Displaying drugs 1051 - 1075 of 14715 in total
Mechlorethamine
A vesicant and necrotizing irritant destructive to mucous membranes, mechlorethamine is an alkylating drug. It was formerly used as a war gas. The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. It causes severe gastrointestinal and bone marrow damage.
The FDA granted marketing approval for the orphan...
Approved
Investigational
Matched Description: … It causes severe gastrointestinal and bone marrow damage. ... The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. ... A vesicant and necrotizing irritant destructive to mucous membranes, mechlorethamine is an alkylating …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Mefenamic acid
A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Approved
Matched Description: … A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Iohexol
Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Approved
Matched Description: … Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality. ... water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and …
Polidocanol
Polidocanol is a sclerosing agent indicated to treat uncomplicated spider veins (varicose veins ≤1 mm in diameter) and uncomplicated reticular veins (varicose veins 1 to 3 mm in diameter) in the lower extremity. It is marketed under the brand names Asclera and Varithena. The formula for Polidocanol has the structural...
Approved
Matched Description: … It is marketed under the brand names Asclera and Varithena. ... a sclerosing agent indicated to treat uncomplicated spider veins (varicose veins ≤1 mm in diameter) and ... has the structural formula C12H25(OCH2CH2)nOH, a mean extent of polymerization (n) of approximately 9 and …
Rotavirus vaccine
Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the...
Approved
Matched Description: … Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially ... L1117] Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and …
Enmetazobactam
Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious infections. The combination product of enmetazobactam and cefepime was first approved by the FDA on February...
Approved
Matched Description: … ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and ... [A263276]
The combination product of enmetazobactam and [cefepime] was first approved by the FDA …
Icodextrin
Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers. It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease. It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport...
Approved
Investigational
Matched Description: … It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal …
Pindolol
Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. Early research into the use of pindolol found it had chronotropic effects, and so further investigation focused on the treatment of arrhythmia. Research into pindolol's use in the treatment of hypertension began in the early 1970s....
Approved
Investigational
Matched Description: … [L32353] Early research into the use of pindolol found it had chronotropic effects, and so further investigation …
Matched Categories: … pindolol and other diuretics …
Matched Categories: … pindolol and other diuretics …
Crotalus adamanteus antivenin
Each year it is estimated there are 45,000 snakebites in the US and 300,000 to 400,000 bites worldwide. About 8000 of these snakebites involve venomous snake species. The majority of people bitten are males and about 50% occur in the age group of 18 to 28 .
The eastern diamondback...
Approved
Experimental
Matched Description: … Each year it is estimated there are 45,000 snakebites in the US and 300,000 to 400,000 bites worldwide ... isolating the antivenin of interest through fractionation and chromatography techniques. ... The majority of people bitten are males and about 50% occur in the age group of 18 to 28 [F116]. …
Upadacitinib
Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic drug (DMARD) used in the treatment of rheumatoid arthritis to slow down disease progression. Rheumatoid arthritis is a chronic autoimmune inflammatory disease affecting the peripheral joints. It is characterized by synovial inflammation and hyperplasia, autoantibody production, cartilage damage...
Approved
Investigational
Matched Description: … and bone destruction, leading to co-morbidities. ... Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic ... It is characterized by synovial inflammation and hyperplasia, autoantibody production, cartilage damage …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Pizotifen
Pizotifen belongs to the class of antamines and is related to cyproheptadine. It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention for many years. It exhibits weak anticholinergic, antihistamine, and antikinin actions in addition to sedative and appetite-stimulating properties . Some patients receiving pizotifen...
Approved
Matched Description: … It exhibits weak anticholinergic, antihistamine, and antikinin actions in addition to sedative and appetite-stimulating ... Pizotifen belongs to the class of antamines and is related to [cyproheptadine]. ... [A32532] It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention …
Carboxin
A systemic agricultural fungicide and seed treatment agent.
Approved
Experimental
Matched Description: … A systemic agricultural fungicide and seed treatment agent. …
Ebola Zaire vaccine (live, attenuated)
Ebola virus vaccine is a vaccine used to prevent Ebola virus disease caused by Zaire ebolavirus in adults, prevent outbreaks, and reduce the extent of the virus spreading in case of outbreaks. Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a rare but severe and often deadly disease....
Approved
Matched Description: … and external bleeding. ... These may be accompanied by hypotension and respiratory, kidney and liver failure, as well as internal ... total deaths during this time in Guinea, Liberia, and Sierra Leone. …
Finafloxacin
Finafloxacin is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Finafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December 2014.
Approved
Investigational
Matched Description: … the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and ... Finafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December …
Bifonazole
Bifonazole is an azole antifungal drug.
Approved
Investigational
Matched Categories: … Imidazole and Triazole Derivatives …
Midodrine
An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Approved
Matched Categories: … Adrenergic and Dopaminergic Agents …
Tavaborole
Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to Trichophyton rubrum or Trichophyton mentagrophytes infection. Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis...
Approved
Investigational
Matched Description: … boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and ... inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and …
Betahistine
Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408]
Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Description: … It has a significant impact on both the physical and social functioning of affected individuals. ... Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing …
Recombinant stabilized RSV B prefusion F antigen
Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial virus (RSV) vaccine called Abrysvo. The vaccine comprises two antigens - the other being recombinant stabilized RSV A prefusion F antigen - which have been expressed in Chinese hamster ovary cell lines and then purified...
Approved
Matched Description: … then purified and lyophilized. ... stabilized RSV A prefusion F antigen] - which have been expressed in Chinese hamster ovary cell lines and ... virus vaccine, adjuvanted] (Arexvy), Abrysvo is reconstituted with sterile water prior to injection and …
Choline magnesium trisalicylate
Choline magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug. Trisalicylate significantly reduces methotrexate renal clearance, displacing methotrexate from protein, increasing the fraction unbound by 28% [A19653, A19654].
Approved
Ribostamycin
Ribostamycin is an aminoglycoside antibiotic isolated from Streptomyces ribosidificus listed as one of the World Health Organization's critically important antimicrobials.
Approved
Experimental
Fursultiamine
Compound used for therapy of thiamine deficiency. It has also been suggested for several non-deficiency disorders but has not yet proven useful. Fursultiamine is a vitamin B1 derivative.
Approved
Meglumine
Approved
Brilliant green cation
Brilliant green, or ethanaminium, is a derivative of triarylmethane dye that has been used as a dye to color silk and wool. Due to its inhibitory actions against Gram positive microorganisms, brilliant green can be found in antiseptic products such as solutions and swabs used to prevent infection.
Approved
Vet approved
Matched Description: … green, or ethanaminium, is a derivative of triarylmethane dye that has been used as a dye to color silk and ... Gram positive microorganisms, brilliant green can be found in antiseptic products such as solutions and …
Displaying drugs 1051 - 1075 of 14715 in total