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Displaying drugs 651 - 675 of 4840 in total
Farudodstat (ASLAN003) is under investigation in clinical trial NCT03451084 (A Dose Optimisation Study of ASLAN003 in Acute Myeloid Leukemia).
Investigational
Matched Synonyms: … 2-(3,5-difluoro-3'-methoxybiphenyl-4-ylamino)nicotinic acid ... 2-((3,5-difluoro-3'-methoxy-1,1'-biphenyl-4-yl)amino)nicotinic acid ... 2-((3,5-DIFLUORO-3'-METHOXY(1,1'-BIPHENYL)-4-YL)AMINO)-3-PYRIDINECARBOXYLIC ACID
Matched Iupac: … 2-({3,5-difluoro-3'-methoxy-[1,1'-biphenyl]-4-yl}amino)pyridine-3-carboxylic acid
Matched Categories: … Acids, Heterocyclic …
Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with pseudoephedrine. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons,...
Approved
Matched Description: … [A193698] Ephedrine acts as both a direct and indirect sympathomimetic. ... It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of ... norepinephrine from sympathetic neurons, inhibiting norepinephrine reuptake and displacing more norepinephrine …
Matched Salts cas: … 1405-94-3
Matched Salts name: … Ephedrine hydrochloride
Matched Categories: … Adrenergic and Dopaminergic Agents ... Alimentary Tract and Metabolism ... Alpha-and Beta-adrenergic Agonists ... Epinephrine and similars ... Herbs and Natural Products …
Matched Products: … Edeline Injection 30 mg/ml ... RINITALMIT LIQUIDE, 30 ML ... EPHEDRINE HYDROCHLORIDE
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Synonyms: … [4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo …
Matched Iupac: … [4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-[(carbamoyloxy)methyl]-7-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo …
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose ... ANIKEF STERILE 1.5G ... ANIKEF STERILE 750MG …
Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment...
Approved
Investigational
Matched Synonyms: … 11α,15α-dihydroxy-9-oxo-13-trans-prostenoic acid ... (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid
Matched Iupac: … 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid
Matched Description: … intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and ... This drug causes vasodilation by directly affecting vascular and ductus arteriosus (DA) smooth muscle …
Matched Mixtures name: … Caverject Sterile Powder - Kit 11.9mcg /vial …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated ... Genito Urinary System and Sex Hormones …
Matched Products: … Vitaros 3 mg/g - Creme ... VİRİREC 3 MG/G KREM, 4 ADET ... PROSTAVASIN 20 MCG I.A/I.V INFÜZYON IÇIN KURU TOZ IÇEREN AMPUL, 30 AMPUL …
Flavoring agent sweeter than sugar, metabolized as phenylalanine and aspartic acid.
Investigational
Nutraceutical
Matched Synonyms: … 3-Amino-N-(α-methoxycarbonylphenethyl) succinamic acid ... 3-Amino-N-(alpha-methoxycarbonylphenethyl) succinamic acid ... 3-Amino-N-(α-carboxyphenethyl)succinamic acid N-methyl ester …
Matched Iupac: … (3S)-3-amino-3-{[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]carbamoyl}propanoic acid
Matched Description: … Flavoring agent sweeter than sugar, metabolized as phenylalanine and aspartic acid. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Diet, Food, and Nutrition …
Matched Products: … SIVETA TABLET, 300 ADET ... ASTAT 10 MG TABLET, 300 ADET ... UNOTAT 10 MG TABLET, 300 ADET …
Experimental
Matched Synonyms: … 3-deoxy-α-D-manno-oct-2-ulopyranosonic acid ... α-2-keto-3-deoxyoctulosonic acid pyranose …
Matched Name: … 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid
Matched Iupac: … (2R,4R,5R,6R)-6-[(1R)-1,2-dihydroxyethyl]-2,4,5-trihydroxyoxane-2-carboxylic acid
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … 2-amino-3-(4-bromobenzoyl)benzeneacetic acid ... [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
Matched Salts cas: … 120638-55-3
Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Synonyms: … 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine …
Matched Iupac: … (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}propyl)dimethylamine …
Matched Description: … and clomipramine. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... than secondary amine TCAs, such as nortriptyline and desipramine. …
Matched Salts name: … Imipramine hydrochloride
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Heterocyclic Compounds, 3-Ring …
Matched Products: … SILEDX-3 ... Imipramine Hydrochloride ... Imipramine hydrochloride
Gamolenic acid, or gamma-linolenic acid (γ-Linolenic acid) or GLA, is an essential fatty acid (EFA) comprised of 18 carbon atoms with three double bonds that is most commonly found in human milk and other botanical sources . It is an omega-6 polyunsaturated fatty acid (PUFA) also referred to as 18:3n-6;...
Approved
Investigational
Matched Synonyms: … 18:3 (n-6) ... gamoleic acid ... Gamolenic acid
Matched Name: … Gamolenic acid
Matched Iupac: … (6Z,9Z,12Z)-octadeca-6,9,12-trienoic acid
Matched Description: … It is an omega-6 polyunsaturated fatty acid (PUFA) also referred to as 18:3n-6; 6,9,12-octadecatrienoic ... acid; and cis-6, cis-9, cis-12- octadecatrienoic acid [F27]. ... ] and [DB11238] are rich sources of gamolenic acid. …
Matched Categories: … Fatty Acids, Omega-6 ... Fatty Acids ... Fatty Acids, Essential ... Fatty Acids, Unsaturated ... gamolenic acid
Experimental
Matched Name: … 3-Amino-3-Oxopropanoic Acid
Matched Iupac: … 2-carbamoylacetic acid
Lonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK). In such way LND could impair energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and by some cytotoxic drugs.
Investigational
Matched Synonyms: … 1-(2,4-dichlorbenzyl)-indazole-3-carboxylic acid ... diclondazolic acid
Matched Iupac: … 1-[(2,4-dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid
Matched Description: … energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy...
Approved
Experimental
Investigational
Matched Description: … and magnesium carbonate. ... [A32810] Further, the mineral helps regulate blood pressure and is necessary for RNA, DNA and protein ... Magnesium is classified as an alkaline earth metal and has 2 hydration shells. …
Matched Mixtures name: … Calcium Folic Acid Plus D Chewable ... Omega-3 Rx Complete ... Folet One …
Matched Products: … Kordel’s Magnesium Amino Acid Chelate 750 Capsules ... BIOLECTRA MAGN 365 FOR ORA ... BIOLECTRA MAGN 365 FOR ZIT …
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Synonyms: … (2R)-2-acetylamino-3-sulfanylpropanoic acid ... (R)-2-acetylamino-3-mercaptopropanoic acid ... Mercapturic acid
Matched Iupac: … (2R)-2-acetamido-3-sulfanylpropanoic acid
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal ... ASIST C 600 MG-300 MG TOZ IÇEREN SAŞE,30 SAŞE …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur ... Cough and Cold Preparations …
Matched Products: … XPECTO 300 MG SAŞE, 30 ADET ... N-ACETILCISTEINA 300 MG/3 ML ... SISTECS 300 MG/3 ML ÇÖZELTI, 10 ADET …
Experimental
Matched Products: … LACRYVISC STERILE OPTH 10 GR GOZ JELI ... VISCOTEARS STERİL OFTALMİK JEL, 10 G …
Talc is a mineral composed primarily of magnesium, silicon and oxygen. It is a substance often found in cosmetic and personal hygiene products including baby powder, adult body powders and facial powders. Talc helps absorb moisture, freshen materials, and reduce friction to prevent rashes. Although talc has been widely used...
Approved
Matched Synonyms: … Sterile talc powder ... Talc Powder, Sterile
Matched Description: … by approximately 30 percent. ... body powders and facial powders. ... Talc is a mineral composed primarily of magnesium, silicon and oxygen. …
Matched Mixtures name: … Foot and Body Powder …
Matched Products: … Sterile Talc ... Steritalc 3g
Experimental
Matched Synonyms: … Adenylyl-(3'-5')-3'-uridylic acid ... Adenylyl-3'-5'-phospho-uridine-3'-monophosphate …
Matched Name: … Adenylyl-(3'-5')-uridine 3'-monophosphate …
Matched Iupac: … yl]oxy}phosphonic acid ... {[(2R,3S,4R,5R)-2-{[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl ... ]oxy}(hydroxy)phosphoryl)oxy]methyl}-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-hydroxyoxolan-3- …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Name: … 3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID
Matched Iupac: … 3-(carboxymethoxy)thieno[2,3-b]pyridine-2-carboxylic acid
Experimental
Matched Synonyms: … 3-Deoxy-arabino-hexonic acid ... D-2-keto-3-deoxygluconate …
Matched Name: … 3-deoxy-D-arabino-hexonic acid
Matched Iupac: … (2S,4S,5R)-2,4,5,6-tetrahydroxyhexanoic acid
Matched Categories: … Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids
Experimental
Matched Synonyms: … (S)-2-amino-3-(3-hydroxy-isoxazol-4-yl)propionic acid
Matched Iupac: … (2S)-2-amino-3-(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)propanoic acid
Ataluren is a novel, orally administered drug that targets nonsense mutations. Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk. More specifically, ataluren is used in the small group of patients whose...
Approved
Investigational
Matched Synonyms: … 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid
Matched Iupac: … 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid
Matched Description: … use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and ... This drug does not yet have approval by the US Food and Drug Administration or by Health Canada for any …
Procysteine has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Synonyms: … (-)-2-OXO-4-THIAZOLIDINECARBOXYLIC ACID ... (R)-2-OXOTHIAZOLIDINE-4-CARBOXYLIC ACID ... L-2-OXO-4-THIAZOLIDINECARBOXYLIC ACI
Matched Name: … Oxothiazolidinecarboxylic acid
Matched Iupac: … (4R)-2-oxo-1,3-thiazolidine-4-carboxylic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …
Alclofenac is a non-steroidal anti-inflammatory drug. It was withdrawn from the market in the United Kingdom in 1979.
Approved
Withdrawn
Matched Synonyms: … [4-(allyloxy)-3-chlorophenyl]acetic acid ... 3-Chloro-4-(2-propenyloxy)benzeneacetic acid ... (4-Allyloxy-3-chlorphenyl)essigsäure …
Matched Iupac: … 2-[3-chloro-4-(prop-2-en-1-yloxy)phenyl]acetic acid
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Acids, Carbocyclic ... Carboxylic Acids ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Investigational
Matched Synonyms: … acid ... acid ... acid
Matched Iupac: … acid ... 2-{3-[(3R)-3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)butoxy]phenyl}acetic …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
Zorubicin is a drug of the anthracycline class - a class of medications that have historically demonstrated effective chemotherapy for a variety of cancer types.
Experimental
Matched Synonyms: … Benzoic acid hydrazide, 3-hydrazone with daunorubicin …
Matched Salts name: … Zorubicin hydrochloride
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … 4-Amino-3-(4-chlorophenyl)butyric acid ... DL-4-Amino-3-p-chlorophenylbutanoic acid ... beta-(Aminomethyl)-p-chlorohydrocinnamic acid
Matched Iupac: … 4-amino-3-(4-chlorophenyl)butanoic acid
Matched Description: … Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. ... [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... used to manage severe muscle spasms of cerebral or spinal cord origins, including multiple sclerosis and
Matched Salts cas: … 28311-31-1 …
Matched Salts name: … Baclofen hydrochloride
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... gamma-Aminobutyric Acid-ergic Agonist …
Displaying drugs 651 - 675 of 4840 in total