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Displaying drugs 76 - 100 of 12154 in total
Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Approved
Withdrawn
Matched Synonyms: … 1-Phenyl-2-(1',1'-diphenylpropyl-3'-amino)propane ... N-(1-Methyl-2-phenylethyl)-gamma-phenylbenzenepropanamine …
Matched Iupac: … (3,3-diphenylpropyl)(1-phenylpropan-2-yl)amine …
Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of...
Approved
Matched Synonyms: … 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine ... 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine …
Matched Iupac: … 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine …
Matched Products: … IMURAN 50 MG FLAKON, 1 ADET …
A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Approved
Matched Synonyms: … 1-Methyl-5-p-toluoylpyrrole-2-acetic acid ... 5-(p-Toluoyl)-1-methylpyrrole-2-acetic acid ... 1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid …
Matched Iupac: … 2-[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP...
Approved
Matched Synonyms: … 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-ol …
Matched Iupac: … (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol …
Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist (IL-1Ra) composed of 153 amino acid residues. Unlike native human IL-1Ra, anakinra has an additional methionine residue at the amino terminus. This drug binds to the IL-1 receptor, competing with and inhibiting the activity of IL-1 alpha and beta. Anakinra is...
Approved
Investigational
Matched Synonyms: … Interleukin-1 receptor antagonist anakinra …
Matched Description: … Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist (IL-1Ra) composed of 153 amino ... This drug binds to the IL-1 receptor, competing with and inhibiting the activity of IL-1 alpha and beta ... treatment of neonatal-onset multisystem inflammatory disease (NOMID) and deficiency of interleukin-1
Matched Categories: … Interleukin-1 Receptor Antagonist …
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one ... NRL-1
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Mixtures name: … Gabavale-5
Matched Products: … NOZEPAV 5 ... Meval 5 ... DİAKSİ 5 MG/2.5 ML REKTAL ÇÖZELTİ, 5 ADET …
Edaravone is a free radical scavenger and neuroprotective agent with antioxidant properties. It has three tautomers. Edaravone works to scavenge reactive oxygen species, which have been implicated in neurological disorders, such as amyotrophic lateral sclerosis (ALS) and cerebral ischemia.[A19140,L44007,A254257] The intravenous formulation of edaravone was first approved in Japan in...
Approved
Investigational
Matched Synonyms: … 3-methyl-1-phenyl-5-pyrazolone ... 3-methyl-1-phenylpyrazol-5-one ... 1-phenyl-3-methyl-5-oxo-2-pyrazoline …
Matched Iupac: … 3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cefamandole is also known as cephamandole. It is a parenterally administered broad-spectrum cephalosporin antibiotic. It is generally formulated as a formate ester, cefamandole nafate. It is no longer marketed in the United States.
Approved
Experimental
Matched Synonyms: … (6R,7R)-7-(R)-Mandelamido-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0 ... -5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo …
Matched Iupac: … 8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2R)-2-hydroxy-2-phenylacetamido]-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}- …
A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist.[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by...
Approved
Investigational
Matched Synonyms: … 2(3H)-FURANONE, 3-ETHYLDIHYDRO-4-((1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-, (3S-CIS)- …
Matched Iupac: … (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one …
Matched Salts cas: … 148-72-1
Matched Mixtures name: … E-pilo-1 Oph Soln ... E-pilo 1 Ophthalmic Solution …
Matched Products: … -carpine 1% ... PILOMANN 1% ... Pilocarpine 1% …
Prazosin is a drug used to treat hypertension. Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988. It belongs to the class of drugs known as alpha-1 antagonists. Recently, many studies have evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress...
Approved
Matched Synonyms: … 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline ... 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine …
Matched Iupac: … 2-[4-(furan-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine …
Matched Description: … [L5828] It belongs to the class of drugs known as alpha-1 antagonists. …
Matched Categories: … Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Prazosin-5 Tab ... APO-PRAZO TABLET 5 mg ... NOPRES 5 MG TABLET, 30 ADET …
Docosanol is a drug used for topical treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters). A saturated 22-carbon aliphatic alcohol, docosanol exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol inhibits fusion between the plasma membrane and the herpes...
Approved
Investigational
Matched Synonyms: … 1-Docosanol ... Docosan-1-ol …
Matched Iupac: … docosan-1-ol …
Menthyl salicylate is an ester of menthol and salicylic acid . This product is used to treat minor aches and pains of the muscles/joints (e.g., arthritis, backache, sprains) .
Approved
Matched Synonyms: … 1-Menthyl salicylate …
Matched Iupac: … (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl 2-hydroxybenzoate …
Perfluorohexyloctane is a semifluorinated alkane that contains six perfluorinated carbon atoms and eight hydrogenated carbon atoms. It is an inert, slightly amphiphilic compound. Because it is a completely non-aqueous liquid, microbial growth is not possible; therefore, its drug products do not need to be combined with any preservative.[A259746, A259751] Perfluorohexyloctane...
Approved
Matched Synonyms: … 1-(perfluorohexyl)octane …
Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. Gatifloxacin is available as...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid ... 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid …
Matched Iupac: … 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha sterol demethylase...
Approved
Matched Synonyms: … (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol ... (αR,βS)-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol …
Matched Iupac: … (3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … İNFÜZYONLUK ÇÖZELTİ İÇİN TOZ, 1 ADET ... VFEND IV 200 MG İNFÜZYON ÇÖZELTİSİ İÇİN TOZ, 1 ADET ... VORIGEN 200 MG IV INFÜZYON ÇÖZELTISI IÇIN TOZ,1 ADET …
A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Approved
Investigational
Matched Synonyms: … trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine ... 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine …
Matched Iupac: … 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine …
Matched Salts cas: … 440-17-5
Matched Mixtures name: … Stelabid No 1
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … STILIZAN AMPUL 1 MG, 5 ADET ... ไตรโอซิน 1 ... ไตรโอซิน 5
Cefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically used in the treatment of female gynecologic and obstetric infections. It is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria.
Approved
Matched Synonyms: … )-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure ... ]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-((Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-((1-methyl-1H-5-tetraazolylthio)methyl …
Matched Iupac: … -5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-{[(1-methyl-1H-1,2,3,4-tetrazol …
Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.
Approved
Matched Synonyms: … 1-((6-allylergolin-8β-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea ... 1-[(6-allylergoline-8β-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea ... 1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'β-carbonyl)urea …
Matched Iupac: … 1-[3-(dimethylamino)propyl]-3-ethyl-1-[(2R,4R,7R)-6-(prop-2-en-1-yl)-6,11-diazatetracyclo[7.6.1.0^{2,7 ... }.0^{12,16}]hexadeca-1(16),9,12,14-tetraene-4-carbonyl]urea …
Matched Categories: … Serotonin 5-HT1 Receptor Agonists ... Serotonin 5-HT2 Receptor Agonists …
Matched Products: … Cabaseril 1 mg - Tabletten ... CABASER 1 MG TABLET, 20 ADET …
Miconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well. It is widely used to treat mucosal yeast infections, including both oral and vaginal infections; although intravenous miconazole is no longer available, a wide variety of suppositories, creams, gels, and tablet-based products are available.[L14021, L14024, L14027,...
Approved
Investigational
Vet approved
Matched Synonyms: … 1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole ... 1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole …
Matched Iupac: … 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole …
Matched Mixtures name: … Miconazole 1 ... Miconazole 1 ... Miconazole 1
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … MICATIN (R) 7 VAGINAL SUPPOSITORIES ... Monistat 1 Vaginal Ovule ... MIKO-PENOTRAN 1200 MG OVUL, 1 ADET …
Cetyl alcohol, also known as 1-hexadecanol or n-hexadecyl alcohol, is a 16-C fatty alcohol with the chemical formula CH3(CH2)15OH. It can be produced from the reduction of palmitic acid. Cetyl alcohol is present in a waxy white powder or flake form at room temperature, and is insoluble in water and...
Approved
Matched Synonyms: … hexadecan-1-ol …
Matched Iupac: … hexadecan-1-ol …
Matched Description: … Cetyl alcohol, also known as 1-hexadecanol or n-hexadecyl alcohol, is a 16-C fatty alcohol with the chemical …
Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule...
Approved
Matched Synonyms: … 2-chloro-5-(1-hydroxy-3-oxo-1-isoindolinyl)benzenesulfonamide ... 2-chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)benzenesulfonamide ... 1-keto-3-(3'-sulfamyl-4'-chlorophenyl)-3-hydroxyisoindoline …
Matched Iupac: … 2-chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzene-1-sulfonamide …
Adrenergic beta-agonist used to control premature labor.
Approved
Investigational
Matched Synonyms: … p-Hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)benzyl alcohol …
Matched Iupac: … 4-[(1S,2R)-1-hydroxy-2-{[2-(4-hydroxyphenyl)ethyl]amino}propyl]phenol …
Matched Products: … PRE-PAR 50 MG/5 ML IM/IV ÇÖZELTİ İÇEREN AMPUL, 1 AMPUL …
Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as a GLP-1 receptor agonist.[Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine for lysine at position 34. Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid...
Approved
Matched Synonyms: … Arg34Lys26-(N-ε-(γ-Glu(N-α-hexadecanoyl)))-GLP-1[7-37] ... N²⁶-(hexadecanoyl-gamma-glutamyle)-[34-arginine]GLP-1-(7-37)-peptide ... N²⁶-(N-Hexadecanoyl-L-gamma-glutamyl)-[34-L-arginine]glucagon-like peptide 1-(7-37)-peptide …
Matched Description: … a GLP-1 receptor agonist. ... Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as ... [Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine …
Matched Mixtures name: … XULTOPHY 100U/ML+3.6MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET ... XULTOPHY 100U/ML+3.6MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 ADET …
Matched Categories: … Glucagon-like peptide-1 (GLP-1) analogues ... GLP-1 Agonists ... Glucagon-Like Peptide 1
Matched Products: … SAXENDA 6 MG/ML ENJEKSIYONLUK ÇÖZELTI IÇEREN KULLANIMA HAZIR KALEM, 1 ENJEKTÖR ... SAXENDA 6 MG/ML ENJEKSIYONLUK ÇÖZELTI IÇEREN KULLANIMA HAZIR KALEM, 5 ENJEKTÖR ... VICTOZA 6 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 ADET …
Diphenidol is an antiemetic agent used in the treatment of vomiting and vertigo. Diphenidol overdose may result in serious toxicity in children.
Approved
Investigational
Withdrawn
Matched Synonyms: … alpha,alpha-Diphenyl-1-piperidinebutanol ... Diphenyl(3-(1-piperidyl)propyl)carbinol …
Matched Iupac: … 1,1-diphenyl-4-(piperidin-1-yl)butan-1-ol …
Matched Salts cas: … 3254-89-5
Matched Categories: … Heterocyclic Compounds, 1-Ring …
An alkylating agent of value against both hematologic malignancies and solid tumors.
Approved
Investigational
Matched Synonyms: … 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea ... 1-(2-chloroethyl)-3-cyclohexylnitrosourea …
Matched Iupac: … 3-(2-chloroethyl)-1-cyclohexyl-3-nitrosourea …
Displaying drugs 76 - 100 of 12154 in total