Displaying drugs 901 - 925 of 2406 in total
Enoxolone
Enoxolone (glycyrrhetic acid) has been investigated for the basic science of Apparent Mineralocorticoid Excess (AME).
Investigational
Matched Synonyms: … Glycyrrhetic Acid …
Matched Iupac: … 9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid …
Matched Description: … Enoxolone (glycyrrhetic acid) has been investigated for the basic science of Apparent Mineralocorticoid …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …
Matched Iupac: … 9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid …
Matched Description: … Enoxolone (glycyrrhetic acid) has been investigated for the basic science of Apparent Mineralocorticoid …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …
ADU-S100
ADU-S100 (MIW815) is a synthetic cyclic dinucleotide (CDN) agonist (activator) of Stimulator of Interferon Genes (STING), a receptor crucial to activate the innate (endogenous) immune system. ADU-S100 (MIW815) activates all known human and mouse STINGs, and effectively induces the expression of cytokines and chemokines, leading to a robust and durable...
Investigational
Matched Synonyms: … ADU-S100 free acid …
Matched Description: … ADU-S100 (MIW815) activates all known human and mouse STINGs, and effectively induces the expression ... of cytokines and chemokines, leading to a robust and durable antigen-specific T-cell mediated immune …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … ADU-S100 (MIW815) activates all known human and mouse STINGs, and effectively induces the expression ... of cytokines and chemokines, leading to a robust and durable antigen-specific T-cell mediated immune …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Poly(lactic acid)
Poly(lactic acid) is under investigation in clinical trial NCT00126308 (Facial Lipoatrophy Trial: Immediate Versus Deferred Injections of Poly-L-Lactic Acid for HIV Facial Lipoatrophy).
Investigational
Matched Synonyms: … POLY-L-LACTIC ACID …
Matched Name: … Poly(lactic acid) …
Matched Description: … Versus Deferred Injections of Poly-L-Lactic Acid for HIV Facial Lipoatrophy). ... Poly(lactic acid) is under investigation in clinical trial NCT00126308 (Facial Lipoatrophy Trial: Immediate …
Matched Name: … Poly(lactic acid) …
Matched Description: … Versus Deferred Injections of Poly-L-Lactic Acid for HIV Facial Lipoatrophy). ... Poly(lactic acid) is under investigation in clinical trial NCT00126308 (Facial Lipoatrophy Trial: Immediate …
Isosteviol
Investigational
Matched Synonyms: … Ketoisostevic acid …
Matched Iupac: … 4S,5R,9S,10R,13S)-5,9,13-trimethyl-14-oxotetracyclo[11.2.1.0^{1,10}.0^{4,9}]hexadecane-5-carboxylic acid …
Matched Iupac: … 4S,5R,9S,10R,13S)-5,9,13-trimethyl-14-oxotetracyclo[11.2.1.0^{1,10}.0^{4,9}]hexadecane-5-carboxylic acid …
HEPES
Investigational
Matched Synonyms: … 4-(2-Hydroxyethyl)-1-piperazineethane sulfonic acid ... 4-(2-Hydroxyethyl)-1-piperazineethane sulphonic acid …
Matched Iupac: … 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethane-1-sulfonic acid …
Matched Categories: … Sulfur Acids ... Sulfonic Acids ... Alkanesulfonic Acids …
Matched Iupac: … 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethane-1-sulfonic acid …
Matched Categories: … Sulfur Acids ... Sulfonic Acids ... Alkanesulfonic Acids …
Tefidsogene civaparvovec
Tefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing. It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes. Developed by Sangamo...
Experimental
Matched Synonyms: … IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS EXONS 2-9 FROM HIDS AND …
Matched Description: … It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system …
Matched Description: … It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system …
3alpha,6beta,7beta,12alpha-tetrahydroxy-5beta-cholan-24-oic acid
Investigational
Matched Synonyms: … 3a,6b,7b,12a-(OH)4-5b-cholanic acid ... (3α,5β,6β,7β,12α)-3,6,7,12-Tetrahydroxycholan-24-oic acid ... 3alpha,6beta,7beta,12alpha-Tetrahydroxy-5beta-cholanoic acid …
Matched Name: … 3alpha,6beta,7beta,12alpha-tetrahydroxy-5beta-cholan-24-oic acid …
Matched Iupac: … 4-{4,5,7,11-tetrahydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl}pentanoic acid …
Matched Name: … 3alpha,6beta,7beta,12alpha-tetrahydroxy-5beta-cholan-24-oic acid …
Matched Iupac: … 4-{4,5,7,11-tetrahydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl}pentanoic acid …
Arginine
An essential amino acid that is physiologically active in the L-form.
Investigational
Nutraceutical
Matched Synonyms: … (S)-2-Amino-5-guanidinovaleric acid ... (2S)-2-amino-5-guanidinopentanoic acid ... (S)-2-amino-5-guanidinopentanoic acid …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid …
Matched Description: … An essential amino acid that is physiologically active in the L-form. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... arginine and lysine ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Amino Acids …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid …
Matched Description: … An essential amino acid that is physiologically active in the L-form. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... arginine and lysine ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Amino Acids …
Alitretinoin
An important regulator of gene expression during growth and development, and in neoplasms. Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic. It is used in the treatment of psoriasis; acne vulgaris;...
Approved
Investigational
Matched Synonyms: … 9(Z)-Retinoic acid ... 9-cis-retinoic acid ... (7E,9Z,11E,13E)-retinoic acid …
Matched Iupac: … (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid …
Matched Description: … Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth ... An important regulator of gene expression during growth and development, and in neoplasms. ... ; and embryonic development. …
Matched Categories: … Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Matched Iupac: … (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid …
Matched Description: … Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth ... An important regulator of gene expression during growth and development, and in neoplasms. ... ; and embryonic development. …
Matched Categories: … Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
6-hydroxynorleucine
Experimental
Matched Synonyms: … 2-Amino-6-hydroxycaproic acid ... alpha-Amino-epsilon-hydroxycaproic acid …
Matched Iupac: … (2S)-2-amino-6-hydroxyhexanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … (2S)-2-amino-6-hydroxyhexanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Eprodisate
Eprodisate slows the decline of renal function in AA amyloidosis.
Investigational
Matched Synonyms: … 1,3-propanedisulfonic acid ... Propane-1,3-disulfonic acid …
Matched Iupac: … propane-1,3-disulfonic acid …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Matched Iupac: … propane-1,3-disulfonic acid …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Monoctanoin
Monoctanoin is used to dissolve cholesterol gallstones.
Experimental
Matched Synonyms: … Caprylic acid α-monoglyceride ... Octanoic acid 1-monoglyceride …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids …
Sulisobenzone
Sulisobenzone is approved by the FDA in concentrations of up to 10% and in Canada, is approved by Health Canada at the same concentrations . It works to filter out both UVA and UVB rays, protecting the skin from sun UV damage .
The UV-filter substance, sulisobenzone (BP-4) is widely...
Experimental
Matched Synonyms: … 2-benzoyl-5-methoxy-1-phenol-4-sulfonic acid ... 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid ... 3-benzoyl-4-hydroxy-6-methoxybenzenesulfonic acid …
Matched Iupac: … 5-benzoyl-4-hydroxy-2-methoxybenzene-1-sulfonic acid …
Matched Description: … pharmaceuticals and as an additive for plastics, coatings, and adhesives [L2670]. ... Sulisobenzone is approved by the FDA in concentrations of up to 10% and in Canada, is approved by Health ... It works to filter out both UVA and UVB rays, protecting the skin from sun UV damage [L2153]. …
Matched Iupac: … 5-benzoyl-4-hydroxy-2-methoxybenzene-1-sulfonic acid …
Matched Description: … pharmaceuticals and as an additive for plastics, coatings, and adhesives [L2670]. ... Sulisobenzone is approved by the FDA in concentrations of up to 10% and in Canada, is approved by Health ... It works to filter out both UVA and UVB rays, protecting the skin from sun UV damage [L2153]. …
Methionine
A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Approved
Nutraceutical
Matched Synonyms: … L-a-Amino-g-methylthiobutyric acid ... (S)-2-amino-4-(methylthio)butanoic acid ... (S)-2-amino-4-(methylthio)butyric acid …
Matched Iupac: … (2S)-2-amino-4-(methylsulfanyl)butanoic acid …
Matched Description: … A sulfur containing essential amino acid that is important in many body functions. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Men's Biomultiple Vitamin and Mineral Supplement …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Essential ... Amino Acids, Sulfur …
Matched Iupac: … (2S)-2-amino-4-(methylsulfanyl)butanoic acid …
Matched Description: … A sulfur containing essential amino acid that is important in many body functions. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Men's Biomultiple Vitamin and Mineral Supplement …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Essential ... Amino Acids, Sulfur …
TPMPA
TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABAC receptors (also known as GABA-ρ or GABAA-ρ receptors). GABAC receptors are found primarily in the retina, although they may be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and the gut.[A245308,A245313] TPMPA is used as a pharmacological...
Experimental
Matched Synonyms: … (1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid ... P-Methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)phosphinic acid ... Phosphinic acid, P-methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)- …
Matched Iupac: … methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid …
Matched Description: … TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABA ... be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and …
Matched Iupac: … methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid …
Matched Description: … TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABA ... be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and …
Elapegademase
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND ... 356)-PEPTIDE, PRODUCED IN ESCHERICHIA COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND …
Matched Description: … as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …
Matched Description: … as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …
Fluticasone propionate
Fluticasone propionate is a synthetic glucocorticoid[F4355,F4358][FDA Label]. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications[F4355,F4358][FDA Label]. Fluticasone propionate was first approved in 1990 .
Approved
Matched Description: … These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory …
Matched Mixtures name: … Fluticasone Propionate and Salmeterol ... Fluticasone Propionate and Salmeterol ... Fluticasone Propionate and Salmeterol …
Matched Products: … Up and Up Allergy Relief Nasal ... Up and Up allergy relief nasal ... Berkley and Jensen Allergy Relief …
Matched Mixtures name: … Fluticasone Propionate and Salmeterol ... Fluticasone Propionate and Salmeterol ... Fluticasone Propionate and Salmeterol …
Matched Products: … Up and Up Allergy Relief Nasal ... Up and Up allergy relief nasal ... Berkley and Jensen Allergy Relief …
Alanine
Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and the central nervous system.
Nutraceutical
Matched Synonyms: … (2S)-2-aminopropanoic acid ... (S)-2-aminopropanoic acid ... L-2-Aminopropionic acid …
Matched Iupac: … (2S)-2-aminopropanoic acid …
Matched Description: … It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue ... , brain, and the central nervous system. ... Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Proteinogenic Amino Acids …
Matched Iupac: … (2S)-2-aminopropanoic acid …
Matched Description: … It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue ... , brain, and the central nervous system. ... Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Proteinogenic Amino Acids …
Alglucosidase alfa
Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Synonyms: … Acid maltase ... Acid-alpha glucosidase ... Human acid precursor alpha-glucosidase, recombinant …
Matched Description: … Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the ... It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients. ... glycoprotein with a calculated mass of 98,008 daltons for the 883 residue mature polypeptide chain, and …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the ... It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients. ... glycoprotein with a calculated mass of 98,008 daltons for the 883 residue mature polypeptide chain, and …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
NM-004
Investigational
Matched Synonyms: … 5-(4-carboxymethyl-phenylazo)-2-hydroxy-benzoic acid ... 5-((e)-(4-(carboxymethyl)phenyl)azo)-2-hydroxy-benzoic acid ... Benzeneacetic acid, 4-(2-(3-carboxy-4-hydroxyphenyl)diazenyl)- …
Matched Iupac: … 5-[(1E)-2-[4-(carboxymethyl)phenyl]diazen-1-yl]-2-hydroxybenzoic acid …
Matched Iupac: … 5-[(1E)-2-[4-(carboxymethyl)phenyl]diazen-1-yl]-2-hydroxybenzoic acid …
SGS-742
SGS-742 has been used in trials studying the treatment of Seizures and Metabolic Disease.
Investigational
Matched Synonyms: … 3-Aminopropyl-Butyl Phosphinic Acid ... (3-Aminopropyl)(n-butyl)phosphinic acid …
Matched Iupac: … (3-aminopropyl)(butyl)phosphinic acid …
Matched Description: … SGS-742 has been used in trials studying the treatment of Seizures and Metabolic Disease. …
Matched Iupac: … (3-aminopropyl)(butyl)phosphinic acid …
Matched Description: … SGS-742 has been used in trials studying the treatment of Seizures and Metabolic Disease. …
Fluciclovine
Fluciclovine is under investigation in clinical trial NCT03036943 (Fluciclovine (18F) Imaging of Breast Cancer).
Investigational
Matched Synonyms: … Anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid ... Cyclobutanecarboxylic acid, 1-amino-3-fluoro-, trans- …
Matched Iupac: … (1r,3r)-1-amino-3-fluorocyclobutane-1-carboxylic acid …
Matched Iupac: … (1r,3r)-1-amino-3-fluorocyclobutane-1-carboxylic acid …
D-Erythro-2,3-diaminobutyric acid
Experimental
Matched Synonyms: … (2R,3R)-2,3-Diaminobutanoic acid …
Matched Name: … D-Erythro-2,3-diaminobutyric acid …
Matched Iupac: … (2R,3R)-2,3-diaminobutanoic acid …
Matched Name: … D-Erythro-2,3-diaminobutyric acid …
Matched Iupac: … (2R,3R)-2,3-diaminobutanoic acid …
Ceftiofur
Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product. It is resistant to hydrolysis by beta-lactamase, and has activity...
Vet approved
Matched Synonyms: … Ceftiofur crystalline free acid …
Matched Iupac: … acetamido]-3-[(furan-2-carbonylsulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It is resistant to hydrolysis by beta-lactamase, and has activity against both Gram-positive and Gram-negative ... Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary ... It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's …
Matched Iupac: … acetamido]-3-[(furan-2-carbonylsulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It is resistant to hydrolysis by beta-lactamase, and has activity against both Gram-positive and Gram-negative ... Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary ... It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's …
Phenibut
Experimental
Matched Synonyms: … 4-amino-3-phenylbutyric acid …
Matched Iupac: … 4-amino-3-phenylbutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hypnotics and Sedatives ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
Matched Iupac: … 4-amino-3-phenylbutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hypnotics and Sedatives ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
Displaying drugs 901 - 925 of 2406 in total