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Displaying drugs 51 - 75 of 10766 in total
Calfactant is a sterile, non-pyrogenic lung surfactant intended for intratracheal instillation. It is an off-white suspension of an extract of natural surfactant from calf lungs suspended in 0.9% saline. Each milliliter of calfactant contains 35mg of phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and 0.65mg...
Approved
Matched Synonyms: … SF-RI 1
Matched Products: … ALVEOFACT 50 MG/1.2 ML INTRATRAKEAL STERİL APİROJEN SÜSPANSİYON, 1 ADET …
Adrenergic beta-agonist used to control premature labor.
Approved
Investigational
Matched Synonyms: … p-Hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)benzyl alcohol …
Matched Iupac: … 4-[(1S,2R)-1-hydroxy-2-{[2-(4-hydroxyphenyl)ethyl]amino}propyl]phenol …
Matched Products: … PRE-PAR 50 MG/5 ML IM/IV ÇÖZELTİ İÇEREN AMPUL, 1 AMPUL …
Enalapril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor drug class that works on the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and fluid and electrolyte homeostasis. Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the renin-angiotensin-aldosterone system to lower blood...
Approved
Vet approved
Matched Synonyms: … 1-(N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester ... (S)-1-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline ... (S)-1-{(S)-2-[1-((S)-Ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]pyrrolidine-2-carboxylic acid …
Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher disease.[A3752,L41404] Gaucher disease is a rare genetic disorder characterized by the deficiency of acid β-glucosidase, an enzyme that converts glucosylceramide into glucose and ceramide. In patients with Gaucher disease, the accumulation of glucosylceramide leads to...
Approved
Investigational
Matched Synonyms: … N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)-2-propanyl]octanamide …
Matched Iupac: … N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl]octanamide …
Matched Description: … Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher ... the FDA in August 2014 as an oral substrate reduction therapy for the first-line treatment of type 1 ... [L41404,A7634] Enzyme replacement continues to be the standard of care for the treatment of type 1 Gaucher …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Stiripentol is an antiepileptic agent that is an aromatic allylic alcohol drug, which makes it structurally unique from other antiepileptic drugs.[A19740, A250825] The clinical development and marketing of stiripentol were first delayed due to the drug's potent inhibitory effects on hepatic cytochrome P450 (CYP) enzymes. However, its clinical efficacy as...
Approved
Matched Synonyms: … 1-(1,3-Benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol ... 4,4-Dimethyl-1-((3,4-methylenedioxy)phenyl)-1-penten-3-ol …
Matched Iupac: … (1E)-1-(2H-1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … NRL-1 ... 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Salts cas: … 52468-36-7 …
Matched Products: … DIAPAM 2 MG DRAJE, 50 ADET ... DIAPAM 5 MG DRAJE, 50 ADET ... DİAZEM 2 MG KAPSÜL, 50 KAPSÜL …
Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Synonyms: … delta(1)-Hydrocortisone ... delta(1)-Dehydrocortisol ... delta(1)-Dehydrohydrocortisone …
Matched Iupac: … (1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H, …
Matched Products: … PREDNI H INJEKT 50 ... SOLU DECORTIN H 50 ... PROZOLON KREM, 50 G …
Cefoperazone is a semisynthetic broad-spectrum cephalosporin proposed to be effective against Pseudomonas infections. It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia. While its...
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-((R)-2-(4-Ethyl-2,3-dioxo-1-piperazinylcarboxamido)-2-(4-hydroxyphenyl)acetamido)-3-((1-methyl ... (6R,7R)-7-[[2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1- ... -1H-tetrazol-5-yl)thiomethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure …
Matched Iupac: … 1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic ... (6R,7R)-7-[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetamido]-3-{[( …
Matched Mixtures name: … SEFBAKTAM 1 GR ENJEKTABL FLAKON, 1 FLAKON + 1 AMPUL ... SULZON 1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET, 1 AMPUL ... SULZON 2G/1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET, 1 AMPUL …
Matched Products: … CEFOBID 1 GR FLAKON, 1 ADET ... EKOBID 1 G IM/IV ENJEKSIYONLUK TOZ IÇEREN FLAKON , FLAKON, 1 ADET, 1 AMPUL ... STABIXIN-1
Adagrasib (MRTX849) is an oral, small-molecule KRAS inhibitor developed by Mirati Therapeutics. KRAS mutations are highly common in cancer and account for approximately 85% of all RAS family mutations. However, the development of KRAS inhibitors has been challenging due to their high affinity for guanosine triphosphate (GTP) and guanosine diphosphate...
Approved
Investigational
Matched Synonyms: … )methoxy)pyrido(3,4-d)pyrimidin-4-yl)-1-(2-fluoro-1-oxo-2-propen-1-yl)-, (2s)- ... ((2s)-4-(7-(8-chloronaphthalen-1-yl)-2-(((2s)-1- methylpyrrolidin-2-yl)methoxy)-5,6,7,8- tetrahydropyrido ... 2-piperazineacetonitrile, 4-(7-(8-chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-(((2s)-1-methyl-2-pyrrolidinyl …
Matched Iupac: … 2-[(2S)-4-[7-(8-chloronaphthalen-1-yl)-2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-5H,6H,7H,8H-pyrido[3,4 ... -d]pyrimidin-4-yl]-1-(2-fluoroprop-2-enoyl)piperazin-2-yl]acetonitrile …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.
Approved
Matched Synonyms: … 1-propanol ... 1-proponol …
Matched Iupac: … propan-1-ol …
Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia. It is marketed under the brand name Pletal by Otsuka Pharmaceutical Co.. Cilostazol works by inhibiting both primary and secondary aggregation and reducing...
Approved
Investigational
Matched Synonyms: … 6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydrocarbostyril ... 3,4-dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone ... 6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone …
Matched Iupac: … 6-[4-(1-cyclohexyl-1H-1,2,3,4-tetrazol-5-yl)butoxy]-1,2,3,4-tetrahydroquinolin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ANTIPLAT 50 ... NALETAL - 50 ... ไซลอซซา-50
Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and presentation, including neutropenia and thrombocytopenia. Further mutations leading to increased proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a poor prognosis.[A215082, A215092] Among treatment options, nucleoside analogues such as...
Approved
Investigational
Matched Synonyms: … 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-s-triazin-2(1H)-one …
Matched Iupac: … 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … DESİTAB 50 MG IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET ... DESİTU 50 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET ... DESİBEM 50 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET …
Cannabidiol, or CBD, is one of at least 85 active cannabinoids identified within the Cannabis plant. It is a major phytocannabinoid, accounting for up to 40% of the Cannabis plant's extract, that binds to a wide variety of physiological targets of the endocannabinoid system within the body. Although the exact...
Approved
Investigational
Matched Synonyms: … (1'R,2'R)-5'-methyl-4-pentyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydrobiphenyl-2,6-diol ... .DELTA.1(2)-TRANS-CANNABIDIOL …
Matched Iupac: … 2-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol …
Matched Description: … CBD is currently available in Canada within a 1:1 formulation with tetrahydrocannbinol (THC) (as the ... largely mediated through two members of the G-protein coupled receptor family, cannabinoid receptors 1 ... that CBD also activates 5-HT1A/2A/3A serotonergic and TRPV1–2 vanilloid receptors, antagonizes alpha-1
Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption. Isopropyl myristate has been largely studied and impulsed as a skin penetration enhancer. At the moment the primary usage for which isopropyl myristate is formally indicated is as the active...
Approved
Experimental
Matched Synonyms: … 1-Methylethyl tetradecanoate …
Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Synonyms: … 1-dehydro-6α-methylhydrocortisone ... delta(1)-6alpha-Methylhydrocortisone …
Matched Iupac: … (1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH …
Matched Salts cas: … 53-36-1
Matched Products: … PREDNOL-L 20 MG LİYOFİLİZE ENJEKTABL AMPUL, 50 ADET ... PREDNOL-L 40 MG LİYOFİLİZE ENJEKTABL AMPUL, 50 ADET ... PREDNOL-L 250 MG LİYOFİLİZE ENJEKTABL AMPUL, 50 ADET …
Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Matched Synonyms: … (3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine …
Matched Iupac: … methyl[(3S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl]amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … DULOXETIN 1 A PHA 30MG HKP ... DULOXETIN 1 A PHA 60MG HKP …
Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZeneca under the trade name Chirocaine. In particular, the specific levobupivacaine enantiomer is a worthwhile pursuit because it demonstrates less vasodilation and possesses a...
Approved
Investigational
Matched Synonyms: … (S)-1-butyl-2',6'-pipecoloxylidide ... L-(-)-1-Butyl-2',6'-pipecoloxylidide …
Matched Iupac: … (2S)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide …
Matched Products: … CHIROCAINE 50 MG/10 ML INF. ICIN KONS. COZELTI ICEREN 10ML X 10 AMPUL …
Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang. It is also a significant dermatologic sensitizer and allergen, and as a result has been restricted to 200 p.p.m. since 1998 according to guidelines issued by...
Approved
Experimental
Matched Synonyms: … 2-methoxy-4-(prop-1-en-1-yl)phenol ... 1-Hydroxy-2-methoxy-4-propen-1-ylbenzene …
Matched Iupac: … 2-methoxy-4-(prop-1-en-1-yl)phenol …
Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure.
Approved
Matched Synonyms: … N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine ... (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine …
Matched Iupac: … [(1R)-1-(naphthalen-1-yl)ethyl]({3-[3-(trifluoromethyl)phenyl]propyl})amine …
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Synonyms: … -1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate ... (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium …
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium ... 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia …
Matched Products: … CEFEPIMA 1 G ... ROXIPIME 1 GR IM/IV ENJEKTABL TOZ ICEREN FLAKON, 1 ADET ... CEFEPEN INJECTION 1 g …
Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
Approved
Matched Synonyms: … 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine ... 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine ... 9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine …
Matched Products: … EX-LOVIR % 1 KREM 2 G ... PENSIVIR %1 KREM , 2 G ... PENSIVIR %1 KREM , 5 G …
Diphenylpyraline is an antihistamine. Antihistamines used in the treatment of allergy act by competing with histamine for H 1-receptor sites on effector cells. Antihistamines prevent, but do not reverse, responses mediated by histamine alone. Antihistamines antagonize, in varying degrees, most of the pharmacological effects of histamine, including urticaria and pruritus.
Approved
Investigational
Matched Synonyms: … 1-methyl-4-piperidyl benzhydryl ether ... 4-(benzhydryloxy)-1-methylpiperidine ... 1-methyl-4-hydroxypiperidine benzhydryl ether …
Matched Iupac: … 4-(diphenylmethoxy)-1-methylpiperidine …
Matched Description: … Antihistamines used in the treatment of allergy act by competing with histamine for H 1-receptor sites …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Sulfacytine is a short-acting sulfonamide. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism...
Approved
Matched Synonyms: … 1-ethyl N4-sulfanilylcytosin ... 1-ethyl-N-sulfanilylcytosine …
Matched Iupac: … 4-amino-N-(1-ethyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzene-1-sulfonamide …
Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential. The balance between potassium and sodium...
Approved
Investigational
Matched Synonyms: … potassium(1+) ... potassium(1+) ion …
Matched Iupac: … potassium(1+) ion …
Tesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing Hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia associated with antiretroviral therapy for HIV infection.
Approved
Investigational
Matched Synonyms: … GHRH(1-44) ... N-[(3E)-1-oxo-3-hexenyl]Somatoliberin (human pancreatic islet) …
Displaying drugs 51 - 75 of 10766 in total