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Displaying drugs 926 - 950 of 1334 in total

Voriconazole

Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha sterol demethylase...
Approved
Matched Description: … These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. ... The increased affinity of voriconazole for 14-alpha sterol demethylase makes it useful against some [ …
Matched Categories: … Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances ... Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … VFEND (200 MG POWDER FOR SOLUTION FOR INFUSION ... VORICONAZOLE ALVOGEN (200 MG POWDER FOR SOLUTION FOR INFUSION) ... Voriconazole ADVAGEN powder for solution for infusion 200mg …

Artesunate

Artesunate is indicated for the initial treatment of severe malaria. The World Health Organization recommends artesunate as first line treatment for severe malaria. Artesunate was developed out of a need for a more hydrophilic derivative of artemisinin. Artesunate was granted FDA approval on 26 May 2020.
Approved
Investigational
Matched Description: … Artesunate is indicated for the initial treatment of severe malaria. ... [L890] Artesunate was developed out of a need for a more hydrophilic derivative of [artemisinin]. ... [L14099] The World Health Organization recommends artesunate as first line treatment for severe malaria …
Matched Categories: … Artemisinin and derivatives ... artesunate and mefloquine ... artesunate and amodiaquine ... artesunate and pyronaridine ... artesunate, sulfalene and pyrimethamine …
Matched Products: … ARTESUNATE FOR INJECTION ... ARTESUN POWDER FOR INJECTION 60 MG …

Eribulin

Eribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic disease. Eribulin was isolated from the marine sponge Halichondria okadai. Eribulin is also being investigated for use in the treatment of...
Approved
Investigational
Matched Description: … Eribulin is also being investigated for use in the treatment of advanced solid tumors [A7439]. ... Eribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer ... who have previously received at least two chemotherapeutic regimens for the treatment of metastatic …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Halaven Solution for Injection 0.5mg/mL ... HALAVEN 0.5 mg/ml solution for injection …

Choriogonadotropin alfa

Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha-chain of r-hCG is identical...
Approved
Matched Description: … O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER ... -121, SER-127, SER-132 and SER-138 (on beta subunit). ... human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Sex Hormones and Modulators of the Genital System …
Matched Products: … Ovidrel Solution for Injection 250 mcg ... OVIDREL 250MCG/0.5ML SOLUTION FOR INJECTION …

Ixekizumab

Ixekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) against interleukin-17A (IL-17A) and prevents it from interacting with the IL-17A receptor. As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions. In particular, IL-17A has...
Approved
Investigational
Matched Description: … heavy chain polypeptides of 445 amino acids each, and has a molecular weight of 146,158 Daltons for ... for systemic therapy or phototherapy. ... using standard technology for bioprocessing. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Taltz 80mg solution for injection in pre-filled pen ... Taltz 80mg solution for injection in pre-filled syringe ... TALTZ SOLUTION FOR INJECTION IN PRE-FILLED PEN 80 mg/ml …

Pyridoxal

The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. [PubChem]
Experimental
Nutraceutical
Matched Synonyms: … 2-methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine …
Matched Description: … The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme ... for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic …

Etanercept

Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Description: … [L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region ... variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Biologics for Rheumatoid Arthritis Treatment …
Matched Products: … ENBREL FOR INJECTION 25 mg/vial ... Enbrel Solution for Injection in a Pre-filled Pen 50mg ... Eucept 50 mg / mL Solution for Injection in Pre-filled Syringe …

Piperacillin

Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Approved
Matched Description: … Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas …
Matched Mixtures name: … Piperacillin and Tazobactam for Injection ... Piperacillin and Tazobactam for Injection ... Piperacillin and Tazobactam for Injection …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … PIPERACILLIN/TAZOBACTAM KABI POWDER FOR SOLUTION FOR INFUSION 4G/0.5G ... Piperacillin for Injection …

Romiplostim

Romiplostim is a thrombopoiesis stimulating dimer Fc-peptide fusion protein (peptibody) to increase platelet production through activation of the thrombopoietin receptor. The peptibody molecule has two identical single-chain subunits, each one is made up of 269 amino acid residues. Each subunit consists of an IgG1 Fc carrier domain that is covalently...
Approved
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Products: … ROMIPLATE POWDER FOR SOLUTION FOR INJECTION 250 ?g/vial …

Rituximab

Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences , [FDA label]. It was originally...
Approved
Matched Description: … sequences and human constant region sequences [A40017], [FDA label]. ... to treat patients with B-cell Non-Hodgkin's Lymphoma (NHL) [L4811], however, has now been approved for ... The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Biologics for Rheumatoid Arthritis Treatment ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … Mabthera Vials 10mg/ml Concentreate For Solution For Infusion ... TRUXIMA® CONCENTRATE FOR SOLUTION FOR INFUSION 10MG/ML ... Mabthera Concentrate for Solution for Infusion 100mg/10ml …

Daptomycin

Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Description: … -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE). ... with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and ... [A231379] Daptomycin was approved by the FDA on September 12, 2003, and is marketed under the name …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … DAPTOCCORD 500 POWDER FOR SOLUTION FOR INJECTION OR INFUSION 500 MG/VIAL ... Daptomycin for Injection ... Daptomycin for Injection RF …

Norepinephrine

Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Description: … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic ... It is also found in plants and is used pharmacologically as a sympathomimetic. ... Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse …
Matched Categories: … Epinephrine and similars ... Adrenergic and Dopaminergic Agents ... Alpha-and Beta-adrenergic Agonists …
Matched Products: … N-EPI® 1mg/ml Concentrate for Solution for Infusion ... NORADRENALINE AGUETTANT 1MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION ... Noradrenaline Sintetica 1mg/ml Concentrate for Solution for Infusion …

Palivizumab

Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV). Synagis is a composite of human (95%) and murine (5%) antibody sequences. The human heavy chain sequence was derived from the constant domains...
Approved
Investigational
Matched Description: … regions of the VH genes Cor (1) and Cess (2). ... Synagis is a composite of human (95%) and murine (5%) antibody sequences. ... 1-2% carbohydrate by weight and has a molecular weight of 147.7 kDa +/- 1 kDa (MALDI-TOF) …
Matched Categories: … Antiinfectives for Systemic Use ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Products: … Synagis 100mg/ml solution for Injection ... SYNAGIS SOLUTION FOR INJECTION 100MG/ML ... SYNAGIS STERILE POWDER FOR INJECTION 100 mg/vial …

Montmorillonite

Experimental
Investigational
Matched Mixtures name: … SEED Teatree and Lime Vegan No-sebum Cool Anti HairlossShampoo …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … DIMECTAL Powder for Oral Suspension 3g ... Smecta Strawberry Flavour Powder for Oral Suspension 3g ... Smecta Orange-Vanilla Flavour Powder for Oral Suspension 3g …

Nifuroxazide

Experimental
Matched Mixtures name: … METRO FORT …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … DIAFURYL FORT 200 MG KAPSÜL, 16 ADET ... DIAFURYL FORT 200 MG KAPSÜL, 24 ADET …

Satralizumab

Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to tocilizumab, which is produced in Chinese hamster ovary cells and based on an IgG2 framework. Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central...
Approved
Matched Description: … [A218551] It received subsequent approvals in Switzerland and Japan,[A218551] and was approved for use ... Satralizumab was first approved for use in Canada in June 2020 for the treatment of AQP4 antibody-positive ... [eculizumab] in June 2019 and [inebilizumab] in June 2020). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ENSPRYNG SOLUTION FOR INJECTION IN PREFILLED SYRINGE 120MG/1ML ... ENSPRYNG 120 mg/1ml solution for injection in pre-filled syringe …

Imiglucerase

Human Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD. Alglucerase is prepared by modification of the oligosaccharide chains of human Beta-glucocerebrosidase. The modification alters the sugar residues at the non-reducing ends of the oligosaccharide chains of the glycoprotein so that they are predominantly terminated...
Approved
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Products: … (Imiglucerase) 400U Powder for solution for injection …

Nivolumab

Nivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation S228P for additional stability and reduced variability. It was developed by Bristol Myers Squibb. Nivolumab was...
Approved
Matched Description: … with the mutation _S228P_ for additional stability and reduced variability. ... [L12129] This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region …
Matched Categories: … Amino Acids, Peptides, and Proteins ... nivolumab and relatlimab ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … Opdivo 10mg/ml, Concentrate for solution for infusion ... OPDIVO CONCENTRATE FOR SOLUTION FOR INFUSION 10 MG/ML ... NIVOLUMAB BMS CONCENTRATE FOR SOLUTION FOR INFUSION 10MG/ML …

Carfilzomib

Carfilzomib is an injectable antineoplastic agent (IV only). Chemically, it is a modified tetrapeptidyl epoxide and an analog of epoxomicin. It is also a selective proteasome inhibitor. FDA approved carfilzomib in July 2012 for the treatment of adults with relapsed or refractory multiple myeloma as monotherapy or combination therapy.
Approved
Investigational
Matched Description: … Chemically, it is a modified tetrapeptidyl epoxide and an analog of epoxomicin. ... FDA approved carfilzomib in July 2012 for the treatment of adults with relapsed or refractory multiple …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … KYPROLIS POWDER FOR SOLUTION FOR INFUSION 60MG/VIAL ... KYPROLIS POWDER FOR SOLUTION FOR INFUSION 30 MG/VIAL ... Kyprolis (carfilzomib) powder for solution for infusion 60mg/vial …

Hepatitis B immune globulin

Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines. According to the Centers for Disease Control...
Approved
Investigational
Matched Description: … The preparation is tested for absence of HIV, HCV, herpes virus, and reovirus. ... According to the Centers for Disease Control and Prevention (CDC), the hepatitis B vaccine was the first ... During the process, viruses are deactivated, and in the final steps, solvents used in the preparation …
Matched Categories: … Antiinfectives for Systemic Use ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Products: … HEPATECT CP SOLUTION FOR INFUSION 50 IU/ML ... Niuliva Solution For Infusion 250 I.U./ml ... ZUTECTRA SOLUTION FOR INJECTION 500 IU/ML …

Terlipressin

Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor. It is a prodrug of lypressin, or lysine vasopressin. Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor. As a potent vasopressor, terlipressin has been...
Approved
Investigational
Matched Description: … Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for ... [L43217] As a potent vasopressor, terlipressin has been investigated in various shock states and conditions ... [A2601, A2602, A2603, A2604, A2605] It was also studied in hepatorenal syndrome (HRS) and variceal bleeding …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Vasopressin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … GLYPRESSIN FOR INJECTION 1 mg/vial ... GLYPRESSIN 1mg/8.5ml solution for injection ... GLYPRESSIN solution for injection, 1 mg/8.5 ml …

Velaglucerase alfa

Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease.
Approved
Investigational
Matched Description: … Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of ... Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Products: … VPRIV POWDER FOR SOLUTION FOR INFUSION 400 UNITS/VIAL …

Obexelimab

Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).
Investigational
Matched Synonyms: … XMAB5871 (HUMANIZED ANTI-CD19 ANTIBODY WITH AN FC PORTION ENGINEERED FOR INCREASED AFFINITY (200- TO …

Barium sulfate

Barium sulfate is an inorganic compound with the chemical formula BaSO4 . Barium sulfate occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield . This drug is used as a contrast agent in...
Approved
Matched Description: … bicarbonate to enhance distension of the GI tract, allowing for enhanced gastrointestinal tract visualization ... It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation ... Barium sulfate is ingested by mouth or administered rectally and combined with granules of effervescent …
Matched Products: … Baricon for Suspension ... Barosperse for Susp 95% ... Tonopaque for Suspension 95% …

Eculizumab

Eculizumab is a monoclonal antibody that targets complement protein C5.[L6919,A2245] Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions.[L6919,A2245,A2246] Eculizumab was granted FDA approval on 16 March 2007. In Q1 2023, the EMA's Committee for Medicinal Products...
Approved
Investigational
Matched Description: … [L6919] In Q1 2023, the EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a positive ... opinion of two formulations of eculizumab indicated for the treatment of paroxysmal nocturnal hemoglobinuria …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Soliris Concentrate for Solution for Infusion 300mg/vial …
Displaying drugs 926 - 950 of 1334 in total