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Displaying drugs 951 - 975 of 2474 in total
Experimental
Matched Synonyms: … Methyl ester nonanoic acid ... Pelargonic acid methyl ester …
Lonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK). In such way LND could impair energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and by some cytotoxic drugs.
Investigational
Matched Synonyms: … diclondazolic acid ... 1-(2,4-dichlorbenzyl)-indazole-3-carboxylic acid
Matched Iupac: … 1-[(2,4-dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid
Matched Description: … energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Investigational
Matched Synonyms: … Isonicotinic acid (2-(carboxymethoxy)benzylidene)hydrazide ... Isonicotinic acid (o-(carboxymethoxy)benzylidene)hydrazide …
Matched Iupac: … 2-{2-[(E)-{[(pyridin-4-yl)formamido]imino}methyl]phenoxy}acetic acid
Matched Categories: … Acids, Heterocyclic ... Isonicotinic Acids
Taurine, whose chemical name is 2-aminoethanesulfonic acid, is one of the most abundant amino acids in several organs. It plays important role in essential biological processes. This conditional amino acid can be either be manufactured by the body or obtained in the diet mainly by the consumption of fish and...
Approved
Nutraceutical
Matched Synonyms: … Aminoethylsulfonic acid
Matched Iupac: … 2-aminoethane-1-sulfonic acid
Matched Description: … mainly by the consumption of fish and meat. ... [L1058] The supplements containing taurine were FDA approved by 1984 and they are hypertonic injections ... Taurine, whose chemical name is 2-aminoethanesulfonic acid, is one of the most abundant amino acids in …
Matched Mixtures name: … Premasol - sulfite-free (Amino Acid) ... Premasol - sulfite-free (Amino Acid) ... PRIMENE 10% AMINO ACID INTRAVENOUS INFUSION …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sulfur Acids ... Sulfonic Acids ... Sulfur Compounds ... Amino Acids
Experimental
Matched Synonyms: … 4-Guaiacolsulfonic acid
Matched Iupac: … 4-hydroxy-3-methoxybenzene-1-sulfonic acid
Dimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis.[A253942,L43752] The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood. It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor...
Approved
Investigational
Matched Synonyms: … Fumaric acid, dimethyl ester ... (E)-But-2-enedioic acid dimethyl ester ... trans-Butenedioic acid dimethyl ester …
Matched Description: … agent for multiple sclerosis approved by the FDA, following [fingolimod] and [teriflunomide]. ... [L43752] Dimethyl fumarate is marketed under the brand name Tecfidera, and it was the third oral disease-modifying …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids
Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so...
Approved
Matched International brands: … Acil
Matched Synonyms: … Benzoic acid, benzyl ester ... Benzoic acid phenylmethylester ... Benzoic acid, phenylmethyl ester …
Matched Description: … It is also used to treat lice infestation of the head and body. ... Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. ... It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides, Insecticides and Repellents ... Acids, Carbocyclic ... Carboxylic Acids
A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Approved
Investigational
Vet approved
Matched Synonyms: … Yohimbic acid methyl ester ... 17α-hydroxyyohimban-16α-carboxylic acid methyl ester ... (16α,17α)-17-hydroxyyohimban-16-carboxylic acid methyl ester …
Matched Description: … Yohimbine has been used as a mydriatic and in the treatment of impotence. …
Matched Categories: … Genito Urinary System and Sex Hormones …
Ingavirin has been used in trials studying the treatment of Influenza and Common Cold.
Investigational
Matched Synonyms: … IMIDAZOLYL ETHANAMIDE PENTANDIOIC ACID
Matched Iupac: … 4-{[2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid
Matched Description: … Ingavirin has been used in trials studying the treatment of Influenza and Common Cold. …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Enoxolone (glycyrrhetic acid) has been investigated for the basic science of Apparent Mineralocorticoid Excess (AME).
Investigational
Matched Synonyms: … Glycyrrhetic Acid
Matched Iupac: … 9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid
Matched Description: … Enoxolone (glycyrrhetic acid) has been investigated for the basic science of Apparent Mineralocorticoid …
Matched Salts name: … Potassium glycyrrhetinate …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …
ADU-S100 (MIW815) is a synthetic cyclic dinucleotide (CDN) agonist (activator) of Stimulator of Interferon Genes (STING), a receptor crucial to activate the innate (endogenous) immune system. ADU-S100 (MIW815) activates all known human and mouse STINGs, and effectively induces the expression of cytokines and chemokines, leading to a robust and durable...
Investigational
Matched Synonyms: … ADU-S100 free acid
Matched Description: … ADU-S100 (MIW815) activates all known human and mouse STINGs, and effectively induces the expression ... of cytokines and chemokines, leading to a robust and durable antigen-specific T-cell mediated immune …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Poly(lactic acid) is under investigation in clinical trial NCT00126308 (Facial Lipoatrophy Trial: Immediate Versus Deferred Injections of Poly-L-Lactic Acid for HIV Facial Lipoatrophy).
Investigational
Matched Synonyms: … POLY-L-LACTIC ACID
Matched Name: … Poly(lactic acid) …
Matched Description: … Versus Deferred Injections of Poly-L-Lactic Acid for HIV Facial Lipoatrophy). ... Poly(lactic acid) is under investigation in clinical trial NCT00126308 (Facial Lipoatrophy Trial: Immediate …
Investigational
Matched Synonyms: … Ketoisostevic acid
Matched Iupac: … 4S,5R,9S,10R,13S)-5,9,13-trimethyl-14-oxotetracyclo[11.2.1.0^{1,10}.0^{4,9}]hexadecane-5-carboxylic acid
Experimental
Matched Synonyms: … Glutamic acid alpha-amide ... L-Glutamic acid alpha-amide …
Matched Iupac: … (4S)-4-amino-4-carbamoylbutanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino ... Amino Acids, Neutral …
Experimental
Matched Synonyms: … (3R)-3-methyl-L-glutamic acid ... (2S,3R)-2-azanyl-3-methyl-pentanedioic acid
Matched Name: … 3-Methylglutamic acid
Matched Iupac: … (2S,3R)-2-amino-3-methylpentanedioic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic ... Excitatory Amino Acids
Investigational
Matched Synonyms: … 3a,6b,7b,12a-(OH)4-5b-cholanic acid ... (3α,5β,6β,7β,12α)-3,6,7,12-Tetrahydroxycholan-24-oic acid ... 3alpha,6beta,7beta,12alpha-Tetrahydroxy-5beta-cholanoic acid
Matched Name: … 3alpha,6beta,7beta,12alpha-tetrahydroxy-5beta-cholan-24-oic acid
Matched Iupac: … 4-{4,5,7,11-tetrahydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl}pentanoic acid
An essential amino acid that is physiologically active in the L-form.
Investigational
Nutraceutical
Matched Synonyms: … (2S)-2-amino-5-guanidinopentanoic acid ... (S)-2-Amino-5-guanidinovaleric acid ... (S)-2-amino-5-guanidinopentanoic acid
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid
Matched Description: … An essential amino acid that is physiologically active in the L-form. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... arginine and lysine ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Amino Acids
An important regulator of gene expression during growth and development, and in neoplasms. Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic. It is used in the treatment of psoriasis; acne vulgaris;...
Approved
Investigational
Matched Synonyms: … 9-cis-retinoic acid ... 9(Z)-Retinoic acid ... (7E,9Z,11E,13E)-retinoic acid
Matched Iupac: … (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
Matched Description: … Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth ... An important regulator of gene expression during growth and development, and in neoplasms. ... ; and embryonic development. …
Matched Categories: … Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Experimental
Matched Synonyms: … 2-Amino-6-hydroxycaproic acid ... alpha-Amino-epsilon-hydroxycaproic acid
Matched Iupac: … (2S)-2-amino-6-hydroxyhexanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Eprodisate slows the decline of renal function in AA amyloidosis.
Investigational
Matched Synonyms: … 1,3-propanedisulfonic acid ... Propane-1,3-disulfonic acid
Matched Iupac: … propane-1,3-disulfonic acid
Matched Categories: … Sulfur Acids ... Sulfur Compounds ... Acids ... Acids, Noncarboxylic …
Monoctanoin is used to dissolve cholesterol gallstones.
Experimental
Matched Synonyms: … Caprylic acid α-monoglyceride ... Octanoic acid 1-monoglyceride …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids
TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABAC receptors (also known as GABA-ρ or GABAA-ρ receptors). GABAC receptors are found primarily in the retina, although they may be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and the gut.[A245308,A245313] TPMPA is used as a pharmacological...
Experimental
Matched Synonyms: … (1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid ... P-Methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)phosphinic acid ... Phosphinic acid, P-methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)- …
Matched Iupac: … methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid
Matched Description: … be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and ... TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABA
A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Approved
Nutraceutical
Matched Synonyms: … L-a-Amino-g-methylthiobutyric acid ... (S)-2-amino-4-(methylthio)butanoic acid ... (2S)-2-amino-4-(methylsulfanyl)butanoic acid
Matched Iupac: … (2S)-2-amino-4-(methylsulfanyl)butanoic acid
Matched Description: … A sulfur containing essential amino acid that is important in many body functions. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Men's Biomultiple Vitamin and Mineral Supplement …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Sulfur ... Sulfur Compounds ... Amino Acids ... Amino Acids, Neutral …
Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and the central nervous system.
Nutraceutical
Matched Synonyms: … (2S)-2-aminopropanoic acid ... (S)-2-aminopropanoic acid ... L-2-Aminopropionic acid
Matched Iupac: … (2S)-2-aminopropanoic acid
Matched Description: … It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue ... , brain, and the central nervous system. ... Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Proteinogenic Amino Acids
Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Synonyms: … Acid maltase ... Acid-alpha glucosidase ... Human acid precursor alpha-glucosidase, recombinant …
Matched Description: … Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the ... It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients. ... Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Displaying drugs 951 - 975 of 2474 in total