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Displaying drugs 726 - 750 of 2642 in total
Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Description: … glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and
Matched Categories: … Alimentary Tract and Metabolism ... Prednisolone and Prodrugs ... Sex Hormones and Insulins ... prednisolone and mydriatics ... abiraterone and prednisolone …
Matched Products: … PREDNISOLON ACIS 5MG ... PREDNISOLON ACIS 10MG ... PREDNISOLON ACIS 20MG …
Experimental
Matched Name: … PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE
Pimasertib is under investigation in clinical trial NCT01378377 (Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus).
Investigational
Matched Synonyms: … N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide …
Matched Iupac: … N-[(2S)-2,3-dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]pyridine-4-carboxamide …
Matched Salts name: … Pimasertib hydrochloride
Matched Categories: … Nicotinic Acids ... Acids, Heterocyclic …
Investigational
Matched Synonyms: … 1h-indeno(2,1-b)pyridine-6-carbonitrile, 1-(1h-benzimidazol-6-ylcarbonyl)-2,3,4,4a,9,9a-hexahydro-, ( …
Investigational
Matched Synonyms: … 6-chloro-2-ethyl-n-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperdinyl)phenyl)methyl)-imidazo(1,2-a)pyridine ... Imidazo(1,2-a)pyridine-3-carboxamide, 6-chloro-2-ethyl-n-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperidinyl …
Matched Iupac: … 6-chloro-2-ethyl-N-[(4-{4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl}phenyl)methyl]imidazo[1,2-a]pyridine
Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.
Approved
Matched Synonyms: … 11-(1-Methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ... 6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
Matched Description: … those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and ... thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release …
Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Approved
Investigational
Matched Synonyms: … 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ... 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
Matched Description: … Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral ... Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter …
Matched Categories: … Loratadine and derivatives …
Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Matched Description: … [L11815] It has demonstrated superior activity compared to [fluocinonide][A190963] and was first described …
Matched Mixtures name: … Clobetasol Propionate 0.05% / Coal Tar 8% / Salicylic Acid 6% ... Ciclopirox Olamine 0.77% / Clobetasol Propionate 0.05% / Salicylic Acid 3%. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Clobetasol Propionate ANDA ... CLOBETASOL ACIS CREME ... CLOBETASOL ACIS SALBE …
Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. It is found in ophthalmic solutions used to reverse mydriasis after an eye examination.
Approved
Matched Synonyms: … 5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridine
Matched Salts name: … Dapiprazole hydrochloride
Matched Categories: … Antiglaucoma Preparations and Miotics …
Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout. Xanthine oxidase, or xanthine oxidoreductase (XOR), regulates purine metabolism, and inhibition of the enzyme results in efficacious reduction of serum urate levels. Xanthine oxidase inhibitors are classified into two groups; purine analogs such as...
Experimental
Matched Synonyms: … 4-(5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl)pyridine-2-carbonitrile …
Matched Iupac: … 4-[5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile …
Matched Description: … ineffective in reducing uric acid levels under recommended dosing regimens. ... and gout. ... ], and non-purine agents which includes topiroxostat. …
Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Approved
Investigational
Matched Synonyms: … 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester …
Matched Description: … It is an effective antihypertensive agent and differs from other calcium channel blockers in that it ... does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive. …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... enalapril and nitrendipine ... Calcium-Regulating Hormones and Agents …
Matched Products: … NITREN ACIS 20MG …
Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as...
Approved
Matched Description: … and reducing cough. ... It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing ... It was introduced into the market in 1963, and is widely available as an over-the-counter drug in many …
Matched Salts name: … Bromhexine hydrochloride
Matched Categories: … Cough and Cold Preparations …
Matched Products: … Bromhexine Hydrochloride
Experimental
Investigational
Matched Synonyms: … Enanthic acid ... Heptoic acid ... Heptanoic acid
Matched Name: … Heptanoic acid
Matched Iupac: … heptanoic acid
PD-169316 is a p38 MAP kinase inhibitor.
Investigational
Matched Synonyms: … Pyridine, 4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1h-imidazol-5-yl)- ... Pyridine, 4-(5-(4-fluorophenyl)-2-(4-nitrophenyl)-1h-imidazol-4-yl)- …
Matched Iupac: … 4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine
Experimental
Matched Synonyms: … Carballylic acid ... 3-carboxyglutaric acid ... β-carboxyglutaric acid
Matched Name: … Tricarballylic acid
Matched Iupac: … propane-1,2,3-tricarboxylic acid
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
Investigational
Matched Synonyms: … 2-(2-chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl-1H-pyrazolo[4,3-C]pyridine-3,6(2H,5H)-dione …
Matched Iupac: … 2-(2-chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl-1H,2H,3H,5H,6H-pyrazolo[4,3-c]pyridine-3,6-dione …
A α,β-unsaturated monocarboxylic acid that is ethene substituted by a carboxy group.
Experimental
Matched Synonyms: … acroleic acid ... 2-Propenoic acid ... Propenoic acid
Matched Name: … Acrylic Acid
Matched Iupac: … prop-2-enoic acid
Matched Description: … A α,β-unsaturated monocarboxylic acid that is ethene substituted by a carboxy group. …
Matched Categories: … Equipment and Supplies ... Acids, Acyclic ... Carboxylic Acids
Experimental
Matched Synonyms: … 1-ethanesulfonic acid ... Ethylsulfonic acid ... 2-ethanesulfonic acid
Matched Name: … Ethanesulfonic acid
Matched Iupac: … ethanesulfonic acid
Matched Categories: … Sulfur Acids ... Sulfonic Acids ... Alkanesulfonic Acids
A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
Approved
Matched Synonyms: … Palmitic Acid ... Hexadecoic acid ... Hexadecylic acid
Matched Name: … Palmitic Acid
Matched Iupac: … hexadecanoic acid
Matched Description: … A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids. …
Matched Salts name: … 16-chloropalmitic acid
Matched Categories: … Fatty Acids ... Palmitic Acids
Experimental
Matched Synonyms: … Tosic acid ... Tosylic acid ... 4-toluenesulfonic acid
Matched Name: … p-Toluenesulfonic acid
Matched Iupac: … 4-methylbenzene-1-sulfonic acid
Matched Categories: … Sulfur Acids ... Sulfonic Acids ... Arylsulfonic Acids
Ilex paraguariensis leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Mate Folium ... Mate Folium (Ilex Paraguariensis St. Hilaire) …
Zolpidem, also known as Ambien, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. It is aimed for use in patients with difficulties initiating sleep. This drug decreases the time to fall asleep (sleep latency), increases the...
Approved
Matched Synonyms: … N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamide …
Matched Description: … It is available in both immediate acting and extended release forms [FDA label], [F3802]. ... This drug decreases the time to fall asleep (sleep latency), increases the duration of sleep, and decreases ... In addition, zolpidem improves sleep quality in patients suffering from chronic insomnia and can show …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics ... gamma-Aminobutyric Acid-ergic Agonist ... gamma-Aminobutyric Acid A Receptor Positive Modulator …
Decanoic acid is a solid. This compound belongs to the straight chain fatty acids. These are fatty acids with a straight aliphatic chain. The proteins that decanoic acid targets include furin, octanoyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase 1, peptostreptococcal albumin-binding protein, and putative uncharacterized protein tcp14.
Experimental
Matched Synonyms: … Capric acid ... Decanoic acid ... n-capric acid
Matched Name: … Capric acid
Matched Iupac: … decanoic acid
Matched Description: … ] synthase 1, peptostreptococcal albumin-binding protein, and putative uncharacterized protein tcp14. ... Decanoic acid is a solid. This compound belongs to the straight chain fatty acids. ... These are fatty acids with a straight aliphatic chain. …
Matched Categories: … Fatty Acids
Experimental
Matched Synonyms: … 5-Phenylvaleric acid ... Phenylvaleric acid ... Phenylpentanoic acid
Matched Name: … 5-phenylpentanoic acid
Matched Iupac: … 5-phenylpentanoic acid
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem]
Experimental
Vet approved
Matched Synonyms: … atoxylic acid ... Arsanilic acid ... 4-arsanilic acid
Matched Name: … Arsanilic acid
Matched Iupac: … (4-aminophenyl)arsonic acid
Matched Description: … It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem] ... An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. …
Matched Categories: … Nucleic Acid Synthesis Inhibitors …
Displaying drugs 726 - 750 of 2642 in total