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Displaying drugs 676 - 700 of 883 in total
Roflumilast is a highly selective phosphodiesterase-4 (PDE4) inhibitor. PDE4 is a major cyclic-3',5′-adenosinemonophosphate (cyclic AMP, cAMP)-metabolizing enzyme expressed on nearly all immune and pro-inflammatory cells, in addition to structural cells like those of the smooth muscle or epithelium. The resultant increase in intracellular cAMP induced by roflumilast's inhibition of PDE4...
Approved
Matched Description: … [L46546] It was first approved by the EMA in July 2010, and by the FDA in January 2018. ... adenosinemonophosphate (cyclic AMP, cAMP)-metabolizing enzyme [L37564] expressed on nearly all immune and ... The cream formulation was first approved by the FDA in July 2022 [L42580] and by Health Canada in April …
Matched Products: … DAXAS 500 MCG FILM-COATED TABLETS ... DAXAS 500 MCG FILM TABLET, 30 ADET ... DAXAS 500 MCG FILM TABLET, 90 ADET …
The chemical compound calcium acetate is the calcium salt of acetic acid. It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Approved
Investigational
Matched Mixtures name: … OSVAREN 435 MG/235 MG 180 FILM KAPLI TABLET …
Matched Categories: … Alimentary Tract and Metabolism ... ascorbic acid (vit C) and calcium ... calcium acetate and magnesium carbonate ... Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … FOSFAT-EX 700 MG FILM TABLET,FILM TABLET, 100 ADET ... FIX-AT 475MG FILM KAPLI TABLET, 90 ADET ... FIX-AT 950 MG FILM KAPLI TABLET, 90 ADET …
Siponimod, also known as Mayzent, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS). It was approved by the FDA on March 26, 2019 and by Health Canada on February 20, 2020. This drug is considered a sphingosine-1-phosphate (S1P) receptor modulator and is thought to...
Approved
Investigational
Matched Description: … , disrupting communication between the brain and other parts of the body. ... It was approved by the FDA on March 26, 2019 [L5792] and by Health Canada on February 20, 2020. ... [L12171] This drug is considered a _sphingosine-1-phosphate (S1P) receptor modulator_ and is thought …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … MAYZENT FILM-COATED TABLET 2MG ... MAYZENT FILM-COATED TABLET 0.25MG …
Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Description: … acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and
Matched Mixtures name: … FEMARİS PLUS 150 MG/5600 IU FİLM KAPLI TABLET, 3 ADET …
Matched Categories: … Calcium-Regulating Hormones and Agents ... risedronic acid and colecalciferol ... risedronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization ... risedronic acid, calcium and colecalciferol, sequential …
Matched Products: … ACTEDAY 5 MG FİLM TABLET, 28 ADET ... BONEPLUS 5 MG FİLM TABLET, 28 ADET ... INDRONATE FILM-COATED TABLET 35 MG …
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date,...
Approved
Investigational
Matched Description: … widely prescribed in the Netherlands, New Zealand, and the US. ... Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives ... [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is …
Matched Mixtures name: … IMPLICOR 50MG/5MG FILM-COATED TABLETS ... IMPLICOR 25MG/5MG FILM-COATED TABLETS ... IMPLICOR FILM-COATED TABLET 25 mg/5 mg …
Matched Categories: … Beta Blocking Agents and Thiazides ... metoprolol and felodipine ... metoprolol and ivabradine ... metoprolol and thiazides ... metoprolol and amlodipine …
Matched Products: … Metoprolol Tartrate film coated ... PROBLOK 100 MG FİLM TABLET, 20 ADET ... LOPRESOR 100 MG FILM TABLET, 20 ADET …
Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.[L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). Doravirine is formally indicated for the treatment of...
Approved
Investigational
Matched Description: … Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and ... adult patients with no prior antiretroviral treatment experience, further expanding the possibility and
Matched Mixtures name: … DELSTRIGO FILM COATED TABLET 100MG/300MG/300MG …
Matched Categories: … lamivudine, tenofovir disoproxil and doravirine …
Matched Products: … PIFELTRO FILM-COATED TABLET 100MG ... PİFELTRO 100 MG FİLM KAPLI TABLET, 30 ADET …
Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
Approved
Investigational
Matched Description: … Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and ... enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Fluorouracil and prodrugs ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … KAPETRAL FILM-COATED TABLET 500MG ... KAPETRAL FILM-COATED TABLET 150MG ... XELODA (500 MG FILM-COATED TABLETS) …
Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. It is branded as Inhibace in Canada and...
Approved
Matched Description: … It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries ... Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. …
Matched Mixtures name: … ACEPRIX PLUS 5 MG/12.5 MG FILM TABLET, 30 ADET ... İNHİBACE PLUS 5 MG/12,5 MG FILM KAPLI TABLET, 28 ADET …
Matched Categories: … ACE Inhibitors and Diuretics ... cilazapril and diuretics …
Matched Products: … ACEPRIX 1 MG FILM TABLET, 30 ADET ... ACEPRIX 5 MG FILM TABLET, 30 ADET ... ACEPRIX 2.5 MG FILM TABLET, 30 ADET …
Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Description: … Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (> …
Matched Mixtures name: … Alogliptin and Pioglitazone ... Alogliptin and Pioglitazone ... Alogliptin and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and alogliptin ... pioglitazone and alogliptin ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Nesina 25mg Film-Coated Tablet ... Nesina 6.25mg Film-Coated Tablet ... Nesina 12.5mg Film-Coated Tablet …
Tucatinib is a kinase inhibitor drug used with trastuzumab and capecitabine in the treatment of unresectable or metastatic HER-2 positive breast cancer. It was developed by Seattle Genetics and approved by the FDA on April 17, 2020. Tucatinib is a promising new treatment for patients with metastatic breast cancer who...
Approved
Investigational
Matched Description: … It was developed by Seattle Genetics and approved by the FDA on April 17, 2020. ... Tucatinib is a kinase inhibitor drug used with [trastuzumab] and [capecitabine] in the treatment of unresectable …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … TUKYSA (TUCATINIB) FILM-COATED TABLETS 150 mg ... TUKYSA (TUCATINIB) FILM-COATED TABLETS 50 mg …
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Description: … has since become available as a generic and as a brand name product. ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and ... L6325,L6328,L6331] the drug still sees extensive use worldwide via millions of prescriptions annually and
Matched Mixtures name: … LORCLAST 5 MG/10 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 30 ADET ... DESMONT 5/10 MG 90 FILM KAPLI TABLET ... LEPIXOS 5 MG/10 MG FILM TABLET ,30 ADET …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SINAIR 10 MG FILM KAPLI TABLET ,FILM TABLET, 28 ADET ... Oxair Film Coated Tablet 10mg ... OXAIR FILM COATED TABLET 10MG …
Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically relapsing forms. The FDA label states an important warning about the risk of hepatoxicity and...
Approved
Matched Description: … Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting ... It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically ... The FDA label states an important warning about the risk of hepatoxicity and teratogenicity for patients …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Leflunomide and metabolite …
Matched Products: … AUBAGIO FILM-COATED TABLETS 14mg ... AUBAGIO 14mg Film-coated Tablets ... AVORAN 14 MG FİLM KAPLI TABLET, 28 ADET …
Exemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive (also called hormone-receptor-positive, estrogen-responsive) breast cancer in postmenopausal women. It irreversibly binds to the active site of the enzyme resulting in permanent inhibition.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … FEMMEX 25 MG FILM TABLET, FILM TABLET, 30 ADET ... EXACCORD 25 FILM COATED TABLET 25 MG ... EXEMESTANE STADA FILM COATED TABLET 25mg …
Cobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction pathway. It has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of patients with unresectable or...
Approved
Investigational
Matched Description: … Cobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated ... protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction ... It has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … COTELLIC 20 MG FILM KAPLI TABLET,63 FILM KAPLI TABLET ... COTELLIC FILM COATED TABLET 20MG ... COTELLIC FILM-COATED TABLET 20 MG …
Ginkgo biloba extract contains a group of terpene lactones (notably, ginkgolides and diterpenes) and ginkgo flavone glycosides (notably, ginkgetin, bilobetin, and sciadopitysin) that have antioxidant and vasoactive properties. Most of the studies that investigate the effect of ginkgo biloba use the standardized extract of Ginkgo biloba (EGb) 761 (EGb761), which...
Approved
Investigational
Nutraceutical
Matched Description: … _Ginkgo biloba_ extract contains a group of terpene lactones (notably, ginkgolides and diterpenes) and ... ginkgo flavone glycosides (notably, ginkgetin, bilobetin, and sciadopitysin) that have antioxidant and ... _Ginkgo biloba_ is found in a number of homeopathic and over-the-counter herbal products and dietary …
Matched Mixtures name: … Bee Venom Wart And Tags Removal Treatment …
Matched Categories: … donepezil, memantine and Ginkgo folium …
Matched Products: … BILOKAN SUPRA FILM TABLET, 60 ADET ... BILOKAN SUPRA FILM TABLET, 90 ADET ... SEREMAKS FORT FİLM TABLET, 20 ADET …
Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR) gene transcribe the chimeric protein...
Approved
Investigational
Matched Description: … pathogenesis of CML and 15-30% of ALL cases. ... ALL, dasatinib inhibits the active and inactive conformations of the ABL kinase domain. ... A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … DASİKAM 20 MG FİLM KAPLI TABLET ... DASİKAM 50 MG FİLM KAPLI TABLET ... DASİKAM 70 MG FİLM KAPLI TABLET …
Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles). Famciclovir is a prodrug of penciclovir with higher oral bioavailability.
Approved
Investigational
Matched Categories: … Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … FAMVIR 250 MG FILM TABLET, 21 ADET ... VIRMOL 125 MG FILM KAPLI TABLET, 14 ADET ... VIRMOL 500 MG FILM KAPLI TABLET, 14 ADET …
Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.
Approved
Investigational
Matched Description: … Ramelteon has not been shown to produce dependence and has shown no potential for abuse. …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … RAMELDA 8 MG FILM KAPLI TABLET,30 ADET ... RAMELDA 8 MG FILM KAPLI TABLET,10 ADET ... ROZEREST 8 MG FİLM KAPLI TABLET, 10 ADET …
Desogestrel, a prodrug, is a third generation progestogen and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada. It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent in nortestosterone can enhance the biological...
Approved
Matched Description: … family which was largely used in Europe before being approved in the US and Canada. ... Desogestrel, a prodrug, is a third generation progestogen[A176315] and hence, a member of the gonane ... [A176339] It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent …
Matched Mixtures name: … Desogestrel and Ethinyl Estradiol and Ethinyl Estradiol ... Desogestrel and Ethinyl Estradiol and Ethinyl Estradiol ... Desogestrel and Ethinyl Estradiol …
Matched Categories: … desogestrel and estrogen ... Combination Contraceptives (with Estrogen and derivatives) ... desogestrel and ethinylestradiol ... Genito Urinary System and Sex Hormones ... desogestrel and ethinylestradiol …
Matched Products: … Desirett 75mcg film-coated tablet ... Azalia 0.075 mg film-coated tablet ... DESIRETT 75 MCG FILM KAPLI TABLET ,28 ADET …
Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. Dexibuprofen has a...
Approved
Investigational
Matched Description: … the racemic ibuprofen and displays improved oral bioavilability [A19259]. ... Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with ... It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen …
Matched Categories: … Ibuprofen and isomer ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … IBUDEX 400 FILM TABLET, 10 ADET ... IBUDEX 400 FILM TABLET, 30 ADET ... IBUDEX 400 MG FILM TABLET, 20 ADET …
Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Description: … [A178192] It promotes sodium and water excretion and potassium retention. ... It binds to mineralocorticoid receptors and functions as aldosterone antagonists. ... [L44602] Off-label uses of spironolactone include hirsutism, female pattern hair loss, and adult acne …
Matched Mixtures name: … Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SPYLACTON 50 MG FILM KAPLI TABLET, 20 ADET ... SPYLACTON 100 MG FILM KAPLI TABLET, 20 ADET ... SPYLACTON 25 MG FILM TABLET, 20 ADET …
Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.
Approved
Matched Description: … Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems. …
Matched Mixtures name: … UNIRETIC 15 MG/ 25 MG FILM KAPLI TABLET, 30 ADET ... UNIRETIC 7,5 MG/ 12.5 MG FILM KAPLI TABLET, 30 ADET ... Moexipril Hydrochloride and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Diuretics ... moexipril and diuretics …
Matched Products: … UNIVASC 15 MG FILM TABLET, 20 ADET ... UNIVASC 7,5 MG FILM TABLET, 20 ADET …
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.[A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.[A256267,A256463] UDCA was first characterized...
Approved
Investigational
Matched Description: … [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by ... [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary …
Matched Categories: … Bile Acids and Salts ... Alimentary Tract and Metabolism ... Bile acids and derivatives ... Bile and Liver Therapy ... Cholagogues and Choleretics …
Matched Products: … URSOKOL 250 MG FILM TABLET,100 ADET ... URSOKOL 500 MG FILM TABLET,100 ADET ... URSOKOL 750 MG FİLM TABLET, 50 ADET …
Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full...
Approved
Investigational
Matched Description: … In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. ... Food and Drug Administration warned that Varenicline, in the form of Pfizer Inc's quit-smoking drug, ... Chantix, has been associated with seizures and that some patients who drink while taking the drug may …
Matched Mixtures name: … CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET ... CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET ... CHAMPIX 0,5 MG 1 MG FILM KAPLI TABLET, 11 VE 14 ADET …
Matched Products: … CHAMPIX 0.5MG FILM-COATED TABLETS ... CHAMPIX 1.0MG FILM-COATED TABLETS ... CHAMPIX 1 MG FILM KAPLI TABLET, 28 ADET …
Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired....
Approved
Matched Products: … FERRIPROX FILM-COATED TABLET 500 mg ... Ferriprox 1000mg Film-Coated Tablet ... HİERO 500 MG FİLM KAPLI TABLET, 100 ADET …
Displaying drugs 676 - 700 of 883 in total