matched Categories: … chloroquine and proguanil ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … Chloroquine Phosphate ... Chloroquine phosphate ... CHLOROQUINE PHOSPHATE
Experimental
Matched Synonyms: … Ferric citrate fe-59 …
Matched Name: … Ferric (59Fe) citrate
Matched Categories: … ferric (59Fe) citrate
Investigational
Matched Synonyms: … 9-(2-(phosphonomethoxy)ethyl)adenine ... 9-(2-phosphonylmethoxyethyl)adenine
Matched Iupac: … {[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}phosphonic acid
Matched Categories: … Nucleic Acid Synthesis Inhibitors …
Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Description: … allergic symptoms and disorders,[A231204] including urticaria, mastocytosis, and food allergy. ... Ketotifen is a benzocycloheptathiophene derivative[A231204] with potent antihistaminic and mast cell ... It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Up and Up Eye Itch Relief …
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Approved
Investigational
Matched Salts name: … Ganciclovir sodium
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … Ganciclovir Sodium ... GANCICLOVIR SODIUM FOR INJECTION …
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Synonyms: … 4-amino-10-methylfolic acid ... 4-amino-N(10)-methylpteroylglutamic acid ... N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Matched Iupac: … -[(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid
Matched Description: … inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and ... Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and
Matched Salts name: … Methotrexate sodium
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists ... Nucleic Acid Synthesis Inhibitors …
Matched Products: … Methotrexate Sodium ... Ratio-methotrexate Sodium ... Methotrexate Sodium Inj 20mg …
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … 2-amino-3-(4-bromobenzoyl)benzeneacetic acid ... [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
Matched Salts name: … Bromfenac sodium
Matched Products: … Bromfenac Sodium
Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body. It is on the World Health Organization Model List of Essential Medicines. Edetate calcium disodium was granted FDA approval on 16 July 1953.
Approved
Matched Synonyms: … Edetic acid calcium disodium salt ... Edetate calcium disodium (anhydrous) …
Matched Name: … Edetate calcium disodium anhydrous
Matched Description: … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores …
Matched Categories: … Diet, Food, and Nutrition ... Acids, Acyclic ... Carboxylic Acids
Matched Products: … Calcium Edetate de Sodium
Investigational
Matched Synonyms: … RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB) VARIANT III (EGFRVIII)) AND
Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis).
Investigational
Matched Synonyms: … immunoglobulin G1-kappa, anti-[Homo sapiens KLB (klotho beta, b-Klotho)] and anti-[Homo sapiens FGFR1 …
Matched Description: … Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and
Experimental
Matched Synonyms: … Deoxyuridylic acid ... Deoxyuridine 5'-phosphate ... 2'-Deoxyuridine 5'-phosphate
Matched Iupac: … {[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic acid
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Strontium chloride (Sr-89), initially FDA-approved in 1993, is used as a paliative therapeutic option to help relieve the pain from bone metastases. Strontium chloride is mainly used in cases of metastatic castrate-resistant prostate cancer. Bone metastases is a common and severe complication presented in advanced stages of the disease. It...
Approved
Investigational
Matched Synonyms: … Strontium (89Sr) chloride ... Strontium-89 chloride ... Strontium chloride Sr 89 …
Matched Name: … Strontium chloride Sr-89 …
Matched Description: … lung, bladder and thyroid. ... [A31264] Bone metastases is a common and severe complication presented in advanced stages of the disease ... It is usually presented mainly in patients with prostatic and breast cancer, as well as in cancer of …
Matched Categories: … strontium (89Sr) chloride
Matched Products: … STRONTIUM CHLORIDE Sr-89 …
Approved
Matched Synonyms: … Undecoylium chloride-iodine …
Matched Name: … Undecoylium chloride iodine complex …
Matched Iupac: … 1-({[2-(propanoyloxy)ethyl]carbamoyl}methyl)pyridin-1-ium chloride
Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Iupac: … carbamoyl}-3-[(2R)-3-carbamoyl-2-[(2S)-2-decanamido-3-(1H-indol-3-yl)propanamido]propanamido]propanoic acid
Matched Description: … and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked ring and the N-terminal ... -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE). ... with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Daptomycin in Sodium Chloride
Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Description: … concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and ... [A232294, A232299, L32739] However, tobramycin can also be administered intravenously and topically to ... L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and
Matched Mixtures name: … Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone …
Matched Products: … Tobramycin in Sodium Chloride
5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
Experimental
Matched Synonyms: … 5'-Thymidylic acid ... Thymidylic acid ... Thymidine 5'-phosphate
Matched Iupac: … 5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acid
Matched Description: … 5-Thymidylic acid. ... A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Displaying drugs 626 - 650 of 2920 in total