Displaying drugs 826 - 850 of 1057 in total
Plamotamab
Plamotamab is under investigation in clinical trial NCT05328102 (Phase 2 Study of Plamotamab Combined With Tafasitamab Plus Lenalidomide Versus Tafasitamab Plus Lenalidomide in Relapsed or Refractory (R/R) Diffuse Large-cell B-cell Lymphoma (DLBCL)).
Investigational
Matched Synonyms: … Anti-cd20/cd3 monoclonal antibody xmab13676 …
EMB-01
EMB-01 is under investigation in clinical trial NCT03797391 (A Dose Escalation Study of EMB-01 in Participants With Advanced/metastatic Solid Tumors).
Investigational
Matched Synonyms: … Anti-egfr/c-met bispecific antibody emb-01 ... Anti-egfr/anti-c-met bispecific antibody emb-01 …
Angelica archangelica root
Angelica archangelica root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Archangelica Officinalis Root Extract …
Diosmetin
Diosmetin is an O-methylated flavone and the aglycone part of the flavonoid glycosides diosmin that occurs naturally in citrus fruits . Pharmacologically, diosmetin is reported to exhibit anticancer, antimicrobial, antioxidant, oestrogenic and anti-inflamatory activities . It also acts as a weak TrkB receptor agonist .
Experimental
Matched Description: … Diosmetin is an O-methylated flavone and the aglycone part of the flavonoid glycosides diosmin that occurs ... Pharmacologically, diosmetin is reported to exhibit anticancer, antimicrobial, antioxidant, oestrogenic and …
Matched Products: … Whoo Gongjinhyang Seol Whitening Jin Essence …
Matched Products: … Whoo Gongjinhyang Seol Whitening Jin Essence …
Axatilimab
Axatilimab is under investigation in clinical trial NCT04301778 (Durvalumab in Combination With a CSF-1R Inhibitor (SNDX-6532) Following Chemo or Radio-embolization for Patients With Intrahepatic Cholangiocarcinoma).
Investigational
Matched Synonyms: … anti-Csf1R monoclonal antibody SNDX-6352 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
XMMME-001-DTPA 111 Indium
Investigational
Matched Synonyms: … Antimelanoma antibody XMMME-001-DTPA 111 Indium …
MDX-210
Investigational
Matched Synonyms: … Bispecific antibody 520c9x22 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ubamatamab
Ubamatamab is under investigation in clinical trial NCT03564340 (Study of REGN4018 Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers).
Investigational
Matched Synonyms: … Anti-muc16/cd3 bite antibody regn4018 ... Bispecific t-cell engager antibody regn4018 …
Volociximab
Investigational
Matched Synonyms: … Anti-alpha5beta1 integrin monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Bemarituzumab
Bemarituzumab is under investigation in clinical trial NCT03694522 (A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 (Mfolfox6) in Gastric/gastroesophageal Junction Cancer (FIGHT)).
Investigational
Matched Synonyms: … Anti-fgfr2 monoclonal antibody fpa144 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
ATG-101
ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, while delivering enhanced anti-tumor activity, with an improved safety profile.
Investigational
Matched Synonyms: … PD-L1/4-1BB bispecific antibody …
Matched Description: … PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, ... ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive …
Matched Description: … PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, ... ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive …
Tidutamab
Tidutamab is under investigation in clinical trial NCT04590781 (Safety and Efficacy of Xmab18087 ± Pembrolizumab in Advanced Merkel Cell Carcinoma or Extensive-stage Small Cell Lung Cancer).
Investigational
Matched Synonyms: … Anti-sstr2/cd3 monoclonal antibody xmab18087 …
Matched Description: … Tidutamab is under investigation in clinical trial NCT04590781 (Safety and Efficacy of Xmab18087 ± Pembrolizumab …
Matched Description: … Tidutamab is under investigation in clinical trial NCT04590781 (Safety and Efficacy of Xmab18087 ± Pembrolizumab …
Nitrofurantoin
Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts...
Approved
Vet approved
Matched Description: … to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and …
Matched Products: … Novo-furan Sus 25mg/5ml …
Matched Products: … Novo-furan Sus 25mg/5ml …
Terbinafine
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Products: … Creobic Gold Cream 1% w/w ... Natural Pet Skin & Coat Antifungal Gel ... Natural Pet Skin & Coat Antifungal Lotion …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Products: … Creobic Gold Cream 1% w/w ... Natural Pet Skin & Coat Antifungal Gel ... Natural Pet Skin & Coat Antifungal Lotion …
Retifanlimab
Retifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor-1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed death-ligand 2 (PD-L2). By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune response against cancer cells. Other monoclonal...
Approved
Investigational
Matched Synonyms: … Anti-PD-1 monoclonal antibody MGA012 …
Matched Description: … -1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed ... By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune ... [L45603] Other monoclonal antibodies that block PD-1 include [pembrolizumab], [nivolumab] and [cemiplimab …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Programmed Death Receptor-1 Blocking Antibody …
Matched Description: … -1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed ... By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune ... [L45603] Other monoclonal antibodies that block PD-1 include [pembrolizumab], [nivolumab] and [cemiplimab …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Programmed Death Receptor-1 Blocking Antibody …
Urea
A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Approved
Investigational
Matched Description: … It is the principal end product of protein catabolism and constitutes about one half of the total urinary …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Emollients and Protectives …
Matched Products: … ERHA21 SOFTENS DRY & ROUGH SKIN 20 ... ERHA21 SOFTENS DRY & ROUGH SKIN 10 …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Emollients and Protectives …
Matched Products: … ERHA21 SOFTENS DRY & ROUGH SKIN 20 ... ERHA21 SOFTENS DRY & ROUGH SKIN 10 …
Edrophonium
A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Approved
Matched Synonyms: … Edrophonium cation …
Matched Description: … A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis ... It has also been used as an antidote to curare principles. …
Matched Description: … A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis ... It has also been used as an antidote to curare principles. …
HPA-23
HPA-23 is an investigational antiviral compound.
Investigational
Matched Synonyms: … Ammonium antimony sodium tungsten oxide ((nh4)17sb9na2w21o86) …
Glucosamine
Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as...
Approved
Investigational
Matched Description: … changes, and synovial membrane inflammation. ... Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone ... for arthritic joint pain, although its acceptance as a medical therapy varies due to contradictory and …
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... Blackmores Joint Formula with Glucosamine and Chondroitin ... Gold Life® Joinflex Capsule …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … GOLD LIFE® JOINTRIL CAPSULE ... Gold Life® Jointril 500 Capsule …
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... Blackmores Joint Formula with Glucosamine and Chondroitin ... Gold Life® Joinflex Capsule …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … GOLD LIFE® JOINTRIL CAPSULE ... Gold Life® Jointril 500 Capsule …
Prednisolone
Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Description: … glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and …
Matched Categories: … Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antineoplastic and Immunomodulating Agents ... Prednisolone and Prodrugs ... Sex Hormones and Insulins …
Matched Products: … PREDNI 10MG LICHT N KR SUS ... PREDNI 25MG LICHT N KR SUS …
Matched Categories: … Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antineoplastic and Immunomodulating Agents ... Prednisolone and Prodrugs ... Sex Hormones and Insulins …
Matched Products: … PREDNI 10MG LICHT N KR SUS ... PREDNI 25MG LICHT N KR SUS …
Girentuximab
Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, an antigen expressed in 95% of clear cell renal cell carcinomas (RCC).
Investigational
Matched Synonyms: … Chimeric (human-murine) G250 IgG monoclonal antibody …
Matched Description: … Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, …
Matched Categories: … Amino Acids, Peptides, and Proteins …
LJP-538
Investigational
Matched Synonyms: … Human IgG1 anti-human cytomegalovirus monoclonal antibody LJP538 …
Rocatinlimab
Rocatinlimab is a subcutaneously administered anti-OX40 antibody developed for the treatment of moderate-to-severe atopic dermatitis. In clinical trials, it has shown significant efficacy and safety compared to a placebo. The drug works by targeting the OX40 receptor, which plays a role in the immune response associated with atopic dermatitis. Despite...
Investigational
Matched Synonyms: … Anti-CD134 human monoclonal antibody (IgG1, KHK4083 dimer) …
Matched Description: … injection reactions such as fever and chills have been reported. ... In clinical trials, it has shown significant efficacy and safety compared to a placebo. ... results, the long-term safety of rocatinlimab requires further investigation, as serious adverse events and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … injection reactions such as fever and chills have been reported. ... In clinical trials, it has shown significant efficacy and safety compared to a placebo. ... results, the long-term safety of rocatinlimab requires further investigation, as serious adverse events and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Vibecotamab
Vibecotamab is under investigation in clinical trial NCT05285813 (A Phase II Study of Vibecotamab (Xmab14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure).
Investigational
Matched Synonyms: … Anti-cd123 x anti-cd3 bispecific antibody xmab14045 …
Matched Description: … investigation in clinical trial NCT05285813 (A Phase II Study of Vibecotamab (Xmab14045) for MRD- Positive AML and …
Matched Description: … investigation in clinical trial NCT05285813 (A Phase II Study of Vibecotamab (Xmab14045) for MRD- Positive AML and …
Displaying drugs 826 - 850 of 1057 in total