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Displaying drugs 51 - 75 of 1397 in total
Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19)).
Investigational
Matched Synonyms: … a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein ... Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 receptor and
Matched Description: … Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of ... a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe …
Calcium carbimide, sold as the citrate salt, is an alcohol-sensitizing agent. Its effects are similar to the drug disulfiram (Antabuse) in that it interferes with the normal metabolism of alcohol by preventing the breakdown of the metabolic product acetaldehyde. Calcium carbimide was conceived as an alternative for the treatment of...
Approved
Withdrawn
Matched Synonyms: … Calcium carbimide ... calcium cyanamide ... carbimida calcica
Matched Name: … Calcium carbimide …
Matched Iupac: … calcium (azanidylenemethylidene)azanide …
Matched Description: … [A31516] This drug was developed by Lederle Cyanamid Canada Inc and approved for marketing in Canada ... Calcium carbimide, sold as the citrate salt, is an alcohol-sensitizing agent. ... The current status of calcium carbimide is cancelled post marketing.[L1113] …
Matched Salts name: … Citrated calcium carbimide …
Matched Categories: … calcium carbimide …
Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and ... the activity-related kringle-2 and serine protease domains of human tPA. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia ... , colestipol is still generally only employed as an adjunct therapy and the relatively physical nature …
Matched Categories: … Medications that reduce magnesium levels …
Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent...
Approved
Matched Synonyms: … Selenium Sulfide ... Selenium(IV) sulfide ... Selenium sulfide, micronized …
Matched Name: … Selenium Sulfide
Matched Description: … dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent children ... Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative ... Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic …
Matched Mixtures name: … Clease and Treat …
Matched Categories: … selenium sulfide
Matched Products: … Selenium Sulfide ... Selenium sulfide ... Meijer Medicated Selenium Sulfide Anti-Dandruff …
Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. The primary site of action of aluminum chlorohydrate is at the level of the stratum corneum layer, which is relatively near...
Approved
Matched Iupac: … dialuminium(3+) ion hydrate chloride pentahydroxide …
Matched Categories: … Astringents and Deodorants ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Jardins du Monde Indian Cotton Flower Antiperspirant Roll-On ... Jardins du Monde Laotion Lotus Flower Antiperspirant Roll-On ... Degree Shower Clean Aerosol Antiperspirant and Deodorant …
Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases ... PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
Approved
Matched Synonyms: … Alcohol anhydrous
Matched Description: … A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout ... It has bactericidal activity and is used often as a topical disinfectant. ... It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as …
Matched Mixtures name: … Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces ... Bite and Sting Relief Wipe ... Easy Care First Aid Kit - Outdoor and Travel …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … HiGeen Antiseptic Hand Sanitizer Gel With Vitamin Beads Blue Flowers With Silicon Holder ... HiGeen Antiseptic Hand Sanitizer Gel With Vitamin Beads Passion Flower With Silicon Holder ... Friuts and Flowers Clean Cotton Waterless Hand Sanitizer …
Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the...
Nutraceutical
Matched Synonyms: … Calcio ... Calcium, elemental ... Elemental calcium
Matched Name: … Calcium
Matched Iupac: … calcium
Matched Description: … Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. ... Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, ... The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. …
Matched Mixtures name: … Active Calcium Plus Magnesium, Vitamin D and Silicon ... Magnesium Chloride ... Calcium Magnesium Sulfur Silicon - Tab …
Matched Categories: … Phosphate Binder ... Phosphate Chelating Activity ... multivitamins and calcium ... Calcium-Regulating Hormones and Agents ... ascorbic acid (vit C) and calcium
Matched Products: … Great Calcium ... 7030 Calcium Gold ... Calcium
Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Description: … purified Factor VIII from human pooled blood and contains both A- and B-subunits, and [DB11607], which ... Moroctocog alfa is approved by Health Canada and by the European Medicines Agency for the control and ... prevention of hemorrhagic episodes and for routine and surgical prophylaxis in patients with hemophilia …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison...
Approved
Investigational
Matched Description: … and bone fractures later in life. ... B12, and an increased risk of developing hypomagnesemia and hypocalcemia which may contribute to osteoporosis ... gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and
Matched Mixtures name: … Naproxen and esomeprazole magnesium ... Naproxen and esomeprazole magnesium ... Naproxen and Esomeprazole Magnesium
Matched Salts name: … Esomeprazole magnesium trihydrate ... Esomeprazole sodium ... Esomeprazole magnesium ... Esomeprazole magnesium dihydrate …
Matched Categories: … Medications that reduce magnesium levels ... Alimentary Tract and Metabolism ... Antiinflammatory and Antirheumatic Products ... Omeprazole and enantiomer ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Esomeprazole Magnesium ... Berkley and Jensen Heartburn Treatment ... Foster and Thrive Acid Reducer …
Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …
Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (40 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) …
DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo …
Matched Description: … DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and
CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Synonyms: … Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue …
Matched Description: … ), a synthetic SP-C analogue, and a synthetic SP-B analogue. ... preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific ... IgG1 antibody inhibiting PD-L1 and CTLA-4 …
Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains...
Approved
Matched Description: … Allantoin is a substance that is endogenous to the human body and also found as a normal component of ... During exercise, the plasma allantoin concentration rapidly increases about two fold and remains elevated ... , in shampoos, lipsticks, anti-acne products, sun care products, and clarifying lotions [A32213]. …
Matched Mixtures name: … Aspiera Wound Care and Antiseptic ... Aspiera Wound Care and Antiseptic ... Terrasil Itch, Rash and Pain Relief …
Matched Categories: … Basic Ointments and Protectants ... Herbs and Natural Products …
Matched Products: … Vital Fluid II EGF and FGF Whitening Serum ... Ramosu The Witches Cream Pack Gold ... Original Power Whitening and Lineless Ampoule …
Aluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent and deodorant agent. It works by physically blocking eccrine sweat gland ducts .
Approved
Matched Description: … Aluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent and
Matched Mixtures name: … Lactovit DEODORANT AND ANTIPERSPIRANT INVISIBLE ANTISTAIN …
Matched Categories: … Chlorine Compounds …
Matched Products: … ESIKA FLOWERY Roll-On ... Fraicheur Verveine Antiperspirant and Deodorant Roll-ON ... Fraicheur The Vert Antiperspirant and Deodorant Roll-ON …
Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …
AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple myeloma.
Investigational
Matched Synonyms: … Humanized Bi-Specific Xmab(R) T Cell Recruiting Antibody Construct Directed Against Cd3 And Cd38 …
NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.
Investigational
Matched Synonyms: … lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger …
Matched Description: … 2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and
Linvoseltamab is an investigational bispecific antibody. It promotes the interaction of B-cell maturation antigen (BCMA) on multiple myeloma cells with CD3-expressing T cells.
Investigational
Matched Synonyms: … human IgG4-based anti-CD3 x anti-BCMA bispecific monoclonal antibody that binds to CD3 and BCMA …
GTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide the desired genetic correction.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus serotype rh79 (AAVrh.79) vectors: AAVrh79.TBG.M2PCSK9.WPRE.bGH and
Matched Description: … by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and
An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items...
Approved
Investigational
Matched Description: … sports equipment and shoes. ... An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy ... It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, …
Matched Mixtures name: … Oral Plan Antibacterial Mouthrinse With Fluoride ... Benzocaine and Triclosan ... Benzocaine and Triclosan …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … Orchid Cactus Flower and Mango ... Cactus Flower and Mango Antibacterial Gentle Foaming Hand Sp ... Cactus Flower and Mango Antibacterial Deep Cleansing Hand Sp …
Displaying drugs 51 - 75 of 1397 in total