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Displaying drugs 801 - 825 of 3303 in total
Experimental
Matched Synonyms: … beta-D-Glucose 6-phosphic acid ... β-D-glucose 6-phosphate ... beta-D-glucose-6-phosphate
Matched Name: … beta-D-glucose 6-phosphate
Matched Iupac: … {[(2R,3S,4S,5R,6R)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid
Choline magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug. Trisalicylate significantly reduces methotrexate renal clearance, displacing methotrexate from protein, increasing the fraction unbound by 28% [A19653, A19654].
Approved
Matched Name: … Choline magnesium trisalicylate …
Matched Iupac: … magnesium(2+) (2-hydroxyethyl)trimethylazanium tris(2-hydroxybenzoate) …
Matched Description: … Choline magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Trichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with acetic acid in the presence of a suitable catalyst. In clinical chemistry and biochemistry, it is used as a precipitant of macromolecules including proteins, DNA and RNA. Trichloroacetate is also found in cosmetic treatments and...
Approved
Matched Description: … Trichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with ... , DNA and RNA. ... In clinical chemistry and biochemistry, it is used as a precipitant of macromolecules including proteins …
Matched Salts name: … Trichloroacetic acid
Matched Categories: … Acetates ... Acids, Acyclic ... Carboxylic Acids ... Trichloroacetic Acid
Matched Products: … Trichloroacetic Acid 30% ... Trichloroacetic Acid 15% ... Trichloroacetic Acid 5% …
Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile, prodrug ,fenofibrate, and other conjugated compounds...
Approved
Matched Name: … Fenofibric acid
Matched Iupac: … 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid
Matched Description: … [A32038,L12855] Due to its high hydrophilicity and poor absorption profile,[A32038] prodrug ,[fenofibrate ... ], and other conjugated compounds of fenofibric acid, such as choline fenofibrate, have been developed ... , and mixed dyslipidemia. …
Matched Categories: … Acids, Acyclic ... Fibric Acids ... Carboxylic Acids
Matched Products: … Fenofibric Acid ... Fenofibric acid ... ACIDO FENOFIBRICO 135 MG …
Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.
Approved
Investigational
Matched Synonyms: … 1-butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin ... 1-butyric acid-2-(3-(p-methoxyphenyl)-L-alanine)oxytocin …
Matched Description: … It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Oxytocin and Analogues ... Pituitary and Hypothalamic Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Insulins …
Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to a technetium-99m ion. Following intravenous injection, single photon emission computer tomography (SPECT) imaging of the liver or gallbladder is performed using a gamma camera to detect the gamma rays emitted by the technetium-99m as it...
Approved
Matched Synonyms: … Bis(2-[[2-(3-bromo-2,4,6-trimethylanilino)-2-oxoethyl]-(carboxymethyl)amino]acetate) technetium ... Technetium Tc 99m diisopropyl-iminodiacetic acid
Matched Iupac: … 2-({[(3-bromo-2,4,6-trimethylphenyl)carbamoyl]methyl}(carboxymethyl)amino)acetic acid technetium …
Matched Description: … uptake and fast biliary excretion, resulting in improved hepatic imaging. ... Liver and gallbladder imaging is enabled through attachment to mebrofenin as this molecule has high hepatic ... More specifically, mebrofenin is taken up into hepatocytes through the action of OATP1B1 and OATP1B3 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Indicators and Reagents ... Hepatic and Reticulo Endothelial System ... Amino Acids
ENB-003 is a selective and potent inhibitor of the endothelin B receptor (ETBR) being investigated for cancer.
Investigational
Matched Synonyms: … sodium bispiperidine-carboxamido-dimethylpenatnamido-methoxycarbonyl-indol-propanamidohexanoate …
Matched Description: … ENB-003 is a selective and potent inhibitor of the endothelin B receptor (ETBR) being investigated for …
Efruxifermin is under investigation in clinical trial NCT06215716 (A Study Evaluating Efruxifermin in Subjects With Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and Fibrosis).
Investigational
Matched Synonyms: … ,171-glycine,180-glutamic acid) (human), dimer ... ,171-glycine,180-glutamic acid) (human mutant clone amg876) ... g (synthetic human constant domain fc fragment) fusion protein with fibroblast growth factor 21 (98-arginine
Matched Description: … Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
beta-Alanine is an amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported.
Experimental
Matched Synonyms: … β-alanine ... beta-Alanine ... 3-aminopropanoic acid
Matched Name: … beta-Alanine
Matched Iupac: … 3-aminopropanoic acid
Matched Description: … beta-Alanine is an amino acid formed in vivo by the degradation of [dihydrouracil] and [carnosine]. ... Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound ... may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alanine ... Amino Acids
Investigational
Matched Synonyms: … Arginine glutamate ... L-Arginine L-glutamate ... 2-aminoglutaric acid
Matched Name: … Arginine glutamate …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; (2S)-2-aminopentanedioic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... arginine glutamate ... Alimentary Tract and Metabolism ... Bile and Liver Therapy …
A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA...
Approved
Investigational
Vet approved
Matched Synonyms: … 5-ethyl-5-(sec-pentyl)barbituric acid ... 5-ethyl-5-(1-methylbutyl)barbituric acid
Matched Description: … agent and is usually given orally. ... A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) …
Matched Salts name: … Pentobarbital Sodium
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Nembutal Sodium ... Pentobarbital Sodium ... Nembutal Sodium Cap 100mg …
Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.[A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety.[A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. Its short duration of action...
Approved
Illicit
Matched Synonyms: … 5-sec-butyl-5-ethylbarbituric acid ... 5-ethyl-5-(1-methylpropyl)barbituric acid
Matched Description: … [A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Salts name: … Butabarbital sodium
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Butisol Sodium ... Butisol Sodium Tab 30mg ... Butisol Sodium Tab 15mg …
A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
Approved
Illicit
Matched Synonyms: … 5-ethyl-5-isoamylbarbituric acid ... 5-ethyl-5-isopentylbarbituric acid ... 5-ethyl-5-(3-methylbutyl)barbituric acid
Matched Description: … A barbiturate with hypnotic and sedative properties (but not antianxiety). ... Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with …
Matched Salts name: … Amobarbital sodium
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Amytal Sodium ... Amytal Sodium 500mg ... Amytal Sodium Cap 60mg …
Experimental
Matched Synonyms: … O-sulfo-L-serine ... Serine O-sulfate ... O-sulfonato-L-serine
Matched Name: … L-serine O-sulfate …
Matched Iupac: … (2S)-2-amino-3-(sulfooxy)propanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral …
Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was...
Approved
Matched Synonyms: … Carglumic acid ... Acide carglumique ... Acidum carglumicum …
Matched Name: … Carglumic acid
Matched Iupac: … (2S)-2-(carbamoylamino)pentanedioic acid
Matched Description: … Carglumic acid was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010. ... cause neurologic problems, cerebral edema, coma, and death. ... disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and
Matched Categories: … Amino Acids and Derivatives ... Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Carbamoyl Phosphate Synthetase 1 Activator ... Carbamoyl Phosphate Synthetase 1 Activators …
Matched Products: … Carglumic Acid ... Carglumic acid ... ACIDO CARGLUMICO WAYMADE …
Approved
Matched Iupac: … 3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethoxy}-4-oxobutanoic acid
Matched Salts name: … Hydrocortisone sodium succinate …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … HYDROCORTISONE SODIUM SUCCINATE ... Hydrocortisone Sodium Succinate Injection ... Hydrocortisone Sodium Succinate for Injection …
Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through A protease cleavable valine-alanine
Matched Description: … Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... and improve survival. ... [A234439] Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Approved
Matched Synonyms: … Mefenamic acid ... Acide méfénamique ... Acidum mefenamicum …
Matched Name: … Mefenamic acid
Matched Iupac: … 2-[(2,3-dimethylphenyl)amino]benzoic acid
Matched Description: … A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids ... mefenamic acid
Matched Products: … Mefenamic-Acid ... Mefenamic acid ... Mefenamic Acid
Experimental
Matched Synonyms: … phosphoric acid mono-[2-amino-3-(3H-imidazol-4-yl)-propyl]ester …
Matched Name: … L-histidinol phosphate
Matched Iupac: … [(2S)-2-amino-3-(1H-imidazol-4-yl)propoxy]phosphonic acid
Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.
Approved
Investigational
Nutraceutical
Withdrawn
Matched Synonyms: … 5'-Adenylic acid ... Adenylic acid ... Adenosine-5'-monophosphoric acid
Matched Name: … Adenosine phosphate
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
Matched Description: … intended uses as a vasodilator and an anti-inflammatory. ... Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified ... Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Name: … (2-BROMOETHYL)(2-'FORMYL-4'-AMINOPHENYL) ACETATE
Matched Iupac: … 2-bromoethyl 2-(4-amino-2-formylphenyl)acetate
A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved
Matched Synonyms: … 6-(3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid ... methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Iupac: … chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Salts name: … Cloxacillin sodium ... Cloxacillin sodium hydrate …
Matched Products: … CLOXACILLINA SODICA ... Cloxacillin Sodium for Injection ... Cloxacillin Sodium Sterile Inj 250mg/vial …
Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1 (236-alanine,237-alanine,de-c-terminal-lysine), anti-(human receptor tigit)(human-mus …
Matched Description: … Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination …
Experimental
Matched Synonyms: … Methionine Sulfoxide …
Matched Name: … L-methionine (R)-S-oxide …
Matched Iupac: … (2S)-2-amino-4-[(R)-methanesulfinyl]butanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Approved
Vet approved
Matched Synonyms: … Ampicillin acid ... D-(−)-6-(α-aminophenylacetamido)penicillanic acid
Matched Iupac: … -[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Mixtures name: … Ampicillin Sodium and Sulbactam Sodium ... Ampicillin Sodium and Sulbactam Sodium ... Ampicillin Sodium and Sulbactam Sodium
Matched Salts name: … Ampicillin sodium
Matched Products: … Ampicillin Sodium ... AMPICILLIN SODIUM ... AMPICILLINA SODICA
Displaying drugs 801 - 825 of 3303 in total