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Displaying drugs 11001 - 11025 of 13448 in total

Inosine

A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland,...
Experimental
Investigational
Matched Iupac: … 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purin-6-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

6-O-benzylguanine

6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others.
Investigational
Matched Iupac: … 6-(benzyloxy)-9H-purin-2-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Idalopirdine

Idalopirdine has been used in trials studying the treatment of Cognition, Schizophrenia, and Alzheimer's Disease.
Investigational
Matched Iupac: … [2-(6-fluoro-1H-indol-3-yl)ethyl]({[3-(2,2,3,3-tetrafluoropropoxy)phenyl]methyl})amine …
Matched Salts cas: … 467458-02-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Flortaucipir

Flortaucipir is under investigation in clinical trial NCT03507257 (Longitudinal Early-onset Alzheimer's Disease Study Protocol).
Investigational
Matched Iupac: … 2-fluoro-5-{5H-pyrido[4,3-b]indol-7-yl}pyridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …

6-Hydroxypropylthymine

Experimental
Matched Synonyms: … 6–(3-hydroxypropyl)thymine …
Matched Iupac: … 6-(3-hydroxypropyl)-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …

Indium In-111 satumomab pendetide

Tumor associated glycoprotein (TAG) 72 (B72.3) monoclonal antibody conjugated with Indium 111 for radioimaging colon tumors. Satumomab Pendetide (trade name: OncoScint®) is no longer commercially available.
Experimental
Withdrawn

Ladiratuzumab vedotin

Ladiratuzumab vedotin is under investigation in clinical trial NCT01969643 (A Safety Study of SGN-LIV1A in Breast Cancer Patients).
Investigational

(5-BROMO-4-CHLORO-3-INDOLYL)-A-D-MANNOSE

Experimental
Matched Name: … (5-BROMO-4-CHLORO-3-INDOLYL)-A-D-MANNOSE …
Matched Iupac: … (2R,3S,4S,5S,6R)-2-[(5-bromo-4-chloro-1H-indol-3-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol …

3,4-Dihydro-5-Methyl-Isoquinolinone

Experimental
Matched Iupac: … 5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one …

Pateclizumab

Pateclizumab is under investigation in clinical trial NCT01225393 (A Study to Evaluate the Efficacy and Safety of MLTA3698A in Combination With a Disease-Modifying Anti-Rheumatic Drug (DMARD) Compared With Adalimumab in Combination With a DMARD in Patients With Active Rheumatoid Arthritis).
Investigational

Agatolimod

Agatolimod is under investigation in clinical trial NCT00471471 (Vaccine Therapy in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery).
Investigational

6-hydroxy-FAD

Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[hydroxy({[(2R,3S,4S)-2,3,4 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …

Orbifloxacin

Orbifloxacin is a fluoroquinolone antibiotic. It is marketed by Schering-Plough Animal Health and approved for certain infections in dogs.
Vet approved
Matched Iupac: … 1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-5,6,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Sarafloxacin

Sarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.
Vet approved
Withdrawn
Matched Iupac: … 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Epicillin

Experimental
Matched Iupac: … (2S,5R,6R)-6-[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... [3.2.0]heptane-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Lorajmine

Experimental
Matched Iupac: … -8-methyl-8,15-diazahexacyclo[14.2.1.0^{1,9}.0^{2,7}.0^{10,15}.0^{12,17}]nonadeca-2,4,6-trien-18-yl 2- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Menaquinone 6

Menaquinone 6 is under investigation in clinical trial NCT01194778 (Comparison of Efficacy of Different Dosages Vitamin K2).
Investigational
Matched Iupac: … 2-[(2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl]-3-methyl-1,4- …
Matched Categories: … Vitamin K 2 …

Ricinoleic acid

Experimental

AZD-7762

AZD7762 has been investigated for the treatment of Cancer, Solid Tumors, and Advanced Solid Malignancies.
Investigational
Matched Iupac: … 3-(carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-piperidin-3-yl]thiophene-2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

1-Deoxy-D-xylulose 5-phosphate

1-Deoxy-D-xylulose 5-phosphate is a solid. This compound belongs to the pentose phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups. The proteins that 1-Deoxy-D-xylulose 5-phosphate targets include 1-Deoxy-D-xylulose 5-phosphate reductoisomerase and pyridoxine 5'-phosphate synthase. 1-Deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway.
Experimental
Matched Name: … 1-Deoxy-D-xylulose 5-phosphate …
Matched Description: … The proteins that 1-Deoxy-D-xylulose 5-phosphate targets include 1-Deoxy-D-xylulose 5-phosphate reductoisomerase ... 1-Deoxy-D-xylulose 5-phosphate is a solid. This compound belongs to the pentose phosphates. ... and pyridoxine 5'-phosphate synthase. 1-Deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate …

Alvocidib

Alvocidib is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment of cancer. It works by inhibiting cyclin-dependent kinases, arresting cell division and causing apoptosis in non-small lung cancer cells.
Experimental
Investigational
Matched Iupac: … 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

Ceftezole

Experimental
Matched Iupac: … (6R,7R)-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido]-3-[(1,3,4-thiadiazol-2-ylsulfanyl)methyl]-5-thia ... -1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Cilansetron

Cilansetron is a 5HT-3 antagonist made by Solvay Pharmaceuticals that is currently under trial phase in the EU and US.
Investigational
Matched Iupac: … (12R)-12-[(2-methyl-1H-imidazol-1-yl)methyl]-1-azatetracyclo[7.6.1.0^{5,16}.0^{10,15}]hexadeca-5(16), …
Matched Description: … Cilansetron is a 5HT-3 antagonist made by Solvay Pharmaceuticals that is currently under trial phase …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …

Harmine

Experimental
Matched Iupac: … 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …

R-82913

Experimental
Matched Iupac: … (11S)-6-chloro-11-methyl-10-(3-methylbut-2-en-1-yl)-1,3,10-triazatricyclo[6.4.1.0^{4,13}]trideca-4(13 ... ),5,7-triene-2-thione …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Displaying drugs 11001 - 11025 of 13448 in total