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Displaying drugs 951 - 975 of 1033 in total

Iopofosine I-131

Iopofosine I-131 (NM-404 I-131) is under investigation in clinical trial NCT01495663 (Dose Escalation Study of I-131-CLR1404 in Subjects With Cancer That Does Not Respond to Treatment or Has Returned).
Investigational
Matched Synonyms: … 2-((HYDROXY((18-(4-(131I)IODOPHENYL)OCTADECYL)OXY)PHOSPHINYL)OXY)-N,N,NTRIMETHYLETHANAMINIUM INNER SALT ... Ethanaminium, 2-((hydroxy((18-(4-(iodo-131I)phenyl)octadecyl)oxy)phosphinyl)oxy)-N,N,N-trimethyl-, inner salt …

Tedizolid phosphate

Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Description: … ) and is generally more effective and more tolerable than [linezolid]. ... [L11232, A199086, A199050] Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist ... such as methicillin-resistant _Staphylococcus aureus_, vancomycin-resistant _Enterococcus faecium_, and …
Matched Products: … SIVEXTRO FILM-COATED TABLET 200MG …

Entacapone

Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration of...
Approved
Investigational
Matched Description: … and a decarboxylase inhibitor. ... When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased ... and more sustained plasma levodopa concentrations are reached as compared to the administration of levodopa …
Matched Mixtures name: … Carbidopa, Levodopa and Entacapone ... Carbidopa, Levodopa and Entacapone ... Carbidopa, Levodopa and Entacapone …
Matched Products: … Entacapone HEC 200 mg film-coated tablets …

Fenofibrate

Fenofibrate is a fibric acid derivative like clofibrate and gemfibrozil. Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.
Approved
Matched Description: … Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil]. …
Matched Mixtures name: … Cholib 145mg/20mg Film-Coated Tablet ... Cholib 145mg/40mg Film-Coated Tablet …
Matched Categories: … pravastatin and fenofibrate ... simvastatin and fenofibrate ... rosuvastatin and fenofibrate ... pravastatin, ezetimibe and fenofibrate …
Matched Products: … Fenofibrate film coated ... Lipanthyl Penta 145, film coated tablet ... CHOLIB FILM-COATED TABLET 145MG/20MG …

Magnesium phosphate

Experimental
Matched Synonyms: … Phosphoric acid, magnesium salt (2:3) …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …

BQ-788

Investigational
Matched Synonyms: … 6s)-2,6-dimethyl-1-piperidinyl)carbonyl)-4-methyl-l-leucyl-1-(methoxycarbonyl)-d-tryptophyl-, sodium salt …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Domperidone

A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Approved
Investigational
Vet approved
Matched Description: … It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … MOLAX-M FILM COATED TABLET ... DOMPERIDON - CT 10MG FILMT ... MOTILIUM 10 MG FILM TABLET, 21 ADET …

Pentoxifylline

Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched Description: … also has both anti-oxidant and anti-inflammatory properties. ... (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and ... Pharmaceuticals and APOTEX have been available since the late 1990s. …
Matched Products: … TRENTAL 400 FILM-COATED TABLET 400 mg ... TRENTAL CR 600 MG FILM KAPLI TABLET, 20 ADET ... TRENTILIN RETARD 600 MG FILM TABLET, 20 ADET …

Azacitidine

Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Description: … As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and ... inhibiting protein and DNA synthesis. ... [A1407] Due to its anti-neoplastic activity and its ability to inhibit methylation in replicating DNA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Onureg 200 mg Film Kaplı Tablet, 7 ADET ... Onureg 300 mg Film Kaplı Tablet, 7 ADET ... Onureg 200 mg Film Kaplı Tablet, 14 ADET …

Buprenorphine

Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Description: … opioids and who require larger and more frequent doses. ... Use of once-daily buprenorphine may benefit individuals who have developed tolerance to other potent ... Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist …
Matched Mixtures name: … Buprenorphine and Naloxone Sublingual Film ... Buprenorphine and Naloxone Sublingual Film ... Buprenorphine and Naloxone Sublingual Film …
Matched Products: … Bar-buprenorphine ... Buprenorphine Buccal Film …

Carvedilol

Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker.[L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension.[L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as...
Approved
Investigational
Matched Description: … , and the R(+) enantiomer is an alpha-1 adrenoceptor blocker. ... Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker ... [L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension …
Matched Categories: … Alpha and Beta Blocking Agents ... carvedilol and ivabradine ... Calcium-Regulating Hormones and Agents …
Matched Products: … Vacodil 25 Film-coated Tablet 25 mg ... Vacodil 6.25 Film-coated Tablet 6.25 mg ... Vacodil 12.5 Film-coated Tablet 12.5 mg …

Ticlopidine

Ticlopidine is an effective inhibitor of platelet aggregation. It is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot...
Approved
Matched Description: … Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin ... , and agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they are taking ... FDA label includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura …
Matched Categories: … Blood and Blood Forming Organs ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … TICLOPIDINA SALUS ... TICLID FILM COATED TABLET 250MG ... TICLOCARD 250 MG FILM KAPLI TABLET, 30 ADET …

Terbinafine

Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Products: … FILUT® TABLETAS ... FILUT NX® SOLUCION ... FILUT® TERBINAFINA AL 1% …

Yohimbine

A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Approved
Investigational
Vet approved
Matched International brands: … Baron-X …
Matched Description: … Yohimbine has been used as a mydriatic and in the treatment of impotence. …
Matched Categories: … Genito Urinary System and Sex Hormones …

Dipyridamole

A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Approved
Matched Description: … A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular …
Matched Mixtures name: … Aspirin and Dipyridamole ... Aspirin and Dipyridamole ... Aspirin and Dipyridamole Extended Release …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … DRİSENTİN 75 MG FILM KAPLI TABLET, 50 TABLET ... DRİSENTİN 75 MG FILM KAPLI TABLET, TABLET, 90 ADET …

Zopiclone

Zopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors. In addition to zopiclone's benzodiazepine pharmacological properties it also has some barbiturate-like properties.
Approved
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Zopiclone and prodrugs ... Sleep Initiation and Maintenance Disorders ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … ZOPICLON-HEXAL 7.5MG FILM ... IMOVANE 7.5 MG FİLM KAPLI TABLET, 5 ADET ... IMOVANE 7.5 MG FİLM KAPLI TABLET, 20 ADET …

Neoarsphenamine

Investigational
Withdrawn
Matched Synonyms: … Sulfoxylic acid, mono(((5-((3-amino-4-hydroxyphenyl)diarsenyl)-2-hydroxyphenyl)amino)methyl) ester, sodium salt …

Cefaclor

Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.
Approved
Matched Products: … CECLOR MR 375 MG.10 FILM TB. ... CECLOR MR 750 MG.10 FILM TB. ... SANOCEF 375 MG MR FILM TABLET, 10 TABLET …

Nicergoline

An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease.
Approved
Investigational
Matched Description: … An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. …
Matched Categories: … Ergot Alkaloids and Derivatives …
Matched Products: … SERMION 30 MG FILM TABLET, 30 ADET …

Sumatriptan

Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched Description: … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches ... [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available …
Matched Mixtures name: … Sumatriptan and Naproxen Sodium ... Sumatriptan Succinate and Naproxen Sodium ... Sumatriptan and Naproxen Sodium …
Matched Categories: … Genito Urinary System and Sex Hormones ... sumatriptan and naproxen ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … İMİGRAN 50 MG FILM KAPLI TABLET, 2 ADET ... İMİGRAN 50 MG FILM KAPLI TABLET, 6 ADET ... İMİGRAN 100 MG FILM KAPLI TABLET, 2 ADET …

Levocarnitine

Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Approved
Investigational
Matched Synonyms: … 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt …
Matched Description: … Constituent of striated muscle and liver. ... It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids and Derivatives …

Mycophenolic acid

Mycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties. . Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus)...
Approved
Investigational
Matched Description: … and antiviral properties. ... to optimize efficacy and minimize toxicity. ... [L42165] It was derived from _Penicillium stoloniferum_, and has also shown antibacterial, antifungal …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Mycophenolic Acid and Prodrugs …
Matched Products: … MICOSEF 500 MG FILM TABLET, 50 ADET ... CELLCEPT 500 MG FİLM KAPLI TABLET, 50 ADET ... CELLCEPT 500 MG FİLM KAPLI TABLET, 150 ADET …

Benazepril

Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor .
Approved
Investigational
Matched Description: … Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and …
Matched Mixtures name: … CİBADREX 5/6,25 MG FİLM TABLET, 28 ADET ... CİBADREX 10/12,5 MG FİLM TABLET, 28 ADET ... Benazepril Hydrochloride and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Diuretics ... ACE Inhibitors and Calcium Channel Blockers ... benazepril and diuretics ... benazepril and amlodipine …
Matched Products: … CİBACEN 10 MG FİLM KAPLI TABLET, 28 ADET …

Zolpidem

Zolpidem, also known as Ambien, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. It is aimed for use in patients with difficulties initiating sleep. This drug decreases the time to fall asleep (sleep latency), increases the...
Approved
Matched Description: … It is available in both immediate acting and extended release forms [FDA label], [F3802]. ... This drug decreases the time to fall asleep (sleep latency), increases the duration of sleep, and decreases ... according to the manufacturer’s instructions, with a low risk of drug withdrawal, drug dependence, and …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Zodenox Film Coated Tablets 10mg ... REMİN 10 MG FİLM TABLET, 14 ADET ... STILNOX 10MG FILM COATED TABLET …

Nimodipine

Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Compared to other calcium channel blocking...
Approved
Investigational
Matched Description: … of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … Nimodipine HEXAL® 30 mg Film-coated Tablet ... NIMOTOP 30 MG FILM KAPLI TABLET, 30 ADET …
Displaying drugs 951 - 975 of 1033 in total