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Displaying drugs 951 - 975 of 1347 in total
Axicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. The drug has a unique mechanism of action, as it utilizes the patient's own T cells, which play a central role in immune response to cancer. Once T-cells are collected from the patient, they are genetically engineered to express...
Approved
Matched Description: … ] Once T-cells are collected from the patient, they are genetically engineered to express anti-CD19 CARs ... Axicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. ... researchers at the National Cancer Institute (NCI), who demonstrated that T cells expressing an anti-CD19 CAR
Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration of...
Approved
Investigational
Matched Description: … ., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to …
Matched Mixtures name: … LEV/CAR/EN AL100/25/200 ... LEV/CAR/EN AL200/50/200 ... LEV/CAR/EN AL50/12.5/200 …
Levodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier[Label]. Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent...
Approved
Matched Description: … the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa ... The first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product …
Matched Mixtures name: … LEV/CAR/EN AL100/25/200 ... LEV/CAR/EN AL200/50/200 ... LEV/CAR/EN AL50/12.5/200 …
Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension. Other members of this drug class include Prazosin, Terazosin, Tamsulosin, and Alfuzosin. Because of its long-lasting effects, doxazosin can be administered once a day. It is marketed by Pfizer and was initially approved...
Approved
Matched International brands: … Cardular ... Cardenalin ... Carduran
Matched Iupac: … 2-[4-(2,3-dihydro-1,4-benzodioxine-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine …
Matched Mixtures name: … Cardura-1,2,and 4 ... Cardura-1,2,and 4 ... Cardura-1,2,and 4 …
Matched Categories: … Cardiovascular Agents ... Cardiovascular System …
Matched Products: … CARDURAN® XL 4 MG ... CARDURAN® 4 MG TABLETAS ... CARDULAR PP 4MG …
Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the...
Approved
Matched Salts name: … Guaiacol carbonate
Moxisylyte, denominated as thymoxamine in the UK, is a specific and orally active α1-adrenergic antagonist. According to the WHO, moxisylyte is approved since 1987 and in the same year, it acquired the denomination of orphan product by the FDA. This drug was developed by the Japanese company Fujirebio and also...
Approved
Investigational
Matched International brands: … Carlytene
Matched Categories: … Cardiovascular Agents ... Cardiovascular System …
An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex. [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and...
Approved
Withdrawn
Matched International brands: … Cardioxane
Matched Description: … Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity ... drug for use in the prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy
Matched Categories: … Cardiotonic Agents ... Cardiovascular Agents …
Matched Products: … Cardioxane ... CARDIOXANE® ... CARDIOXANE
Clove allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Caryophylli flos ... Eugenia caryophyllata ... Eugenia caryophyllata bud …
Camponotus pennsylvanicus allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Black carpenter ant ... Black carpenter ant whole …
Matched Products: … Black Carpenter Ant …
Tilletia caries allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Uredo caries ... Tilletia caries ... Tilletia caries whole …
Matched Name: … Tilletia caries
Matched Description: … Tilletia caries allergenic extract is used in allergenic testing. …
Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.
Approved
Matched Synonyms: … (8β)-N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide ... (8R)-6-allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide ... 1-((6-allylergolin-8β-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea …
Matched Iupac: … )-6-(prop-2-en-1-yl)-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraene-4-carbonyl
A commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Approved
Vet approved
Matched International brands: … Cardiografin
Matched Categories: … Carbohydrates ... Acids, Carbocyclic ... Carboxylic Acids …
An antibiotic derived from penicillin similar to carbenicillin in action.
Approved
Investigational
Vet approved
Matched Synonyms: … ]heptane-2-carboxylic acid ... α-carboxy-3-thienylmethylpenicillin ... (2S,5R,6R)-6-{[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Matched Iupac: … ]heptane-2-carboxylic acid ... (2S,5R,6R)-6-[(2R)-2-carboxy-2-(thiophen-3-yl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Matched Description: … An antibiotic derived from penicillin similar to carbenicillin in action. …
Safflower (Carthamus tinctorius L) is a herbaceous plant in the Asteraceae family. Extracted from the seeds of safflowers, safflower oil is a rich source of various saturated fatty acids, monounsaturated fatty acid (oleic acid) or essential n-6 polyunsaturated fatty acid (PUFA) linoleic acid [A32677, A32679], depending on the flower type....
Approved
Investigational
Matched Synonyms: … Carthamus tinctorius seed oil …
Matched Mixtures name: … Carthaphy Cap …
Approved
Experimental
Matched Synonyms: … Iron carbonate, precipitated ... Ferric carbonate, ferric hydroxide, ferrous hydroxide (variable mixture) …
A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
Approved
Vet approved
Matched International brands: … Caropram
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched Synonyms: … 3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one ... 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid ... 1-ethyl-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one-3-carboxylic acid …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Ceftibuten is a third-generation cephalosporin antibiotic that is orally-administered. It is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
Approved
Investigational
Matched Synonyms: … 2-ene-2-carboxylic acid ... (+)-(6R,7R)-7-((Z)-2-(2-amino-4-thiazolyl)-4-carboxycrotonamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct- …
Matched Iupac: … oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enamido]-8-oxo-5-thia-1-azabicyclo[4.2.0] …
A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.
Approved
Matched Synonyms: … Crystal violet carbocation ... Gentian violet carbocation
Azlocillin is a semisynthetic ampicillin-derived acylureido penicillin.
Approved
Matched Synonyms: … }-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-3,3-dimethyl-7-oxo-6-{[(2R)-2-{[(2-oxoimidazolidin-1-yl)carbonyl]amino}-2-phenylacetyl]amino …
Matched Iupac: … -1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetamido]-4-thia …
A vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
Approved
Investigational
Matched International brands: … Carvasin
Matched Categories: … Carbohydrates ... Cardiac Therapy ... Cardiovascular Agents ... Cardiovascular System ... Vasodilators Used in Cardiac Diseases …
Matched Products: … CARVASIN ... CARDIOKET 5 MG TABLET, 40 ADET ... CARDIOKET 5 MG TABLET, 500 ADET …
Tetrakis (2-methoxyisobutylisocyanide) copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for assessing myocardial perfusion.
Approved
Matched Synonyms: … Cardio-spect …
Matched Description: … Tetrakis (2-methoxyisobutylisocyanide) copper (I) tetrafluoroborate is a component of Cardiolite, a technetium …
Matched Products: … Cardiolite ... CardioTOP 1 mg Kit für ein radioaktives Arzneimittel ... CARDIO-SPECT RADYOFARMASÖTIK HAZIRLAMA KITI, 6 ADET …
An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
Approved
Investigational
Vet approved
Matched International brands: … Caricide ... Carbilazine
Matched Iupac: … N,N-diethyl-4-methylpiperazine-1-carboxamide
Matched Categories: … Carbamates ... Carboxylic Acids …
Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Synonyms: … (Z)-(S)-6-carboxy-6-[(S)-2,2-dimethylcyclopropanecarboxamido]hex-5-enyl-L-cysteine ... (L)-7-(2-Amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid ... (Z)-7-((R)-2-Amino-2-carboxy-ethylsulfanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2- …
Matched Iupac: … (2Z)-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoic …
Displaying drugs 951 - 975 of 1347 in total