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Displaying drugs 976 - 1000 of 1863 in total
An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
Approved
Withdrawn
Matched Synonyms: … d-Catechin ... D-Catechol ... D-(+)-Catechin …
Matched Description: … An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin …
Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.
Experimental
Matched Synonyms: … d-Bicuculline …
Matched Description: … , Adlumia fungosa, Fumariaceae, and several Corydalis species. ... It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria …
An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
Investigational
Matched Synonyms: … DNJ ... D-1-deoxynojirimycin ... 1,5-deoxy-1,5-imino-D-mannitol …
Matched Description: … An alpha-glucosidase inhibitor with antiviral action. …
Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral liquid, and other drug products, and was withdrawn due to...
Approved
Investigational
Withdrawn
Matched Description: … liquid, and other drug products, and was withdrawn due to its association with potentially fatal agranulocytosis ... , Norway and Australia. ... It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. …
Matched Mixtures name: … NEOSEDAL-DUO ... DIPIRONA N- BULTILBROMURO DE HIOSCINA ... N-BUTIL BROMURO DE HIOSCINA20MG + DIPIRONA 2500 MG/5 ML …
Matched Products: … LIGARIL - D ... LIGARIL D- TABLETAS ... LIGARIL -D TABLETAS …
Fluoroestradiol F-18 is an imaging agent used with positron emission tomography (PET) to detect estrogen receptor-positive breast cancer lesions. The ability to image ER-positive tumors in vivo is advantageous in that, while helping to visualize tumor progression/regression, it may also be used to assess for heterogeneity in ER expression across...
Approved
Matched Synonyms: … F-18 16 alpha-Fluoroestradiol ... 16-alpha-(18-Fluoro)-17betaestradiol ... 16-alpha-(18F)Fluoro-17beta-estradiol …
Matched Description: … PETNET Solutions, Inc. and Zionexa USA under the brand name Cerianna. ... [A203912] Fluoroestradiol F-18 was first granted FDA approval in May 2020, and will be developed by …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Approved
Matched Synonyms: … Bortezomib D-mannitol ester ... Bortezomib D-mannitol symmetrical ester …
Matched Name: … Bortezomib D-mannitol …
Gluconolactone is a naturally-occurring food additive used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent. It is a cyclic ester of D-gluconic acid. Pure gluconolactone is a white odorless crystalline powder.
Approved
Experimental
Matched Synonyms: … 1,5-D-gluconolactone ... D-glucono-1,5-lactone ... D-threo-Aldono-1,5-lactone …
Matched Description: … It is a cyclic ester of D-gluconic acid. Pure gluconolactone is a white odorless crystalline powder. …
Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Approved
Matched Synonyms: … r-INF-alpha ... rIFN-alpha-2b ... Interferon alpha-2B …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Interferon alpha ... Interferon-alpha
Experimental
Matched Synonyms: … β-D-galactosamine ... 2-amino-2-deoxy-β-D-galactopyranose ... 2-amino-2-deoxy-beta-D-galactopyranose …
Matched Name: … beta-D-Galactosamine …
A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland,...
Experimental
Investigational
Matched Synonyms: … hypoxanthine D-riboside ... 9-β-D-ribofuranosylhypoxanthine ... 9-β-D-ribofuranosyl-9H-purin-6-ol …
Matched Description: … It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Nucleic Acids, Nucleotides, and Nucleosides …
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines (diiodotyrosine) in the thyroglobulin. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form triiodothyronine which exerts a broad spectrum...
Approved
Investigational
Matched Synonyms: … D-thyroxine ... O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine …
Matched Description: … Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. ... Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Zeranol is a non-steroidal estrogen agonist. It is a mycotoxin, derived from fungi in the Fusarium family, and may be found as a contaminant in fungus-infected crops. It is 3-4x more potent as an estrogen agonist than the related compound zearalenone.
Experimental
Vet approved
Matched Synonyms: … alpha-Zeranol …
Matched Description: … It is a mycotoxin, derived from fungi in the Fusarium family, and may be found as a contaminant in fungus-infected …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Urolithin A is a metabolite of ellagic acid. It has been demonstrated to stimulate mitophagy and improve muscle health in old animals and in preclinical models of aging.
Investigational
Matched Synonyms: … 3,8-Hydroxydibenzo-alpha-pyrone …
Matched Description: … It has been demonstrated to stimulate mitophagy and improve muscle health in old animals and in preclinical …
Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. Tridecactide, along with metenkefalin, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]
Investigational
Matched Synonyms: … alpha-1-13-corticotropin, human …
Matched Description: … Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte ... stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. …
Investigational
Matched Synonyms: … alpha-Solasonine …
Bifonazole is an azole antifungal drug.
Approved
Investigational
Matched Synonyms: … (+-)-1-(p,alpha-Diphenylbenzyl)imidazole ... 1-(p,alpha-Diphenylbenzyl)imidazole ... 1-(alpha-(4-Biphenylyl)benzyl)imidazole …
Matched Categories: … Imidazole and Triazole Derivatives …
Experimental
Matched Synonyms: … alpha-Ketomalonic acid …
Investigational
Matched Synonyms: … (.alpha.r)-.gamma. ... )-n-((1r)-1-phenylethyl)-, (.alpha.r)- ... )-n-((1r)-1-phenylethyl)-(.alpha.r)-(1,4'-bipiperidine)-1'-butanamide …
Dimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis.[A253942,L43752] The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood. It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor...
Approved
Investigational
Matched Description: … agent for multiple sclerosis approved by the FDA, following [fingolimod] and [teriflunomide]. ... [L43752] Dimethyl fumarate is marketed under the brand name Tecfidera, and it was the third oral disease-modifying …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … D-FUMARIC 240 CAPSULAS DE LIBERACIÓN RETARDADA 240 MG ... D-FUMARIC 120 CAPSULAS DE LIBERACION RETARDADA 120 MG …
Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha-chain of r-hCG is identical...
Approved
Matched Synonyms: … Choriogonadotropin alpha
Matched Description: … with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ... and LH. ... ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Sex Hormones and Modulators of the Genital System …
A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
Approved
Investigational
Matched Synonyms: … alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanol ... alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol …
Matched Description: … A muscarinic antagonist that has effects in both the central and peripheral nervous systems. ... It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. ... It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine …
Matched Products: … AKINETON® TABLETA DE LIBERACION PROLONGADA …
Investigational
Matched Synonyms: … (4-{(E)-3-(4-fluorophenyl)-3-[4-(3-morpholin-4-yl-prop-1ynyl)phenyl]allyloxy}-2-methylphenoxy)acetate
Experimental
Matched Name: … ALPHA-(2,6-DICHLOROPHENYL)-ALPHA-(2-ACETYL-5-METHYLANILINO)ACETAMIDE …
Experimental
Matched Synonyms: … Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate ... 5-Quinolinepropanoic acid, 8-hydroxy-alpha-(2-propyn-1-ylamino)-, ethyl ester …
Matched Name: … Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate …
N4-Hydroxyctidine, or EIDD-1931, is a ribonucleoside analog which induces mutations in RNA virions.[A193008,A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and phage. It has shown antiviral activity against Venezuelan equine encephalitis virus, and the human coronavirus HCoV-NL63 in vitro. N4-hydroxycytodine has been...
Experimental
Matched Synonyms: … β-D-N4-hydroxycytidine ... beta-D-N-4-Hydroxycytidine ... Beta-D-N4-hydroxycytidine …
Matched Description: … in mice and human airway epithelial cells. ... A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and ... [A193023] It has shown antiviral activity against Venezuelan equine encephalitis virus,[A193008] and
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Displaying drugs 976 - 1000 of 1863 in total