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Displaying drugs 776 - 800 of 1134 in total

FM-VP4

FM-VP4, is a novel hydrophilic phytostanol analogue representing a new class in cholesterol-lowering drugs called cholesterol absorption inhibitors. FM-VP4 has been shown to inhibit cholesterol absorption and to lower plasma LDL-cholesterol and total cholesterol in a broad range of animal species. Additional experiments suggest that FM-VP4 can reduce plasma LDL...
Investigational
Matched Synonyms: … Disodium ascorbyl phytostanol phosphates …
Matched Description: … FM-VP4 has been shown to inhibit cholesterol absorption and to lower plasma LDL-cholesterol and total ... levels, reduce weight gain and exert a anti-atherosclerosis effect. ... Additional experiments suggest that FM-VP4 can reduce plasma LDL cholesterol levels and triglyceride …

Ibandronate

Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid.[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA...
Approved
Investigational
Matched Description: … [A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis. ... third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and …
Matched Salts name: … Ibandronate sodium …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... ibandronic acid and colecalciferol …
Matched Products: … Ibandronate Sodium ... Ibandronate sodium ... Bonviva Pre-Filled Syringe 3mg/3ml …

L-xylitol 5-phosphate

Experimental
Matched Synonyms: … Xylitol 5-phosphate …
Matched Name: … L-xylitol 5-phosphate …
Matched Categories: … Sugar Phosphates …

Tedizolid phosphate

Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Synonyms: … Tedizolid phosphate ... Torezolid phosphate ... fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate …
Matched Name: … Tedizolid phosphate …
Matched Description: … ) and is generally more effective and more tolerable than [linezolid]. ... such as methicillin-resistant _Staphylococcus aureus_, vancomycin-resistant _Enterococcus faecium_, and ... Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist Pharmaceuticals as tedizolid phosphate …

Acetylcholine

A neurotransmitter. Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. It is generally not used as an administered drug because it is broken down very rapidly by cholinesterases,...
Approved
Investigational
Matched Description: … autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and …
Matched Salts name: … Acetylcholine chloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Miochol E Acetylcholine Chloride Oph Soln …

Pentobarbital

A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA...
Approved
Investigational
Vet approved
Matched Description: … agent and is usually given orally. ... A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) …
Matched Salts name: … Pentobarbital Sodium …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Nembutal Sodium ... Pentobarbital Sodium ... Nembutal Sodium Cap 100mg …

Glycerol 2-phosphate

Experimental
Matched Synonyms: … 1,3-Hydroxy-2-propyl dihydrogen phosphate ... 1,2,3-Propanetriol, 2-(dihydrogen phosphate) …
Matched Name: … Glycerol 2-phosphate …
Matched Categories: … Sugar Phosphates …

Butabarbital

Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.[A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety.[A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. Its short duration of action...
Approved
Illicit
Matched Description: … [A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Salts name: … Butabarbital sodium …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Butisol Sodium ... Butisol Sodium Tab 30mg ... Butisol Sodium Tab 15mg …

Amobarbital

A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
Approved
Illicit
Matched Description: … A barbiturate with hypnotic and sedative properties (but not antianxiety). ... Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with …
Matched Salts name: … Amobarbital sodium …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Amytal Sodium ... Amytal Sodium 500mg ... Amytal Sodium Cap 60mg …

D-erythrose 4-phosphate

Experimental
Matched Synonyms: … Erythose-4-phosphate …
Matched Name: … D-erythrose 4-phosphate …

beta-D-glucose 6-phosphate

Experimental
Matched Synonyms: … β-D-glucose 6-phosphate ... beta-D-glucose-6-phosphate ... beta-D-glucose 6-(dihydrogen phosphate) …
Matched Name: … beta-D-glucose 6-phosphate …

Sulfamoxole

Sulfamoxole is an antibacterial in the sulfonamide class.
Experimental
Matched International brands: … Sulfuno …
Matched Categories: … Sulfonamides and trimethoprim ... sulfamoxole and trimethoprim ... Sulfur Compounds …

Dimethyl sulfoxide

A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during cryopreservation. Dimethyl sulfoxide shows a range of pharmacological activity including...
Approved
Vet approved
Matched Synonyms: … Dimethyl sulfur oxide …
Matched Description: … Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation …
Matched Categories: … Genito Urinary System and Sex Hormones ... Topical Products for Joint and Muscular Pain ... Sulfur Compounds …

Lipegfilgrastim

Lipegfilgrastim, previously known as XM22, is a pegylated, recombinant granulocyte colony-stimulating factor (G-CSF) that was synthetized using a highly site-specific glycoPEGylation technology . It is used as an alternate to DB00019 for prophylactic use in cancer patients receiving chemotherapy and at risk for developing chemotherapy-induced neutropenia. Since July 2013, lipegfilgrastim...
Approved
Investigational
Matched Description: … Neutropenia and febrile neutropenia (FN) are frequent and potentially fatal complications that occur ... life-threatening infection and sepsis. ... is used as an alternate to [DB00019] for prophylactic use in cancer patients receiving chemotherapy and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … LONQUEX SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 6MG/0.6ML …

Hydrocortisone succinate

Approved
Matched Salts name: … Hydrocortisone sodium succinate …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … HYDROCORTISONE SODIUM SUCCINATE ... Hydrocortisone Sodium Succinate Injection ... Hydrocortisone Sodium Succinate for Injection …

Ustekinumab

Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses. It was generated via recombinant human IL-12 immunization of human Ig (hu-Ig) transgenic mice. It is a targeted biologic disease-modifying anti-rheumatic drug (bDMARDs) that...
Approved
Investigational
Matched Description: … and subcutaneous formulations of the drug based on the dosing schedule and condition being treated. ... the interleukin (IL)-12 and IL-23 cytokines. ... IL-23, which are cytokines that are involved in immune and inflammatory responses. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Skin and Mucous Membrane Agents …
Matched Products: … Stelara Solution for Injection in Pre-Filled Syringe 90 mg/1 mL ... Stelara Solution for Injection in Pre-Filled Syringe 45 mg/0.5mL …

Trospium

Trospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that causes the bladder muscles to contract uncontrollably. An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes, loss of control over urination. Trospium is manufactured by Indevus Pharmaceutical Inc. and...
Approved
Matched Description: … [L6208] An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes ... [L6208] Trospium is manufactured by _Indevus Pharmaceutical Inc._ and was granted FDA approval in 2007 …
Matched Salts name: … Trospium chloride …
Matched Categories: … Alimentary Tract and Metabolism ... trospium and analgesics ... Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … Trospium Chloride ... Trospium Chloride ER …

Guanosine-3'-monophosphate-5'-diphosphate

Experimental
Matched Synonyms: … Guanosine 3'-(dihydrogen phosphate) 5'-(trihydrogen diphosphate) …

Curcuma aromatica root oil

Curcuma aromatica root oil is obtained from the roots of Curcuma aromatica, or more commonly called wild tumeric, via steamed distillation. Curcuma aromatica belongs to the family Zingiberaceae. The wild ginger has been used as a cosmetic herbal where its rhizomes exhibit a distinct fragrance and color. The major constituents...
Approved
Matched Name: … Curcuma aromatica root oil …
Matched Description: … , ar-turmerone and 1,8-cineole [A27219]. ... The wild ginger has been used as a cosmetic herbal where its rhizomes exhibit a distinct fragrance and ... Curcuma aromatica root oil is obtained from the roots of *Curcuma aromatica*, or more commonly called …

Chlorothiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Approved
Vet approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Salts name: … Chlorothiazide sodium …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... Sulfur Compounds ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... chlorothiazide and potassium …
Matched Products: … DIURIL Sodium ... Sodium Diuril ... Chlorothiazide Sodium …

alpha-D-mannose 6-phosphate

Experimental
Matched Synonyms: … α-D-mannose 6-phosphate ... alpha-D-Mannopyranose 6-phosphate …
Matched Name: … alpha-D-mannose 6-phosphate …

Terbutaline

Terbutaline was first synthesized in 1966 and described in the literature in the late 1960s and early 1970s. It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.[A230333,L32093,L32098] Terbutaline was granted FDA approval on 25 March 1974.
Approved
Matched Description: … and early 1970s. ... Terbutaline was first synthesized in 1966[A230333] and described in the literature in the late 1960s …
Matched Products: … SULTER 2.5 MG ... SULTER SOLUCION …

Tobramycin

Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Description: … concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and ... [A232294, A232299, L32739] However, tobramycin can also be administered intravenously and topically to ... L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and …
Matched Mixtures name: … Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone …
Matched Products: … Tobramycin in Sodium Chloride …

Thymidine monophosphate

5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
Experimental
Matched Synonyms: … Thymidine 5'-phosphate ... Thymidine-5'-phosphate ... thymidine 5'-(dihydrogen phosphate) …
Matched Description: … A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Daptomycin

Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Description: … with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and ... -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE). ... A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Daptomycin in Sodium Chloride …
Displaying drugs 776 - 800 of 1134 in total