Displaying drugs 826 - 850 of 15418 in total
Flupentixol
Flupentixol is an antipsychotic drug of the thioxanthene group. It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. Flupentixol decanoate is one of the active ingredients found in injectable drug formulations: it is produced by esterification of cis(Z)‐flupentixol with decanoic acid. Flupentixol is an antagonist of...
Approved
Investigational
Withdrawn
Matched Iupac: … 2-(4-{3-[(9Z)-2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethan-1-ol …
Matched Description: … by esterification of cis(Z)‐flupentixol with decanoic acid. ... It is approved for use in Canada and other countries around the world, but not in the US. ... It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. …
Matched Salts cas: … 30909-51-4 …
Matched Description: … by esterification of cis(Z)‐flupentixol with decanoic acid. ... It is approved for use in Canada and other countries around the world, but not in the US. ... It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. …
Matched Salts cas: … 30909-51-4 …
Sotagliflozin
Sotagliflozin is a dual inhibitor of SGLT1 and SGLT2, the first of its kind, which is approved for use in the EU, in combination with insulin, to improve glycemic control in patients with type 1 diabetes mellitus (T1DM) and a BMI ≥27 kg/m2. Its potency in inhibiting SGLT2 is similar...
Approved
Investigational
Matched Iupac: … (2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(methylsulfanyl)oxane-3,4,5-triol …
Matched Description: … [L39734] A similar approval has also been sought in the US, but the FDA has since published a proposal ... [L46616] In May 2023, sotagliflozin was approved by the FDA to reduce the risk of cardiovascular death ... diabetes mellitus (T1DM) and a BMI ≥27 kg/m2. …
Matched Categories: … Drugs Used in Diabetes …
Matched Description: … [L39734] A similar approval has also been sought in the US, but the FDA has since published a proposal ... [L46616] In May 2023, sotagliflozin was approved by the FDA to reduce the risk of cardiovascular death ... diabetes mellitus (T1DM) and a BMI ≥27 kg/m2. …
Matched Categories: … Drugs Used in Diabetes …
Ergotamine
A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.
Approved
Matched Iupac: … -4-carboxamide ... (4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6}] ... dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene …
Matched Description: … A vasoconstrictor found in ergot of Central Europe. ... It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … A vasoconstrictor found in ergot of Central Europe. ... It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Carbon monoxide
Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that has a slightly lower density than air. It is toxic to hemoglobin utilizing animals (including humans), when encountered in concentrations above about 35 ppm, although it is also formed in normal animal metabolism in low quantities, and is thought...
Approved
Investigational
Matched Description: … The European Union has banned the use of carbon monoxide as a color stabilizer in meat and fish. ... The FDA classifies this drug as permitted as a food additive in the packaging and preparation of food ... Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that has a slightly lower density than …
Wormwood
Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. …
Japanese Encephalitis Vaccine, Inactivated, Adsorbed
Approved
Investigational
Hemoglobin
The respiratory protein of the red blood cells. It consists primarily of globin and heme.
Approved
Experimental
Investigational
Griseofulvin
An antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.
Approved
Investigational
Vet approved
Matched Description: … Griseofulvin may be given by mouth in the treatment of tinea infections. …
Altretamine
An alkylating agent proposed as an antineoplastic. It also acts as a chemosterilant for male houseflies and other insects.
Approved
Matched Description: … It also acts as a chemosterilant for male houseflies and other insects. …
Sunitinib
Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. On January 26, 2006, the agent was formally approved by the US FDA for the indications of treating renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). For these purposes, sunitinib is generally available as an orally administered formulation....
Approved
Investigational
Matched Description: … Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. ... In addition, sunitinib inhibits other RTKs including RET, CSF-1R, and flt3. ... Sunitinib inhibits cellular signaling by targeting multiple RTKs. …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …
Methenamine
Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
Approved
Vet approved
Matched Description: … Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. ... In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate …
Matched Mixtures name: … All-In-One UTI Emergency Kit …
Matched Mixtures name: … All-In-One UTI Emergency Kit …
Phenylpropanolamine
Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor. It has been used as a decongestant and appetite suppressant. Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes.
Approved
Vet approved
Withdrawn
Matched Description: … Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic ... Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist ... It has been used as a decongestant and appetite suppressant. …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Oteracil
Oteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with DB09257 and DB09256 within the commercially available product "Teysuno". The main active ingredient in Teysuno is DB09256,...
Approved
Matched Description: … The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic ... Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, …
Fluticasone
Fluticasone is a synthetic glucocorticoid available as 2 esters, DB08906 and DB00588[F4355,F4358,F4361,F4364][FDA Label]. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications[F4355,F4358,F4361,F4364][FDA Label]. DB00588 was first approved in 1990 and DB08906 was approved in 2007 .
Approved
Experimental
Matched Iupac: … carbonyl}-1,10-dihydroxy-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … [DB00588] was first approved in 1990[L5962] and [DB08906] was approved in 2007[L5965]. ... Fluticasone is a synthetic glucocorticoid available as 2 esters, [DB08906] and [DB00588][F4355,F4358, …
Matched Description: … [DB00588] was first approved in 1990[L5962] and [DB08906] was approved in 2007[L5965]. ... Fluticasone is a synthetic glucocorticoid available as 2 esters, [DB08906] and [DB00588][F4355,F4358, …
Calcium glubionate anhydrous
Calcium glubionate (or glubionate calcium) is a mineral supplement to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets.
Approved
Matched Iupac: … {[(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl …
Matched Description: … levels in people who do not get enough calcium from their diets. ... Calcium glubionate (or glubionate calcium) is a mineral supplement to prevent or treat low blood calcium …
Matched Description: … levels in people who do not get enough calcium from their diets. ... Calcium glubionate (or glubionate calcium) is a mineral supplement to prevent or treat low blood calcium …
Betamethasone phosphate
Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible betamethasone to agonize glucocorticoid receptors. Betamethasone provides greater anti-inflammatory activity than prednisolone with less sodium and water retention. Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.
Approved
Vet approved
Matched Iupac: … 9b-fluoro-1,10-dihydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible [betamethasone …
Matched Description: … Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible [betamethasone …
Reslizumab
Reslizumab is a humanized interleukin-5 (IL-5) antagonist monoclonal antibody (IgG4 kappa) that is produced by recombinant DNA technology in murine myeloma non-secreting 0 (NS0) cells. IL-5 is a pro-inflammatory cytokine that is responsible for the growth and differentiation, recruitment, activation, and survival of eosinophils [FDA Label]. Elevated levels of eosinophils...
Approved
Investigational
Matched Description: … In addition, a significant improvement in lung function was seen, as measured by the volume of air exhaled ... by patients in one second [L1133]. ... by recombinant DNA technology in murine myeloma non-secreting 0 (NS0) cells. …
Ulobetasol
Ulobetasol is a highly potent corticosteroid. It is structurally related to clobetasol. Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L15102]
Ulobetasol was granted FDA approval on 17 December 1990.
Approved
Matched Description: … Ulobetasol is a highly potent corticosteroid.[A215597] It is structurally related to [clobetasol]. ... [A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis …
Lucinactant
Lucinactant is a new synthetic peptide-containing surfactant for intratracheal use. It contains sinapultide, a novel, hydrophobic, 21-amino acid peptide (leucine and lysine repeating units, KL4 peptide) designed to mimic human surfactant protein-B (SB-P). More specifically, it mimics the C-terminal amphipathic helical domain of this protein. It also consists of phospholipids...
Approved
Investigational
Matched Description: … Lucinactant is a new synthetic peptide-containing surfactant for intratracheal use. ... It contains sinapultide, a novel, hydrophobic, 21-amino acid peptide (leucine and lysine repeating units ... phospholipids (dipalmitoylphosphatidylcholine, DPPC and palmitoyloleoyl phosphatidylglycerol, POPG) and a …
Penicillium glaucum
Penicillium glaucum allergenic extract is used in allergenic testing.
Approved
Matched Description: … Penicillium glaucum allergenic extract is used in allergenic testing. …
Matched Mixtures name: … Molds - Mold Mix 4 …
Matched Mixtures name: … Molds - Mold Mix 4 …
Methylphenobarbital
A barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
Approved
Matched Description: … A barbiturate that is metabolized to phenobarbital. ... It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital …
D-Methionine
Approved
Experimental
Investigational
Matched Iupac: … (2R)-2-amino-4-(methylsulfanyl)butanoic acid …
Matched Mixtures name: … NUTRINEAL PD]4 Peritoneal Dialysis Solution with 1.1% Amino Acids …
Matched Mixtures name: … NUTRINEAL PD]4 Peritoneal Dialysis Solution with 1.1% Amino Acids …
Carya illinoinensis pollen
Carya illinoinensis pollen allergenic extract is used in allergenic testing.
Approved
Matched Description: … Carya illinoinensis pollen allergenic extract is used in allergenic testing. …
Matched Mixtures name: … Central Eastern 4 Tree Pollen Mix ... Central Eastern 4 Tree Pollen Mix ... Central Eastern 4 Tree Pollen Mix …
Matched Mixtures name: … Central Eastern 4 Tree Pollen Mix ... Central Eastern 4 Tree Pollen Mix ... Central Eastern 4 Tree Pollen Mix …
Sodium phosphate, dibasic, unspecified form
Approved
Experimental
Matched Mixtures name: … Aminosyn II in Dextrose …
Displaying drugs 826 - 850 of 15418 in total