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Displaying drugs 11426 - 11450 of 12677 in total
Batabulin
Batabulin is under investigation in clinical trial NCT00057382 (T138067 Versus Doxorubicin in Chemotherapy-naive, Unresectable, Hepatocellular Carcinoma Patients).
Investigational
Matched Description: … Batabulin is under investigation in clinical trial NCT00057382 (T138067 Versus Doxorubicin in Chemotherapy-naive …
GSK232802
GSK232802 is under investigation in clinical trial NCT00604825 (Treatment of Hot Flashes/flushes in Postmenopausal Women (WARM Study)).
Investigational
Matched Description: … GSK232802 is under investigation in clinical trial NCT00604825 (Treatment of Hot Flashes/flushes in Postmenopausal …
Dopastatin
Dopastatin is under investigation in clinical trial NCT04335357 (TBR-760 in Adult Patients With Non-functioning Pituitary Adenomas).
Investigational
Matched Description: … Dopastatin is under investigation in clinical trial NCT04335357 (TBR-760 in Adult Patients With Non-functioning …
STG-001
STG-001 is under investigation in clinical trial NCT04489511 (Study of STG-001 in Subjects With Stargardt Disease).
Investigational
Matched Description: … STG-001 is under investigation in clinical trial NCT04489511 (Study of STG-001 in Subjects With Stargardt …
PF-04856884
PF-04856884 or CVX-060 is a selective angiopoietin (Ang)-2 inhibitor. It is under investigation in clinical trial NCT01441414 (PF-04856884 (CVX-060) in Combination With Axitinib in Patients With Previously Treated Metastatic Renal Cell Carcinoma).
Investigational
Matched Description: … [A257291] It is under investigation in clinical trial NCT01441414 (PF-04856884 (CVX-060) in Combination ... With Axitinib in Patients With Previously Treated Metastatic Renal Cell Carcinoma). …
Amolimogene
Amolimogene is an investigational therapeutic designed to specifically augment the body's defensive response to human papillomavirus (HPV). Amolimogene was biologically engineered as a targeted therapy for the treatment of cervical dysplasia.
Investigational
N-Formylmethionine
N-Formylmethionine is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.
Experimental
Matched Description: … This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic ... N-Formylmethionine is effective in the initiation of protein synthesis. …
10-hydroxycamptothecin
10-hydroxycamptothecin is under investigation in clinical trial NCT00956787 (Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS)).
Investigational
Matched Description: … 10-hydroxycamptothecin is under investigation in clinical trial NCT00956787 (Study of AR-67 (DB-67) in …
Icrucumab
Icrucumab is under investigation in clinical trial NCT01111604 (A Study of IMC-1121B or IMC-18F1 in Colorectal Cancer).
Investigational
Matched Description: … Icrucumab is under investigation in clinical trial NCT01111604 (A Study of IMC-1121B or IMC-18F1 in Colorectal …
Aganirsen
Aganirsen is under investigation in clinical trial NCT02947867 (Trial of Aganirsen in iCRVO Patients at Risk of Developing NVG).
Investigational
Matched Description: … Aganirsen is under investigation in clinical trial NCT02947867 (Trial of Aganirsen in iCRVO Patients …
Balixafortide
Balixafortide is under investigation in clinical trial NCT03786094 (Pivotal Study in HER2 Negative, Locally Recurrent or Metastatic Breast Cancer).
Investigational
Matched Description: … Balixafortide is under investigation in clinical trial NCT03786094 (Pivotal Study in HER2 Negative, Locally …
BMS-986158
BMS-986158 is under investigation in clinical trial NCT02419417 (Study of BMS-986158 in Subjects With Select Advanced Cancers).
Investigational
Matched Description: … BMS-986158 is under investigation in clinical trial NCT02419417 (Study of BMS-986158 in Subjects With …
Zagotenemab
Zagotenemab is under investigation in clinical trial NCT03518073 (A Study of LY3303560 in Participants With Early Symptomatic Alzheimer's Disease).
Investigational
Matched Description: … Zagotenemab is under investigation in clinical trial NCT03518073 (A Study of LY3303560 in Participants …
Bovhyaluronidase azoximer
Bovhyaluronidase azoximer is under investigation in clinical trial NCT06458543 (Optimization of Bacterial Vaginosis Treatment in Women of Reproductive Age).
Investigational
Matched Description: … Vaginosis Treatment in Women of Reproductive Age). ... Bovhyaluronidase azoximer is under investigation in clinical trial NCT06458543 (Optimization of Bacterial …
3'-phospho-5'-adenylyl sulfate
3'-phospho-5'-adenylyl sulfate is a key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate. It is formed from sulfate ion and ATP in a two-step process. This compound also is an important step in the process...
Experimental
Matched Description: … This compound also is an important step in the process of sulfur fixation in plants and microorganisms ... It is formed from sulfate ion and ATP in a two-step process. ... 3'-phospho-5'-adenylyl sulfate is a key intermediate in the formation by living cells of sulfate esters …
Ethyl pyruvate
CTI-01 (ethyl pyruvate) is a novel anti-inflammatory agent for the treatment of critical inflammatory conditions. CTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancreatitis, ischemia-reperfusion injury, sepsis, renal injury and endotoxemia.
Investigational
Matched Description: … CTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of …
Darinaparsin
Investigational
Bimosiamose
Investigational
Satraplatin
Satraplatin is a platinum compound that is currently under investigation as one treatment of patients with advanced prostate cancer who have failed previous chemotherapy. As an investigation drug, it has not yet received U.S. Food and Drug Administration (FDA) approval and is not available in retail pharmacies.
Investigational
Matched Description: … Food and Drug Administration (FDA) approval and is not available in retail pharmacies. …
EGS21
EGS21(TM) is a beta-D-glucosylceramide (GC) compound. It is a potential therapeutic for treating immune mediated disorders. GC is a glycolipid that has been shown by Enzo scientists and collaborators to act as an anti-inflammatory agent in animal model systems, and therefore is being evaluated as an important candidate drug in...
Investigational
Matched Description: … animal model systems, and therefore is being evaluated as an important candidate drug in the ... glycolipid that has been shown by Enzo scientists and collaborators to act as an anti-inflammatory agent in …
Prinomastat
Prinomastat is a synthetic hydroxamic acid derivative with potential antineoplastic activity. Prinomastat inhibits matrix metalloproteinases (MMPs) (specifically, MMP-2, 9, 13, and 14), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. As a lipophilic agent, prinomastat crosses the blood-brain barrier.
Investigational
MLN-977
MLN-977 is a small molecule compound that inhibits the production of leukotrienes, especially 5-lipoxygenase. It is developed by PharmaEngine to treat asthma and chronic obstructive pulmonary disease.
Investigational
ETC-588
ETC-588, or LUV (large unilamellar vesicles), is made of naturally occurring lipids that circulate through arteries to facilitate the role of high-density lipoprotein (HDL) in removing accumulated cholesterol and other lipids from cells including those in the arterial wall. LUV are capable of transporting excess cholesterol from the vasculature to...
Investigational
Matched Description: … removing accumulated cholesterol and other lipids from cells including those in the arterial wall. ... occurring lipids that circulate through arteries to facilitate the role of high-density lipoprotein (HDL) in ... It is believed that the removal of cholesterol by ETC-588 through this pathway may result in the reversal …
Teverelix
A synthetic decapeptide, water-soluble Gonadotropin-releasing hormone antagonist. It has reached phase II clinical trials.
Investigational
Displaying drugs 11426 - 11450 of 12677 in total