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Displaying drugs 1076 - 1100 of 1345 in total
Elsubrutinib is under investigation in clinical trial NCT04451772 (A Study of the Safety of Oral Elsubrutinib Capsules and Oral Upadacitinib Tablets Given Alone or in Combination (ABBV-599) for Adult Participants With Moderately to Severely Active Systemic Lupus Erythematosus to Assess Change in Disease State).
Investigational
Matched Synonyms: … (s)-4-(1-acryloylpiperidin-3-yl)-1h-indole-7-carboxamide ... 4-((3s)-1-(prop-2-enoyl)-piperidin-3-yl)-1h-indole-7-carboxamide ... 1h-indole-7-carboxamide, 4-((3s)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl)- …
Experimental
Matched Synonyms: … 1,2-bis(2-(5-chloroindole-2-carbonylamino)ethoxy)ethane ... bis[5-chloro-1h-indol-2-yl-carbonyl-aminoethyl]-ethylene glycol ... N,N'-[1,2-Ethanediylbis(oxy-2,1-ethanediyl)]bis(5-chloro-1H-indole-2-carboxamide) …
Matched Iupac: … 5-chloro-N-[2-(2-{2-[(5-chloro-1H-indol-2-yl)formamido]ethoxy}ethoxy)ethyl]-1H-indole-2-carboxamide
Investigational
Matched Iupac: … N'-(pyrrolidine-1-carboximidoyl)-N-[4-(trifluoromethoxy)phenyl]guanidine …
Investigational
Matched Synonyms: … (1,5-a)pyrimidine-3-carboxamide ... )carbonyl)-1-piperidinyl)-3-pyridinyl)- ... 2-amino-6-fluoro-n-(5-fluoro-4-(4-((4-(oxetan-3-yl)piperazin-1-yl)carbonyl)-1-piperidyl)-3-pyridyl)pyrazolo …
Experimental
Matched Synonyms: … 2-Carboxy-4'-(dimethylamino)azobenzene ... 4-Dimethylamino-2'-carboxylazobenzene ... 4'-Dimethylaminoazobenzene-2-carboxylic acid …
Vitamin A-analog that increases diffusivity of oxygen in aqueous solutions, including plasma.
Investigational
Matched Synonyms: … 8,8'-diapo-8,8'-carotenedioic acid ... 8,8'-diapo-ψ,ψ-carotenedioic acid …
Matched Categories: … Carotenoids
Investigational
Matched Synonyms: … 4-[[[(4-Fluorophenyl)amino]carbonyl]amino]benzenesulfonamide ... Benzenesulfonamide, 4-[[[(4-fluorophenyl)amino]carbonyl]amino]- …
Experimental
Matched Synonyms: … (p-carboxyphenyl)hydroxymercury …
Matched Iupac: … (4-carboxyphenyl)mercurol …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
PCL-016 or Picolinic acid drug substance is a pyridine carboxylate metabolite of tryptophan. It acts as an anti-infective and immunomodulator and is produced in approximately 25-50 mg quantities by the body on a daily basis through the breakdown of tryptophan. PCL-016 plays a key role in zinc transport. As a...
Investigational
Matched Synonyms: … 2-Carboxypyridine
Matched Iupac: … pyridine-2-carboxylic acid …
Matched Description: … PCL-016 or Picolinic acid drug substance is a pyridine carboxylate metabolite of tryptophan. …
A orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor independent of oxygen availability.
Investigational
Matched Synonyms: … (((1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl)amino)acetic acid ... 1-Chloro-N- (hydroxyformylmethyl-4-hydroxyisoquinoline-3-carboxamide ... 1-Chloro-N-(hydroxyformylmethyl-4-hydroxyisoquinoline-3-carboxamide
Cerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. It is also shown to inhibit feeding and induce...
Experimental
Matched Synonyms: … (2R,3S)-3-((4E,7E)-nona-4,7-dienoyl)oxirane-2-carboxamide ... (2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide …
Matched Iupac: … (2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboximidic acid …
Experimental
Matched Synonyms: … 2-carboxyaniline ... o-carboxyaniline
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
LY-2183240 is an inhibitor of endocannabinoid reuptake/breakdown.
Investigational
Matched Synonyms: … 5-(biphenyl-4-ylmethyl)-n,n-dimethyl-1h-tetrazole-1-carboxamide ... 1h-tetrazole-1-carboxamide, 5-((1,1'-biphenyl)-4-ylmethyl)-n,n-dimethyl- …
Matched Iupac: … 5-({[1,1'-biphenyl]-4-yl}methyl)-N,N-dimethyl-1H-1,2,3,4-tetrazole-1-carboxamide
Allisartan isoproxil is under investigation in clinical trial NCT03264352 (Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes).
Investigational
Matched Synonyms: … )-, (((1-METHYLETHOXY)CARBONYL)OXY)METHYL ESTER ... 1H-IMIDAZOLE-5-CARBOXYLIC ACID, 2-BUTYL-4-CHLORO-1-((2'-(2H-TETRAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)METHYL …
Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis).
Investigational
Matched Synonyms: … cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic
Matched Iupac: … cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic
Investigational
Matched Synonyms: … Bis(carboxyethyl)germanium sesquioxide ... 3-[[2-carboxyethyl(oxo)germyl]oxy-oxogermyl]propanoic acid ... Carboxyethylgermanium sesquioxide …
Matched Iupac: … bis((2-carboxyethyl)germanetris(ylium)) trioxidandiide …
Matched Categories: … Carboxylic Acids …
BMS-188797 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Synonyms: … 4-desacetylpaclitaxel 4-methyl carbonate
Investigational
Matched Synonyms: … N-4-carboxyphenylretinamide ... Retinamide, n-(4-carboxyphenyl)- …
Experimental
Matched Synonyms: … Oseltamivir carboxylate
Matched Iupac: … (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid …
Matched Categories: … Carboxylic Acids …
Experimental
Matched Synonyms: … tetra-dodecanoyl cardiolipin ... 1,1'2,2'-tetra-dodecanoyl cardiolipin ... 1,1'2,2'-tetrastearoyl cardiolipin
Matched Name: … Tetrastearoyl cardiolipin
Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. It is being investigated in cancers.[A257281,A257286]
Investigational
Matched Synonyms: … -(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido ... )bicyclo [2.2.2]octane-1-carboxylic acid ... )-amino)-bicyclo(2.2.2)octane-1-carboxylic acid …
Matched Iupac: … '',2''-dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indol]-5'-yl]amido}bicyclo[2.2.2]octane-1-carboxylic
Experimental
Matched Synonyms: … 3-methyl-7-amino-Δ3-cephem-4-carboxylic acid ... 3-methyl-7-aminoceph-3-em-4-carboxylic acid ... 7-amino-3-methyl-3-cephem-4-carboxylic acid …
Matched Iupac: … (6R,7R)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Imidazole-4-carboxylic acid is under investigation in clinical trial NCT00583895 (Safety and Efficacy Study of Imcooh Cream in Patients Suffering From Moderate Atopic Dermatitis).
Investigational
Matched Synonyms: … 4-Carboxyimidazole
Matched Name: … Imidazole-4-carboxylic acid …
Matched Iupac: … 1H-imidazole-4-carboxylic acid …
Matched Description: … Imidazole-4-carboxylic acid is under investigation in clinical trial NCT00583895 (Safety and Efficacy …
Experimental
Matched Synonyms: … (3-(N-Hydroxy)carboxamido-2-benzylpropanoyl)alanine …
Experimental
Matched Synonyms: … 3-phenyl-3-({[4-(4-pyridin-4-ylphenyl)thien-2-yl]carbonyl}amino)propanoic acid ... (3R)-3-Phenyl-3-[({4-[4-(4-pyridinyl)phenyl]-2-thienyl}carbonyl)amino]propanoic acid …
Displaying drugs 1076 - 1100 of 1345 in total