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Displaying drugs 876 - 900 of 2795 in total
Experimental
Matched Synonyms: … acid ... (6R)-5-Acetamido-6-[(1R,2R)-3-amino-1,2-dihydroxypropyl]-2,6-anhydro-3,5-dideoxy-L-threo-hex-2-enonic …
Matched Name: … 9-Amino-2-deoxy-2,3-dehydro-n-acetyl-neuraminic acid
Matched Iupac: … 4S)-2-[(1R,2R)-3-amino-1,2-dihydroxypropyl]-3-acetamido-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
Investigational
Matched Synonyms: … Fumaric acid ... Fumaricum acidum ... (2E)-2-butenedioic acid
Matched Name: … Fumaric acid
Matched Iupac: … (2E)-but-2-enedioic acid
Matched Categories: … Acids, Acyclic ... fumaric acid ... Carboxylic Acids ... Dicarboxylic Acids
Fosmanogepix is under investigation in clinical trial NCT03604705 (An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia).
Investigational
Matched Synonyms: … 2-amino-3-[3-[[4-(2-pyridyloxymethyl)phenyl]methyl]isoxazol-5-yl]pyridin-1-ium-1-yl]methyl hydrogen phosphate
Matched Description: … Fosmanogepix is under investigation in clinical trial NCT03604705 (An Efficacy and Safety Study of APX001 …
Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES …
Matched Description: … of somatrogon and allows its once-weekly dosing. ... adolescence and regulating metabolic function in adulthood. ... by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues ... Somatropin and Somatropin Agonists …
A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Approved
Investigational
Matched Synonyms: … Amifostine anhydrous
Matched Iupac: … ({2-[(3-aminopropyl)amino]ethyl}sulfanyl)phosphonic acid
Matched Description: … It causes splenic vasodilation and may block autonomic ganglia. …
Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus. When it is combined with amoxicillin, clavulanic acid is...
Approved
Vet approved
Matched Synonyms: … Clavulanic acid ... Acide clavulanique ... Acidum clavulanicum …
Matched Name: … Clavulanic acid
Matched Iupac: … (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Description: … [T665] Clavulanic acid is derived from the organism Streptomyces clavuligerus. ... Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin ... [A182228]When it is combined with amoxicillin, clavulanic acid is frequently known as Augmentin, Co-Amoxiclav …
Matched Mixtures name: … Amoxicillin Sodium and Potassium Clavulanate for Injection ... Amoxicillin Sodium and Potassium Clavulanate for Injection ... Amoxicillin Sodium and Potassium Clavulanate for Injection …
Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is structurally similar to other corticosteroids such as hydrocortisone and prednisolone. Dexamethasone acetate has largely been replaced by dexamethasone phosphate and...
Approved
Investigational
Vet approved
Matched Synonyms: … Dexamethasone acetate anhydrous ... Dexamethasone acetate, anhydrous
Matched Description: … [A188724] Dexamethasone acetate has largely been replaced by [dexamethasone] phosphate and continues ... one-third in patients on oxygen therapy and mechanical ventilation, respectively. ... previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and
Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of...
Approved
Matched Iupac: … }.0^{34,39}]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid
Matched Description: … kidneys and the inner ear. ... It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to ... liquid treatment option available for the the treatment of _Clostridium difficile_ associated diarrhea and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism …
Matched Products: … Vancomycin Injection USP In 5% Dextrose ... Vancomycin Injection USP In 0.9% Sodium Chloride …
Experimental
Matched Iupac: … 3,3-dimethyl-7-oxo-6-[(2R)-2-phenyl-2-sulfoacetamido]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Salts name: … Sulbenicillin sodium
Matched Products: … SULBENICILLIN SODIUM
Experimental
Matched Name: … Mercaptomethyl Phosphonate
Matched Iupac: … (sulfanylmethyl)phosphonate
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Synonyms: … 4-amino-10-methylfolic acid ... 4-amino-N(10)-methylpteroylglutamic acid ... N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Matched Iupac: … -[(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid
Matched Description: … Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and ... inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and
Matched Salts name: … Methotrexate sodium
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists ... Nucleic Acid Synthesis Inhibitors …
Matched Products: … Methotrexate Sodium ... Ratio-methotrexate Sodium ... Methotrexate Sodium Inj 20mg …
Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Synonyms: … Etidronic acid ... acide étidronique ... acidum etidronicum …
Matched Name: … Etidronic acid
Matched Iupac: … (1-hydroxy-1-phosphonoethyl)phosphonic acid
Matched Description: … ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and
Matched Categories: … etidronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization ... etidronic acid
Experimental
Matched Name: … Alpha-Ribazole-5'-Phosphate
Matched Iupac: … [(2R,3S,4R,5S)-5-(5,6-dimethyl-1H-1,3-benzodiazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
Experimental
Matched Name: … 2-Amino-Vinyl-Phosphate
Matched Iupac: … {[(1E)-2-aminoethenyl]oxy}phosphonic acid
Experimental
Matched Name: … Indole-3-Propanol Phosphate
Matched Iupac: … [3-(1H-indol-3-yl)propoxy]phosphonic acid
Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
Experimental
Matched Name: … Nicotinamide adenine dinucleotide phosphate
Matched Description: … It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced ... Nicotinamide adenine dinucleotide phosphate. ... the 5'-phosphate adenosine 2',5'-bisphosphate. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Enzymes and Coenzymes …
Experimental
Matched Name: … Indole-3-Glycerol Phosphate
Matched Iupac: … [(2R,3S)-2,3-dihydroxy-3-(1H-indol-3-yl)propoxy]phosphonic acid
Matched Categories: … Indicators and Reagents ... Sugar Phosphates
Experimental
Matched Name: … DIETHYL 4-METHOXYPHENYL PHOSPHATE
Matched Iupac: … diethyl 4-methoxyphenyl phosphate
One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Approved
Investigational
Vet approved
Matched Description: … combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and
Matched Salts name: … Sulfadiazine sodium
Matched Categories: … sulfadiazine and tetroxoprim ... Sulfonamides and trimethoprim ... sulfadiazine and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Sulfadiazine Sodium
Phenylbutyric acid is a fatty acid and a derivative of butyric acid naturally produced by colonic bacteria fermentation. It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone. It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders.[L386,L42105]
Approved
Investigational
Matched Synonyms: … Benzenebutyric acid ... 4-phenylbutyric acid ... 4-Phenyl-n-butyric acid
Matched Name: … Phenylbutyric acid
Matched Iupac: … 4-phenylbutanoic acid
Matched Description: … Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria ... It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting ... [A249035] It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders. …
Matched Salts name: … Sodium phenylbutyrate …
Matched Categories: … sodium phenylbutyrate and ursodoxicoltaurine ... Acids, Carbocyclic ... Alimentary Tract and Metabolism ... Carboxylic Acids ... sodium phenylbutyrate …
Matched Products: … Sodium Phenylbutyrate …
Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Mixtures name: … Methylprednisolone Sodium Succinate for Injection, USP ... Methylprednisolone Sodium Succinate for Injection, USP …
Matched Categories: … Sex Hormones and Insulins ... methylprednisolone and antibiotics ... methylprednisolone and antiinfectives ... methylprednisolone and antiinfectives ... Ophthalmological and Otological Preparations …
Matched Products: … METHYLPREDNISOLON ACIS 4MG ... METHYLPREDNISOLON ACIS 8MG ... METILPREDNISOLONA SODIO SUCCINATO. METIL PREDNISOLONA 500 MG. PARA RECONSTITUIR A 4 ML. …
Cupric chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).
Approved
Investigational
Matched Synonyms: … Cupric chloride anhydrous
Matched Salts name: … Cupric chloride dihydrate
Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It...
Approved
Matched Iupac: … (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
Matched Description: … levels and prevent cardiovascular disease. ... HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol ... Fluvastatin is a racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. …
Matched Salts name: … Fluvastatin sodium
Matched Categories: … Fatty Acids ... Heptanoic Acids
Matched Products: … Fluvastatin Sodium ... Fluvastatin Sodium ER …
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Description: … of serotonin reuptake and has little effect on other neurotransmitters. ... [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. ... uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and
Matched Products: … Paroxetine Hydrochloride Anhydrous
Experimental
Matched Name: … N-Bromoacetyl-Aminoethyl Phosphate
Matched Iupac: … [2-(N-bromoacetamido)ethoxy]phosphonic acid
Displaying drugs 876 - 900 of 2795 in total