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Displaying drugs 76 - 100 of 8829 in total
Deferiprone
Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired....
Approved
Matched Synonyms: … 1,2-Dimethyl-3-hydroxypyrid-4-one ... 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone …
Matched Iupac: … 3-hydroxy-1,2-dimethyl-1,4-dihydropyridin-4-one …
Matched Iupac: … 3-hydroxy-1,2-dimethyl-1,4-dihydropyridin-4-one …
Norethisterone
Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. It is further classified as a second-generation progestin, along with levonorgestrel and its derivatives, and is the active form of several other progestins including norethynodrel and lynestrenol. Norethisterone mimics the actions of endogenous...
Approved
Matched Synonyms: … 17-α-ethynyl-4-estren-17-ol-3-one ... 17α-ethynyl-4-estren-17-ol-3-one ... 17α-ethinylestra-4-en-17β-ol-3-one …
Matched Mixtures name: … Ovcon 50 ... Ovcon 50 ... Estalis 140/50 Mcg …
Matched Mixtures name: … Ovcon 50 ... Ovcon 50 ... Estalis 140/50 Mcg …
Practolol
A beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.
Approved
Matched Synonyms: … 1-(4-acetamidophenoxy)-3-isopropylamino-2-propanol ... 4'-(2-hydroxy-3-(isopropylamino)propoxy)acetanilide ... N-(4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)acetamide …
Matched Iupac: … N-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide …
Matched Iupac: … N-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide …
Oxacillin
An antibiotic similar to flucloxacillin used in resistant staphylococci infections.
Approved
Investigational
Matched Synonyms: … (2S,5R,6R)-3,3-dimethyl-6-{[(5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo ... 5-methyl-3-phenyl-4-isoxazolyl-penicillin ... (5-methyl-3-phenyl-4-isoxazolyl)penicillin …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane …
Bosentan
Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Synonyms: … 4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide ... p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide …
Matched Iupac: … 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl]benzene-1-sulfonamide …
Matched Iupac: … 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl]benzene-1-sulfonamide …
Sonidegib
Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer agent by Novartis. It was FDA approved in 2015 for the treatment of basal cell carcinoma.
Approved
Investigational
Matched Synonyms: … N-[6-(cis-2,6-dimethylmorpholin-4-yl)pyridin-3-yl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide …
Matched Iupac: … N-{6-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pyridin-3-yl}-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl] …
Matched Iupac: … N-{6-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pyridin-3-yl}-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl] …
Zuclopenthixol
Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent. Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. Major brands of zuclopenthixol are Cisordinol, Acuphase, and Clopixol. This drug is a liquid. This compound...
Approved
Investigational
Matched Synonyms: … (Z)-4-(3-(2-Chlorothioxanthen-9-ylidene)propyl)-1-piperazineethanol …
Matched Iupac: … 2-(4-{3-[(9Z)-2-chloro-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethan-1-ol …
Matched Products: … CLOPIXOL 2 MG FILM TABLET, 50 ADET ... Cisordinol Acutard 50 mg - Ampullen ... CLOPIXOL ACUPHASE 50 MG/ML IM ENJ. SOLUSYON, 1 ML …
Matched Iupac: … 2-(4-{3-[(9Z)-2-chloro-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethan-1-ol …
Matched Products: … CLOPIXOL 2 MG FILM TABLET, 50 ADET ... Cisordinol Acutard 50 mg - Ampullen ... CLOPIXOL ACUPHASE 50 MG/ML IM ENJ. SOLUSYON, 1 ML …
Vanillyl butyl ether
Vanillyl butyl ether is an ether of monohydroxybenzoic acid. It is added to food products as a flavoring agent. It is also present in cosmetics and personal care products as a fragrance ingredient, oral care agent, hair conditioning agent, and warming or cooling agent.
Approved
Matched Synonyms: … 4-(Butoxymethyl)-2-methoxyphenol …
Matched Iupac: … 4-(butoxymethyl)-2-methoxyphenol …
Matched Iupac: … 4-(butoxymethyl)-2-methoxyphenol …
Diosmin
Chronic venous insufficiency is a common condition the western population. Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease. Diosmin is a bioflavonoid isolated from various plants or synthesized from hesperidin. It is used for the improvement of capillary fragility or...
Approved
Investigational
Matched Synonyms: … 3',5,7-trihydroxy-4'-methoxyflavone-7-rutinoside ... 3',5,7-trihydroxy-4'-methoxyflavone 7-rhamnoglucoside …
Matched Iupac: … -trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one ... 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5 …
Matched Mixtures name: … DIOKERN 450 MG/50 MG FILM KAPLI TABLET,30 ADET ... DIOKERN 450 MG/50 MG FILM KAPLI TABLET,60 ADET ... VARIDOS 450 MG/50 MG FILM KAPLI TABLET, 30 ADET …
Matched Iupac: … -trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one ... 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5 …
Matched Mixtures name: … DIOKERN 450 MG/50 MG FILM KAPLI TABLET,30 ADET ... DIOKERN 450 MG/50 MG FILM KAPLI TABLET,60 ADET ... VARIDOS 450 MG/50 MG FILM KAPLI TABLET, 30 ADET …
Deslanoside
Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata.
Approved
Matched Synonyms: … (3β,5β,12β)-3-{[β-D-glucopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl ... 3-[(O-β-D-glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl ... -(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy}-12,14-dihydroxycard-20(22)-enolide …
Matched Iupac: … 4-[(1R,3aS,3bR,5aR,7S,9aS,9bS,11R,11aS)-3a,11-dihydroxy-7-{[(2R,4S,5S,6R)-4-hydroxy-5-{[(2S,4S,5S,6R) ... -4-hydroxy-5-{[(2S,4S,5S,6R)-4-hydroxy-6-methyl-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl …
Matched Iupac: … 4-[(1R,3aS,3bR,5aR,7S,9aS,9bS,11R,11aS)-3a,11-dihydroxy-7-{[(2R,4S,5S,6R)-4-hydroxy-5-{[(2S,4S,5S,6R) ... -4-hydroxy-5-{[(2S,4S,5S,6R)-4-hydroxy-6-methyl-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl …
Sotorasib
Sotorasib, also known as AMG-510, is an acrylamide-derived KRAS inhibitor developed by Amgen.[A187547,A187556] It is indicated in the treatment of adult patients with KRAS G12C mutant non-small cell lung cancer. This mutation makes up >50% of all KRAS mutations. Mutant KRAS discovered in 1982 but was not considered a druggable...
Approved
Investigational
Matched Synonyms: … 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-(1M)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[(2S)-2- methyl ... -4-(prop-2-enoyl)piperazin-1-yl]pyrido[2,3-d]pyrimidin-2(1H)-one …
Matched Iupac: … 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[(2S)-2-methyl-4-(prop …
Matched Description: … [L34288] This mutation makes up >50% of all KRAS mutations. …
Matched Iupac: … 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[(2S)-2-methyl-4-(prop …
Matched Description: … [L34288] This mutation makes up >50% of all KRAS mutations. …
Dapagliflozin
Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron...
Approved
Matched Synonyms: … (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol …
Matched Iupac: … (2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(hydroxymethyl)oxane-3,4,5-triol …
Matched Iupac: … (2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(hydroxymethyl)oxane-3,4,5-triol …
Pyrimethamine
One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Approved
Investigational
Vet approved
Matched Synonyms: … 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine ... 5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine ... 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine …
Matched Iupac: … 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine …
Matched Iupac: … 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine …
Nalidixic acid
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched Synonyms: … 1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure ... 3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one ... 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Categories: … 4-Quinolones …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Categories: … 4-Quinolones …
Voriconazole
Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha sterol demethylase...
Approved
Matched Synonyms: … (αR,βS)-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol ... (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol …
Matched Iupac: … (3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol …
Matched Products: … VORITROP 50 FILM COATED TABLET 50 MG ... VORITROP 50 (Voriconazole Tablets 50 mg) ... NEUCLER® 50 MG …
Matched Iupac: … (3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol …
Matched Products: … VORITROP 50 FILM COATED TABLET 50 MG ... VORITROP 50 (Voriconazole Tablets 50 mg) ... NEUCLER® 50 MG …
Lenalidomide
Lenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. It is a 4-amino-glutamyl analogue of thalidomide and like thalidomide, lenalidomide exists as a racemic mixture of the active S(-) and R(+) forms. However, lenalidomide is much safer and potent than thalidomide, with...
Approved
Matched Synonyms: … 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline ... 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione …
Matched Iupac: … 3-(4-amino-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione …
Matched Description: … [A228553] It is a 4-amino-glutamyl analogue of [thalidomide] [A228543] and like thalidomide, lenalidomide …
Matched Iupac: … 3-(4-amino-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione …
Matched Description: … [A228553] It is a 4-amino-glutamyl analogue of [thalidomide] [A228543] and like thalidomide, lenalidomide …
Medrysone
Medrysone is a corticosteroid used in ophthalmology.
Approved
Matched Synonyms: … 11beta-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione …
Natalizumab
Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULFIDE WITH HUMAN-MOUSE ... IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULPHIDE WITH HUMAN-MOUSE …
Sulfapyridine
Antibacterial, potentially toxic, and previously used to treat certain skin diseases. No longer prescribed.
Approved
Matched Synonyms: … 4-(2-Pyridinylsulfonyl)aniline ... 4-[(2-Pyridylamino)sulfonyl]aniline ... 4-Amino-N,2-pyridinylbenzenesulfonamide …
Matched Iupac: … 4-amino-N-(pyridin-2-yl)benzene-1-sulfonamide …
Matched Iupac: … 4-amino-N-(pyridin-2-yl)benzene-1-sulfonamide …
Irinotecan
Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Synonyms: … (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin ... -9-yl 4-(2-(5-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-hydroxy-4H-1,2,4-triazol-4-yl)-1H-indol-1-yl)ethyl …
Penciclovir
Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
Approved
Matched Synonyms: … 9-(4-hydroxy-3-(hydroxymethyl)butyl)guanine ... 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine ... 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine …
Matched Iupac: … 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6,9-dihydro-3H-purin-6-one …
Matched Iupac: … 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6,9-dihydro-3H-purin-6-one …
Galsulfase
Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. Galsulfase is a glycoprotein with a molecular weight of approximately 56 kD. The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate...
Approved
Investigational
Matched Synonyms: … N-acetylgalactosamine-4-sulfatase, recombinant human …
Matched Description: … Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant …
Matched Description: … Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant …
Prochlorperazine
Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.[label] It mainly works by depressing the chemoreceptor trigger zone and blocking...
Approved
Vet approved
Matched Synonyms: … 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine ... 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine ... 3-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine …
Matched Iupac: … 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine …
Matched Iupac: … 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine …
Eluxadoline
Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D). The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central nervous system and peripherally in the gastrointestinal system. Agonism of peripheral...
Approved
Investigational
Matched Synonyms: … 5-({(4-carbamoyl-2,6-dimethyl-L-phenylalanyl)[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino}methyl)-2 …
Matched Iupac: … 5-{[(2S)-2-amino-3-(4-carbamoyl-2,6-dimethylphenyl)-N-[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]propanamido …
Matched Iupac: … 5-{[(2S)-2-amino-3-(4-carbamoyl-2,6-dimethylphenyl)-N-[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]propanamido …
Phenolphthalein
Phenolphthalein was withdrawn in Canada due to concerns with carcinogenicity in 1997.
Approved
Withdrawn
Matched Synonyms: … 3,3-Bis(4-hydroxyphenyl)phthalide …
Matched Iupac: … 3,3-bis(4-hydroxyphenyl)-1,3-dihydro-2-benzofuran-1-one …
Matched Products: … FITALIN 50 MG TABLET, 20 ADET …
Matched Iupac: … 3,3-bis(4-hydroxyphenyl)-1,3-dihydro-2-benzofuran-1-one …
Matched Products: … FITALIN 50 MG TABLET, 20 ADET …
Displaying drugs 76 - 100 of 8829 in total