Displaying drugs 10376 - 10400 of 14724 in total
AMG-208
AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and Oncology Patients, among others.
Investigational
Matched Description: … AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and …
Polycarbophil
Polycarbophil calcium is a synthetic polymer manufactured from the cross-linking of polyacrylic acid with divinyl glycol and a calcium counter-ion.
Polycarbophil calcium is a stool stabilizer used to treat constipation. This drug may also be used to help relieve the symptoms of irritable bowel syndrome or diarrhea.
Less gas and...
Experimental
Matched Description: … Less gas and bloating compared to psyllium laxative products, but can cause heartburn, and belly cramps ... It is insoluble in water, dilute acids, and dilute alkali. ... is a synthetic polymer manufactured from the cross-linking of polyacrylic acid with divinyl glycol and …
Dirithromycin
Dirithromycin is a macrolide glycopeptide antibiotic used to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsillitis, and even skin infections.
Experimental
Matched Description: … to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsillitis, and …
Matched Categories: … Macrolides, Lincosamides and Streptogramins …
Matched Categories: … Macrolides, Lincosamides and Streptogramins …
Methapyrilene
Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
Withdrawn
Matched Description: … Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979. …
Matched Categories: … Hypnotics and Sedatives …
Matched Categories: … Hypnotics and Sedatives …
Tifuvirtide
Tifuvirtide is the first members of a new class of anti-HIV drugs which is also called fusion inhibitors. It has received fast-track designation from the FDA and is in Phase I/II clinical testing.
Investigational
Matched Description: … It has received fast-track designation from the FDA and is in Phase I/II clinical testing. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Carboxyamidotriazole
Carboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others.
Investigational
Matched Description: … been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Lomerizine
Lomerizine is a diphenylmethylpiperazine calcium channel blocker[A245378, A245383] with relatively selective central nervous system (CNS) effects. This drug is used to prophylactically treat migraines[A245368, A245373] and is also being investigated against eye-related diseases that are associated with local circulatory disturbances, an example being normal-tension glaucoma.
Experimental
Matched Description: … [A245383]
This drug is used to prophylactically treat migraines[A245368, A245373] and is also being …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Categories: … Calcium-Regulating Hormones and Agents …
gamma-Tocopherol
gamma-Tocopherol is under investigation in clinical trial NCT00836368 (In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics).
Investigational
Matched Categories: … Diet, Food, and Nutrition …
Chlormadinone acetate
Chlormadinone acetate is a progesterone derivative first synthesized in 1961. In the US, chlormadinone acetate was formerly marketed as a component of the combination drug products Estalor-21 and C-Quens. However, the use of these drugs was associated with the development of mammary tumors in dogs. In 1972, the FDA withdrew...
Experimental
Withdrawn
Matched Description: … chlormadinone acetate was formerly marketed as a component of the combination drug products Estalor-21 and ... Chlormadinone acetate continues to be used in other countries due to its high contraceptive efficacy and …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
AVE-2865
Experimental
Clomethiazole
Clomethiazole is a well-established γ-aminobutyric acid (GABAA)-mimetic drug. It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol withdrawal. It is a drug which is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic, muscle relaxant and anticonvulsant. It...
Investigational
Matched Description: … It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol ... is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic, muscle relaxant and ... It is also used for the management of agitation, restlessness, short-term insomnia and Parkinson's disease …
Matched Categories: … Hypnotics and Sedatives …
Matched Categories: … Hypnotics and Sedatives …
Omecamtiv Mecarbil
Omecamtiv Mecarbil has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic Heart Failure, and History of Chronic Heart Failure, among others.
Investigational
Matched Description: … Omecamtiv Mecarbil has been used in trials studying the treatment and basic science of Heart Failure, ... Echocardiogram, Pharmacokinetics, Chronic Heart Failure, and History of Chronic Heart Failure, among …
Apricoxib
Apricoxib has been used in trials studying the treatment and prevention of Lung Cancer, Breast Cancer, Pancreatic Cancer, Non Small Cell Lung Cancer, and Metastatic Pancreatic Cancer, among others.
Investigational
Matched Description: … Apricoxib has been used in trials studying the treatment and prevention of Lung Cancer, Breast Cancer ... , Pancreatic Cancer, Non Small Cell Lung Cancer, and Metastatic Pancreatic Cancer, among others. …
AGG-523
AGG-523 is under investigation in clinical trial NCT00380900 (Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses in Healthy subjects and in subjects with osteoarthritis).
Investigational
Matched Description: … Pharmacodynamics of Multiple Ascending Doses in Healthy subjects and in subjects with osteoarthritis ... investigation in clinical trial NCT00380900 (Study Evaluating the Safety, Tolerability, Pharmacokinetics and …
PSN9301
PSN9301 is an oral small molecule inhibitor of Dipeptidyl Peptidase IV (DP-IV), being developed for the treatment of type 2 diabetes. PSN9301 has a very rapid onset and a relatively short duration of action, and available pre-clinical and clinical data indicate that it may be an ideal product candidate for...
Investigational
Matched Description: … PSN9301 has a very rapid onset and a relatively short duration of action, and available pre-clinical ... and clinical data indicate that it may be an ideal product candidate for meal-related dosing. …
(2,6-Dimethylphenoxy)acetic acid
Experimental
GC-376 free acid
GC-376 is a 3C-like protease (3CLpro or Mpro) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells . The compound is known as a direct acting antiviral (DAA) for coronaviruses, and was initially developed using structure-guided design to combat MERS-Cov...
Experimental
Matched Description: … -376 is a 3C-like protease (3CLpro or Mpro) inhibitor that stops the cleavage and ... activation of functional viral proteins required for replication and transcription in host cells[A219036 ... The compound is known as a direct acting antiviral (DAA) for coronaviruses, and was initially developed …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Afimetoran
Afimetoran is an immunomodulator and an antagonist of toll-like receptors 7 and 8.[L32018, L32023] It is also is under investigation in clinical trial NCT04269356 (Study to Assess the Way the Body Absorbs, Distributes, Breaks Down and Eliminates Radioactive BMS-986256 in Healthy Male Participants).
Investigational
Matched Description: … Afimetoran is an immunomodulator and an antagonist of toll-like receptors 7 and 8. ... investigation in clinical trial NCT04269356 (Study to Assess the Way the Body Absorbs, Distributes, Breaks Down and …
WIN 55212-2
WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of...
Experimental
Matched Description: … It activates p42 and p44 MAP kinase via receptor-mediated signaling. …
Matched Categories: … Cannabinoids and similars ... Calcium-Regulating Hormones and Agents …
Matched Categories: … Cannabinoids and similars ... Calcium-Regulating Hormones and Agents …
Displaying drugs 10376 - 10400 of 14724 in total