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Displaying drugs 1076 - 1100 of 1373 in total

Vigabatrin

Vigabatrin is an analog of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms. It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA. Although administered as a racemic mixture, only the...
Approved
Matched Description: … [A202124] Its use is now generally reserved for patients who have failed alternative therapies, and its ... inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and ... [A202037] It was first introduced as an antiepileptic agent in the United Kingdom in 1989 and was …
Matched Products: … Vigabatrin for Oral Solution ... Vigabatrin for oral solution USP, 500 mg …

Benzyl benzoate

Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so...
Approved
Matched Description: … Benzyl benzoate is not the treatment of choice for scabies due to its irritant properties. ... It is also used to treat lice infestation of the head and body. ... Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. …
Matched Categories: … Scabicides, Insecticides and Repellents ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … SCABİN %25 FORT LİKİT …

Thiocolchicoside

Thiocolchicoside is a semi-synthetic derivative of the colchicine, a natural anti-inflammatory glycoside which originates from the flower seeds of Superba gloriosa. It is a muscle relaxant with anti-inflammatory and analgesic effects. It has potent convulsant activity and should not be administered to individuals prone to seizures.
Experimental
Matched Description: … It is a muscle relaxant with anti-inflammatory and analgesic effects. ... It has potent convulsant activity and should not be administered to individuals prone to seizures. …
Matched Mixtures name: … TIOMED® FORTE ... TIOMED® FORTE …
Matched Products: … MYAL FORT 8 MG KAPSUL, 10 ADET ... MYAL FORT 8 MG KAPSUL, 14 ADET ... MYAL FORT 8 MG KAPSUL, 20 ADET …

Technetium Tc-99m sestamibi

Technetium Tc-99m sestamibi (commonly sestamibi) is a pharmaceutical agent used in nuclear medicine imaging. The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six methoxyisobutylisonitrile (MIBI) ligands, hence the name sesta (6) MIBI.. Following intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by...
Approved
Investigational
Matched Description: … for: 1) detecting coronary artery disease by localizing myocardial ischemia (reversible defects) and ... infarction (non-reversible defects); and 2) evaluating myocardial function and developing information ... for use in patient management decisions. …
Matched Categories: … Indicators and Reagents …
Matched Products: … Kit for the Preparation of Technetium Tc99m Sestamibi …

Nefopam

Nefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. Nefopam has been investigated for the prevention of Kidney Transplantation.
Approved
Investigational
Matched Description: … Nefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. ... Nefopam has been investigated for the prevention of Kidney Transplantation. …
Matched Products: … ACUPAN SOLUTION FOR INJECTION 20MG/2ML …

Methylnaltrexone

Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms. It is also a weak CYP2D6 inhibitor. FDA approved in 2008.
Approved
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Constipation …
Matched Products: … Relistor Solution For Injection 12mg/0.6mL …

Spectinomycin

An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
Approved
Investigational
Vet approved
Matched Description: … It is active against gram-negative bacteria and used for the treatment of gonorrhea. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … TROBICIN FOR INJECTION 2 g/vial …

(2r)-2-{[Formyl(Hydroxy)Amino]Methyl}Hexanoic Acid

Experimental
Matched Name: … (2r)-2-{[Formyl(Hydroxy)Amino]Methyl}Hexanoic Acid …

Dactinomycin

A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin...
Approved
Investigational
Matched Description: … It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … DACTINOMYCIN FOR INJECTION 0.5 mg/vial …

Colistimethate

Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa.
Approved
Vet approved
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Colistimethate for Injection ... Colistimethate for Injection U.S.P. ... Colistimethate for Injection USP …

Japanese encephalitis virus strain sa 14-14-2 antigen (formaldehyde inactivated)

Approved
Matched Products: … IXIARO Suspension for Injection 0.5ml in pre-filled syringe …

Cefazolin

A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Approved
Matched Description: … It attains high serum levels and is excreted quickly via the urine. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … CEFAZOLIN ALVOGEN POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL ... Cefazolin for Injection ... Cefazolin for Injection USP …

Cloprostenol

Vet approved
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Matched Products: … GESTAVET PROST (d-cloprostenol 75 mcg/ml solution for injection) …

Trabectedin

Trabectedin, also referred as ET-743 during its development, is a marine-derived antitumor agent discovered in the Carribean tunicate Ecteinascidia turbinata and now produced synthetically. Trabectedin has a unique mechanism of action. It binds to the minor groove of DNA interfering with cell division and genetic transcription processes and DNA repair...
Approved
Investigational
Matched Description: … It is approved for use in Europe, Russia and South Korea for the treatment of advanced soft tissue sarcoma ... and ovarian cancer. ... and DNA repair machinery. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … YONDELIS 1MG FOR INJECTION ... YONDELIS Powder for Injection 1mg/vial …

Nusinersen

An antisense oligonucleotide that induces survival motor neuron (SMN) protein expression, it was approved by the U.S. FDA in December, 2016 as Spinraza for the treatment of children and adults with spinal muscular atrophy (SMA). It is adminstrated as direct intrathecal injection.
Approved
Investigational
Matched Description: … FDA in December, 2016 as Spinraza for the treatment of children and adults with spinal muscular atrophy …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Spinraza 12 mg Solution for Injection …

Filgrastim

Filgrastim is a short-acting recombinant, non-pegylated human granulocyte colony-stimulating factor (G-CSF) analog produced by recombinant DNA technology. It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in E. Coli. Human...
Approved
Matched Description: … has an N-terminal methionine added in the sequence for expression in _E. ... peripheral blood for collection by leukapheresis in patients undergoing peripheral blood progenitor ... cell collection and therapy. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Nivestim 120mcg/0.2mL Solution for Injection/Infusion ... Nivestim 480mcg/0.5mL Solution for Injection/ Infusion ... Nivestim 300mcg/0.5mL Solution for Injection/Infusion …

Influenza A virus A/Vietnam/1194/2004 (H5N1) antigen (formaldehyde inactivated)

Approved
Matched Products: … Pandemic Influenza Vaccine H5N1 Baxter Suspension for Injection …

Rofecoxib

Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 )...
Approved
Investigational
Withdrawn
Matched Description: … Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and ... doses of 125, 25, and 50 mg is approximately 93%. ... The proteins that rofecoxib target include elastin and prostaglandin G/H synthase 2. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … REOX 25 MG FORT TABLET, 14 ADET ... REOX 25 MG FORT TABLET, 28 ADET …

Remifentanil

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Description: … pain relief and adjunctive to an anaesthetic. ... causes respiratory depression and analgesia. ... Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for …
Matched Categories: … Hypnotics and Sedatives ... Fentanyl and fentanyl analogues …
Matched Products: … Remifentanil Reig Jofre 5mg Powder for Concentrate for Solution for Injection or Infusion ... Remifentanil for Injection ... ULTIVA FOR INJECTION 1 mg/vial …

Methylprednisolone hemisuccinate

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Approved
Matched Description: … A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … MEDASON FOR INJECTION ... Medixon Powder for Injection 500 mg ... SOLU-MEDROL FOR INJECTION 500 mg/8 ml …

Verteporfin

Verteporfin, marketed as Visudyne, is a benzoporphyrin derivative comprising a 50:50 mixture of two isomers: CL-315555 and CL-315585. It is used as a photosensitizer in photodynamic therapy to eliminate abnormal blood vessels in wet form macular degeneration. Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red...
Approved
Investigational
Matched Description: … It is used as a photosensitizer in photodynamic therapy to eliminate abnormal blood vessels in wet form ... as Visudyne, is a benzoporphyrin derivative comprising a 50:50 mixture of two isomers: [CL-315555] and ... Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red light …
Matched Products: … VISUDYNE FOR INJECTION 15 mg/vial …

Bupivacaine

Bupivacaine is a widely used local anesthetic agent.
Approved
Investigational
Matched Mixtures name: … Sensorcaine Forte ... Bupivacaine Hci and Epinephrine ... Bupivacaine Hydrochloride and Epinephrine …
Matched Categories: … bupivacaine and meloxicam …
Matched Products: … Regivell Heavy 0.5% Solution for Injection ... Bupicaine D 0.5% w/v Solution for Injection ... BUPIVACAINE-BAXTER SOLUTION FOR INJECTION 5 MG/ML …

Lutropin alfa

Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units. Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for use in...
Approved
Matched Description: … Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for ... biological activity of endogenous LH; an acute rise of LH, or LH surge, in females triggers ovulation and …
Matched Mixtures name: … Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Sex Hormones and Modulators of the Genital System …
Matched Products: … LUVERIS FOR INJECTION 75 iu/vial (Revised formula) …

Imidapril

Imidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.
Investigational
Matched Description: … Imidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant. …
Matched Products: … PRILIUM 150MG POWDER FOR ORAL SOLUTION …

Ganirelix

Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported...
Approved
Matched Description: … Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist ... Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … ORGALUTRAN SOLUTION FOR INJECTION 0.25 mg/0.5 ml ... ORGALUTRAN 0.25MG/0.5ML (SOLUTION FOR INJECTION) …
Displaying drugs 1076 - 1100 of 1373 in total