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Displaying drugs 10851 - 10875 of 12376 in total

Safrazine

Safrazine is a member of the hydrazine family with non-selective and irreversible inhibitor effects against monoamine oxidases. In 1960, it was used as an antidepressant but it is now discontinued.
Withdrawn
Matched Iupac: … [4-(2H-1,3-benzodioxol-5-yl)butan-2-yl]hydrazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Imidapril

Imidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.
Investigational
Matched Iupac: … (4S)-3-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-1-methyl-2-oxoimidazolidine- ... 4-carboxylic acid …
Matched Salts cas: … 89396-94-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Lorcainide

Experimental
Matched Iupac: … N-(4-chlorophenyl)-2-phenyl-N-[1-(propan-2-yl)piperidin-4-yl]acetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Metenkefalin

Metenkefalin is an endogenous opioid and beta-endorphin. It has been shown to reduce chromosomal abberations in patients with multiple sclerosis. Metenkefalin, along with tridecactide, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]
Investigational
Matched Iupac: … (2S)-2-[(2S)-2-(2-{2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]acetamido}acetamido)-3-phenylpropanamido ... ]-4-(methylsulfanyl)butanoic acid …

Phenylalanylamide

Experimental
Matched Synonyms: … (S)-2-amino-3-phenylpropanamide …
Matched Iupac: … (2S)-2-amino-3-phenylpropanamide …

NUC-7738

NUC-7738 is under investigation in clinical trial NCT03829254 (A Safety, Pharmacokinetic and Clinical Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma).
Investigational
Matched Synonyms: … L-Alanine, N-(3′-deoxy-P-phenyl-5′-adenylyl)-, phenylmethyl ester (ACI) …

O-(((1R)-((N-PHENYLMETHOXYCARBONYL-L-ALANYL)AMINO)ETHYL)HYDROXYPHOSPHONO)-L-BENZYLACETIC ACID

Experimental
Matched Iupac: … (2S)-2-({[(1R)-1-[(2S)-2-{[(benzyloxy)carbonyl]amino}propanamido]ethyl](hydroxy)phosphoryl}oxy)-3-phenylpropanoic …

Mangostin

Mangostin is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … 7-o-methyl-4-desprenylcostatin …
Matched Categories: … Heterocyclic Compounds, 3-Ring …

(2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E)-OCTADEC-9-ENOATE

Experimental
Matched Name: … (2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E …
Matched Iupac: … [(2R)-2,3-dihydroxypropoxy][(2R)-2-[(9Z)-hexadec-9-enoyloxy]-3-[(9Z)-octadec-9-enoyloxy]propoxy]phosphinic …

Seviteronel

Seviteronel has been used in trials studying the treatment of CRPC, Prostate Cancer, and Castration-resistant Prostate Cancer.
Investigational
Matched Iupac: … (1S)-1-[6,7-bis(difluoromethoxy)naphthalen-2-yl]-2-methyl-1-(1H-1,2,3-triazol-5-yl)propan-1-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Somatropin pegol

Somatropin pegol is under investigation in clinical trial NCT00715689 (Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083).
Investigational

Buthionine sulfoximine

Buthionine sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin).
Investigational
Matched Synonyms: … Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)- …
Matched Iupac: … 2-amino-4-[butyl(imino)oxo-lambda6-sulfanyl]butanoic acid …

2-Oxy-4-Hydroxy-5-(2-Hydrazinopyridine)Phenylalanine

Experimental
Matched Name: … 2-Oxy-4-Hydroxy-5-(2-Hydrazinopyridine)Phenylalanine …
Matched Iupac: … (2S)-2-amino-3-[(1R)-4-hydroxy-6-oxo-3-[2-(pyridin-2-yl)hydrazin-1-yl]cyclohexa-2,4-dien-1-yl]propanoic …

O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE

Experimental
Matched Name: … O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE …
Matched Iupac: … 4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benzene-1-sulfonamide …

difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron

Experimental
Matched Iupac: … 12-(4-carboxybutyl)-2,2-difluoro-4-octyl-1lambda5,3-diaza-2-boratricyclo[7.3.0.0^{3,7}]dodeca-1(12),4,6,8,10 ... -pentaen-1-ylium-2-uide …

11-[(MERCAPTOCARBONYL)OXY]UNDECANOIC ACID

Experimental

Strychnine

Experimental
Matched Salts cas: … 60-41-3 …

Bisindolylmaleimide I

Experimental
Matched Iupac: … 3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Lofentanil

Lofentanil is an analog of fentanyl and is one of the most potent opioids available today. It displays most similarity to carfentanil (4-carbomethoxyfentanyl) and is considered to be slightly more potent than this drug.
Illicit
Matched Iupac: … methyl (3R,4S)-3-methyl-1-(2-phenylethyl)-4-(N-phenylpropanamido)piperidine-4-carboxylate …
Matched Description: … It displays most similarity to carfentanil (4-carbomethoxyfentanyl) and is considered to be slightly …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Bindarit

Bindarit has been used in trials studying the prevention and treatment of Coronary Restenosis and Diabetic Nephropathy.
Investigational
Matched Iupac: … 2-[(1-benzyl-1H-indazol-3-yl)methoxy]-2-methylpropanoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Alphaprodine

Illicit
Matched Iupac: … (3R,4S)-1,3-dimethyl-4-phenylpiperidin-4-yl propanoate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Tiemonium iodide

Experimental
Matched Iupac: … 4-[3-hydroxy-3-phenyl-3-(thiophen-2-yl)propyl]-4-methylmorpholin-4-ium iodide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Cobalamin

Experimental
Matched Iupac: … yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl phosphono]oxy}propyl]carbamoyl}ethyl)-2,3,6,8,13,13,16,18- ... octamethyl-20,21,22,23-tetraazapentacyclo[15.2.1.1^{2,5}.1^{7,10}.1^{12,15}]tricosa-5(23),6,10(22),11,15 ... carbamoylethyl)-3,8,19-tris(carbamoylmethyl)-18-(2-{[(2S)-2-{[(2R,3S,4R,5S)-5-(5,6-dimethyl-1H-1,3-benzodiazol-1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds with 4 or More Rings …

Ensitrelvir

Ensitrelvir is under investigation in clinical trial NCT05605093 (Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE): Shionogi Protease Inhibitor (Ensitrelvir)).
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Tylosin

Tylosin is a bacteriostatic macrolide antibiotic and feed additive used in veterinary medicine. It has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative organisms. Tylosin is produced as a fermentation product of Streptomyces fradiae.
Vet approved
Matched Iupac: … 3,4-dimethoxy-6-methyloxan-2-yl]oxy}methyl)-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien ... (dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-16-ethyl-4-hydroxy-15-({[(2R,3R,4R,5R,6R)-5-hydroxy- ... 9R,11E,13E,15R,16R)-6-{[(2R,3R,4R,5S,6R)-5-{[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy}-4- …
Matched Salts cas: … 1405-53-4 …
Displaying drugs 10851 - 10875 of 12376 in total