Displaying drugs 926 - 950 of 958 in total
Efavaleukin alfa
Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin G Fc domain by way of a G4S linker. It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease).
Investigational
Matched Synonyms: … fragment) fusion protein with peptide (synthetic linker) fusion protein with interleukin 2 (synthetic human …
Matched Description: … It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With …
Matched Description: … It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With …
scAAV9.U7.ACCA
scAAV9.U7.ACCA is a non-replicating recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human DMD gene under the control of U7 small nuclear non-coding RNA. Developed by Nationwide Children’s Hospital, it is being investigated for the treatment of Duchenne muscular dystrophy.
Investigational
Matched Synonyms: … recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human …
Matched Description: … recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human …
Matched Description: … recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human …
Ceftriaxone
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Description: … meninges[A215582], eyes[A215647], and inner ear[A215627]. ... [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the ... Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins …
Matched Products: … Ceftriaxone and Dextrose …
Matched Products: … Ceftriaxone and Dextrose …
Giroctocogene fitelparvovec
Giroctocogene fitelparvovec is under investigation in clinical trial NCT04370054 (Study to Evaluate the Efficacy and Safety of PF-07055480 in Moderately Severe to Severe Hemophilia a Adults).
Investigational
Matched Synonyms: … Dna (recombinant adeno-associated virus 6 vector pf-07055480 human b-domain-deleted blood-coagulation …
Matched Description: … fitelparvovec is under investigation in clinical trial NCT04370054 (Study to Evaluate the Efficacy and …
Matched Description: … fitelparvovec is under investigation in clinical trial NCT04370054 (Study to Evaluate the Efficacy and …
AVID-200
AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein.
Investigational
Matched Synonyms: … Tgf-.beta. ligand trap comprised of tgf-.beta. receptor ectodomains fused to a human fc domain (avid- …
Porgaviximab
Investigational
Matched Synonyms: … with human-mus musculus monoclonal c2g4 .kappa. ... Immunoglobulin g1, anti-(ebolavirus glycoprotein) (human-mus musculus monoclonal c2g4 heavy chain), disulfide …
Prademagene zamikeracel
Investigational
Matched Synonyms: … Ex-vivo-expanded autologous keratinocytes transduced with retroviral vector containing the human COL7A1 …
Linezolid
Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of streptococci. Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically,...
Approved
Investigational
Matched Description: … Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most ... generally more effective and tolerable than its predecessor. ... synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit[A11227,A199050] and …
Matched Products: … LESINOL …
Matched Products: … LESINOL …
Alteplase
Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and fibrin.[A252330,L43125] Alteplase...
Approved
Investigational
Matched Synonyms: … Plasminogen activator (human tissue-type protein moiety) …
Matched Description: … alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and ... thrombolytic agents derived from tissue plasminogen activator, such as [desmoteplase], [tenecteplase] and ... alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and …
Matched Mixtures name: … Lysatec RT - Pa …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Description: … alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and ... thrombolytic agents derived from tissue plasminogen activator, such as [desmoteplase], [tenecteplase] and ... alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and …
Matched Mixtures name: … Lysatec RT - Pa …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Vasoactive intestinal peptide
Investigational
Matched Synonyms: … Vasoactive intestinal peptide (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
MALP-2
Investigational
Matched Synonyms: … L-lysine, s-((2r)-2,3-bis((1-oxohexadecyl)oxy)propyl)-l-cysteinylglycyl-l-asparaginyl-l-asparaginyl-l …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dynorphin
Dynorphin is under investigation in clinical trial NCT00000244 (Effects of Dynorphin 1-13 on Heroin Addiction - 1).
Investigational
Matched Synonyms: … Dynorphin a (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Equecabtagene autoleucel
Investigational
Matched Synonyms: … self-inactivating, non-replicating lentiviral vector encoding a chimeric antigen receptor (CAR) targeting human …
Magnesium hydroxide
Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form.
Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially...
Approved
Investigational
Matched Description: … Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used …
Matched Mixtures name: … Antacid and Antigas ... Mylanta Coat and Cool ... Antacid and Gasrelief …
Matched Categories: … Antacids and Adsorbents ... Alimentary Tract and Metabolism ... Basic Ointments and Protectants ... Aluminum and magnesium containing antacids ... Emollients Demulcents and Protectants …
Matched Products: … Humco Milk of Magnesia …
Matched Mixtures name: … Antacid and Antigas ... Mylanta Coat and Cool ... Antacid and Gasrelief …
Matched Categories: … Antacids and Adsorbents ... Alimentary Tract and Metabolism ... Basic Ointments and Protectants ... Aluminum and magnesium containing antacids ... Emollients Demulcents and Protectants …
Matched Products: … Humco Milk of Magnesia …
Tetracosactide
Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone. ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. Tetracosactide exhibits the same...
Approved
Matched Synonyms: … Adrenocorticotropic hormone fragment 1-24 human, rat …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Nadofaragene firadenovec
Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Synonyms: … Replication-deficient adenovirus type 5 (ad5) vector encoding the human interferon alpha 2 (ifna2, interferon …
Matched Description: … [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. ... firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer across the urothelium and ... firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human …
Matched Categories: … Cellular and Gene Therapy ... Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Matched Description: … [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. ... firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer across the urothelium and ... firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human …
Matched Categories: … Cellular and Gene Therapy ... Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Apamistamab iodine I-131
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human CD45 antigen) (mus musculus monoclonal BC8 gamma1-chain), disulfide with …
Allogenic bone marrow-derived mesenchymal stem cells
Investigational
Matched Synonyms: … Allogeneic bone marrow derived human mesenchymal stem cells …
Piroxicam
A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
Approved
Investigational
Matched Description: … osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. ... non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … STOPEN TABLETAS SOLUBLES …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … STOPEN TABLETAS SOLUBLES …
Acetazolamide
One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is...
Approved
Vet approved
Matched International brands: … Huma-Zolamide …
Matched Description: … (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) ... It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures ... anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Description: … (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) ... It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures ... anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Iodine I-131 monoclonal antibody 81C6
Neuradiab is under investigation in clinical trial NCT00615186 (Glioblastoma Multiforme (GBM) Locoregional Agent Survival Study - Anti-tenascin Radiolabeled Antibody Therapy).
Investigational
Matched Synonyms: … Moab, 81c6, murine, iodine-I-131 radiolabeled, to human glioma …
Varicella zoster vaccine (live/attenuated)
Live attenuated zoster vaccine is available as two products: Zostavax for the prevention of shingles in immunocompetent people over the age of 50, and Varivax for the prevention of chickenpox in individuals 12 months of age and older. While the two vaccines contain the same immunological components and provide protection...
Approved
Matched Synonyms: … Human herpesvirus 3 live (attenuated) antigen …
Matched Description: … efficacy in preventing postherpetic neuralgia in patients 70 years and older and 91% efficacy in patients ... Efficacy for prevention of shingles is highest in patients 60-69 years old and decreases with increasing ... ophthalmicus) or ear, nerve palsies, or spread of VZV to non-immune persons via contact with varicella lesions …
Matched Mixtures name: … PROQUAD® ( Measles, Mumps, Rubella AND Varicella (Oka/Merck) Virus Vaccine Live, MSD) LYOPHILIZED VACCINE …
Matched Description: … efficacy in preventing postherpetic neuralgia in patients 70 years and older and 91% efficacy in patients ... Efficacy for prevention of shingles is highest in patients 60-69 years old and decreases with increasing ... ophthalmicus) or ear, nerve palsies, or spread of VZV to non-immune persons via contact with varicella lesions …
Matched Mixtures name: … PROQUAD® ( Measles, Mumps, Rubella AND Varicella (Oka/Merck) Virus Vaccine Live, MSD) LYOPHILIZED VACCINE …
Mirtazapine
Mirtazapine is a tetracyclic piperazino-azepine antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder.[T595, L6157] The effects of this...
Approved
Matched Description: … prevent nausea and vomiting after surgery. ... ., and received FDA approval in 1997 for the treatment of major depressive disorder. ... symptoms of neurological disorders, reverse weight loss caused by medical conditions, improve sleep, and …
Matched Products: … MIRTAZAPINA HUMAX® TABLETAS RECUBIERTAS …
Matched Products: … MIRTAZAPINA HUMAX® TABLETAS RECUBIERTAS …
Vonlerolizumab
Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-based Therapy).
Investigational
Matched Synonyms: … Immunoglobulin g1-kappa, anti-(human tumor necrosis factor receptor superfamily member 4 (act35 antigen …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 926 - 950 of 958 in total