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Displaying drugs 751 - 775 of 5334 in total
A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
Approved
Vet approved
Matched Description: … A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. ... Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the ... mechanisms of its therapeutic effects are not clear. …
Matched Salts cas: … 59-97-2 …
Matched Salts name: … Tolazoline hydrochloride
Matched Categories: … Topical Products for Joint and Muscular Pain ... Adrenergic alpha-Antagonists ... Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Priscoline hydrochloride
Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body. It is on the World Health Organization Model List of Essential Medicines. Edetate calcium disodium was granted FDA approval on 16 July 1953.
Approved
Matched Synonyms: … Edetic acid calcium disodium salt …
Matched Description: … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores …
Matched Categories: … Diet, Food, and Nutrition ... Acids, Acyclic ... Carboxylic Acids ... Compounds used in a research, industrial, or household setting …
Matched Products: … Calcium Edetate de Sodium
A derivative of procaine with less CNS action.
Approved
Matched Description: … A derivative of procaine with less CNS action. …
Matched Salts name: … Procainamide hydrochloride
Matched Categories: … Benzamides and benzamide derivatives ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers ... Acids, Carbocyclic ... Carboxylic Acids
Matched Products: … Procainamide-500 Cap 500mg ... Procainamide Hydrochloride ... Procainamide Hydrochloride Injection USP …
Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone...
Approved
Investigational
Matched Synonyms: … 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran …
Matched Description: … indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and ... Because of its ability to cause serious toxicity and possibly death, amiodarone use should be reserved ... Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. …
Matched Salts name: … Amiodarone hydrochloride
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Sodium Channel Blockers ... alpha-Galactosidase, antagonists & inhibitors ... BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index …
Matched Products: … Ava-amiodarone ... AMIODARON AL 200 ... Amiodarone Hydrochloride
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Approved
Matched Synonyms: … 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]- …
Matched Iupac: … ]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido …
Matched Description: … It attains high serum levels and is excreted quickly via the urine. ... A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial …
Matched Mixtures name: … CEFAMEZIN 500 MG IM ENJEKTABL TOZ İÇEREN FLAKON, 1 ADET …
Matched Salts name: … Cefazolin sodium
Matched Categories: … Thiazines
Matched Products: … Cefazolin Sodium ... CEFAZOLIN SODIUM ... CEFAZOLINA SODICO 1 G …
Experimental
Matched Synonyms: … Phosphoric acid, magnesium salt (2:3) ... Magnesium phosphate (3:2) ... Trimagnesium phosphate
Matched Name: … Magnesium phosphate
Matched Salts name: … Magnesium phosphate pentahydrate ... Magnesium phosphate dibasic trihydrate …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... magnesium phosphate ... Acids ... Acids, Noncarboxylic …
Approved
Matched Synonyms: … 1,2-dipalmitoyl-sn-glycero-3-phosphorylglycerol sodium salt …
Matched Name: … Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol) …
Matched Iupac: … sodium (2R)-1-[(2,3-dihydroxypropyl phosphono)oxy]-3-(hexadecanoyloxy)propan-2-yl hexadecanoate …
Experimental
Matched Synonyms: … Xylitol 5-phosphate ... Xylitol 5-P …
Matched Name: … L-xylitol 5-phosphate
Matched Iupac: … {[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]oxy}phosphonic acid
Matched Categories: … Sugar Phosphates
Tiagabine is an anti-convulsive medication. It is also used in the treatment for panic disorder as are a few other anticonvulsants. Though the exact mechanism by which tiagabine exerts its effect on the human body is unknown, it does appear to operate as a selective GABA reuptake inhibitor.
Approved
Investigational
Matched Iupac: … (3R)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-en-1-yl]piperidine-3-carboxylic acid
Matched Description: … It is also used in the treatment for panic disorder as are a few other anticonvulsants. ... Tiagabine is an anti-convulsive medication. ... a selective GABA reuptake inhibitor. …
Matched Salts cas: … 145821-59-6 …
Matched Salts name: … Tiagabine hydrochloride
Matched Categories: … Nipecotic Acid and Derivatives ... Acids, Heterocyclic ... Fatty Acid Derivatives …
Matched Products: … Tiagabine Hydrochloride
A long-acting beta-2-adrenergic receptor agonist. It is a potent bronchodilator that may be administered orally or by aerosol inhalation.
Approved
Investigational
Matched International brands: … Pro-Air
Matched Iupac: … 8-hydroxy-5-[(1S,2R)-1-hydroxy-2-[(propan-2-yl)amino]butyl]-1,2-dihydroquinolin-2-one …
Matched Description: … A long-acting beta-2-adrenergic receptor agonist. ... It is a potent bronchodilator that may be administered orally or by aerosol inhalation. …
Matched Salts name: … Procaterol hydrochloride ... Procaterol hydrochloride hemihydrate …
Matched Products: … PROCATEROL HYDROCHLORIDE HEMIHYDRATE ... CATEROL 50 ... Pro-air Aerosol 10mcg/aem
Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched International brands: … Incoril AP
Matched Synonyms: … Acetic acid (2S,3S)-5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][ ... 4(5H)-one ... (+)-cis-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H) …
Matched Iupac: … (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3- …
Matched Description: … Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. ... , and as an anti-anginal agent [L6289] for the management of cardiovascular conditions such as hypertension ... smooth muscle and [verapamil] that directly acts on the heart muscle, diltiazem displays an intermediate …
Matched Salts cas: … 33286-22-5
Matched Salts name: … Diltiazem hydrochloride
Matched Categories: … Calcium-Regulating Hormones and Agents ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Diltiazem Hydrochloride ... Diltiazem hydrochloride ... DILTIAZEM HYDROCHLORIDE
Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Synonyms: … 10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine ... 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine …
Matched Description: … TCAs also block histamine H1 receptors, α1-adrenergic receptors and muscarinic ... and clomipramine. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. …
Matched Salts cas: … 113-52-0 …
Matched Salts name: … Imipramine hydrochloride
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists …
Matched Products: … Imipramine Hydrochloride ... มินาพีน 50 ... Apo-imipramine …
Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Synonyms: … 1,3-Dimethyl-5-adamantanamine …
Matched Description: … and excessive stimulation in Alzheimer's Disease [T556]. ... doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and ... It is different from many other Alzheimer's Disease medications, as it works by a different mechanism …
Matched Salts cas: … 41100-52-1 …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Salts name: … Memantine hydrochloride
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium ... Excitatory Amino Acid Antagonists ... Drugs that are Mainly Renally Excreted …
Matched Products: … MEMANTINE HYDROCHLORIDE TABLETS 5 MG MEIJI ... MEMANTINE HYDROCHLORIDE OD TABLETS 5 MG MEIJI ... Memantine Hydrochloride
Experimental
Matched Synonyms: … L-alpha-Amino-delta-hydroxyvaleric acid ... 5-Hydroxy-2-aminovaleric acid ... (S)-5-Hydroxynorvaline …
Matched Iupac: … (2S)-2-amino-5-hydroxypentanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … PMP-hydroxyisoxazole, pyridoxamine-5-phosphate-hydroxyisoxazole …
Matched Iupac: … acid ... [(5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methoxy]phosphonic …
A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Approved
Illicit
Matched Description: … A sympathomimetic agent with properties similar to dextroamphetamine. …
Matched Salts name: … Benzphetamine hydrochloride
Matched Categories: … Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists …
Matched Products: … Benzphetamine Hydrochloride
Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their...
Approved
Vet approved
Matched Synonyms: … 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine ... 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine …
Matched Iupac: … 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine …
Matched Description: … synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of urinary ... the synthesis of bacterial DNA and ultimately continued bacterial survival. ... L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and
Matched Mixtures name: … .)/5 ML. ... TRIMETOPRIMA 80/5ML + SULFAMETOXAZOL400/5ML SUSPENSION ... TRIMETOPRIMA 40 MG/5 ML SULFAMETOXAZOL 200MG/5 ML SUSPENSION …
Matched Salts name: … Trimethoprim hydrochloride
Matched Categories: … isoniazid, sulfamethoxazole, trimethoprim and pyridoxine ... Folic Acid Antagonists ... Trimethoprim and Derivatives ... sulfamoxole and trimethoprim ... Sulfonamides and trimethoprim …
Matched Products: … TRIMPEX trimethoprim hydrochloride
Experimental
Matched Synonyms: … (alphaS)-alpha-(((5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl)oxy)methyl)benzeneethanamine …
Matched Name: … A-674563 …
Matched Iupac: … (2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]oxy}-3-phenylpropan-2-amine …
Nalmefene, a 6-methylene analogue of naltrexone, is an opioid receptor antagonist. It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence. Nalmefene...
Approved
Investigational
Withdrawn
Matched Iupac: … (1S,5R,13S,17S)-4-(cyclopropylmethyl)-14-methylidene-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0 …
Matched Description: … [L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist ... Nalmefene, a 6-methylene analogue of [naltrexone], is an opioid receptor antagonist. ... at the kappa (κ)-opioid receptor. …
Matched Salts cas: … 1228646-70-5
Matched Salts name: … Nalmefene hydrochloride ... Nalmefene hydrochloride dihydrate …
Matched Categories: … Drugs that are Mainly Renally Excreted …
Matched Products: … Nalmefene Hydrochloride
Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Matched Description: … [label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. ... Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor. ... pain, Generalized Anxiety disorder, osteoarthritis, and stress incontinence. …
Matched Salts name: … Duloxetine hydrochloride
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Drugs that are Mainly Renally Excreted …
Matched Products: … Duloxetine hydrochloride ... Duloxetine Hydrochloride 20 mg ... Duloxetine Hydrochloride
Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.
Approved
Matched Synonyms: … Dipotassium acid phosphate ... Phosphoric acid, dipotassium salt ... Phosphoric acid, potassium salt (1:2) …
Matched Name: … Dipotassium phosphate
Matched Iupac: … dipotassium hydrogen phosphate
Matched Description: … Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive ... as a source of phosphorus and potassium as well as a buffering agent. …
Matched Mixtures name: … Ionosol B and Dextrose ... Salivart Aer ... ELETTROLITICA DI REINTEGRAZIONE CON GLUCOSIO E SODIO GLUCONATO FKI …
Matched Categories: … Phosphate salts ... Compounds used in a research, industrial, or household setting ... Acids ... Acids, Noncarboxylic ... Phosphoric Acids
Methanesulfonyl Fluoride has been used in trials studying the treatment of Safety.
Investigational
Matched Name: … Methanesulfonyl Fluoride
Matched Iupac: … methanesulfonyl fluoride
Matched Description: … Methanesulfonyl Fluoride has been used in trials studying the treatment of Safety. …
Investigational
Matched Synonyms: … Pentaazaacenaphthylene-5' phosphate ester ... -D-RIBOFURANOSYL-1,4,5,6,8-PENTAAZAACENAPHTHYLENE 5'-(DIHYDROGEN PHOSPHATE) ... Triciribine phosphate
Matched Name: … Triciribine phosphate
Matched Iupac: … pentaen-2-yl}-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid ... {[(2R,3S,4R,5R)-5-{5-amino-7-methyl-2,6,7,9,11-pentaazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,5,8,10- …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Approved
Matched Synonyms: … 2-Methyl-alpha-propylaminopropionanilide ... alpha-n-Propylamino-2-methylpropionanilide ... o-Methyl-alpha-propylaminopropionanilide …
Matched Description: … (From AMA Drug Evaluations Annual, 1992, p165) ... A local anesthetic that is similar pharmacologically to lidocaine. …
Matched Mixtures name: … Prilocaine Hydrochloride with Epinephrine ... Lidocaine and Prilocaine ... Lidocaine and Prilocaine …
Matched Salts name: … Prilocaine hydrochloride
Matched Products: … Prilocaine Hydrochloride ... PRESTIGE® PRILOCAINA CLORHIDRATO AL 4% ... Dentsply 4% Prilocaine Hydrochloride Dental Injection …
Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Description: … effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation ... and it does not cause endometrial proliferation. ... However, it has a negligible effect on altering the development and progression of breast cancer itself …
Matched Salts name: … Raloxifene Hydrochloride
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Raloxifene Hydrochloride ... Raloxifene hydrochloride ... Apo-raloxifene …
Displaying drugs 751 - 775 of 5334 in total