Displaying drugs 726 - 750 of 797 in total
Cagrilintide
Cagrilintide is under investigation in clinical trial NCT06221969 (A Research Study to See How Much Cagrisema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor).
Investigational
Matched Synonyms: … L-γ-glutamyl-L-lysyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-leucyl-L-arginyl-L-histidyl …
Matched Description: … investigation in clinical trial NCT06221969 (A Research Study to See How Much Cagrisema Lowers Blood Sugar and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … investigation in clinical trial NCT06221969 (A Research Study to See How Much Cagrisema Lowers Blood Sugar and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Irinotecan
Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Synonyms: … Irinotecan lactone …
Matched Description: … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376] ... irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … IRINOTEL 40 MG/2 ML IV INFUZYON ICIN KON. COZ. ICEREN FLAKON ... IRINOTEL 100 MG/5 ML IV INFUZYON ICIN KON. COZ. ICEREN FLAKON ... İRİTEC 40 MG/2 ML IV INFUZYON ICIN KON. COZ. ICEREN FLAKON, 1 FLAKON …
Matched Description: … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376] ... irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … IRINOTEL 40 MG/2 ML IV INFUZYON ICIN KON. COZ. ICEREN FLAKON ... IRINOTEL 100 MG/5 ML IV INFUZYON ICIN KON. COZ. ICEREN FLAKON ... İRİTEC 40 MG/2 ML IV INFUZYON ICIN KON. COZ. ICEREN FLAKON, 1 FLAKON …
2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine
Experimental
Matched Name: … 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine …
Matched Iupac: … 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine …
Matched Iupac: … 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine …
Lovastatin
Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus. Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid...
Approved
Investigational
Matched Synonyms: … 2β,6α-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone …
Matched Description: … Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite ... belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and ... studies to significantly reduce the risk of development of CVD and all-cause mortality. …
Matched Categories: … lovastatin and nicotinic acid …
Matched Description: … Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite ... belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and ... studies to significantly reduce the risk of development of CVD and all-cause mortality. …
Matched Categories: … lovastatin and nicotinic acid …
N-({6-[(4-CYANOBENZYL)OXY]NAPHTHALEN-2-YL}SULFONYL)-D-GLUTAMIC ACID
Experimental
Matched Name: … N-({6-[(4-CYANOBENZYL)OXY]NAPHTHALEN-2-YL}SULFONYL)-D-GLUTAMIC ACID …
N~3~-[3-(1H-INDOL-6-YL)BENZYL]PYRIDINE-2,3-DIAMINE
Experimental
Matched Name: … N~3~-[3-(1H-INDOL-6-YL)BENZYL]PYRIDINE-2,3-DIAMINE …
Matched Iupac: … N3-{[3-(1H-indol-6-yl)phenyl]methyl}pyridine-2,3-diamine …
Matched Iupac: … N3-{[3-(1H-indol-6-yl)phenyl]methyl}pyridine-2,3-diamine …
1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE
Experimental
Matched Name: … 1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE …
Matched Iupac: … 1-(2-nitrobenzenesulfonyl)-1H-pyrrolo[3,2-b]pyridine-6-carboxamide …
Matched Iupac: … 1-(2-nitrobenzenesulfonyl)-1H-pyrrolo[3,2-b]pyridine-6-carboxamide …
Testolactone
An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.
Approved
Investigational
Matched Synonyms: … 13-hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid δ-lactone …
Matched Description: … An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer …
Matched Description: … An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer …
Bamocaftor
Bamocaftor (VX-659) is under investigation in clinical trial NCT03224351 (A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis).
Investigational
Matched Synonyms: … 6-[3-[2-[1-(trifluoromethyl)cyclopropyl]ethoxy]pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine …
Matched Iupac: … -{2-[1-(trifluoromethyl)cyclopropyl]ethoxy}-1H-pyrazol-1-yl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine …
Matched Description: … Bamocaftor (VX-659) is under investigation in clinical trial NCT03224351 (A Study Evaluating the Safety and …
Matched Iupac: … -{2-[1-(trifluoromethyl)cyclopropyl]ethoxy}-1H-pyrazol-1-yl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine …
Matched Description: … Bamocaftor (VX-659) is under investigation in clinical trial NCT03224351 (A Study Evaluating the Safety and …
N-({6-[(4-CYANO-2-FLUOROBENZYL)OXY]NAPHTHALEN-2-YL}SULFONYL)-D-GLUTAMIC ACID
Experimental
Matched Name: … N-({6-[(4-CYANO-2-FLUOROBENZYL)OXY]NAPHTHALEN-2-YL}SULFONYL)-D-GLUTAMIC ACID …
N~3~-[3-(5-METHOXYPYRIDIN-3-YL)BENZYL]PYRIDINE-2,3-DIAMINE
Experimental
Matched Name: … N~3~-[3-(5-METHOXYPYRIDIN-3-YL)BENZYL]PYRIDINE-2,3-DIAMINE …
Matched Iupac: … N3-{[3-(5-methoxypyridin-3-yl)phenyl]methyl}pyridine-2,3-diamine …
Matched Iupac: … N3-{[3-(5-methoxypyridin-3-yl)phenyl]methyl}pyridine-2,3-diamine …
Methoxsalen
A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation.
Approved
Matched Synonyms: … 6-hydroxy-7-methoxy-5-benzofuranacrylic acid δ-lactone …
Matched Categories: … Indicators and Reagents …
Matched Categories: … Indicators and Reagents …
Methapyrilene
Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
Withdrawn
Matched Synonyms: … 2-[[2-(Dimethylamino)ethyl]-2-thenylamino]pyridine …
Matched Description: … Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979. …
Matched Categories: … Hypnotics and Sedatives …
Matched Description: … Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979. …
Matched Categories: … Hypnotics and Sedatives …
Solnatide
Solnatide has been used in trials studying the treatment of Acute Lung Injury.
Investigational
Matched Synonyms: … L-Cysteine, L-cysteinylglycyl-L-glutaminyl-L-arginyl-L-alpha-glutamyl-L-threonyl-L-prolyl-L-alpha-glutamylglycyl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-lysyl-L-prolyl-L-tryptophyl-L-tyrosyl …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ulviprubart
Investigational
Matched Synonyms: … CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 (CH1 R120>K …
MPT-0L055
Investigational
Matched Synonyms: … 4-(((3-chloro-1,4-dioxo-1,4 dihydronaphthalen-2-yl)amino)methyl)-n-(pyridine-3-yl)benzamide …
AVA-6000
Investigational
Matched Synonyms: … dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl]oxy}oxan-4-yl)carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]pyridine …
Nerinetide
Na 1 is under investigation in clinical trial NCT00728182 (Evaluating Neuroprotection in Aneurysm Coiling Therapy).
Investigational
Matched Synonyms: … L-TYROSYLGLYCYL-L-ARGINYL-L-LYSYL-L-LYSYL-L-ARGINYL-L-ARGINYL-L-GLUTAMINYL-L-ARGINYL-L-ARGINYL-L-ARGINYL-L-LYSYL-L-LEUCYL-L-SERYL-L-SERYL-L-ISOLEUCYL-L ... L-VALINE, L-TYROSYLGLYCYL-L-ARGINYL-L-LYSYL-L-LYSYL-L-ARGINYL-L-ARGINYL-L-GLUTAMINYL-L-ARGINYL-L-ARGINYL-L-ARGINYL-L-LYSYL-L-LEUCYL-L-SERYL-L-SERYL-L-ISOLEUCYL-L …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Froniglutide
Glymera is under investigation in clinical trial NCT01658501 (Phase 2b Multicenter, Randomized, Double-blind, Placebo- and Active-controlled, Parallel-group Study to Assess the PD Response and Safety of Three Dose Levels of (PB1023) Injection Following 20 Weeks of Weekly SC Dosing in Adults With T2DM).
Investigational
Matched Synonyms: … L-Histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryp …
Matched Description: … investigation in clinical trial NCT01658501 (Phase 2b Multicenter, Randomized, Double-blind, Placebo- and ... Active-controlled, Parallel-group Study to Assess the PD Response and Safety of Three Dose Levels of …
Matched Description: … investigation in clinical trial NCT01658501 (Phase 2b Multicenter, Randomized, Double-blind, Placebo- and ... Active-controlled, Parallel-group Study to Assess the PD Response and Safety of Three Dose Levels of …
Nadide
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
Experimental
Matched Synonyms: … Pyridine, nucleotide diphosphate …
Matched Description: … electron carrier by being alternately oxidized (NAD+) and reduced (NADH). ... It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … electron carrier by being alternately oxidized (NAD+) and reduced (NADH). ... It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …
Letrozole
Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.[A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affect cortisol, aldosterone, and thyroxine. Letrozole was granted FDA approval on 25 July 1997.
Approved
Investigational
Matched Description: … ], meaning it does not significantly affect cortisol, aldosterone, and thyroxine. ... [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Zinda-letrozole …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Zinda-letrozole …
Folitixorin
Investigational
Matched Synonyms: … L-glutamic acid, n-(4-(3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo(1,5-f)pteridin-8(9h)-yl)benzoyl)- …
Matched Categories: … Enzymes and Coenzymes …
Matched Categories: … Enzymes and Coenzymes …
2-(Oxalyl-Amino)-4,5,6,7-Tetrahydro-Thieno[2,3-C]Pyridine-3-Carboxylic Acid
Experimental
Matched Name: … 2-(Oxalyl-Amino)-4,5,6,7-Tetrahydro-Thieno[2,3-C]Pyridine-3-Carboxylic Acid …
Matched Iupac: … 2-(carboxyformamido)-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylic acid …
Matched Iupac: … 2-(carboxyformamido)-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylic acid …
Pralatrexate
Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Synonyms: … N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid …
Matched Description: … lung cancer, breast cancer, and bladder cancer. ... higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and ... [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … lung cancer, breast cancer, and bladder cancer. ... higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and ... [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Brompheniramine
Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Approved
Matched Synonyms: … 2-(p-bromo-α-(2-dimethylaminoethyl)benzyl)pyridine …
Matched Description: … Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria. …
Matched Mixtures name: … Up and Up Childrens Cold and Cough ... Runny Nose and Cough ... Daytime Cold and Cough and NightTime Cold and Congestion Childrens …
Matched Description: … Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria. …
Matched Mixtures name: … Up and Up Childrens Cold and Cough ... Runny Nose and Cough ... Daytime Cold and Cough and NightTime Cold and Congestion Childrens …
Displaying drugs 726 - 750 of 797 in total