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Displaying drugs 51 - 75 of 3697 in total

Novobiocin

Novobiocin is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189) Novobiocin sodium, a salt form of novobiocin, was initially approved in September 1964...
Approved
Investigational
Vet approved
Withdrawn
Matched Synonyms: … N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-β-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-chromen …
Matched Iupac: … -5-hydroxy-6-({4-hydroxy-3-[4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamido]-8-methyl-2-oxo-2H-chromen-7- …

Carprofen

Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Carprofen was previously used in human medicine for over 10 years (1985-1995). It was generally well tolerated, with the majority of adverse effects being mild,...
Approved
Vet approved
Withdrawn
Matched Synonyms: … (+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid …

Cyclacillin

A cyclohexylamido analog of penicillanic acid.
Approved
Matched Synonyms: … (2S,5R,6R)-6-{[(1-aminocyclohexyl)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane …
Matched Iupac: … (2S,5R,6R)-6-(1-aminocyclohexaneamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …

Fluconazole

Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole...
Approved
Investigational
Matched Products: … CANDIMAX 100 MG KAPSUL, 7 ADET ... FLUCORAL 100 MG KAPSÜL, 7 ADET ... FUNGAN 100 MG KAPSÜL, 7 ADET …

Meticillin

One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
Approved
Investigational
Matched Synonyms: … (2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Iupac: … (2S,5R,6R)-6-(2,6-dimethoxybenzamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …

Flucloxacillin

Antibiotic analog of cloxacillin.
Approved
Investigational
Matched Synonyms: … (2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …

Nafcillin

A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA. It may be used as a first-line therapy in...
Approved
Investigational
Matched Synonyms: … (2S,5R,6R)-6-[(2-ethoxy-1-naphthoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Iupac: … (2S,5R,6R)-6-(2-ethoxynaphthalene-1-amido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …

Budesonide

Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994. It is also available in a combination product...
Approved
Matched Mixtures name: … AIRBIR 3/100 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL, 60 KPS ... FORACORT 100 ... Symbicort 100 Turbuhaler …
Matched Products: … INFLACORT 100 MCG INHALER KAPSUL, 60 ADET ... ENTOCORT 0.02 MG/ML REKTAL SÜSPANSİYON HAZIRLAMAK İÇİN DAĞILABİLİR TABLET, 7 ADET ... BUDOLER 100 MCG İNHALASYON TOZU, KAPSÜL, 60 KAPSÜL …

Enmetazobactam

Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious infections. The combination product of enmetazobactam and cefepime was first approved by the FDA on February...
Approved
Matched Synonyms: … 1h-1,2,3-triazolium, 3-(((2s,3s,5r)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo(3.2.0)hept …

Topiramate

Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Salts cas: … 488127-49-7 …
Matched Products: … LETOP 100 MG TABLET, 60 ADET ... NOROMAT 100 MG FILM TABLET, 60 ADET ... XAMATE 100 MG FILM KAPLI TABLET, 60 ADET …

Nintedanib

Nintedanib is a small molecule kinase inhibitor used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC).[L8453,L8459] It was first approved for use in the United States in 2014. Within the spectrum of idiopathic pulmonary fibrosis treatment options, nintedanib is currently one...
Approved
Matched Products: … OFEV 100 MG YUMUSAK KAPSUL, 60 ADET ... VARGATEF 100 MG YUMUŞAK KAPSÜL , 60 ADET ... OFEV 150 MG YUMUSAK KAPSUL, 60 ADET …

Azacitidine

Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Products: … Onureg 200 mg Film Kaplı Tablet, 7 ADET ... Onureg 300 mg Film Kaplı Tablet, 7 ADET ... XPREZA 100 INJECTION 100 MG/VIAL …

Formoterol

Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers....
Approved
Investigational
Matched Mixtures name: … DULAMON 100 MCG/5 MCG BASINÇLI İNHALASYON, SÜSPANSİYON, 60 DOZ ... FİXHALER 12 MCG/100 MCG İNHALASYON TOZU, SERT KAPSÜL, 60 KAPSÜL ... FORACORT 100 …
Matched Products: … ATIMOS 12UG 100 HUEBE ... ATIMOS 12 MCG BASINCLI INHALASYON ÇÖZELTISI, 100 DOZ ... FORADIL 12 MCG INHALER KAPSUL, 60 ADET …

Papaverine

An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear,...
Approved
Investigational
Matched Products: … PAPAVERIN HCL BIOFARMA 60 MG / 2ML AMPUL, 100 ADET ... PAPAVERINE HCL 60 MG TABLET, 20 ADET ... PAPAVERIN HCL BIOFARMA 60 MG / 2ML AMPUL, 10 ADET …

Atomoxetine

Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention deficit hyperactivity disorder (ADHD). Also known as the marketed product Strattera, atomoxetine is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve developmentally inappropriate symptoms associated with ADHD including distractibility, short attention...
Approved
Matched Salts cas: … 82248-59-7 …
Matched Products: … STRATTERA 60 MG ... audalis 100 mg Filmtabletten ... ATOMOXETIN-NEURAX 100 MG …

Ertapenem

Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … 5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7- …
Matched Iupac: … -{[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7- …

Salmeterol

Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.[L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, salbutamol. Salmeterol was first described in the literature in 1988. Salmeterol's structure...
Approved
Matched Mixtures name: … PEFSAL 50 MCG/100 MCG İNHALER KAPSÜL, 60 ADET ... PAVTIDE DISKUS 100 MCG INHALASYON ICIN TOZ, 60 DOZ ... SERETIDE 100 MCG DISKUS INHALASYON İÇİN TOZ, 60 DOZ …
Matched Products: … SEREVENT DISKUS 60 ... SEREVENT DISKUS 60 EINZELD ... SEREVENT INHALER 25 MCG, 60 DOZ …

Quinidine

Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Synonyms: … (R)-(6-Methoxyquinolin-4-yl)((3S,4R,7S)-3-vinylquinuclidin-7-yl)methanol …

Guanfacine

Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension but is now indicated as an extended release tablet for the treatment of ADHD. Guanfacine was first described in the literature in 1974. Guanfacine was granted FDA approval on 27 October 1986.
Approved
Investigational
Matched Description: … Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially …
Matched Products: … GUAGO 1 MG UZATILMIŞ SALIMLI TABLET, 7 ADET ... GUAGO 2 MG UZATILMIŞ SALIMLI TABLET, 7 ADET ... GUAGO 3 MG UZATILMIŞ SALIMLI TABLET, 7 ADET …

Ursodeoxycholic acid

Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.[A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.[A256267,A256463] UDCA was first characterized...
Approved
Investigational
Matched Products: … UGEFAL 250 MG FILM KAPLI TABLET, 60 ADET ... URSOVEF 500 MG FILM KAPLI TABLET, 60 ADET ... UGEFAL 250 MG FILM KAPLI TABLET, TABLET, 60 ADET …

Dasatinib

Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR) gene transcribe the chimeric protein...
Approved
Investigational
Matched Products: … Dasikam 80 mg Film Kaplı Tablet, 60 ADET ... DAFANİB 70 MG FİLM KAPLI TABLET , 60 ADET ... DAFANİB 50 MG FİLM KAPLI TABLET , 60 ADET …

Dapsone

A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of...
Approved
Investigational
Matched Products: … VULGAREX %7,5 JEL, 60 G ... ด๊อปแซน-100 ... ด๊อปแซน - 100 …

Niacin

Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.[L7550,L7553,L7556,L7559,L7562,L7565]
Approved
Investigational
Nutraceutical
Matched Mixtures name: … Protect Plus SO 60 …
Matched Products: … Formula # 7 Tab 50mg ... Niacin 100 mg ... Niacin-100 Tab 100mg …

Axitinib

Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. It is reported to exhibit potency that is 50-450 times higher than that of the first generation...
Approved
Investigational
Matched Products: … Axitinib STADA 7 mg Filmtabletten ... Axitinib Sandoz 7 mg – Filmtabletten ... INLYTA 7 MG FİLM KAPLI TABLET, 28 ADET …

Memantine

Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Mixtures name: … MEGINGO 10/50 MG EFERVESAN TABLET, 100 ADET ... MEGINGO 10/80 MG EFERVESAN TABLET, 100 ADET ... MEGINGO 20/50 MG EFERVESAN TABLET, 100 ADET …
Matched Products: … ALZIA 10 MG FILM TABLET, 100 ADET ... FIXREM 5 MG FILM TABLET, 100 ADET ... FIXREM 10 MG FILM TABLET, 100 ADET …
Displaying drugs 51 - 75 of 3697 in total