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Displaying drugs 726 - 750 of 1938 in total
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Pitavastatin, also known as the brand name product Livalo, is a lipid-lowering drug belonging to the statin class of medications. By inhibiting the endogenous production of cholesterol within the liver, statins lower abnormal cholesterol and lipid levels and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively...
Approved
Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of interaction with sodium channels. Lacosamide was first approved by the European Commission in August 2008 and was later...
Approved
Milnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) and like many agents in this category was originally developed for and continues to be approved and indicated for the treatment of depression [F3928, F3934, A175786, A175951]. Furthermore, in 2009 the US FDA approved milnacipran for the additional indication of...
Approved
Investigational
Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local...
Approved
Vet approved
Matched Salts cas: … 6108-05-0
Matched Mixtures name: … ACT Kit (Accelerated COVID-19 Test Kit) ... ACAT SUK Kit (Accelerated COVID-19 Antibody Test Single Use Kit) …
Zinc oxide is an inorganic compound used in a number of manufacturing processes. It can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and first-aid tapes. It occurs naturally as the mineral zincite, but most zinc oxide is produced...
Approved
Matched Mixtures name: … Koh Gen Do Aqua Foundation PK-0 ... Se-Natal 19 ... Thrivite 19
Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and as an aid for smoking cessation. Bupropion exerts its pharmacological effects by weakly inhibiting the enzymes involved in the uptake...
Approved
Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Pramlintide is a relatively new adjunct treatment for diabetes (both type 1 and 2), developed by Amylin Pharmaceuticals. It is derived from amylin, a hormone that is released into the bloodstream, in a similar pattern as insulin, after a meal. Like insulin, amylin is deficient in individuals with diabetes.
Approved
Investigational
Matched Iupac: … -3-methylbutyl]carbamoyl}butyl]-2-[(2S,3R)-2-[(2S)-2-{[(4R,7S,10S,13S,16S,19R)-16-(carbamoylmethyl)-19
A compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]
Approved
Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Approved
Investigational
Matched Mixtures name: … Shiseido Sun Block Crm SPF 19 ... Laboratoire Remede Translucent Uv Coat Tint 0
Investigational
Matched Name: … TAS-108
Matched Iupac: … ,15R)-14-(2-{4-[(diethylamino)methyl]-2-methoxyphenoxy}ethyl)-9,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^ …
AMG 108 was investigated for use as an antirheumatic agent.
Investigational
Matched Name: … AMG 108
Matched Description: … AMG 108 was investigated for use as an antirheumatic agent. …
COVID-19 convalescent plasma is plasma collected from patients who have acquired and subsequently recovered from COVID-19 and which contains antibodies against the causative agent SARS-CoV-2. This investigational COVID-19 treatment is currently available through three main pathways: use in registered clinical trials, use through the expanded access COVID-19 protocol (21 CFR...
Investigational
Matched Synonyms: … Convalescent plasma (COVID-19) …
Matched Name: … COVID-19 convalescent plasma …
Matched Description: … from COVID-19 and which contains antibodies against the causative agent SARS-CoV-2. ... COVID-19 convalescent plasma is plasma collected from patients who have acquired and subsequently recovered ... [L14333] This investigational COVID-19 treatment is currently available through three main pathways: …
Matched Categories: … Experimental Unapproved Treatments for COVID-19
XAV-19 is an intravenous antibody-based treatment targeted towards SARS-CoV-2 and other coronaviruses[L16553,L16558]. The therapy concept is based on COVID-19 convalescent plasma. However, rather than using human plasma, XAV-19 is a heterologous swine glyco-humanized polyclonal antibody that targets the spike protein of SARS-CoV-2[L16553,L16558]. The therapy offers three beneficial effects: the ability...
Investigational
Matched Name: … XAV-19
Matched Description: … The therapy concept is based on [COVID-19 convalescent plasma]. ... XAV-19 is an intravenous antibody-based treatment targeted towards SARS-CoV-2 and other coronaviruses ... However, rather than using human plasma, XAV-19 is a heterologous swine glyco-humanized polyclonal antibody …
The KBP-201 COVID-19 Vaccine was developed by British American Tobacco’s (BAT) U.S. biotech subsidiary, Kentucky BioProcessing (KBP). KBP cloned COVID-19’s genetic sequence, identified a potential antigen, and then inserted it into tobacco plants for reproduction. Upon harvest, the antigens were purified, and these components underwent preclinical testing in animals. As...
Investigational
Matched Name: … KBP-COVID-19
Matched Description: … The KBP-201 COVID-19 Vaccine was developed by British American Tobacco’s (BAT) U.S. biotech subsidiary ... KBP cloned COVID-19’s genetic sequence, identified a potential antigen, and then inserted it into tobacco ... KBP is conducting a Phase 1/2 clinical trial to evaluate the safety and immunogenicity of KBP-COVID-19
ssCART-19 cells consist of autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a short hairpin RNA (shRNA) against interleukin-6 (IL-6).
Investigational
Matched Synonyms: … CAR)-T cells expressing a short hairpin RNA (shRNA) against interleukin-6 (IL-6) (also termed ssCART-19
Matched Name: … ssCART-19 cells …
Matched Description: … ssCART-19 cells consist of autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a …
19-Norandrostenedione refers to two steroid isomers that were once marketed as dietary supplements and mainly used by body builders. After 2005, 19-Norandrostenedione was regulated in the United States as a schedule III controlled substance, as well as banned from use in competitive sports by the World Anti-Doping Agency. In the...
Experimental
Illicit
Matched Name: … 19-norandrostenedione …
Matched Description: … 19-Norandrostenedione refers to two steroid isomers that were once marketed as dietary supplements and ... After 2005, 19-Norandrostenedione was regulated in the United States as a schedule III controlled substance ... In the body 19-norandrostenedione is rapidly metabolized into [nandrolone], also known as nortestosterone …
Covax-19™, a protein-based vaccine, was developed through partnership between APC and Vaxine. It uses an insect-cell-produced recombinant SARS-CoV-2 spike protein and Vaxine’s adjuvant, Advax-SM. This adjuvant is designed to circumvent high fevers, fatigue, and aches experienced with other vaccines using more traditional adjuvants. Covax-19™ was tested in animal studies, and...
Investigational
Matched Name: … Covax-19™ …
Matched Description: … the COVID-19 spike protein. ... Covax-19™, a protein-based vaccine, was developed through partnership between APC and Vaxine. ... Covax-19™ was tested in animal studies, and shown to achieve potent antibody and T-cell responses against …
Experimental
Matched Name: … Compound 19
The GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea . As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488].
Investigational
Matched Name: … GX-19 Vaccine …
Matched Description: … The GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea[A219758]. …
COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection is an intradermal injection currently being investigated in the clinical trial NCT03348670 (Discovery Stage (Proof-of-concept) COVID-19 Antigen Presentation Therapeutic Biologics (COVID-19--AP) (AP-TP-Bio)) .
Investigational
Matched Synonyms: … COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection ... COVID-19 Therapeutic Biologics - Spike-GM-CSF Protein Lactated Ringer's Injection …
Matched Name: … COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection …
Matched Description: … Presentation Therapeutic Biologics (COVID-19--AP) (AP-TP-Bio))[L31333]. ... COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection is an intradermal injection currently being ... investigated in the clinical trial NCT03348670 (Discovery Stage (Proof-of-concept) COVID-19 Antigen …
19-Nor-5-andorstenedione is a prohormone which has the potential to affect bodily levels of testosterone once metabolized in vivo. It is regulated in the United States as a schedule III controlled substance, and prohibited by the World Anti-Doping Agency for use in competitive sports.
Experimental
Illicit
Matched Name: … 19-Nor-5-androstenedione …
Matched Description: … 19-Nor-5-andorstenedione is a prohormone which has the potential to affect bodily levels of testosterone …
AV-COVID-19 is a vaccine composed of autologous dendritic cells loaded with SARS-CoV-2 antigens and with or without Granulocyte-macrophage colony-stimulating factor (GM-CSF). The vaccine is created from the receiving patients’ isolated peripheral blood monocytes. The monocytes are then differentiated in vitro into dendritic cells with IL-4 and GM-CSF, incubated with SARS-CoV-2...
Investigational
Matched Name: … AV-COVID-19
Matched Description: … AV-COVID-19 is a vaccine composed of autologous dendritic cells loaded with SARS-CoV-2 antigens and with …
As of July 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for the COVID-19 AP TP Vaccine for ‘proof of concept.’ The vaccine utilizes granulocyte macrophage-colony stimulating factor (GM-CSF), a cytokine known to enhance vaccine efficacy through prolongation of humoral and cell immunity.
Investigational
Matched Synonyms: … COVID-19 AP TP Vaccine ... COVID-19 Therapeutic Vaccine - Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection …
Matched Name: … COVID-19 Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection …
Matched Description: … 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for the COVID-19
Displaying drugs 726 - 750 of 1938 in total