Displaying drugs 926 - 950 of 1207 in total
Alprostadil
Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment...
Approved
Investigational
Matched Description: … intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and ... This drug causes vasodilation by directly affecting vascular and ductus arteriosus (DA) smooth muscle …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Alprostadil Altan 20 Mikrogramm - Pulver zur Herstellung einer Infusionslösung ... Alprostadil Altan Pharma 20 Mikrogramm - Pulver zur Herstellung einer Infusionslösung …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Alprostadil Altan 20 Mikrogramm - Pulver zur Herstellung einer Infusionslösung ... Alprostadil Altan Pharma 20 Mikrogramm - Pulver zur Herstellung einer Infusionslösung …
Muplestim
Muplestim is under investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients With Cytopenia).
Investigational
Matched Synonyms: … Interleukin 3 (human) ... Human interleukin-3 (nonglycosylated) ... Interleukin-3 human (recombinant) …
Matched Description: … investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and ... Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and ... Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Human Menstrual Blood-derived Stem Cells
Stem cells are self-renewing and proliferate without differentiation, with the two major groups being embryonic stem cells (ESCs) and adult stem cells (ASC). Differentiation occurs under different conditions into different cell types. ESCs are from the inner cell mass of blastocysts while ASCs are deposited into adult tissues with restricted...
Investigational
Matched Name: … Human Menstrual Blood-derived Stem Cells …
Matched Description: … embryonic stem cells (ESCs) and adult stem cells (ASC). ... Stem cells are self-renewing and proliferate without differentiation, with the two major groups being ... These cells possess a high rate of proliferation and multi-lineage differentiation potency. …
Matched Description: … embryonic stem cells (ESCs) and adult stem cells (ASC). ... Stem cells are self-renewing and proliferate without differentiation, with the two major groups being ... These cells possess a high rate of proliferation and multi-lineage differentiation potency. …
Human Embryonic Stem Cell-derived Astrocytes
Investigational
Matched Name: … Human Embryonic Stem Cell-derived Astrocytes …
Recombinant human palmitoyl protein thioesterase-1
Investigational
Matched Name: … Recombinant human palmitoyl protein thioesterase-1 …
ATYR-1940
Investigational
Matched Synonyms: … Human recombinant histidyl-t-RNA synthetase (residues 2-506) …
.gamma.-brain natriuretic peptide
Investigational
Matched Synonyms: … Natriuretic peptides b (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Bleomycin
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Approved
Investigational
Matched Description: … of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and ... It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Bleomycin Accord 15.000 IE Pulver zur Herstellung einer Injektions-/Infusionslösung …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Bleomycin Accord 15.000 IE Pulver zur Herstellung einer Injektions-/Infusionslösung …
Amatuximab
Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(mesothelin) (human-mouse monoclonal MORAb-009 heavy chain), disulfide with human-mouse …
Matched Description: … Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian ... Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian ... Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dapiclermin
Dapiclermin is a recombinant ciliary neurotrophic factor.
Investigational
Matched Synonyms: … 2-185-ciliary neurotrophic factor (17 -alanine,63-arginine) (human isoform axokine) ... 2-185-(17-alanine,63-agrinine)ciliary neurotrophic factor-(2,185)-peptide (human isoform axokine) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
INVAC-1
INVAC-1 is under investigation in clinical trial NCT03265717 (DNA Plasmid Encoding a Modified Human Telomerase Reverse Transcriptase (Htert), Invac-1 in Chronic Lymphocytic Leukemia).
Investigational
Matched Synonyms: … Human telomerase reverse transcriptase (htert) dna vaccine invac-1 ... Invac-1, a double stranded dna plasmid vaccine construct encoding ubiquitin-human telomerase reverse …
Matched Description: … INVAC-1 is under investigation in clinical trial NCT03265717 (DNA Plasmid Encoding a Modified Human Telomerase …
Matched Description: … INVAC-1 is under investigation in clinical trial NCT03265717 (DNA Plasmid Encoding a Modified Human Telomerase …
Cotoretigene toliparvovec
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 8 containing the human RPGR gene ... Adenovirus-associated viral vector serotype 8 containing the human RPGR gene …
Sevirumab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(CYTOMEGALOVIRUS) (HUMAN MONOCLONAL EV2-7 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dazukibart
Investigational
Matched Synonyms: … β) (human-Mus musculus monoclonal PF-06823859 γ1-chain), disulfide with human-Mus musculus monoclonal ... Immunoglobulin G1 [236-alanine,237-alanine,239-alanine,de-C-terminal-lysine], anti-(human interferon ... humanized monoclonal antibody (immunoglobulin gamma-1 with kappa light chains, IgG1kappa) directed against human …
Efruxifermin
Efruxifermin is under investigation in clinical trial NCT06215716 (A Study Evaluating Efruxifermin in Subjects With Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and Fibrosis).
Investigational
Matched Synonyms: … factor 21 (98-arginine,171-glycine,180-glutamic acid) (human mutant clone amg876) ... Immunoglobulin g (synthetic human constant domain fc fragment) fusion protein with fibroblast growth ... Immunoglobulin g1 (human .gamma.1-chain c-region c-terminal fragment) fusion protein with peptide linker …
Matched Description: … Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Pariglasgene brecaparvovec
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 8 containing the human glucose-6-phosphatase gene ... Recombinant adeno-associated virus serotype 8 vector encoding human glucose-6-phosphatase-alpha ... Recombinant adeno-associated virus serotype 8 vector encoding human glucose-6-phosphatase-alpha (G6Pase …
Ifinatamab deruxtecan
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN B7 HOMOLOG 3 PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .GAMMA ... .1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .KAPPA. …
Ripertamab
Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated Cd20(cluster of Differentiation Antigen 20)-positive DLBCL Patients).
Investigational
Matched Synonyms: … Immunoglobulin igg1, anti-(human cd20 antigen) (human-mus musculus monoclonal disulfide sct400 .gamma ... .1-chain), disulfide with human-mus musculus monoclonal sct400 .kappa. …
Matched Description: … Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and ... Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated …
Matched Description: … Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and ... Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated …
Sirexatamab
Investigational
Matched Synonyms: … Immunoglobulin g4 (224-proline,233-alanine,234-alanine), anti-(human dickkopf-1) (human-mus musculus ... monoclonal dkn-01 .gamma.4-chain), disulfide with human-mus musculus monoclonal dkn-01 .kappa. …
Teriparatide
Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Synonyms: … Teriparatide recombinant human …
Matched Description: … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] ... [A251395] Teriparatide is used in the treatment of osteoporosis in men and women.[L42590, L42595] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Calcium-Regulating Hormones and Agents ... Parathyroid Hormones and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] ... [A251395] Teriparatide is used in the treatment of osteoporosis in men and women.[L42590, L42595] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Calcium-Regulating Hormones and Agents ... Parathyroid Hormones and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Mirococept
Mirococept (APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and I/RI. It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct that regulates the over-production of complement at the cell surface, which occurs in inflammation. It consists...
Investigational
Matched Synonyms: … myristoylated recombinant SCR1-3 of human complement reseptor type I …
Matched Description: … APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and ... in recombinant bacteria and modified with a membrane-targeting amphiphilic peptide based on the naturally ... It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct …
Matched Description: … APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and ... in recombinant bacteria and modified with a membrane-targeting amphiphilic peptide based on the naturally ... It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct …
Eptacog alfa pegol (activated)
Eptacog alfa pegol (activated) has been used in trials studying the prevention and treatment of Haemophilia A, Haemophilia B, Congenital Bleeding Disorder, Haemophilia B With Inhibitors, and Haemophilia A With Inhibitors.
Investigational
Matched Synonyms: … Activated Recombinant Human Factor VII, Long Acting …
Matched Description: … Eptacog alfa pegol (activated) has been used in trials studying the prevention and treatment of Haemophilia ... A, Haemophilia B, Congenital Bleeding Disorder, Haemophilia B With Inhibitors, and Haemophilia A With …
Matched Description: … Eptacog alfa pegol (activated) has been used in trials studying the prevention and treatment of Haemophilia ... A, Haemophilia B, Congenital Bleeding Disorder, Haemophilia B With Inhibitors, and Haemophilia A With …
Velmanase alfa
Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme alpha-mannosidase, which is an enzyme responsible for breaking down complex...
Approved
Investigational
Matched Synonyms: … Recombinant Human Alpha Mannosidase …
Matched Description: … sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and ... deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Recombinant Human Lysosomal alpha-Mannosidase …
Matched Description: … sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and ... deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Recombinant Human Lysosomal alpha-Mannosidase …
Vonicog alfa
Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. It was FDA approved in December 2015. The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg. By the EMA, vonicog alfa is still under clinical analysis.
Approved
Investigational
Matched Synonyms: … Von willebrand factor, recombinant, human …
Matched Description: … [A32230] The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg …
Matched Description: … [A32230] The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg …
Pegilodecakin
Pegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer).
Investigational
Matched Synonyms: … INTERLEUKIN 10 (SYNTHETIC HUMAN), DIMER, N-TERMINAL 5-KILODALTON PEGYLATED …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Displaying drugs 926 - 950 of 1207 in total