Displaying drugs 6626 - 6650 of 8235 in total
WU-CART-007
WU-CART-007 consists of allogeneic, fratricide-resistant genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7.
Investigational
Matched Description: … WU-CART-007 consists of allogeneic, fratricide-resistant genetically modified T cells transduced with …
Ozekibart
Ozekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5). It is being investigated for the treatment of chondrosarcoma.
Investigational
Matched Description: … It is being investigated for the treatment of chondrosarcoma. …
Tidutamab
Tidutamab is under investigation in clinical trial NCT04590781 (Safety and Efficacy of Xmab18087 ± Pembrolizumab in Advanced Merkel Cell Carcinoma or Extensive-stage Small Cell Lung Cancer).
Investigational
Matched Description: … Tidutamab is under investigation in clinical trial NCT04590781 (Safety and Efficacy of Xmab18087 ± Pembrolizumab …
Burfiralimab
Burfiralimab is under investigation in clinical trial NCT06306339 (A Study to Assess the Efficacy and Safety of Burfiralimab (Hzvsf-v13) and DMRD (Disease-modifying Antirheumatic Drug)).
Investigational
Matched Description: … Burfiralimab is under investigation in clinical trial NCT06306339 (A Study to Assess the Efficacy and Safety of …
Mapatumumab
Mapatumumab is under investigation in clinical trial NCT00094848 (Study of TRM-1 (TRAIL-R1 Monoclonal Antibody) in Subjects With Relapsed or Refractory Non-hodgkin's Lymphoma (NHL)).
Investigational
Matched Description: … Mapatumumab is under investigation in clinical trial NCT00094848 (Study of TRM-1 (TRAIL-R1 Monoclonal …
Danicamtiv
Danicamtiv is under investigation in clinical trial NCT04572893 (Exploratory Study of Danicamtiv in Patients With Primary Dilated Cardiomyopathy (DCM) Due to Genetic Variants or Other Causalities).
Investigational
Matched Description: … Danicamtiv is under investigation in clinical trial NCT04572893 (Exploratory Study of Danicamtiv in Patients …
Tobemstomig
Tobemstomig is under investigation in clinical trial NCT05908786 (A Study Evaluating the Efficacy and Safety of Neoadjuvant Immunotherapy Combinations in Patients With Surgically Resectable Hepatocellular Carcinoma).
Investigational
Matched Description: … Tobemstomig is under investigation in clinical trial NCT05908786 (A Study Evaluating the Efficacy and Safety of …
VPM1002
The bacille Calmette-Guérin (BCG) vaccine protects against severe extrapulmonary forms of tuberculosis (TB) but does not adequately protect against pulmonary TB -- the most prevalent form of TB. This recombinant BCG, VPM1002, has been created in response and investigated for preventing pulmonary TB in newborns and TB recurrence in adults...
Investigational
Matched Description: … (TB) but does not adequately protect against pulmonary TB -- the most prevalent form of TB. ... The bacille Calmette-Guérin (BCG) vaccine protects against severe extrapulmonary forms of tuberculosis ... BCG Prague as it has a better safety profile than some other BCG versions due to the lack of the RD2 …
Putrescine
Putrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. Putrescine is a solid. This compound belongs to the polyamines. These are compounds containing more than one amine group. Known drug targets of putrescine include putrescine-binding periplasmic protein, ornithine decarboxylase, and S-adenosylmethionine decarboxylase proenzyme.
Experimental
Matched Description: … Putrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine ... Known drug targets of putrescine include putrescine-binding periplasmic protein, ornithine decarboxylase …
MK-0354
MK-0354, is an orally administered drug candidate under development by Merck for the treatment of atherosclerosis and related disorders. It targets G protein-coupled receptor, or GPCR, that have the potential to regulate plasma lipid profiles, including HDL, or the good cholesterol, similar to the therapeutic action of niacin.
Investigational
Matched Description: … MK-0354, is an orally administered drug candidate under development by Merck for the treatment of atherosclerosis ... regulate plasma lipid profiles, including HDL, or the good cholesterol, similar to the therapeutic action of …
PX-478
PX-478 is a small molecule inhibitor of hypoxia inducible factor (HIF)-1 alpha currently in a clinical trial in patients with advanced metastatic cancer and lymphoma. PX-478 was effective in models of both non-small cell lung cancer
and small cell lung cancer that express HIF-1 alpha.
Investigational
Matched Description: … PX-478 is a small molecule inhibitor of hypoxia inducible factor (HIF)-1 alpha currently in a clinical ... PX-478 was effective in models of both non-small cell lung cancer
and small cell lung cancer that express …
3,4-Methylenedioxy-N-isopropylamphetamine
MDI-P has demonstrated potent anti-HIV activity. MDI-P has been shown to be effective in killing HIV in cell culture. HIV is the virus that causes acquired immune deficiency syndrome (AIDS). MDI-P is also a potential therapeutic agent for the treatment of the symptoms of cystic fibrosis ("CF").
Investigational
Matched Description: … MDI-P is also a potential therapeutic agent for the treatment of the symptoms of cystic fibrosis ("CF …
Quaternium-18
Quaternium-18 is a mixture of quaternary ammonium chloride salts. Quaternium-18 Hectorite and Bentonite are the reaction products of Quaternium-18 with clays. These compounds are poorly absorbed through the skin. Acute oral and percutaneous toxicity tests in animals indicate that they exhibit little or no systemic toxic effects.
Experimental
Matched Description: … Quaternium-18 is a mixture of quaternary ammonium chloride salts. ... Quaternium-18 Hectorite and Bentonite are the reaction products of Quaternium-18 with clays. …
Alfaxalone
Alfaxalone, also known as alphaxalone or alphaxolone, is a neuroactive steroid and general anaesthetic. It is used in veterinary practice under the trade name Alfaxan, and is licensed for use in both dogs and cats. Along with alfadolone, it is also one of the constituents of anesthetic drug mixture althesin.
Vet approved
Matched Description: … Along with alfadolone, it is also one of the constituents of anesthetic drug mixture althesin. …
Phosphorus P-32
Phosphorus P-32 is a radioactive isotope of phosphorus with beta particle-emitting radiocytotoxic activity. Emitted by phosphorus P32, beta particles directly damage cellular DNA and, by ionizing intracellular water to produce several types of cytotoxic free radicals and superoxides, indirectly damage intracellular biological macromolecules, resulting in tumor cell death.
Experimental
Matched Description: … Phosphorus P-32 is a radioactive isotope of phosphorus with beta particle-emitting radiocytotoxic activity ... particles directly damage cellular DNA and, by ionizing intracellular water to produce several types of …
Avasopasem manganese
Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide dismutase (SOD) being investigated for the reduction of radiation-induced severe oral mucositis.[L27246, L27256] This drug has potential application for radiation-induced esophagitis and oral mucositis, in addition to being currently tested against COVID-19.
Investigational
Matched Description: … Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide ... dismutase (SOD) being investigated for the reduction of radiation-induced severe oral mucositis. …
1-Testosterone
1-Testosterone is an anabolic steroid that differs from testosterone by having a 1,2-double bond instead of 4,5-double bond in its A ring.
Experimental
Illicit
Investigational
Matched Description: … Testosterone is an anabolic steroid that differs from testosterone by having a 1,2-double bond instead of …
Troxacitabine
Troxacitabine is a nucleoside analog with antineoplastic activity. There has been growing interest in its development for the treatment of patients with refractory lymphoproliferative conditions.
Investigational
Matched Description: … There has been growing interest in its development for the treatment of patients with refractory lymphoproliferative …
Anatibant
Anatibant is a selective, very potent, small-molecule Bradykinin B2 receptor antagonist. It is developed for the for the treatment of traumatic brain injury (TBI).
Investigational
Matched Description: … It is developed for the for the treatment of traumatic brain injury (TBI). …
AV608
AV608 is a NK-1 antagonist. It is developed for the treatment of Social anxiety disorder (SAD), irritable bowel syndrome (IBS) and overactive bladder (OAB).
Investigational
Matched Description: … It is developed for the treatment of Social anxiety disorder (SAD), irritable bowel syndrome (IBS) and …
PV903
PV903 is a self administered vaginally delivered recombinant protein for the treatment of recurrent miscarriage, resulting from an intolerant immune response to the developing foetus.
Investigational
Matched Description: … PV903 is a self administered vaginally delivered recombinant protein for the treatment of recurrent miscarriage …
OMS-103HP
OMS103HP is the first drug being developed to improve joint function following arthroscopic surgery, one of the most common procedures performed today by orthopedic surgeons.
Investigational
Matched Description: … OMS103HP is the first drug being developed to improve joint function following arthroscopic surgery, one of …
Strontium malonate
Strontium malonate is being developed as a novel orally available pharmaceutical for the treatment and prevention of osteoporosis. It is being developed by Osteologix Inc.
Investigational
Matched Description: … malonate is being developed as a novel orally available pharmaceutical for the treatment and prevention of …
Cetyl ethylhexanoate
Cetyl ethylhexanoate is an ester of cetyl alcohol and 2-ethylhexanoic acid. It is present in cosmetic products as a skin conditioning agent and emollient.
Experimental
Matched Description: … Cetyl ethylhexanoate is an ester of cetyl alcohol and 2-ethylhexanoic acid. …
Displaying drugs 6626 - 6650 of 8235 in total