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Displaying drugs 926 - 950 of 1189 in total

Hydromorphone

Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Description: … Due to these modifications, it presents a very high potency and comparable side effect profile to the ... the absence of a double bond between the carbon 7 and 8. ... was developed by Fresenius Kabi USA and FDA approved in 1984. …
Matched Salts name: … Hydromorphone hydrochloride …
Matched Categories: … hydromorphone and naloxone ... hydromorphone and antispasmodics …
Matched Products: … Hydromorphone Hydrochloride ... Hydromorphone hydrochloride ... HYDROmorphone Hydrochloride …

Terazosin

Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label] . Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate .
Approved
Matched Description: … quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and ... adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and …
Matched Salts name: … Terazosin hydrochloride ... Terazosin hydrochloride hydrate …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Terazosin Hydrochloride ... Terazosin hydrochloride ... Terazosin Hydrochloride Anhydrous …

Pralmorelin

Investigational
Matched Synonyms: … D-alanyl-3-(2-naphthyl)-d-alanyl-l-alanyl-l-tryptophyl-d-phenylalanyl-l-lysinamide ... L-lysinamide, d-alanyl-3-(2-naphthalenyl)-d-alanyl-l-alanyl-l-tryptophyl-d-phenylalanyl- …
Matched Salts name: … Pralmorelin hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Hydroxyzine

Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.[A1257,A187589] It was first developed in 1955, and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. The active metabolite of hydroxyzine,...
Approved
Matched Description: … for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. ... and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. ... [A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment …
Matched Salts name: … Hydroxyzine hydrochloride …
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics ... Histamine Agents ... Histamine Antagonists ... Histamine H1 Antagonists ... Histamine Receptor Antagonists …
Matched Products: … Hydroxyzine hydrochloride ... Hydroxyzine Hydrochloride ... HydrOXYzine hydrochloride …

Cyproheptadine

Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation and its off-label use in the treatment of serotonin syndrome.
Approved
Matched Description: … Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. ... treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation[L32519] and …
Matched Salts name: … Cyproheptadine hydrochloride …
Matched Categories: … Histamine Agents ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Cyproheptadine Hydrochloride ... CYPROHEPTADINE HYDROCHLORIDE ... CYPROHEPTADINE HYDROCHLORIDE SYRUP …

Topotecan

An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Salts name: … Topotecan hydrochloride …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Topotecan hydrochloride ... Topotecan Hydrochloride ... Topotecan Hydrochloride for Injection …

Alfentanil

A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Approved
Illicit
Matched Description: … A short-acting opioid anesthetic and analgesic derivative of fentanyl. ... It produces an early peak analgesic effect and fast recovery of consciousness. ... effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and …
Matched Salts name: … Alfentanil hydrochloride …
Matched Categories: … Fentanyl and fentanyl analogues …
Matched Products: … Alfentanil Hydrochloride …

Hydrogenated soybean lecithin

Experimental
Matched Synonyms: … Glycine max lecithin, hydrogenated …

Inhibitor BEA388

Experimental
Matched Synonyms: … [5-(2-hydroxy-indan-1-ylcarbamoyl)-3,4-dihydroxy-2,5-[dibenzyl-oxy]-pentanoyl]-valinyl-amido-methane …

Naratriptan

Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
Approved
Investigational
Matched Salts name: … Naratriptan hydrochloride …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … Naratriptan Hydrochloride …

Amitriptyline

Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.
Approved
Matched Mixtures name: … Perphenazine and Amitriptyline Hydrochloride ... Perphenazine and Amitriptyline Hydrochloride ... Chlordiazepoxide and Amitriptyline Hydrochloride …
Matched Salts name: … Amitriptyline hydrochloride …
Matched Categories: … amitriptyline and psycholeptics ... Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Amitriptyline Hydrochloride ... Amitriptyline hydrochloride ... AMITRIPTYLINE HYDROCHLORIDE …

Finotonlimab

Finotonlimab is under investigation in clinical trial NCT04560894 (SCT-I10A Plus SCT510 Versus Sorafenib as First-line Therapy for Advanced Hepatocellular Carcinoma).
Investigational
Matched Synonyms: … Immunoglobulin g4 (226-proline), anti-(human programmed cell death 1) (human-mus musculus monoclonal …

Maplirpacept

Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG.
Investigational
Matched Synonyms: … 1-118-Signal regulatory protein α (human) fusion protein with immunoglobulin G4 [128-proline] (human …

Livmoniplimab

Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)).
Investigational
Matched Synonyms: … Immunoglobulin g4 (234-proline), anti-(human protein garp-transforming growth factor .beta.1 complex) …
Matched Description: … Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and …

Raloxifene

Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Description: … uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation. ... generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and ... and it does not cause endometrial proliferation. …
Matched Salts name: … Raloxifene Hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … Raloxifene Hydrochloride ... Raloxifene hydrochloride …

Metoclopramide

Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Matched Description: … Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative ... impact on quality of life and poses a significant burden on the healthcare system. ... [A184934] Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated …
Matched Salts name: … Metoclopramide hydrochloride ... Metoclopramide hydrochloride anhydrous …
Matched Categories: … Alimentary Tract and Metabolism ... Benzamides and benzamide derivatives …
Matched Products: … Metoclopramide Hydrochloride ... METOCLOPRAMIDE hydrochloride ... Metoclopramide hydrochloride …

Ethyl Dimethyl Ammonio Propane Sulfonate

Experimental
Matched Name: … Ethyl Dimethyl Ammonio Propane Sulfonate …
Matched Iupac: … 3-(ethyldimethylazaniumyl)propane-1-sulfonate …

PARA-NITROBENZYL GLUTARYL GLYCINIC ACID

Experimental
Matched Name: … PARA-NITROBENZYL GLUTARYL GLYCINIC ACID …

Benazepril

Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor .
Approved
Investigational
Matched Description: … Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and …
Matched Mixtures name: … Benazepril Hydrochloride and Hydrochlorothiazide ... Benazepril Hydrochloride and Hydrochlorothiazide ... Benazepril Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Benazepril hydrochloride …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... benazepril and amlodipine ... benazepril and diuretics …
Matched Products: … Benazepril Hydrochloride ... Benazepril hydrochloride …

Papaverine

An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear,...
Approved
Investigational
Matched Description: … It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, ... mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and …
Matched Salts name: … Papaverine hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Papaverine and Derivatives …
Matched Products: … Papaverine Hydrochloride ... PAPAVERINE HYDROCHLORIDE ... Papaverine Hydrochloride Injection USP …

Symmetric dimethylarginine

Experimental
Matched Synonyms: … N3,N4-dimethyl-L-arginine …
Matched Categories: … Amino Acids, Peptides, and Proteins …

N-(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)GLYCINE

Experimental
Matched Name: … N-(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)GLYCINE …

2,3-Dimercapto-1-propanesulfonic acid

Experimental
Matched Synonyms: … 2,3-Dimercapto-1-propane sulfonate …

Prilocaine

A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Approved
Matched Mixtures name: … Prilocaine Hydrochloride with Epinephrine ... Lidocaine and Prilocaine ... Lidocaine and Prilocaine …
Matched Salts name: … Prilocaine hydrochloride …
Matched Products: … Prilocaine Hydrochloride ... Dentsply 4% Prilocaine Hydrochloride Dental Injection …

Ragifilimab

Ragifilimab is under investigation in clinical trial NCT04225039 (Anti-gitr/anti-pd1/stereotactic Radiosurgery, in Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Immunoglobulin g1 (de-448-lysine), anti-(human tumor necrosis factor receptor tnfrsf18) (human-mus musculus …
Displaying drugs 926 - 950 of 1189 in total