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Displaying drugs 801 - 825 of 8985 in total

Ticagrelor

Ticagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y12 receptor antagonism. Unlike clopidogrel, ticagrelor is not a prodrug. It is marketed by Astra Zeneca as Brilinta in the US and Brilique or Possia in the EU, . Ticagrelor was...
Approved
Matched Synonyms: … (4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol ... (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo …
Matched Iupac: … [4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol ... (1S,2S,3R,5S)-3-(7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo …
Matched Description: … Ticagrelor was granted EMA approval on 3 December 2010. …
Matched Products: … ABRİLOR 60 MG FİLM KAPLI TABLET, 56 ADET ... GOLWAX 60 MG FİLM KAPLI TABLET, 56 ADET ... ABRİLOR 90 MG FİLM KAPLI TABLET, 56 ADET …

Warfarin

Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. Warfarin has several properties that should be noted when used medicinally,...
Approved
Matched Synonyms: … 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin …
Matched Iupac: … 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one …
Matched Products: … FARGEM 3 ... เบฟาริน 3 ... มอร์ฟาริน-3 …

Duloxetine

Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Matched Synonyms: … (3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine …
Matched Iupac: … methyl[(3S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl]amine …
Matched Products: … DULOXX 60 MG KAPSUL, 56 ADET ... DULOXAT 30 MG KAPSÜL, 56 ADET ... DULAXAT 60 MG KAPSÜL, 56 ADET …

Lamivudine

A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Approved
Investigational
Matched Synonyms: … 2',3'-Dideoxy-3'-thiacytidine ... 3'-Thia-2',3'-dideoxycytidine ... beta-L-2',3'-Dideoxy-3'-thiacytidine …
Matched Description: … A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon …

Amiodarone

Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone...
Approved
Investigational
Matched Synonyms: … 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran ... 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran ... 2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone …
Matched Iupac: … {2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl}diethylamine …
Matched Products: … AMIODARONA 150 MG/ 3 ML ... CORDARONE INJECTION 150 mg/3 ml ... AMIODARONA CLORHIDRATO 150 MG/3 ML …

Dasabuvir

Dasabuvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Synonyms: … Sodium 3-(3-tert-butyl-4-methoxy-5-{6­ [(methylsulfonyl)amino]naphthalene-2-yl}phenyl)-2,6-dioxo-3,6 ... N-{6-[3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl]naphthalen-2-yl}methanesulfonamide …
Matched Iupac: … N-{6-[3-tert-butyl-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2-methoxyphenyl]naphthalen-2-yl}methanesulfonamide …
Matched Products: … EXVIERA 250 MG FILM KAPLI TABLET,56 TABLET …

Nicotine

Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Synonyms: … 3-(N-methylpyrollidino)pyridine ... (S)-3-(1-methylpyrrolidin-2-yl)pyridine ... 3-(2-(N-methylpyrrolidinyl))pyridine …
Matched Iupac: … 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine …
Matched Salts cas: … 6019-06-3 …
Matched Products: … ETAPA 3 ... Habitrol Step 3 ... NICOTINE Transdermal System Step 3 …

Chlorthalidone

Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule...
Approved
Matched Synonyms: … 1-keto-3-(3'-sulfamyl-4'-chlorophenyl)-3-hydroxyisoindoline ... 1-oxo-3-(3-sulfamyl-4-chlorophenyl)-3-hydroxyisoindoline ... 3-hydroxy-3-(4-chloro-3-sulfamylphenyl)phthalimidine …
Matched Iupac: … 2-chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzene-1-sulfonamide …

Quinestrol

The 3-cyclopentyl ether of ethinyl estradiol.
Approved
Matched Synonyms: … Estradiol-17-beta 3-cyclopentyl ether ... 17-alpha-Ethinylestradiol 3-cyclopentyl ether ... 17alpha-Ethynylestradiol 3-cyclopentyl ether …
Matched Description: … The 3-cyclopentyl ether of ethinyl estradiol. …

Iloperidone

Iloperidone is a benzisoxazole and an atypical antipsychotic agent that was first approved by the FDA on May 6, 2009. It is considered to be a second-generation antipsychotic drug with multiple receptor binding profile, although it shows high affinity towards 5-HT2A and dopamine D2 receptors. Iloperidone is currently used to...
Approved
Matched Synonyms: … 1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1- piperidinyl]propoxy]-3-methoxyphenyl]ethanone ... 4'-(3-(4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidino)propoxy)-3'-methoxyacetophenone …
Matched Iupac: … 1-(4-{3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy}-3-methoxyphenyl)ethan-1-one …

Cinnamaldehyde

Cinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour. It occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum such as camphor and cassia. Sensitivity to cinnamaldehyde may be identified with a clinical patch test.
Approved
Experimental
Matched Synonyms: … (E)-3-Phenylpropenal ... (E)-3-Phenyl-propenal ... (3E)-3-phenylprop-2-enal …
Matched Iupac: … (2E)-3-phenylprop-2-enal …

Ketoprofen

Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Approved
Vet approved
Matched Synonyms: … 3-Benzoylhydratropic acid ... 2-(3-Benzoylphenyl)propionic acid ... 3-Benzoyl-α-methylbenzeneacetic acid …
Matched Iupac: … 2-(3-benzoylphenyl)propanoic acid …

Abiraterone

Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Synonyms: … (3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-ol ... 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol …
Matched Iupac: … (3aS,3bR,7S,9aR,9bS,11aS)-9a,11a-dimethyl-1-(pyridin-3-yl)-3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H, …

Vindesine

Vinblastine derivative with antineoplastic activity against cancer. Major side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (antineoplastic combined chemotherapy protocols).
Approved
Investigational
Matched Synonyms: … 3-carbamoyl-4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine ... 3-(aminocarbonyl)-O4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine …

Zimelidine

Zimelidine has been banned worldwide due to serious, sometimes fatal, cases of central and/or peripheral neuropathy known as Guillain-Barré syndrome and due to a peculiar hypersensitivity reaction involving many organs including skin exanthema, flu-like symptoms, arthralgias, and sometimes eosinophilia. Additionally, zimelidine was charged to cause an increase in suicidal ideation...
Approved
Withdrawn
Matched Synonyms: … (Z)-3-(4'-Bromophenyl)-3-(3''-pyridyl)dimethylallylamine …
Matched Iupac: … [(2Z)-3-(4-bromophenyl)-3-(pyridin-3-yl)prop-2-en-1-yl]dimethylamine …

Nepafenac

Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.
Approved
Investigational
Matched Synonyms: … 2-amino-3-benzoylbenzeneacetamide …
Matched Iupac: … 2-(2-amino-3-benzoylphenyl)acetamide …
Matched Products: … NEVANAC 3 MG/ML GÖZ DAMLASI, SÜSPANSİYON …

Methyl nicotinate

Methyl nicotinate is the methyl ester of DB00627 that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation. For veterinary purposes, methyl nicotinate is used to...
Approved
Matched Synonyms: … 3-(Carbomethoxy)pyridine ... 3-(Methoxycarbonyl)pyridine ... Methyl 3-pyridinecarboxylate …
Matched Iupac: … methyl pyridine-3-carboxylate …

Betazole

A histamine H2 agonist used clinically to test gastric secretory function.
Approved
Matched Synonyms: … 1H-pyrazole-3-ethanamine ... 3-(2-aminoethyl)pyrazole ... 2-(3-pyrazolyl)ethylamine …

Montelukast

Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Synonyms: … (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl ... 1-[[[(1 R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl] …
Matched Iupac: … 2-[1-({[(1R)-1-{3-[(1E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl …
Matched Products: … AIRMOL 10 MG FILM TABLET, 56 ADET ... AIRFIX 4 MG CIGNEME TABLETI, 56 ADET ... AIRFIX 5 MG CIGNEME TABLETI, 56 ADET …

Eliglustat

Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher disease.[A3752,L41404] Gaucher disease is a rare genetic disorder characterized by the deficiency of acid β-glucosidase, an enzyme that converts glucosylceramide into glucose and ceramide. In patients with Gaucher disease, the accumulation of glucosylceramide leads to...
Approved
Investigational
Matched Synonyms: … N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)-2-propanyl]octanamide …
Matched Iupac: … N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl]octanamide …
Matched Products: … CERDELGA 84 MG SERT KAPSÜL, 56 ADET …

Zonisamide

Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.[L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel currents or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of...
Approved
Investigational
Matched Synonyms: … 1,2-Benzisoxazole-3-methanesulfonamide ... 3-(Sulfamoylmethyl)-1,2-benzisoxazole ... Benzo[d]isoxazol-3-yl-methanesulfonamide …
Matched Iupac: … (1,2-benzoxazol-3-yl)methanesulfonamide …

Polydatin

Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets...
Approved
Matched Synonyms: … trans-resveratrol 3-β-glucoside ... resveratrol-3-O-b-mono-D-glucoside ... trans-resveratrol 3-β-D-glucoside …
Matched Iupac: … (2S,3R,4S,5S,6R)-2-{3-hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenoxy}-6-(hydroxymethyl)oxane-3,4,5 …

Prochlorperazine

Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.[label] It mainly works by depressing the chemoreceptor trigger zone and blocking...
Approved
Vet approved
Matched Synonyms: … 3-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine ... Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine ... 3-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine …
Matched Iupac: … 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine …
Matched Categories: … Heterocyclic Compounds, 3-Ring …

Edrophonium

A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Approved
Matched Synonyms: … (3-hydroxyphenyl)dimethylethylammonium ... 3-hydroxy-N,N-dimethyl-N-ethylanilinium ... N-ethyl-3-hydroxy-N,N-dimethylanilinium …
Matched Iupac: … N-ethyl-3-hydroxy-N,N-dimethylanilinium …

Cabergoline

Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.
Approved
Matched Synonyms: … 1-((6-allylergolin-8β-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea ... 1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'β-carbonyl)urea ... 1-[(6-allylergoline-8β-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea …
Matched Iupac: … 1-[3-(dimethylamino)propyl]-3-ethyl-1-[(2R,4R,7R)-6-(prop-2-en-1-yl)-6,11-diazatetracyclo[7.6.1.0^{2,7 …
Displaying drugs 801 - 825 of 8985 in total