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Displaying drugs 1051 - 1075 of 1648 in total
Investigational
Matched Synonyms: … Benzeneacetic acid, 4-(2-(3-carboxy-4-hydroxyphenyl)diazenyl)- …
Ethyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)
Withdrawn
Matched Synonyms: … Ethyl bis(4-hydroxy-2-oxo-2h-1-benzopyran-3-yl)acetate
Matched Iupac: … ethyl 2,2-bis(4-hydroxy-2-oxo-2H-chromen-3-yl)acetate
Matched Categories: … Blood and Blood Forming Organs …
Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.
Approved
Matched Synonyms: … Iodine ioflupane (123I) …
Matched Description: … Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes …
Matched Categories: … Iodine Radioisotopes ... Iodine (123I) Compounds ... iodine ioflupane (123I) …
Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR) gene transcribe the chimeric protein...
Approved
Investigational
Matched Synonyms: … Anhydrous dasatinib ... Dasatinib anhydrous ... dasatinib (anhydrous) …
Matched Description: … [A2226,A11377] Also, mutations in the kinase domain of BCR-ABL may lead to relapse during imatinib treatment ... pathogenesis of CML and 15-30% of ALL cases. ... A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sulfur Compounds …
Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to erythromycin, azithromycin, or clarithromycin. It was shown to be more effective against certain Gram-negative bacteria, particularly Legionella pneumophila. Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with bacterial protein synthesis. It is...
Approved
Investigational
Withdrawn
Matched Synonyms: … (9E)-erythromycin 9-(O-((2-methoxyethoxy)methyl)oxime) …
Matched Description: … Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar ... Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with ... It is marketed in Australia as a treatment for respiratory tract, urinary and soft tissue infections. …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins …
A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Approved
Investigational
Matched Synonyms: … Amifostine anhydrous
Matched Description: … It causes splenic vasodilation and may block autonomic ganglia. …
Matched Categories: … Sulfur Compounds …
Approved
Experimental
Matched Synonyms: … Ferric chloride, anhydrous
Zoledronic acid, or CGP 42'446, is a third generation, nitrogen containing bisphosphonate similar to ibandronic acid, minodronic acid, and risedronic acid. Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone.[L13712,L13715,L13721] Zoledronic acid...
Approved
Matched Synonyms: … Anhydrous Zoledronic Acid ... Zoledronic Acid Anhydrous ... Zoledronic Acid, Anhydrous
Matched Description: … third generation, nitrogen containing bisphosphonate similar to [ibandronic acid], [minodronic acid], and ... [A203111] Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia ... of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone. …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... zoledronic acid, calcium and colecalciferol, sequential …
Experimental
Matched Synonyms: … bis[5-chloro-1h-indol-2-yl-carbonyl-aminoethyl]-ethylene glycol …
Pentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.
Approved
Matched Synonyms: … Pentosan sulfuric polyester …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sulfur Acids ... Sulfuric Acids ... Sulfur Compounds …
Mecapegfilgrastim is under investigation in clinical trial NCT05463601 (Mecapegfilgrastim for the Prevention of Dalpiciclib -Induced Neutropenia in Advanced Breast Cancer).
Investigational
Matched Synonyms: … .-(((2-((3-(3-((3-aminopropyl)thio)-2,5-dioxo-1-pyrrolidinyl)-1-oxopropyl)amino)ethyl)amino)carbonyl) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium® in Hospitalized Patients With Coronavirus Disease COVID-19).
Investigational
Matched Synonyms: … Poly((1-(carboxymethyl)piperazin-1-ium-1,4-diyl bromide)ethylene-co-((piperazin-1,4-diyl 1-oxide)ethylene …
Matched Description: … Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium …
Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether. Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the United States as an adjunct to rest, physical therapy, and other measures for the relief of...
Approved
Vet approved
Matched Synonyms: … (RS)-2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate
Matched Iupac: … 2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate
Matched Description: … Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated ... [A178450] Methocarbamol tablets and intramuscular injections are prescription medicines indicated ... in the United States as an adjunct to rest, physical therapy, and other measures for the relief of discomforts …
Matched Mixtures name: … Methocarbamol and Aspirin ... Muscle and Back Pain Relief ... Muscle and Back Pain Relief Extra Strength …
Matched Categories: … Benzene Derivatives …
Experimental
Matched Name: … BENZYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE …
Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULFIDE WITH HUMAN-MOUSE ... IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULPHIDE WITH HUMAN-MOUSE …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Experimental
Matched Name: … Calcium magnesium potassium carbonate chloride hydroxide …
Matched Iupac: … calcium magnesium(2+) dipotassium(2+) chloride trihydroxide carbonate
Sanfetrinem cilexetil is under investigation in clinical trial NCT05388448 (EBA, Safety and Tolerability of Sanfetrinem Cilexetil).
Investigational
Matched Synonyms: … ,8b-octahydro-1-((r)-1-hydroxyethyl)-5-methoxy-2-oxoazeto(2,1-a)isoindole-4-carboxylate, cyclohexyl carbonate
Matched Description: … Sanfetrinem cilexetil is under investigation in clinical trial NCT05388448 (EBA, Safety and Tolerability …
Investigational
Matched Synonyms: … (3r)-1-azabicyclo(2.2.2)octan-3-yl (3-fluorophenyl)((3,4,5-trifluorophenyl)methyl)carbamate
Fasitibant is under investigation in clinical trial NCT02205814 (Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee).
Investigational
Matched Synonyms: … 2,4-dichloro-3-(((2,4-dimethyl-8-quinolinyl)oxy)methyl)phenyl)sulfonyl)amino)tetrahydro-2h-pyran-4-yl)carbonyl
Matched Iupac: … -4-amino-5-{4-[4-(2,4-dichloro-3-{[(2,4-dimethylquinolin-8-yl)oxy]methyl}benzenesulfonamido)oxane-4-carbonyl
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sulfur Compounds …
One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Synonyms: … (2S,5R,6R)-6-({[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4- …
Matched Salts name: … Dicloxacillin sodium anhydrous
Matched Categories: … Sulfur Compounds …
Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Synonyms: … 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide …
Matched Description: … Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. ... in tumour cell proliferation and tumour angiogenesis. ... It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzene Derivatives …
Idasanutlin has been used in trials studying the treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and Neoplasms, Leukemia, Acute Myeloid Leukemia.
Investigational
Matched Synonyms: … (3-CHLORO-2-FLUOROPHENYL)-4-(4-CHLORO-2-FLUOROPHENYL)-4-CYANO-5-(2,2-DIMETHYLPROPYL)-2-PYRROLIDINYL)CARBONYL
Matched Description: … treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and
Matched Categories: … Benzene Derivatives …
Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-acetic acid. The pharmacological effect of indometacin is not fully understood,...
Approved
Investigational
Matched Synonyms: … {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid …
Matched Description: … indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and ... Indometacin was first discovered in 1963 and it was first approved for use in the U.S. by the Food and ... ocular inflammation and pain and/or complications after cataract surgery. …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... indometacin and antiinfectives ... Topical Products for Joint and Muscular Pain …
Experimental
Matched Synonyms: … 4-O-Sulfo-β-D-galactopyranose …
Glucose oxidase has been investigated for the treatment of Upper Respiratory Tract Infections.
Investigational
Matched Synonyms: … Glucose oxidase
Matched Name: … Glucose oxidase
Matched Description: … Glucose oxidase has been investigated for the treatment of Upper Respiratory Tract Infections. …
Matched Categories: … Enzymes and Coenzymes …
Displaying drugs 1051 - 1075 of 1648 in total