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Displaying drugs 726 - 750 of 2717 in total
Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor .
Approved
Investigational
Matched Iupac: … [(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
Matched Description: … Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and
Matched Mixtures name: … Benazepril Hydrochloride and Hydrochlorothiazide ... Benazepril Hydrochloride and Hydrochlorothiazide ... Benazepril Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Benazepril hydrochloride
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... benazepril and diuretics ... benazepril and amlodipine …
Matched Products: … Benazepril Hydrochloride ... Benazepril hydrochloride
Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.
Approved
Matched Synonyms: … 11-(1-Methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ... 6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
Matched Description: … those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and ... thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release …
A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Approved
Matched Mixtures name: … Prilocaine Hydrochloride with Epinephrine ... Lidocaine and Prilocaine ... Lidocaine and Prilocaine …
Matched Salts name: … Prilocaine hydrochloride
Matched Products: … Prilocaine Hydrochloride ... Dentsply 4% Prilocaine Hydrochloride Dental Injection …
Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Approved
Investigational
Matched Synonyms: … 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ... 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
Matched Description: … Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral ... Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter …
Matched Categories: … Loratadine and derivatives …
Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.
Approved
Matched Mixtures name: … Perphenazine and Amitriptyline Hydrochloride ... Perphenazine and Amitriptyline Hydrochloride ... Perphenazine and Amitriptyline Hydrochloride
Matched Salts name: … Amitriptyline hydrochloride
Matched Categories: … amitriptyline and psycholeptics ... Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Amitriptyline Hydrochloride ... Amitriptyline hydrochloride ... AMITRIPTYLINE HYDROCHLORIDE
A derivative of procaine with less CNS action.
Approved
Matched Salts name: … Procainamide hydrochloride
Matched Categories: … Benzamides and benzamide derivatives ... Acids, Carbocyclic ... Carboxylic Acids
Matched Products: … Procainamide Hydrochloride ... Procainamide Hydrochloride Injection USP …
A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Approved
Illicit
Matched Description: … A short-acting opioid anesthetic and analgesic derivative of fentanyl. ... It produces an early peak analgesic effect and fast recovery of consciousness. ... effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and
Matched Salts name: … Alfentanil hydrochloride
Matched Categories: … Fentanyl and fentanyl analogues …
Matched Products: … Alfentanil Hydrochloride
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Synonyms: … fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid ... -fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
Matched Iupac: … fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
Matched Description: … clinical studies to result in a 45.8% to 54.6% decreases in LDL cholesterol levels, which is about three-fold ... hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid ... referred to as "bad cholesterol"), and very low-density lipoprotein (VLDL). …
Matched Mixtures name: … Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe …
Matched Salts name: … Rosuvastatin calcium
Matched Categories: … rosuvastatin and acetylsalicylic acid ... Alimentary Tract and Metabolism ... rosuvastatin and valsartan ... rosuvastatin and ramipril ... rosuvastatin and amlodipine …
Matched Products: … Rosuvastatin Calcium ... Rosuvastatin calcium ... ROSUVASTATIN CALCIUM
Investigational
Matched Synonyms: … 1h-indeno(2,1-b)pyridine-6-carbonitrile, 1-(1h-benzimidazol-6-ylcarbonyl)-2,3,4,4a,9,9a-hexahydro-, ( …
An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Approved
Matched Salts name: … Midodrine hydrochloride
Matched Categories: … Adrenergic and Dopaminergic Agents …
Matched Products: … Midodrine Hydrochloride ... Midodrine hydrochloride
Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
Approved
Investigational
Matched Salts name: … Naratriptan hydrochloride
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … Naratriptan Hydrochloride
Investigational
Matched Synonyms: … 6-chloro-2-ethyl-n-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperdinyl)phenyl)methyl)-imidazo(1,2-a)pyridine ... Imidazo(1,2-a)pyridine-3-carboxamide, 6-chloro-2-ethyl-n-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperidinyl …
Matched Iupac: … 6-chloro-2-ethyl-N-[(4-{4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl}phenyl)methyl]imidazo[1,2-a]pyridine
Ropinirole, also known as ReQuip, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], . It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. In 2005, it was the first...
Approved
Investigational
Matched Description: … Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and ... offering a similar side effect profile and efficacy to previous formulations of ropinirole [A35711]. ... capsules of ropinirole were approved, allowing for less frequent dosing, therefore increased compliance, and
Matched Salts name: … Ropinirole Hydrochloride
Matched Products: … Ropinirole Hydrochloride ... ROPINIROL ACIS 2MG …
Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Matched Description: … [L11815] It has demonstrated superior activity compared to [fluocinonide][A190963] and was first described …
Matched Mixtures name: … Clobetasol Propionate 0.05% / Coal Tar 8% / Salicylic Acid 6% ... Ciclopirox Olamine 0.77% / Clobetasol Propionate 0.05% / Salicylic Acid 3%. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Clobetasol Propionate ANDA ... CLOBETASOL ACIS CREME ... CLOBETASOL ACIS SALBE …
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear,...
Approved
Investigational
Matched Description: … It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, ... mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and ... it may have direct actions on calcium channels. …
Matched Salts name: … Papaverine hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... Papaverine and Derivatives ... Genito Urinary System and Sex Hormones …
Matched Products: … Papaverine Hydrochloride ... PAPAVERINE HYDROCHLORIDE ... Papaverine Hydrochloride Injection USP …
Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched Synonyms: … Acetic acid (2S,3S)-5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][ …
Matched Description: … Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. ... into cardiac and vascular smooth muscle during depolarization. ... under various brand names with Cardizem and Tiazac being the most common ones. …
Matched Salts name: … Diltiazem hydrochloride
Matched Categories: … Calcium-Regulating Hormones and Agents ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Calcium Channel Blockers ... Calcium Channel Blockers (Nondihydropyridine) ... Miscellaneous Calcium-channel Blocking Agents …
Matched Products: … Diltiazem Hydrochloride ... Diltiazem hydrochloride ... DILTIAZEM HYDROCHLORIDE
Experimental
Investigational
Matched Synonyms: … Enanthic acid ... Heptoic acid ... Heptanoic acid
Matched Name: … Heptanoic acid
Matched Iupac: … heptanoic acid
Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout. Xanthine oxidase, or xanthine oxidoreductase (XOR), regulates purine metabolism, and inhibition of the enzyme results in efficacious reduction of serum urate levels. Xanthine oxidase inhibitors are classified into two groups; purine analogs such as...
Experimental
Matched Synonyms: … 4-(5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl)pyridine-2-carbonitrile …
Matched Iupac: … 4-[5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile …
Matched Description: … ineffective in reducing uric acid levels under recommended dosing regimens. ... and gout. ... ], and non-purine agents which includes topiroxostat. …
Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Description: … uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation. ... and it does not cause endometrial proliferation. ... generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and
Matched Salts name: … Raloxifene Hydrochloride
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Raloxifene Hydrochloride ... Raloxifene hydrochloride
Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Approved
Investigational
Matched Synonyms: … 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester …
Matched Description: … It is an effective antihypertensive agent and differs from other calcium channel blockers in that it ... does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive. ... Nitrendipine is a calcium channel blocker with marked vasodilator action. …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... enalapril and nitrendipine ... Calcium Channel Blockers ... Selective Calcium Channel Blockers With Mainly Vascular Effects …
Matched Products: … NITREN ACIS 20MG …
Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.[Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy.[Label] Antagonism of these receptors leads to relaxation of smooth muscle in...
Approved
Investigational
Matched Description: … in the prostate and bladder, where these receptors are most common. ... Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect ... [Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. …
Matched Mixtures name: … Dutasteride and tamsulosin hydrochloride ... Dutasteride and Tamsulosin Hydrochloride ... Dutasteride and tamsulosin hydrochloride
Matched Salts name: … Tamsulosin hydrochloride
Matched Categories: … tamsulosin and tadalafil ... tamsulosin and dutasteride ... tamsulosin and solifenacin ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Tamsulosin Hydrochloride ... Tamsulosin hydrochloride ... TAMSULOSIN HYDROCHLORIDE
Sotalol is a methanesulfonanilide developed in 1960. It was the first of the class III anti arrhythmic drugs. Sotalol was first approved as an oral tablet on 30 October 1992. A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous injection indicated for life threatening...
Approved
Matched Description: … [L6334] A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous ... injection indicated for life threatening ventricular arrhythmias and maintaining normal sinus rhythm …
Matched Salts name: … Sotalol hydrochloride
Matched Categories: … sotalol and acetylsalicylic acid ... Beta Blocking Agents and Thiazides ... sotalol and thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides …
Matched Products: … Sotalol Hydrochloride ... Sotalol hydrochloride ... Sotalol Hydrochloride AF …
Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. It is found in ophthalmic solutions used to reverse mydriasis after an eye examination.
Approved
Matched Synonyms: … 5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridine
Matched Salts name: … Dapiprazole hydrochloride
Matched Categories: … Antiglaucoma Preparations and Miotics …
Colesevelam is a bile acid sequestrant. Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in the blood. It works by binding bile acids in the intestine. Bile acids are made when cholesterol is broken...
Approved
Matched Description: … Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce ... the amount of cholesterol and certain fatty substances in the blood. ... Colesevelam is a bile acid sequestrant. …
Matched Salts name: … Colesevelam hydrochloride
Matched Categories: … Bile Acid Sequestrants ... Bile-acid Binding Activity …
Matched Products: … Colesevelam Hydrochloride ... Colesevelam hydrochloride
Experimental
Matched Synonyms: … Carballylic acid ... 3-carboxyglutaric acid ... β-carboxyglutaric acid
Matched Name: … Tricarballylic acid
Matched Iupac: … propane-1,2,3-tricarboxylic acid
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
Displaying drugs 726 - 750 of 2717 in total