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Displaying drugs 851 - 875 of 1133 in total

Donepezil

In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some...
Approved
Matched Description: … with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. ... derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and ... Donepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … ANDEM 5 MG FILM TABLET, 14 ADET ... ANDEM 5 MG FILM TABLET, 28 ADET ... ANDEM 10 MG FILM TABLET, 14 ADET …

Cefprozil

Cefprozil is a cephalosporin antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others.
Approved
Matched Description: … skin, bronchitis, and others. ... antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and …
Matched Products: … PREFIX 250 MG FILM TABLET, 10 ADET ... PREFIX 250 MG FILM TABLET, 14 ADET ... PREFIX 250 MG FILM TABLET, 20 ADET …

Dapoxetine

Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation. In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo. Alza submitted a NDA to the FDA for dapoxetine for the treatment of premature ejaculation...
Investigational
Matched Mixtures name: … DAPOXIL 30/50 MG FILM KAPLI TABLET,18 FILM KAPLI TABLET ... DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLET ... DAPOKSEL 30 MG/50 MG FILM TABLET ,6 FILM TABLET …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … DAPIGRA 30 MG FILM TABLET ,3 FILM TABLET ... DAPIGRA 30 MG FILM TABLET ,6 FILM TABLET ... DAPIGRA 60 MG FILM TABLET ,3 FILM TABLET …

Dexketoprofen

Dexketoprofen is a non-steroidal anti-inflammatory drug. It is available in the various countries in Europe, Asia and Latin America. It has analgesic, antipyretic and anti-inflammatory properties .
Approved
Investigational
Matched Description: … It is available in the various countries in Europe, Asia and Latin America. ... It has analgesic, antipyretic and anti-inflammatory properties [L1298]. …
Matched Mixtures name: … INDEXPA SR 75/300MG FILM KAPLI TABLET, 10 SR FILM KAPLI TABLET ... INDEXPA SR 75/300MG FILM KAPLI TABLET, 20 SR FILM KAPLI TABLET ... SKUDEXA FILM-COATED TABLET 75 MG/25 MG …
Matched Categories: … Ketoprofen and isomer ... Antiinflammatory and Antirheumatic Products ... tramadol and dexketoprofen ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … SERTOFEN 25 MG FILM TABLET ,FILM TABLET, 10 ADET ... SERTOFEN 25 MG FILM TABLET ,FILM TABLET, 20 ADET ... KETESSE 25MG FILM COATED TABLET …

Vonoprazan

Vonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H+, K+-ATPase-mediated gastric acid secretion. PCABs represent an alternative to proton-pump inhibitors for the treatment of acid-related disorders. Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require acid-resistant formulations. Furthermore, vonoprazan is 350-times more potent...
Approved
Investigational
Matched Description: … Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require ... In February 2015, vonoprazan was first marketed in Japan for the treatment of acid-related disorders and ... In May 2022, the FDA approved the use of vonoprazan in a co-packaged product containing amoxicillin and …
Matched Categories: … Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... vonoprazan, amoxicillin and clarithromycin ... vonoprazan, amoxicillin and metronidazole ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Vocinti 20mg Film-Coated Tablet ... Vocinti 10mg Film-Coated Tablet ... VOCINTI FILM-COATED TABLET 20MG …

Erlotinib

Erlotinib is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and several other types of cancer. It is typically marketed under the trade name Tarceva. Erlotinib binds to the epidermal growth factor receptor (EGFR)...
Approved
Investigational
Matched Description: … EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and ... , which is a mutant form of tyrosine kinase JAK2 found in most patients with polycythemia vera (PV) and ... This finding introduces the potential use of erlotinib in the treatment of JAK2V617F-positive PV and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … TARCEVA FILM-COATED TABLET 25 MG ... TARCEVA FILM-COATED TABLET 100 MG ... TARCEVA FILM-COATED TABLET 150 MG …

Zofenopril

Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.
Approved
Matched Description: … Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. …
Matched Mixtures name: … BIFRIL PLUS 30/12.5 MG FILM TABLET, 28 ADET ... BIFRIL PLUS 30/12.5 MG FILM TABLET, 84 ADET ... ZOPROTEC PLUS 30/12.5 MG FILM TABLET, 28 ADET …
Matched Categories: … ACE Inhibitors and Diuretics ... Amino Acids, Peptides, and Proteins ... zofenopril and diuretics ... zofenopril and nebivolol …
Matched Products: … BIFRIL 15 MG (FILM-COATED TABLETS) ... BIFRIL 30 MG (FILM-COATED TABLETS) ... BIFRIL 30 MG FILM TABLET, 14 ADET …

Gefitinib

Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … VEIASU FILM-COATED TABLETS 250 MG ... Iressa 250mg Film-coated Tablet ... GEFTINAT FILM COATED TABLETS 250 MG …

Lornoxicam

Lornoxicam (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug. Lornoxicam is approved for use in Japan.
Approved
Investigational
Matched Description: … new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … XEFO 4 MG FILM KAPLI TABLET, 20 ADET ... XEFO RAPID 8 MG FILM KAPLI TABLET ... XEFO 8 MG FILM KAPLI TABLET, 20 ADET …

Valaciclovir

Valaciclovir (valacyclovir), also known as Valtrex, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline . Valacyclovir is the L-valine ester of aciclovir. It...
Approved
Investigational
Matched Description: … Valaciclovir (valacyclovir), also known as _Valtrex_, is an antiviral drug that has been used to manage and ... It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline [L5671]. ... This class of drugs forms an important part of hepatitis, HIV, and cytomegalovirus drug regimens [A175900 …
Matched Categories: … Acyclovir and prodrug ... Amino Acids, Peptides, and Proteins ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … Mar-valacyclovir ... VIROMED 500 MG FILM TABLET,10 ADET ... VIROMED 500 MG FILM TABLET,42 ADET …

Benidipine

Benidipine has the formula 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine-dicarboxylic acid methyl 1-(phenylmethyl)-3-piperidinyl ester hydrochloride. It is a synthetic dihydropyridine derivative that has anti-hypertensive and anti-anginal actions. It was originated in Japan by Kyowa Hakko, it is submitted for FDA approval and it is currently available in some Asian countries like India and Japan.[L1385, L1386]
Experimental
Matched Description: … available in some Asian countries like India and Japan. ... It is a synthetic dihydropyridine derivative that has anti-hypertensive and anti-anginal actions. ... [A31948] It was originated in Japan by Kyowa Hakko, it is submitted for FDA approval and it is currently …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … BENIPIN 4 MG FILM TABLET,TABLET, 30 ADET ... BENIPIN 8 MG FILM TABLET,TABLET, 30 ADET ... BENİTİDE 4 MG FİLM KAPLI TABLET, 30 ADET …

Olaparib

Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2.[L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell death. Olaparib...
Approved
Matched Description: … Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and ... [L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health ... [L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Lynparza 150 mg Film-Coated Tablets ... Lynparza 100 mg Film-Coated Tablets ... LYNPARZA FILM-COATED TABLET 150MG …

Empagliflozin

Empagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily responsible for the reabsorption of glucose in the kidney. It is used clinically as an adjunct to diet and exercise, often in combination with other drug therapies,[L13673,L13679,L11479] for the management of type 2 diabetes mellitus. The first known inhibitor...
Approved
Matched Description: … Empagliflozin was further approved by the EMA in March 2022 and Health Canada in April 2022, making it ... [L13688] The first known inhibitor of SGLTs, phlorizin, was isolated from the bark of apple trees ... led to the FDA approval of [canagliflozin] in 2013 and both [dapagliflozin] and empagliflozin in 2014 …
Matched Mixtures name: … Glyxambi Film-Coated Tablets 25mg/5mg ... Glyxambi Film-Coated Tablets 10mg/5mg ... GLYXAMBI FILM-COATED TABLETS 25 MG/5 MG …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and empagliflozin ... linagliptin and empagliflozin ... metformin, linagliptin and empagliflozin …
Matched Products: … JARDIANCE FILM-COATED TABLETS 10MG ... JARDIANCE FILM-COATED TABLET 25MG ... Jardiance 10mg film coated tablets …

Prucalopride

Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties. The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. Prucalopride was developed by Shire Development LLC...
Approved
Matched Description: … dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and ... A40250] in Canada on December 7, 2011 and by the FDA on December 17, 2018. ... [A40254] Prucalopride was developed by Shire Development LLC and approved for use in Europe in 2009,[ …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … RESOLOR 1mg Film Coated Tablets ... RESOLOR 2mg Film Coated Tablets ... Resolor Film-coated Tablet 2 mg …

Risedronic acid

Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Description: … acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and …
Matched Mixtures name: … FEMARİS PLUS 150 MG/5600 IU FİLM KAPLI TABLET, 3 ADET …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Drugs Affecting Bone Structure and Mineralization ... risedronic acid and colecalciferol ... risedronic acid and calcium, sequential ... risedronic acid, calcium and colecalciferol, sequential …
Matched Products: … ACTEDAY 5 MG FİLM TABLET, 28 ADET ... BONEPLUS 5 MG FİLM TABLET, 28 ADET ... INDRONATE FILM-COATED TABLET 35 MG …

Ebastine

Ebastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.
Approved
Investigational
Matched Products: … Kestine 10mg film-coated tablets ... Kestine 20mg film-coated tablets ... KESTINE FILM-COATED TABLET 20MG …

(2S)-2-Ammonio-3-[5-(2-methyl-2-propanyl)-3-oxido-1,2-oxazol-4-yl]propanoate

Experimental
Matched Name: … (2S)-2-Ammonio-3-[5-(2-methyl-2-propanyl)-3-oxido-1,2-oxazol-4-yl]propanoate …

Bacampicillin

Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of...
Approved
Investigational
Matched Description: … Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. ... It is used to cure infection of upper and lower respiratory tract; skin and soft tissue; urinary tract ... and acute uncomplicated gonococcal urethritis etc. …
Matched Products: … İEBAK 400 MG FILM TABLET 10 ADET ... İEBAK 800 MG FILM TABLET 10 ADET ... SANOSİLİN 400 MG FİLM TABLET, 10 TABLET …

Roflumilast

Roflumilast is a highly selective phosphodiesterase-4 (PDE4) inhibitor. PDE4 is a major cyclic-3',5′-adenosinemonophosphate (cyclic AMP, cAMP)-metabolizing enzyme expressed on nearly all immune and pro-inflammatory cells, in addition to structural cells like those of the smooth muscle or epithelium. The resultant increase in intracellular cAMP induced by roflumilast's inhibition of PDE4...
Approved
Matched Description: … adenosinemonophosphate (cyclic AMP, cAMP)-metabolizing enzyme [L37564] expressed on nearly all immune and ... [L46546] It was first approved by the EMA in July 2010, and by the FDA in January 2018. ... The cream formulation was first approved by the FDA in July 2022 [L42580] and by Health Canada in April …
Matched Products: … DAXAS 500 MCG FILM-COATED TABLETS ... DAXAS 500 MCG FILM TABLET, 30 ADET ... DAXAS 500 MCG FILM TABLET, 90 ADET …

Ribavirin

Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. HCV is a single-stranded RNA virus that is categorized...
Approved
Matched Description: … Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine ... The dual therapy was administered for 48 weeks in patients with genotype 1, 4, 5, and 6, and 24 weeks ... nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Copegus film coated tablet 200mg ... VIRON 400 MG FİLM KAPLI TABLET, 56 ADET ... VİRANİS 200 MG FİLM TABLET, 70 ADET …

Rosuvastatin

Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Description: … belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and ... of metabolic reactions involved in the production of several compounds involved in lipid metabolism and ... including cholesterol, low-density lipoprotein (LDL) (sometimes referred to as "bad cholesterol"), and …
Matched Mixtures name: … Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... rosuvastatin and valsartan ... gemigliptin and rosuvastatin ... rosuvastatin and ramipril …
Matched Products: … Mar-rosuvastatin ... RONAP 20 MG FILM TABLET , FILM TABLET, 28 ADET ... RONAP 20 MG FILM TABLET , FILM TABLET, 84 ADET …

Sultamicillin

Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).
Approved
Investigational
Matched Description: … Pneumonia and Chronic Obstructive Pulmonary Disease (COPD). ... Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated …
Matched Products: … AMPISID 750 MG FILM TABLET, 10 ADET ... AMPİSİD 375 MG FİLM TABLET, 10 ADET ... DEVASID 375 MG FILM TABLET, 20 ADET …

Metformin

Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched Description: … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management ... It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and ... [A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval …
Matched Mixtures name: … PREKO 15/850 MG FILM TABLET, 60 ADET ... PREKO 15/850 MG FILM TABLET, 30 ADET ... PREKO 15/850 MG FILM TABLET, 90 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and ertugliflozin ... metformin and gemigliptin ... metformin and sulfonylureas ... metformin and linagliptin …
Matched Products: … Mar-metformin ... METVEL 850 MG FILM KAPLI TABLET, 50 FILM KAPLI TABLET ... METVEL 850 MG FILM KAPLI TABLET, 100 FILM KAPLI TABLET …

Voriconazole

Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha sterol demethylase...
Approved
Matched Description: … These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. ... [L15571] It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised …
Matched Categories: … Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … VFEND FILM-COATED TABLET 50 mg ... VFEND FILM-COATED TABLET 200 mg ... VFEND 50 MG FILM TABLET, 14 ADET …

Montelukast

Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Description: … [A178651] And although these kinds of effects are currently included in the official prescribing information ... for montelukast,[L6301,L6304,L6307,L6310,L6325,L6328,L6331] the drug still sees extensive use worldwide ... via millions of prescriptions annually and has since become available as a generic and as a brand name …
Matched Mixtures name: … LORCLAST 5 MG/10 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 30 ADET ... DESMONT 5/10 MG 90 FILM KAPLI TABLET ... LEPIXOS 5 MG/10 MG FILM TABLET ,30 ADET …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Mar-montelukast ... SINAIR 10 MG FILM KAPLI TABLET ,FILM TABLET, 28 ADET ... OXAIR FILM COATED TABLET 10MG …
Displaying drugs 851 - 875 of 1133 in total