Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Did you mean glycol and hyaluronate sodium and para collagen?
Displaying drugs 626 - 650 of 14457 in total

Etidronic acid

Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Description: … Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and ... generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and …
Matched Categories: … etidronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization …

Lomustine

An alkylating agent of value against both hematologic malignancies and solid tumors.
Approved
Investigational
Matched Description: … An alkylating agent of value against both hematologic malignancies and solid tumors. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Telbivudine

Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
Approved
Investigational
Matched Description: … Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects …
Matched Categories: … Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …

Telavancin

Telavancin is a semi-synthetic derivative of vanocymycin that has bactericidal activity against Methicillin-resistant Staphylococcus aureus (MRSA) and other gram-positive bacteria. MRSA is an important pathogen capable of causing hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and skin and subcutaneous tissue infections among others.
Approved
Matched Description: … skin and subcutaneous tissue infections among others. ... vanocymycin that has bactericidal activity against Methicillin-resistant Staphylococcus aureus (MRSA) and ... pathogen capable of causing hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Asunaprevir

Asunaprevir, also named BMS-650032, is a potent hepatitis C virus (HCV) NS3 protease inhibitor. It has been shown to have a very high efficacy in dual-combination regimens with daclatasvir in patients chronically infected with HCV genotype 1b. It was developed by Bristol-Myers Squibb Canada and approved by Health Canada on...
Approved
Investigational
Withdrawn
Matched Description: … [A32528] It was developed by Bristol-Myers Squibb Canada and approved by Health Canada on April 22, 2016 …
Matched Categories: … daclatasvir, asunaprevir and beclabuvir …

Sacrosidase

Sacrosidase is a liquid enzyme preparation from S.cerevisiae used for the treatment of congenital sucrose-isomaltase deficiency (CSID). People with CSID have variable amounts of sucrose-isomaltase enzyme activity and therefore have issues metabolizing dietary disaccharide sucrose causing chronic or intermittent watery diarrhea in infants and children. Treatment options for these patients...
Approved
Matched Description: … People with CSID have variable amounts of sucrose-isomaltase enzyme activity and therefore have issues ... Treatment options for these patients are limited and usually consists of a lifelong sucrose-free diet ... metabolizing dietary disaccharide sucrose causing chronic or intermittent watery diarrhea in infants and …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Foslevodopa

Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and Change in Disease Activity of 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants With Advanced Parkinson's Disease).
Approved
Investigational
Matched Description: … Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and …
Matched Categories: … Dopa and Dopa Derivatives ... foslevodopa and decarboxylase inhibitor …

Vestronidase alfa

Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Description: … spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble ... The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid ... patients may experience developmental delay and progressive intellectual disability [FDA Label]. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Insulin icodec

Insulin icodec is an ultra long-acting basal insulin analogue.
Approved
Investigational
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Tibolone

Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha . Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic...
Approved
Investigational
Matched Description: … produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic and ... Tibolone is approved in 90 countries to manage menopausal symptoms and in 45 countries to prevent the ... been used in Europe for almost 2 decades, primarily for the prevention of postmenopausal osteoporosis and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Estrogens, Antiestrogens, and Estrogen Agonist-Antagonists …

Diethyltoluamide

Diethyltoluamide (DEET) is the common active ingredient in many insect repellent products. It is widely used to repel biting pests such as mosquitoes and ticks. Every year, DEET formulations are used to protect populations from mosquito-borne illnesses like West Nile Virus, the Zika virus, malaria, and/or tick-borne illnesses like Lyme...
Approved
Matched Description: … It is widely used to repel biting pests such as mosquitoes and ticks. ... /or tick-borne illnesses like Lyme disease and Rocky Mountain spotted fever. ... to protect populations from mosquito-borne illnesses like West Nile Virus, the Zika virus, malaria, and …
Matched Categories: … Insecticides and Repellents ... Benzamides and benzamide derivatives ... Scabicides, Insecticides and Repellents ... Antiparasitic Products, Insecticides and Repellents …

Mangafodipir

Mangafodipir is a contrast agent used as a diagnostic tool administered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver and pancreas. This drug is made up of paramagnetic manganese (II) ions combined with the chelating agent fodipir (dipyridoxyl diphosphate, DPDP). Manganese absorption into the tissues that...
Approved
Investigational
Withdrawn
Matched Description: … tool administered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver and ... Enhanced contrast by mangafodipir improves visualization and detection of lesions of the liver formed ... Teslascan has been removed from the Drug Product List by FDA in 2003, and withdrawn from the European …
Matched Categories: … Enzymes and Coenzymes …

Idursulfase

Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various...
Approved
Matched Description: … -sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Polyestradiol phosphate

Polymeric phosphoric acid ester of estradiol.
Approved
Matched Categories: … Hormones and Related Agents ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Patisiran

Parisiran is a first in class short interfering RNA for the treatment of patients with polyneuropathy caused by hereditary transthyretin-mediated amyloidosis . It is marketed as Onpattro which is formulated as patisiran within a liposome envelope for better delivery to the liver, where transthyretin is produced. The approval for Onpattro...
Approved
Investigational
Matched Description: … Onpattro has been granted Fast Track, Priority Review and Breakthrough Therapy, and Orphan Drug designations …
Matched Salts name: … Patisiran sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Amivantamab

Amivantamab, also known as JNJ-61186372, is an anti-EGFR-MET bispecific antibody, derived from Chinese hamster ovary cells, approved for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion mutations, as detected by an FDA-approved test, whose...
Approved
Investigational
Matched Description: … FDA approval on 21 May 2021,[L34193] followed by the approval by the EMA on 9 December 2021 [L41474] and ... [A235103,L34193] Patients with NSCLC often develop resistance to drugs that target EGFR and MET individually ... Patients with NSCLC with exon 20 insertion mutations in EGFR do not respond to tyrosine kinase inhibitors, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Nedosiran

Nedosiran is an RNA interference targeting hepatic lactate dehydrogenase, the enzyme responsible for the conversion of glyoxylate to oxalate. Oxalate, particularly calcium oxalate, precipitation is the main cause of kidney stones formation; therefore, blocking the production of oxalate can help alleviate renal symptoms. Nedosiran was approved by the FDA on...
Approved
Investigational
Matched Description: … older and adults with primary hyperoxaluria type 1 (PH1) and relatively preserved kidney function. ... sup>, 2023, under the brand name RIVFLOZA to lower urinary oxalate levels in children 9 years of age and ... This approval is based on the favorable results from the pivotal phase 2 PHYOXTM2 and interim …
Matched Salts name: … Nedosiran sodium …

Icosapent

Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
Approved
Nutraceutical
Matched Description: … It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. ... inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families. ... lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and …
Matched Salts name: … Icosapent sodium …

Somapacitan

Somapacitan, also known as NNC0195-0092, is a growth hormone analog indicated to treat adults with growth hormone deficiency.[A219126,L15661] This human growth hormone analog differs by the creation of an albumin binding site, and prolonging the effect so that it requires weekly dosing rather than daily. Somapacitan was granted FDA approval...
Approved
Investigational
Matched Description: … A219126,L15661] This human growth hormone analog differs by the creation of an albumin binding site, and …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Somatropin and Somatropin Agonists ... Anterior Pituitary Lobe Hormones and Analogues …

Bazedoxifene

Bazedoxifene is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. It is approved in the...
Approved
Investigational
Matched Description: … It is approved in the European Union (marketed in Italy and Spain) and Japan as monotherapy. ... In 2013, the combination product containing conjugated estrogens and bazedoxifene was approved by the …
Matched Categories: … Genito Urinary System and Sex Hormones ... conjugated estrogens and bazedoxifene ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Pixantrone

Pixantrone is an aza-anthracenedione and DNA intercalator which inhibits topoisomerase II. It is similar in structure to anthracyclines such as mitoxantrone, but exerts fewer toxic effects on cardiac tissue. [2] The lower cardio-toxic effects of pixantrone may be explained, in part, by its redox inactivity [3]. Pixantrone does not bind...
Approved
Investigational
Matched Description: … Pixantrone is an aza-anthracenedione and DNA intercalator which inhibits topoisomerase II. ... Pixantrone does not bind iron and promotes the formation of reactive oxygen species to a lesser degree ... that it resulted in significantly higher complete response rate and progression free survival in comparison …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …

Catumaxomab

Catumaxumab is a trifunctional monoclonal antibody developed for use in cancer treatment. It has affinity for T-cells, accessory immune cells, and cancer cells. Catumaxumab was initially authorized for market by the European Medicines Agency in April 2009 for the treatment of malignant ascites . Its market authorization was withdrawn in...
Approved
Investigational
Withdrawn
Matched Description: … It has affinity for T-cells, accessory immune cells, and cancer cells. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Eptotermin alfa

A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.
Approved
Investigational
Withdrawn
Matched Description: … It is both a potent osteogenic factor and a specific regulator of nephrogenesis. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Drugs Affecting Bone Structure and Mineralization …

Dibotermin alfa

Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant Chinese Hamster Ovary (CHO) cell line [FDA Label]. It is implanted in patients undergoing bone surgeries or those with fractures. BMPs are subfamily of the transforming growth factor-β (TGF-β) superfamily that have different actions on the...
Approved
Investigational
Matched Description: … In 2004, it was approved by the FDA and is marketed as Infuse. ... critical role in the differentiation of osteoprogenitor cells into osteoblasts, thus promoting bone and ... at the site of implantation, dibotermin alfa accelerates the healing of open tibial shaft fractures and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Drugs Affecting Bone Structure and Mineralization …

Dasiglucagon

Dasiglucagon is a glucagon analog that acts to increase blood sugar levels. It consists of 29 amino acids similar to endogenous glucagon; however, it contains seven substituted amino acids for improved physical and chemical stability in its drug formulation. In March 2021, the FDA approved dasiglucagon to treat severe hypoglycemia...
Approved
Investigational
Matched Description: … similar to endogenous glucagon; however, it contains seven substituted amino acids for improved physical and ... L39195] In March 2021, the FDA approved dasiglucagon to treat severe hypoglycemia in patients six years and ... Hypoglycemia is a common side effect of antidiabetic treatments, most notably insulin and sulfonylureas …
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Displaying drugs 626 - 650 of 14457 in total