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Displaying drugs 10476 - 10500 of 12014 in total

Viral Macrophage-Inflammatory Protein

Viral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog encoded by human herpesvirus-8. The structure of vMIP consists of 71 residues and is a monomer under most conditions. It helps its virus evade the host immune system through selectively blocking and activating different receptors, preferentially...
Investigational

Firocoxib

Firocoxib is a cycooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug. It currently approved for veterinary use in dogs and horses under the brand names Equioxx and Previcox. Firocoxib was the first COX-2 inhibitor approved by the U.S. Food and Drug Administration for horses. Firocoxib is not intended or approved for use...
Experimental
Vet approved
Matched Iupac: … 3-(cyclopropylmethoxy)-4-(4-methanesulfonylphenyl)-5,5-dimethyl-2,5-dihydrofuran-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Vadastuximab talirine

Vadastuximab Talirine has been used in trials studying the treatment of Acute myeloid leukemia, Myelodysplastic Syndrome, Acute Myelogenous Leukemia, and Acute Promyelocytic Leukemia.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Nefiracetam

Nefiracetam has been used in trials studying the treatment of Alzheimer's Disease.
Investigational
Matched Iupac: … N-(2,6-dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Zatolmilast

BPN-14770 is under investigation in clinical trial NCT02840279 (A Multiple Ascending Dose Study of BPN14770 in Healthy Young and Elderly Male or Female Subjects).
Investigational
Matched Iupac: … 2-(4-{[2-(3-chlorophenyl)-6-(trifluoromethyl)pyridin-4-yl]methyl}phenyl)acetic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Phosphodiesterase 4 Inhibitors …

ONO-8539

ONO-8539 is under investigation in clinical trial NCT01707901 (A Study of the Effect of ONO-8539 on Oesophageal Pain Hypersensitivity in Patients With Non-erosive Reflux Disease).
Investigational
Matched Iupac: … 3-methyl-4-[({6-[N-(2-methylpropyl)1,3-thiazole-2-sulfonamido]-2,3-dihydro-1H-inden-5-yl}oxy)methyl]benzoic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid

Experimental
Matched Name: … 2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid …
Matched Iupac: … (2R)-2-[(N-hydroxyformamido)methyl]-4-methylpentanoic acid …

(3R)-3-ethyl-N-[(4-methylphenyl)sulfonyl]-L-aspartic acid

Experimental
Matched Name: … (3R)-3-ethyl-N-[(4-methylphenyl)sulfonyl]-L-aspartic acid …
Matched Iupac: … (2R,3S)-2-ethyl-3-(4-methylbenzenesulfonamido)butanedioic acid …

4-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDE

Experimental
Matched Name: … 4-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDE …
Matched Iupac: … 4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benzamide …

6-(4-chloro-2-fluoro-3-phenoxybenzyl)pyridazin-3(2H)-one

Experimental
Matched Name: … 6-(4-chloro-2-fluoro-3-phenoxybenzyl)pyridazin-3(2H)-one …
Matched Iupac: … 6-[(4-chloro-2-fluoro-3-phenoxyphenyl)methyl]-2,3-dihydropyridazin-3-one …

Adenylate-3'-phosphate-[[2'-deoxy-uridine-5'-phosphate]-3'-phosphate]

Experimental
Matched Name: … Adenylate-3'-phosphate-[[2'-deoxy-uridine-5'-phosphate]-3'-phosphate] …
Matched Iupac: … ]-4-hydroxyoxolan-3-yl]oxy}phosphonic acid ... {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-[({[({[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin ... -1-yl)-2-[(phosphonooxy)methyl]oxolan-3-yl]oxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl …

Siagoside

Siagoside (Sygen, AGF 2) has been investigated for the treatment of Parkinson Disease. It is a naturally occurring substance in the nerve cell’s membrane that is thought to play a role in cell growth, development, and repair. Siagoside completed phase 2 trials for parkinson's disease (PD) treatment. Sygen appears to...
Investigational
Matched Iupac: … N-[(2S,3R,4E)-1-{[(2R,3R,4R,5S,6R)-5-[(2S,4S,4'aR,5R,5'S,6R,7'R,8'S,8'aS)-5-acetamido-8'-{[(2S,3R,4R, ... 5R,6R)-3-acetamido-5-hydroxy-6-(hydroxymethyl)-4-{[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl ... pyrano[3,4-b][1,4]dioxin]-3'-oneoxy]-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3-hydroxyoctadec-4- ... )oxan-2-yl]oxy}oxan-2-yl]oxy}-4-hydroxy-7'-(hydroxymethyl)-6-[(1R,2R)-1,2,3-trihydroxypropyl]-hexahydrospiro …

11-[(MERCAPTOCARBONYL)OXY]UNDECANOIC ACID

Experimental

Mazaticol

Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Telotristat

A tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat.
Experimental
Matched Iupac: … (2S)-2-amino-3-(4-{2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy ... ]pyrimidin-4-yl}phenyl)propanoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Flortaucipir

Flortaucipir is under investigation in clinical trial NCT03507257 (Longitudinal Early-onset Alzheimer's Disease Study Protocol).
Investigational
Matched Iupac: … 2-fluoro-5-{5H-pyrido[4,3-b]indol-7-yl}pyridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

L-proline betaine

Experimental
Matched Iupac: … (2S)-1,1-dimethylpyrrolidin-1-ium-2-carboxylate …

S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine

Experimental
Matched Name: … S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine …

4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline

Experimental
Matched Name: … 4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline …
Matched Iupac: … 6,7-dimethoxy-N-[3-(methylsulfanyl)phenyl]quinazolin-4-amine …

(S)-2-Amino-3-(6h-Selenolo[2,3-B]-Pyrrol-4-Yl)-Propionic Acid

Experimental
Matched Name: … (S)-2-Amino-3-(6h-Selenolo[2,3-B]-Pyrrol-4-Yl)-Propionic Acid …
Matched Iupac: … (2S)-2-amino-3-{6H-selenopheno[2,3-b]pyrrol-4-yl}propanoic acid …

N-BENZYLOXYCARBONYL-ALA-PRO-3-AMINO-4-PHENYL-BUTAN-2-OL

Experimental
Matched Name: … N-BENZYLOXYCARBONYL-ALA-PRO-3-AMINO-4-PHENYL-BUTAN-2-OL …
Matched Iupac: … benzyl N-[(2S)-1-[(2S)-2-{[(2S,3R)-3-hydroxy-1-phenylbutan-2-yl]carbamoyl}pyrrolidin-1-yl]-1-oxopropan …

3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one

Experimental
Matched Name: … 3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one …
Matched Iupac: … 3-(2,6-difluorophenyl)-2-(methylsulfanyl)-3,4-dihydroquinazolin-4-one …

Ethoxzolamide

Ethoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. Its pharmacological activity thus confers the risk for hypokalemia.
Withdrawn
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Seviteronel

Seviteronel has been used in trials studying the treatment of CRPC, Prostate Cancer, and Castration-resistant Prostate Cancer.
Investigational
Matched Iupac: … (1S)-1-[6,7-bis(difluoromethoxy)naphthalen-2-yl]-2-methyl-1-(1H-1,2,3-triazol-5-yl)propan-1-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

6-(Dihydroxy-Isobutyl)-Thymine

Experimental
Matched Iupac: … 6-[3-hydroxy-2-(hydroxymethyl)propyl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Displaying drugs 10476 - 10500 of 12014 in total