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Displaying drugs 876 - 900 of 1086 in total
Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Matched Description: … Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine ... BCR-ABL inhibitors like bosutinib inhibit most resistance-conferring BCR-ABL mutations except V299L and ... obtained from the open-label, randomized, multicenter trial BFORE that showed a significant improvement in major
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … BOSULİF 500 MG FİLM KAPLI TABLET, 28 ADET ... BOSULİF 500 MG FİLM KAPLI TABLET, 30 ADET ... BOSULİF 100 MG FİLM KAPLI TABLET, 28 ADET …
Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic...
Approved
Investigational
Matched Description: … It is structurally and functionally related to another GABA derivative, [pregabalin]. ... other anti-epileptics, such as a relatively benign adverse effect profile, wide therapeutic index, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gabapentin and Prodrugs …
Matched Products: … GEMUDA 100 MG FILM TABLET , FILM TABLET, 20 ADET ... GEMUDA 300 MG FILM TABLET , FILM TABLET, 50 ADET ... GEMUDA 400 MG FILM TABLET , FILM TABLET, 50 ADET …
Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine derivative. The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and reduces the chance of resistance...
Approved
Matched Description: … [A31331] Rilpivirine was developed by Tilbotec, Inc. and FDA approved on May 20, 2011. ... [A31329] The internal conformational flexibility of rilpivirine and the plasticity of it interacting ... binding site gives it a very high potency and reduces the chance of resistance compared to other NNRTI's …
Matched Mixtures name: … COMPLERA FILM-COATED TABLET 200MG/25MG/300MG ... ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 90 ADET ... ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 30 ADET …
Matched Categories: … dolutegravir and rilpivirine ... emtricitabine, tenofovir disoproxil and rilpivirine ... emtricitabine, tenofovir alafenamide and rilpivirine …
Matched Products: … EDURANT FILM-COATED TABLET 25 MG ... Edurant 25mg film-coated tablet ... EDURANT 25 MG FILM KAPLI TABLET, 30 ADET …
Lercanidipine is a calcium channel blocker of the dihydropyridine class. It is sold under various commercial names including Zanidip.
Approved
Investigational
Matched Mixtures name: … ZANITEK 10 MG/10MG FILM TABLET,90 ADET ... ZANITEK 10 MG/10MG FILM TABLET, 30 ADET ... ZANITEK 20 MG/10MG FILM TABLET, 30 ADET …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... valsartan and lercanidipine ... enalapril and lercanidipine ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Matched Products: … ZANIDIP 10MG FILM COATED TABLETS ... Zanidip 20mg, film-coated tablet ... LERCADIP 10 MG FILM TABLET, 30 ADET …
Cefditoren is an oral third-generation cephalosporin. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.
Approved
Investigational
Matched Products: … CEFITEN 200 MG FILM TABLET, 10 ADET ... CEFITEN 400 MG FILM TABLET, 14 ADET ... CEFITEN 400 MG FILM TABLET, 20 ADET …
Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. It is reported to exhibit potency that is 50-450 times higher than that of the first generation...
Approved
Investigational
Matched Description: … [L6676] Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. ... [A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzamides and benzamide derivatives …
Matched Products: … Inlyta Film-coated Tablets 1mg ... Inlyta Film-coated Tablets 5mg ... INLYTA 3 MG FİLM KAPLI TABLET, 28 ADET …
Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from Micromonospora purpurea in 1963. It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability.[A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment...
Approved
Vet approved
Matched Description: … Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ ... is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and ... [A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but …
Matched Mixtures name: … Garasone Ophthalmic and Otic Solution ... Diprogenta - Salbe
Matched Categories: … Ophthalmological and Otological Preparations …
Matched Products: … INFECTOGENTA SALBE 0.1% …
Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus. Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.
Approved
Investigational
Matched Mixtures name: … Steglujan (Ertugliflozin 5mg/Sitagliptin 100mg) Film-Coated Tablets ... Steglujan (Ertugliflozin 15mg/Sitagliptin 100mg) Film-Coated Tablets ... Segluromet (Ertugliflozin 2.5mg/ Metformin 500mg) Film-Coated Tablet …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and ertugliflozin ... sitagliptin and ertugliflozin …
Matched Products: … STEGLATRO FILM-COATED TABLETS 5MG ... Steglatro 5mg Film-Coated Tablets ... STEGLATRO FILM-COATED TABLETS 15MG …
Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of interaction with sodium channels. Lacosamide was first approved by the European Commission in August 2008 and was later...
Approved
Matched Description: … [A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved …
Matched Products: … VIMPAT 50 MG (FILM-COATED TABLETS) ... VIMPAT 100 MG (FILM-COATED TABLETS) ... BENVIDA 50 MG FILM KAPLI TABLET, 14 ADET …
Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in...
Approved
Matched Description: … It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies ... [A32299] Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in November 2013 ... [L45894] Ibrutinib was approved by the EMA in October 2014 [L45884] and by Health Canada in November …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … IMBRUVICA FILM-COATED TABLETS 140MG ... IMBRUVICA FILM-COATED TABLETS 560MG ... IMBRUVICA FILM-COATED TABLETS 420MG …
Ornidazole has been used in trials studying the prevention of Elective Colorectal Surgery.
Investigational
Matched Mixtures name: … ORNISASIN 500 MG/500 MG FILM TABLET, 10 ADET ... ORNISASIN 500 MG/500 MG FILM TABLET, 20 ADET ... ORCIPOL 500 MG/500 MG FILM TABLET, 10 ADET …
Matched Categories: … ofloxacin and ornidazole ... cefixime and ornidazole ... Genito Urinary System and Sex Hormones ... levofloxacin and ornidazole ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … BITAZOL 250 MG FILM TABLET, 20 ADET ... ORNITOP 250 MG FILM TABLET, 20 ADET ... ORNITOP 500 MG FILM TABLET, 10 ADET …
Experimental
Matched Name: … 5-Pyrimidinyl)Methyl]-4-Methyl-5-(4,6,6-Trihydroxy-3,5-Dioxa-4,6-Diphosphahex-1-Yl)Thiazolium Inner Salt
Canagliflozin, also known as Invokana, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise [FDA label]. It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018...
Approved
Matched Description: … inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and ... It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018 …
Matched Mixtures name: … FILM-COATED TABLETS 50 MG / 1000 MG ... FILM-COATED TABLETS 50 MG / 500 MG ... FILM-COATED TABLETS 150 MG / 500 MG …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and canagliflozin …
Matched Products: … FILM-COATED TABLETS 100 MG ... FILM-COATED TABLETS 300 MG ... Invokana 300mg Film-Coated Tablets …
Lorlatinib is a third-generation ALK tyrosine kinase inhibitor (TKI) for patients with ALK-positive metastatic non-small cell lung cancer which was first approved by the US FDA in November of 2018. It was subsequently approved by the EMA in 2019 for the treatment of select patients with previously treated advanced ALK-positive...
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Lorviqua 100 mg Film-Coated Tablets ... LORVIQUA FILM-COATED TABLET 25MG ... LORVIQUA FILM-COATED TABLET 100MG …
Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to prevent organ rejection after hepatic, renal, and cardiac transplants. It is...
Approved
Investigational
Matched Description: … Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified ... to prevent organ rejection after hepatic, renal, and cardiac transplants. ... [A180805] This drug is an immunosuppressant combined with drugs such as [Cyclosporine] and corticosteroids …
Matched Categories: … Mycophenolic Acid and Prodrugs …
Matched Products: … MYFENAX FILM-COATED TABLETS 500MG ... TARBETAX 500 MG FILM TABLET, 150 ADET ... CELLCEPT (FILM-COATED TABLETS 500 MG) …
Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.[A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949 and is now commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive options such as surgery or radioactive iodine therapy are inappropriate.[L8336,L8339]...
Approved
Matched Description: … [A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949[A184502] and is now ... [carbimazole], which is an antithyroid medication used in the United Kingdom and parts of the former ... thionamide used in North America, [propylthiouracil],[L8339] and is the active metabolite of the pro-drug …
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … PERİZOL 20 MG FİLM TABLET, 100 ADET ... PERİZOL 20 MG FİLM TABLET, 30 ADET ... PERİZOL 20 MG FİLM TABLET, 50 ADET …
Nalmefene, a 6-methylene analogue of naltrexone, is an opioid receptor antagonist. It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence. Nalmefene...
Approved
Investigational
Withdrawn
Matched Description: … [L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist …
Matched Products: … SELINCRO 18MG FILM KAPLI TABLET ,42 TABLET ... SELINCRO 18MG FILM KAPLI TABLET ,7 TABLET ... SELINCRO 18MG FILM KAPLI TABLET ,TABLET, 28 ADET …
Ponatinib is a novel Bcr-Abl tyrosine kinase inhibitor that is especially effective against the T315I mutation for the treatment of chronic myeloid leukemia. FDA approved on December 14, 2012.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ICLUSIG FILM-COATED TABLET 45 MG ... ICLUSIG FILM-COATED TABLET 15 MG ... ICLUSIG 15 MG FILM-COATED TABLETS …
Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Approved
Investigational
Matched Description: … Tolterodine acts on M2 and M3 subtypes of muscarinic receptors. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … TOLTEX 2 MG FILM TABLET, 28 ADET ... TOLTEX FİLM 1 MG TABLET , 28 ADET ... URIDYN 1 MG FILM TABLET ,28 ADET …
Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
Approved
Investigational
Matched Description: … Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and ... enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Fluorouracil and prodrugs ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … KAPETRAL FILM-COATED TABLET 500MG ... KAPETRAL FILM-COATED TABLET 150MG ... XELODA (500 MG FILM-COATED TABLETS) …
The chemical compound calcium acetate is the calcium salt of acetic acid. It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Approved
Investigational
Matched Description: … The chemical compound calcium acetate is the calcium salt of acetic acid. …
Matched Mixtures name: … OSVAREN 435 MG/235 MG 180 FILM KAPLI TABLET …
Matched Categories: … Calcium Salts ... Alimentary Tract and Metabolism ... ascorbic acid (vit C) and calcium ... calcium acetate and magnesium carbonate ... Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … FOSFAT-EX 700 MG FILM TABLET,FILM TABLET, 100 ADET ... FIX-AT 475MG FILM KAPLI TABLET, 90 ADET ... FIX-AT 950 MG FILM KAPLI TABLET, 90 ADET …
Fesoterodine is an antimuscarinic prodrug for the treatment of overactive bladder syndrome.
Approved
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … FOSETAZ 4 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 14 ADET ... FOSETAZ 4 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 28 ADET ... FOSETAZ 4 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 84 ADET …
Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.[A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affect cortisol, aldosterone, and thyroxine. Letrozole was granted FDA approval on 25 July 1997.
Approved
Investigational
Matched Description: … ], meaning it does not significantly affect cortisol, aldosterone, and thyroxine. ... [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Letara Film Coated Tablet 2.5mg ... Trozet Film Coated Tablet 2.5mg ... FEMARA 2.5MG FILM-COATED TABLET …
Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor...
Approved
Matched Description: … A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and ... alternative to non-selective β-blocker drugs in the treatment of hypertension such as [Carvedilol] and ... It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful …
Matched Mixtures name: … KARDORITM PLUS 10 MG/25 MG FILM TABLET ,FILM TABLET, 30 ADET ... Cosyrel 5mg/5mg film-coated tablets ... COSYREL FILM-COATED TABLET 5 mg/ 5 mg …
Matched Categories: … Beta Blocking Agents and Thiazides ... ramipril and bisoprolol ... bisoprolol and thiazides ... perindopril and bisoprolol ... bisoprolol and amlodipine …
Matched Products: … Concor 5mg Film coated Tablet ... Concor 10mg Film coated Tablet ... BISOPRO FILM-COATED TABLET 2.5MG …
Valganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections. As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.
Approved
Investigational
Matched Description: … After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases …
Matched Categories: … Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … Valcivir 450mg Film Coated Tablet ... CITOVIR 450 MG FILM TABLET, 60 ADET ... VALCYTE 450 MG FILM TABLET, 60 ADET …
Displaying drugs 876 - 900 of 1086 in total