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Displaying drugs 1026 - 1050 of 1195 in total

Abrocitinib

Abrocitinib is an oral small-molecule inhibitor of Janus kinase 1 (JAK1). Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and immune cell function. The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signalling pathway plays a central role in the pathogenesis of a variety of...
Approved
Investigational
Matched Description: … Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and ... [L39774] The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signalling pathway ... plays a central role in the pathogenesis of a variety of autoimmune and inflammatory diseases, including …
Matched Products: … CİBİNQO 50 MG FİLM KAPLI TABLET, 28 ADET ... CİBİNQO 200 MG FİLM KAPLI TABLET, 28 ADET ... CİBİNQO 100 MG FİLM KAPLI TABLET, 28 ADET …

Vardenafil

Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.[L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the...
Approved
Matched Description: … PDE5 inhibitors, such as vardenafil, inhibit the degradation of cGMP and allow increased blood flow into ... selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and ... [L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … VAREKSİL 5 MG FİLM KAPLI TABLET, 4 ADET ... VAREKSİL 10 MG FİLM KAPLI TABLET, 4 ADET ... VAREKSİL 20 MG FİLM KAPLI TABLET, 2 ADET …

Finasteride

Finasteride is a synthetic 4-azasteroid compound and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT). It works in a similar fashion as dutasteride, which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. Finasteride is an orally active drug...
Approved
Matched Description: … Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase ... first approved by the FDA in 1992 for the treatment of benign prostatic hyperplasia to improve symptoms and ... [L6244] Finasteride is commonly marketed under the brand names Propecia and Proscar to be used aloneo …
Matched Categories: … Genito Urinary System and Sex Hormones ... Skin and Mucous Membrane Agents ... doxazosin and finasteride ... alfuzosin and finasteride ... finasteride and tadalafil …
Matched Products: … FINASTERID - CT 5MG FILM ... FINASTERID ARISTO 5MG FILM ... FINARID 5 MG FİLM TABLET, 30 ADET …

Enoxacin

A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Approved
Investigational
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Products: … REKSOTİN 200 MG FİLM TABLET, 6 TABLET ... REKSOTİN 400 MG FİLM TABLET, 14 TABLET …

Luseogliflozin

Luseogliflozin has been used in trials studying the treatment of Diabetes Melltius, Type 2.
Investigational
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Lusefi 5mg film-coated tablet ... Lusefi 2.5mg film-coated tablet …

Frovatriptan

Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.
Approved
Investigational
Matched Description: … Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head. …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … MIGREX 2.5 MG FILM TABLET, 12 ADET ... MIGREX 2.5 MG FILM TABLET, 3 ADET ... MIGREX 2.5 MG FILM TABLET, 6 ADET …

Eletriptan

Eletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.
Approved
Investigational
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … RELPAX 40 MG FILM TABLET, 2 ADET ... RELPAX 40 MG FILM TABLET, 4 ADET ... RELPAX 40 MG FILM TABLET, 1 ADET …

Asciminib

Asciminib is a tyrosine kinase inhibitor (TKI) used in the treatment of chronic-phase Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). More specifically, it is an inhibitor of the ABL1 kinase activity of the BCR-ABL1 fusion protein which serves as a driver of CML proliferation in most patients with the disease....
Approved
Investigational
Matched Description: … Existing inhibitors of ABL compete at the ATP binding sites of these proteins and can be classified into ... those that target the active conformation of the kinase domain ([dasatinib], [bosutinib]) and those ... in that it acts as an allosteric inhibitor, binding at the myristoyl pocket of the BCR-ABL1 protein and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … AZEVAY 20 MG FİLM KAPLI TABLET , 60 ADET ... AZEVAY 40 MG FİLM KAPLI TABLET , 60 ADET …

Aceclofenac

Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … AIRTAL FILM COATED TABLETS 100mg ... Airtal 100mg Film-coated Tablet ... ASEC 100 MG FILM TABLET, 20 ADET …

Sofosbuvir

Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Description: … for its high replicative rate and genetic diversity [A19594]. ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... count, and neuropsychiatric effects [A19635]. …
Matched Mixtures name: … Ledipasvir and Sofosbuvir ... Sofosbuvir and Velpatasvir ... VOSEVI FILM-COATED TABLETS 400MG/100MG/100MG …
Matched Categories: … sofosbuvir and ledipasvir ... sofosbuvir and velpatasvir ... Nucleic Acids, Nucleotides, and Nucleosides ... sofosbuvir, velpatasvir and voxilaprevir …
Matched Products: … Sovaldi 400mg Film-Coated Tablets ... GRATEZIANO 400 MG FILM COATED TABLET ... SOVALDI 400 MG FILM KAPLI TABLET, 84 ADET …

Moclobemide

A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA) or selective serotonin reuptake inhibitors (SSRIs)....
Approved
Investigational
Matched Description: … Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide ... is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA ... Due to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than …
Matched Categories: … Benzamides and benzamide derivatives …
Matched Products: … Aurorix Film Coated Tablet 150mg ... Aurorix Film Coated Tablet 300mg ... AURORIX 150 MG FILM KAPLI TABLET, 30 ADET …

Valganciclovir

Valganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections. As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.
Approved
Investigational
Matched Description: … After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases …
Matched Categories: … Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … CITOVIR 450 MG FILM TABLET, 60 ADET ... VALCYTE 450 MG FILM TABLET, 60 ADET ... AVALCEPT 450 MG FILM KAPLI TABLET, 60 ADET …

Vemurafenib

Vemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E. It exerts its function by binding to the ATP-binding domain of the mutant BRAF. Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann...
Approved
Matched Description: … [A31270] Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … ZELBORAF 240 MG FILM KAPLI TABLET ,56 FILM KAPLI TABLET ... Zelboraf 240mg film-coated tablets …

Udenafil

Udenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It has been approved in South Korea and will be marketed under the brand name Zydena. It is not yet approved for use in the U.S., E.U., or Canada.
Approved
Investigational
Matched Description: … It has been approved in South Korea and will be marketed under the brand name Zydena. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … ZYDENA 100 MG FILM TABLET, 2 ADET ... ZYDENA 100 MG FILM TABLET, 4 ADET …

Tamoxifen

Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.[L7799,L7802] Tamoxifen may no longer be the preferred treatment for these types of cancers...
Approved
Matched Description: … treatment for these types of cancers as patients generally have better survival, side effect profiles, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … NOLVADEX 10 MG FILM TABLET, 30 ADET ... NOLVADEX 10 MG FILM TABLET, 250 ADET ... TAMOXIT 20 MG FİLM KAPLI TABLET (TAMOFEN), 100 TABLET …

Vilazodone

Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain . Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Approved
Matched Description: … (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. ... Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine ... Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. …
Matched Categories: … Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … ZİLADONE 10 MG FİLM KAPLI TABLET, 30 ADET ... ZİLADONE 20 MG FİLM KAPLI TABLET, 30 ADET ... ZİLADONE 40 MG FİLM KAPLI TABLET, 30 ADET …

Lapatinib

Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer. It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine. Lapatinib is a...
Approved
Investigational
Matched Description: … such as breast and lung cancer. ... Lapatinib is a human epidermal growth factor receptor type 2 (HER2/ERBB2) and epidermal growth factor ... Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … TYKERB 250 MG FILM TABLET, 70 ADET ... TYKERB FILM-COATED TABLETS 250MG …

Metoprolol

Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date,...
Approved
Investigational
Matched Description: … Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives ... widely prescribed in the Netherlands, New Zealand, and the US. ... [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is …
Matched Mixtures name: … IMPLICOR 50MG/5MG FILM-COATED TABLETS ... IMPLICOR 25MG/5MG FILM-COATED TABLETS ... IMPLICOR FILM-COATED TABLET 25 mg/5 mg …
Matched Categories: … Beta Blocking Agents and Thiazides ... Beta blocking agents and calcium channel blockers ... Beta Blocking Agents, Selective, and Thiazides ... metoprolol and felodipine ... metoprolol and ivabradine …
Matched Products: … Metoprolol Tartrate film coated ... PROBLOK 100 MG FİLM TABLET, 20 ADET ... LOPRESOR 100 MG FILM TABLET, 20 ADET …

Drospirenone

Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Description: … [L7973] Most recently, it was approved by both Health Canada and the FDA in combination with [Estetrol ... ,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to control acne and ... Some studies have demonstrated a significantly increased risk and some demonstrating no risk of thromboembolic …
Matched Mixtures name: … Drospirenone and Ethinyl Estradiol ... Drospirenone and Ethinyl Estradiol ... Drospirenone and Ethinyl Estradiol …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... Genito Urinary System and Sex Hormones ... drospirenone and estetrol ... drospirenone and estrogen ... drospirenone and ethinylestradiol …
Matched Products: … SLINDA FILM-COATED TABLETS 4MG ... ZLYNDA 4 MG FİLM KAPLI TABLET, 28 ADET ... ZLYNDA 4 MG FİLM KAPLI TABLET, 84 ADET …

Raloxifene

Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Description: … uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation. ... generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and ... and it does not cause endometrial proliferation. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … ELASTA 60mg FILM-COATED TABLETS ... Raloxon Film-coated Tablets 60 mg ... ROXIMAX 60 MG FİLM TABLET, 28 ADET …

Tenoxicam

Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
Approved
Matched Description: … and control acute pain. ... Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ARTOXAN 20 MG FILM TABLET ,10 ADET ... TILKETEM FILM TABLET, 10 ADET ... TILKETEM FILM TABLET, 30 ADET …

Fluvoxamine

Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder. Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised...
Approved
Investigational
Matched Description: … It was launched in the US in December 1994 and in Japan in June 1999. ... Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Products: … LUVOX 50MG FILM COATED TABLET ... LUVOX 100MG FILM COATED TABLET ... REVOXIN 50MG FILM TABLET, 30 ADET …

Rifaximin

Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, meaning that the drug will not pass the gastrointestinal wall into the circulation as is common for other types of orally administered antibiotics. It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction in risk of...
Approved
Investigational
Matched Description: … It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction ... encephalopathy recurrence; as well as diarrhea-predominant irritable bowel syndrome (IBS-D) in adult women and …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … HEPAZEC 550 MG FILM TABLET,56-FILM-TABLET ... XIFAXAN Film-coated Tablet 550mg ... COLIDUR 200 MG FILM TABLET, 24 ADET …

Mianserin

A tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.
Approved
Investigational
Matched Products: … MIANSERIN-REMEDICA 30mg Film-Coated Tablets ... MIANSERIN-REMEDICA 10mg Film-Coated Tablets ... TOLVON 30 MG FİLM KAPLI TABLET, 14 ADET …

Dydrogesterone

A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.
Approved
Investigational
Withdrawn
Matched Description: … Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does …
Matched Mixtures name: … Femoston Conti 1/5mg Film-Coated Tablet ... Femoston Conti 0.5mg/2.5mg Film Coated Tablet …
Matched Categories: … Genito Urinary System and Sex Hormones ... dydrogesterone and estrogen ... dydrogesterone and estrogen ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Progestogens and Estrogens, Sequential Preparations …
Matched Products: … DUPHASTON TABLET 10 mg (Film-coated) ... DUPHASTON 10 MG FİLM KAPLI TABLET, 20 ADET …
Displaying drugs 1026 - 1050 of 1195 in total