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Displaying drugs 1026 - 1050 of 1373 in total

Anidulafungin

Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in February 21, 2006; it was previously known as LY303366. There is preliminary evidence that it has a similar safety profile to caspofungin.
Approved
Investigational
Matched Description: … Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … ANIDACCORD 100 POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100 MG ... ERAXIS 100MG FOR INJECTION ... Eraxis 100mg For Injection …

Etoposide

A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division,...
Approved
Matched Description: … Etoposide acts primarily in the G2 and S phases of the cell cycle. ... Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. …
Matched Salts name: … Etoposide phosphate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … MYLAN ETOPOSIDE CONCENTRATE FOR SOLUTION FOR INJECTION 20MG/ML ... ETOPOSIDE CONCENTRATE FOR SOLUTION FOR INJECTION 20mg/ml ... SEDOL - Etoposide Concentrate for Solution for Infusion 20 mg/ml …

Cholestyramine

Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. Cholestyramine resin is quite hydrophilic, but insoluble in water.
Approved
Investigational
Matched Categories: … Hypolipidemic Agents Indicated for Hyperlipidemia ... Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia …
Matched Products: … Cholestyramine Powder for Suspension ... Cholestyramine for Oral Suspension ... PHL-cholestyramine Powder for Suspension 400gm/can …

Sotrovimab

Sotrovimab (VIR-7831), also known as GSK4182136, is a monoclonal antibody that can neutralize the SARS-CoV-2 virus. Sotrovimab was initially been granted emergency use authorization (EUA) to treat mild-to-moderate COVID-19 on May 26, 2021, based on interim results from a clinical trial, where sotrovimab was found to reduce the risk of...
Approved
Investigational
Matched Description: … [L34425, L34430, L34440] However, in April 2022, the FDA removed the EUA for sotrovimab due to the rising …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Antiinfectives for Systemic Use ... Approved Treatments for COVID-19 ... Experimental Unapproved Treatments for COVID-19 …
Matched Products: … Sotrovimab for Injection …

Bicisate

Bicisate, also known as ethyl cysteinate dimer (ECD), is a N,N'-1,2-ethylene-di-yl-bis-L-cysteinate diethyl ester. It is used in conjunction with technetium Tc99m as a tracer to measure cerebral blood flow with single-photon emission computed tomography (SPECT). The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl...
Approved
Investigational
Matched Description: … [A32374] The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl and FDA-approved …
Matched Products: … NEUROLITE KIT FOR THE PREPARATION OF Tc99m BICISATE FOR INJECTION …

Micafungin

Micafungin is an antifungal drug. It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
Approved
Investigational
Matched Description: … It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … MYCAMINE POWDER FOR SOLUTION FOR INFUSION 50MG/VIAL ... Mycamine 50 mg/vial powder for solution for infusion ... Micafungin for Injection …

Romosozumab

Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and patients who have failed in other treatments or are intolerant to other osteoperosis therapies . Romosozumab prevents bone resorption and induces the formation of bone though it is associated...
Approved
Investigational
Matched Description: … In a comparison study of post menopausal women with osteoporosis and a past fracture, romosozumab for ... 12 months followed by alendronic acid for 12 months was superior to alendronic acid alone for 24 months ... increased risk of cardiac death, heart attack, and stroke in one study[L5921,L5924]. …
Matched Categories: … Drugs for Treatment of Bone Diseases ... Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105 MG/1.17 ML ... EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105MG/1.17ML …

Rasburicase

Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.
Approved
Investigational
Matched Description: … The cDNA coding for rasburicase was cloned from a strain of _Aspergillus flavus_. …
Matched Categories: … Enzymes and Coenzymes ... Detoxifying Agents for Antineoplastic Treatment …
Matched Products: … FASTURTEC POWDER FOR SOLUTION FOR INFUSION 1.5 mg/vial …

Gadoxetic acid

Gadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection. Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug. Gadoxetate is a...
Approved
Matched Description: … hepatobiliary phase and thus has different pharmacokinetic and pharmacodynamic properties compared to ... forms a stable complex with it to make up the drug. ... , gadoxetate disodium, is used for intravenous injection. …
Matched Products: … Primovist 0.25 mmol/ml Solution for injection ... PRIMOVIST 0.25 MMOL/ML, SOLUTION FOR INJECTION …

Albumin human

Human serum albumin is the primary protein present in human blood plasma. The main function of albumin is to maintain the oncotic pressure of blood . It binds to water, cations (such as Ca2+, Na+ and K+), fatty acids, hormones, bilirubin, thyroxine (T4) and pharmaceuticals (including barbiturates). Albumin represents approximately...
Approved
Matched Description: … This is a biosimilar drug to existing human serum albumin and was approved for a biological license at ... ) and pharmaceuticals (including barbiturates). ... both 5% and 25% concentrations by the FDA on June 21, 2018 [L3101]. …
Matched Mixtures name: … Sterile Diluent for Allergenic Extract …
Matched Categories: … Blood and Related Products ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …
Matched Products: … ALBURX SOLUTION FOR INFUSION 5% ... ALBUNORM SOLUTION FOR INFUSION 5% ... ALBURX SOLUTION FOR INFUSION 20% …

Ocrelizumab

Ocrelizumab is a CD20-directed cytolytic antibody indicated for the treatment of patients with primary progressive or relapsing forms of multiple sclerosis (MS). It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets B-cells that express the CD20 antigen. Compared to non-humanized CD20 antibodies such as rituximab, ocrelizumab is...
Approved
Investigational
Matched Description: … PPMS in both the US and Canada. ... relapse rates and reduced worsening of disability compared to [interferon beta-1a]. ... with MS, and leads to the gradual worsening of neurologic disability from symptom onset, often without …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … OCREVUS 300mg/10mL Concentrate for Solution for Infusion …

Ferrous gluconate

Approved
Matched Mixtures name: … Somarexin and C 1000 ... Magnum-75 Vitamin and Mineral Supplement ... Multi-force for Women Tab …
Matched Categories: … Blood and Blood Forming Organs ... ferrous gluconate and folic acid …
Matched Products: … LOSFERRON FORT EFERVESAN TABLET, 30 ADET …

Pyridoxal

The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. [PubChem]
Experimental
Nutraceutical
Matched Synonyms: … 2-methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine …
Matched Description: … The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme ... for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic …

Dulaglutide

Dulaglutide, marketed by Eli Lilly as Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and exercise in the management of 2 diabetes (T2DM). Dulaglutide was initially approved by the FDA in 2014, and...
Approved
Investigational
Matched Description: … [A236070] Dulaglutide was initially approved by the FDA in 2014, and in February 2020 was approved for ... use in patients with T2DM and multiple cardiovascular risk factors for the prevention of cardiovascular ... agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Trulicity 1.5mg solution for injection in pre-filled pen ... Trulicity 0.75mg solution for injection in pre-filled pen …

Peginterferon alfa-2a

Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Description: … 36% for genotype 1 and 59% for genotypes 2-6 after 48 weeks of treatment. ... development of endocrine and autoimmune disorders, retinopathies, cardiovascular and neuropsychiatric ... -2a for the treatment of Hepatitis C [A19593]. …
Matched Categories: … Treatments for Hepatitis C ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … PEGASYS PRE-FILLED SYRINGE FOR INJECTION 180 mcg/0.5 ml ... PEGASYS PRE-FILLED SYRINGE FOR INJECTION 135 mcg/0.5 ml …

Lutein

Lutein is an xanthophyll and one of 600 known naturally occurring carotenoids. Lutein is synthesized only by plants and like other xanthophylls is found in high quantities in green leafy vegetables such as spinach, kale and yellow carrots. In green plants, xanthophylls act to modulate light energy and serve as...
Approved
Investigational
Nutraceutical
Matched Description: … to deal with triplet chlorophyll (an excited form of chlorophyll), which is overproduced at very high ... leafy vegetables such as spinach, kale and yellow carrots. ... Lutein is an xanthophyll and one of 600 known naturally occurring carotenoids. …
Matched Products: … Noon for Kids …

Technetium Tc-99m disofenin

Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic purposes. It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary system. It is available as...
Approved
Matched Description: … It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure ... the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary ... Technetium Tc-99m is a metastable nuclear isomer and disofenin is an iminodiacetic acid derivative with …
Matched Categories: … Indicators and Reagents ... Amino Acids, Peptides, and Proteins ... Hepatic and Reticulo Endothelial System …
Matched Products: … Kit for the Preparation of Technetium Tc99m Disofenin …

Flax seed

Flax seed allergenic extract is used in allergenic testing.
Approved
Matched Products: … Flax Seed for Diagnostic Use Only …

Flutemetamol

Flutemetamol is under investigation in clinical trial NCT02353949 (Investigating the Clinical Consequences of Flutemetamol-PET-scanning).
Investigational
Matched Categories: … Indicators and Reagents …
Matched Products: … VIZAMYL SOLUTION FOR INJECTION 150 MBq/mL …

Faricimab

Retinal vascular diseases (RVDs) such as diabetic macular edema (DME), age-related macular degeneration (AMD), and retinal vein occlusion (RVO) are typically caused by retinal ischemia and subsequent neovascularization (NV).[A225985, A225990, A225995] Vascular endothelial growth factor A (VEGF-A) is a well-known mediator of retinal NV, and many currently approved RVD therapies...
Approved
Investigational
Matched Description: … [L42305] In July 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended faricimab ... and diabetic macular edema. ... [L40026] It received subsequent approval for the same indications in Canada in May 2022. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … VABYSMO 6mg/0.05mL Solution for Intravitreal Injection …

Ipilimumab

Ipilimumab is a fully humanized IgG1 monoclonal antibody that blocks cytotoxic T lymphocyte antigen-4 (CTLA-4). Blocking CTLA-4 removes an inhibitory signal from reducing the activity of T lymphocytes.[A35065,A35080,L12126] Ipilimumab was developed by Bristol-Myers Squibb and Medarex. Ipilimumab was granted FDA approval on 25 March 2011.
Approved
Matched Description: … [A35065,A35080,L12126] Ipilimumab was developed by Bristol-Myers Squibb and Medarex. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Monoclonal antibodies and antibody drug conjugates …
Matched Products: … YERVOY 5 mg/ml concentrate for solution for infusion …

Technetium Tc-99m pyrophosphate

A radionuclide imaging agent used primarily in scintigraphy or tomography of the heart to evaluate the extent of the necrotic myocardial process. It has also been used in noninvasive tests for the distribution of organ involvement in different types of amyloidosis and for the evaluation of muscle necrosis in the...
Approved
Matched Iupac: … (99Tc)technetium(4+) ion (phosphonooxy)phosphonate …
Matched Description: … of amyloidosis and for the evaluation of muscle necrosis in the extremities. ... It has also been used in noninvasive tests for the distribution of organ involvement in different types …
Matched Categories: … Indicators and Reagents ... Phosphate salts …
Matched Products: … Kit for the Preparation of Technetium Tc99m Pyrophosphate …

Rumex crispus whole

Rumex crispus whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Mixtures name: … Herborex Fort Lax Liq …
Matched Products: … JEUNCELL a drug for atopic dermatitis …

Levofloxacin

Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Synonyms: … Ofloxacin S-(-)-form …
Matched Description: … [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and ... Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use ... Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... lansoprazole, amoxicillin and levofloxacin …
Matched Products: … For Infusion 5mg/ml ... Levores 5mg/ml Solution for Infusion ... Levofloxacin Kabi 5mg/mL Solution for Infusion …

Fremanezumab

Fremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide (CGRP) for the prevention of migraine headaches. It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. Along with other recently approved anti-CGRP therapies such as galcanezumab, erenumab, and the oral CGRP antagonist...
Approved
Investigational
Matched Description: … Fremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide (CGRP) for ... [L11749] It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. ... [L11779] Along with other recently approved anti-CGRP therapies such as [galcanezumab], [erenumab], and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … AJOVY SOLUTION FOR INJECTION IN PRE-FILLED PEN 225 MG/1.5ML ... AJOVY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 225 MG/1.5ML …
Displaying drugs 1026 - 1050 of 1373 in total